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Sanofi Pasteur Initiates Phase II Trial of Cell Culture-Based Seasonal Influenza Vaccine
Date:11/7/2007

k groups (elderly, people with chronic conditions/illness). Although difficult to assess, these annual epidemics are thought to result in between three and five million cases of severe illness and between 300 000 and 500 000 deaths every year around the world(1). Most deaths currently associated with influenza in industrialized countries occur among the elderly over 65 years of age.

Reference:

1. http://www.who.int/vaccine_research/diseases/ari/en/print.html

About Lonza Group

Lonza Biologics plc, is a biotechnology contract manufacturer and biologics service provider, which is a business sector of the Lonza Group, a chemical and biotechnology company driven by the life sciences. Lonza is headquartered in Basel, Switzerland, and is listed on the SWX Swiss Exchange. In 2006, Lonza had sales of CHF 2.91 billion. Further information can be found at http://www.lonza.com.

About Crucell

Crucell N.V. is a Dutch biotechnology company (Euronext, Nasdaq: CRXL; Swiss Exchange: CRX) focused on research, development and worldwide marketing of vaccines and antibodies that prevent and treat infectious diseases. Crucell's vaccines are sold in public and private markets worldwide. The company licenses its PER.C6(R) production technology and other technologies to the biopharmaceutical industry. Crucell is headquartered in Leiden (The Netherlands) and employs over a 1000 people. For more information, please visit http://www.crucell.com.

About sanofi-aventis

Sanofi-aventis, a leading global pharmaceutical company, discovers, develops and distributes therapeutic solutions to improve the lives of everyone. Sanofi-aventis is listed in Paris (EURONEXT: SAN) and in New York (NYSE:

SOURCE Sanofi Pasteur
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