Navigation Links
Sanofi and Regeneron Report Positive Phase 2b Trial Results with Sarilumab in Rheumatoid Arthritis
Date:7/12/2011

kine-mediated inflammatory signaling cascade. Sarilumab was developed using Regeneron VelocImmune® antibody technology.  

About the MOBILITY TrialThe MOBILITY trial is a randomized, double-blind, placebo-controlled, multicenter, two-part, dose ranging and confirmatory study with an operationally seamless design, evaluating efficacy and safety of sarilumab on top of MTX in patients with active RA who are inadequate responders to MTX therapy.  The primary objective of part A of the dose ranging MOBILITY trial was to demonstrate that sarilumab on top of MTX is effective in reducing the signs and symptoms of RA at 12 weeks.  The five doses tested were 100 milligrams (mg) and 150 mg every week and 100 mg, 150 mg and 200 mg every other week.  The primary objective of part B of the MOBILITY trial will be to demonstrate that sarilumab on top of MTX is effective in reducing the signs and symptoms of RA at 24 weeks.  Further details about the MOBILITY trial are available at http://clinicaltrials.gov/ct2/results?term=SAR+153191+mobility.

About Rheumatoid ArthritisRheumatoid arthritis (RA) is a chronic systemic autoimmune disease affecting approximately 0.5%–1% of the global adult population.  Abnormal immune response causes an inflamed, thickened synovium, the membrane that lines the joint.  As synovitis expands, the inflammatory process can damage the bone and cartilage of the joint and the surrounding tissues.  RA-related inflammation can involve the heart and the lung.  In 10% of patients with RA the liver is affected. Complications of RA include anemia and leucopenia.  At times RA can be very painful and affect a person's ability to carry out everyday tasks.  Most people with RA experience periods when their symptoms worsen (flares or active disease) separated by periods in which the symptoms improve.
'/>"/>

SOURCE Regeneron Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Sanofi Divests Dermik Dermatology Unit to Valeant Pharmaceuticals International, Inc.
2. Sanofi Enters Into Research Collaboration with Weill Cornell Medical College to Discover New Treatments for Tuberculosis
3. Sanofi Pasteur Commends Winners of International BioGENEius Challenge
4. Sanofi Announces Positive Results from the "All to Target" Study Evaluating Two Lantus® and Apidra® Regimens Versus Premixed Regimen
5. Medco, United BioSource and Sanofi Signed Global Agreement to Improve Quality of Patient Care Through Real-World Evidence
6. Sanofi Enters Into Research Collaboration With Biopharmaceutical Company Audion Therapeutics to Develop Potential Treatments for Hearing Loss
7. Sanofi Pasteur Donates Tdap Vaccine to Aid Storm Victims
8. sanofi-aventis: Strong Performance of Growth Platforms in Q1 2011
9. Sanofi Pasteur Announces FDA Approval of Menactra Meningococcal Conjugate Vaccine Indication for Infants
10. Sanofi-aventis Enters into Collaboration Agreement with Stanford University Bio-X to Focus on Early-Stage Scientific Research
11. Sanofi-Aventis Completes Acquisition of Genzyme Corporation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... , Nov. 26, 2014   Royal Philips ... today announced expanded availability of its portfolio of ... MobileDiagnost wDR, MobileDiagnost Opta[i] , ProGrade and PrimaryDiagnost[ii]. ... now available in the U.S., and availability of ... portfolio offers Philips, customers innovative solutions designed to ...
(Date:11/26/2014)... , Nov. 26, 2014 Lexicon ... announced the completion of previously announced concurrent financing ... After fees and estimated offering expenses, Lexicon anticipates ... transactions.  The transactions consisted of: , ... stock, pursuant to a registration statement that has ...
(Date:11/26/2014)... LOUIS , Nov. 26, 2014 Scott Steiger ... seen most of the world. As an engineer for the past ... a member of the military service. He,s been to six of ... Photo - http://photos.prnewswire.com/prnh/20141126/161076 Photo - ... specifically for travelers, he has a pretty good idea of what,s ...
Breaking Medicine Technology:Philips expands global reach of diagnostic X-Ray solutions 2Philips expands global reach of diagnostic X-Ray solutions 3Lexicon Announces Completion Of $280 Million In Financing Transactions 2Lexicon Announces Completion Of $280 Million In Financing Transactions 3Steiger Has Created the First Pill Case Specifically Designed For Travel 2
... Oct. 21 Reportlinker.com announces that a new market research report ... Market http://www.reportlinker.com/p0316091/Indian-Bulk-Drug-Market.html Indian bulk ... Indian Bulk Drug industry is expected to grow at ... per a Cygnus study. Cygnus estimates the size of Indian bulk ...
... Diplomat Specialty Pharmacy, the nation,s largest privately owned specialty ... innovative, web based tool designed to educate and train ... educational programs is the immediate focus of Jennifer Hagerman, ... Education and reports directly to Jeff Rowe, Senior Vice ...
Cached Medicine Technology:Reportlinker Adds Indian Bulk Drug Market 2Reportlinker Adds Indian Bulk Drug Market 3Reportlinker Adds Indian Bulk Drug Market 4Reportlinker Adds Indian Bulk Drug Market 5Diplomat Specialty Pharmacy Launches Diplomat University - Hires Jennifer Hagerman, PharmD, Pharmacy Professor 2
(Date:11/28/2014)... November 29, 2014 Angelweddingdress.com, a ... new collection of Blue Color Styles ... provided: up to 80% off and free shipping ... buy discounted blue bridesmaid dresses for less at ... , Angelweddingdress.com is famous as a reliable dress ...
(Date:11/28/2014)... Yesterday on November 27th, 2014, Thanksgiving morning, Branches ... families from 8 different sites throughout Miami-Dade and Broward ... Florida on Thanksgiving Day. Over 1,400 volunteers worked very ... individual meals via assembly lines and passing them off ... turkey, stuffing, green beans, mashed potatoes, cranberry sauce, a ...
(Date:11/28/2014)... Pathways Home Health & Hospice is joining ... was created to encourage people to take action and ... causes. This online event, celebrated the Tuesday after ... holiday shopping season. #GivingTuesday is to charitable giving as ... to online commerce. , The goal of #GivingTuesday is ...
(Date:11/28/2014)... York, NY (PRWEB) November 28, 2014 ... cash-for-junk-cars companies, is expanding their service offerings to help ... York City, Philadelphia and Washington, D.C. metropolitan areas deal ... to sweep across a large part of the country. ... these areas resulting in hundreds of totaled, crashed and ...
(Date:11/28/2014)... York, New York (PRWEB) November 28, 2014 ... are continuing to move forward in New Jersey’s ... claims in a consolidated litigation established there is ... Case List updated on November 18th shows 1,293 ... was created for lawsuits that allege complications resulting ...
Breaking Medicine News(10 mins):Health News:Blue Color Styles of Bridesmaid Dresses from AngelWeddingDress.com are Available Now With Big Discounts 2Health News:Branches’ 14th Annual Thanksgiving Delivers 6,000+ Meals to Families in Need 2Health News:Pathways Home Health & Hospice Joins #GivingTuesday; Annual Holiday Encourages Local Charitable Giving 2Health News:Pathways Home Health & Hospice Joins #GivingTuesday; Annual Holiday Encourages Local Charitable Giving 3Health News:Junk-A-Car Expanding Service to Assist U.S. Car Owners That May be Affected by Severe Winter Storms 2Health News:Nearly 1,300 Mirena Lawsuits Now Filed in Consolidated New Jersey Litigation, Bernstein Liebhard LLP Reports 2Health News:Nearly 1,300 Mirena Lawsuits Now Filed in Consolidated New Jersey Litigation, Bernstein Liebhard LLP Reports 3
... Group NV together with the University of Cologne (DE) ... adult mesenchymal stem cells ("MSCs") from the lining ... the collection and cryopreservation of very high quantities of ... ,Mesenchymal stem cells (MSCs) are of great therapeutic potential ...
... the most common addiction all over the world, and a ... impact of tobacco in its various forms on human health, ... smoking. ,Tobacco generates about Rs.7,964 crore ... about Rs.27,661 crore, according to WHO estimates. ...
... therapies - combining two or more medications into ... options for pharmaceutical brand teams to pursue ... Information's report "Pharmaceutical Product Relaunch: Preserving Market Share ... reveals that 58% of companies that launch combination ...
... Calum Best has decided to enter rehab in order to get ... ,Calum, who was recently snapped in a sleazy romp ... bad stuffs. ,"Im a bad boy. I go ... do stupid debauched things with the wrong women. Ive been sowing ...
... provide oral cancer examinations for their patients, but many ... optimum intervals, according to a new study. ,With ... and of proper examination techniques, some dentists in Illinois ... detect oral cancers in their patients," said Charles LeHew ...
... have created a synthetic polymer that doesnt burn, making it ... so flammable they are sometimes referred to as solid ... chemicals that are added to many plastics before they can ... items. Some of these additives have been showing up in ...
Cached Medicine News:Health News:Significant Scientific Breakthrough in Stem Cell Banking 2Health News:Tobacco Menace and What can Be Done About It 2Health News:Tobacco Menace and What can Be Done About It 3Health News:Tobacco Menace and What can Be Done About It 4Health News:Combination Therapies Continue to Thrive Among Pharma Brands 2Health News:Dentists Need More Training in Oral Cancer Detection 2Health News:Dentists Need More Training in Oral Cancer Detection 3Health News:Scientists Create Fire-proof, Eco-friendly Plastic 2
... MaximEyes by First Insight is the ... records solution for eye care professionals. ... with Eyefinitys online servicesrequest VSP authorizations, ... MaximEyes offers EMR, scheduling, billing, demographics, ...
... software- RLISYS provides a ... Support, and Training exclusively ... Ophthalmology, and Opticianry- The ... allowing you to focus ...
... The Advia 120 hematology ... streamline laboratory workflow and ... This analyzer offers a ... assays, meeting the needs ...
The K-4500 automated hematology analyzer offers fast reliable test results of 18-parameter plus 3-histograms, valuable for effective diagnosis....
Medicine Products: