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Sanofi Pasteur Global Dengue Vaccine Clinical Program Expanded in Latin America
Date:12/9/2009

MEXICO CITY, December 9 /PRNewswire-FirstCall/ -- Sanofi Pasteur, the vaccines division of the sanofi-aventis Group (EURONEXT: SAN and SNY), announced today the expansion of its dengue vaccine clinical program in Latin America with a new multicenter study in children and adolescent in Mexico, Colombia, Honduras and Puerto Rico. This new multicenter study complements an earlier study in Mexico and an ongoing study in Peru.

These studies are aimed at advancing the development of a novel vaccine for the prevention of dengue infections in Latin America. Currently, there is no specific treatment available against dengue fever, which is the most widespread tropical disease after malaria.

"Latin America was considered almost free of dengue in the 1960s. Since then, urbanization and travel have contributed to the fast re-emergence of the disease. Today, dengue disease is a severe public health issue throughout Latin America," said Dr. Roberto Tapia-Conyer, Director General at Carso Health Institute. "So far, controlling the mosquitoes that transmit dengue didn't stop this trend. A safe and effective vaccine would be most welcome to prevent dengue epidemics in the region."

Dengue in Latin America: a growing burden

Nineteen Latin American countries were certified as dengue free between 1952 and 1965. The first reappearance of dengue fever was recorded in 1968, and by 2007 the disease had once more taken hold in all those countries [1]. In 2008 and 2009, severe dengue epidemics have been reported in Mexico, Paraguay, Brazil, Bolivia and Argentina. Many factors have contributed to the re-emergence and dramatic increase in dengue fever including urbanization and increased travel which facilitates dissemination of dengue viruses and the circulation of all four dengue serotypes in the region.

"Fighting dengue is of the utmost public health importance: We must remain o
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SOURCE Sanofi Pasteur
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