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Sanofi Enters Into Research Collaboration with Weill Cornell Medical College to Discover New Treatments for Tuberculosis
Date:6/29/2011

PARIS, June 29, 2011 /PRNewswire/ -- Sanofi (EURONEXT: SAN and NYSE: SNY) announced today that it entered into a research collaboration with Weill Cornell Medical College to develop new anti-infectives that aim to shorten the course of treatment of tuberculosis (TB) and provide effective therapies against drug-susceptible and drug-resistant strains of TB.

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Under the terms of the collaboration, Sanofi will provide 80,000 chemical compounds to Dr. Carl Nathan's laboratory at Weill Cornell, where the compounds will be screened to assess their ability to inhibit growth of Mycobacterium tuberculosis. Weill Cornell has secured funding for the screening activities conducted by Dr. Nathan's team from the Bill & Melinda Gates Foundation. Sanofi and Weill Cornell will jointly determine if any compounds screened through the collaboration should be brought forward for optimization and further development.

"Since discovering rifampicin in the early 1960s, Sanofi has continued to pursue new therapeutic approaches to combat TB, including new vaccines and drug candidates with new mechanisms of action," said Elias Zerhouni, President, Global R&D at Sanofi. "This research collaboration with Weill Cornell will enable us to explore the potential of our existing compound library and pool the extensive knowledge of Dr. Nathan and his colleagues with Sanofi's drug development expertise to benefit TB patients worldwide in continuation of our long standing commitment to global health."

Every year, more than 1.7 million people worldwide die from TB. Today's TB drugs are more than 40 years old and must be taken for six to nine months for drug-sensitive disease and up to 24 months for drug-resistant disease. Long, demanding treatment schedules prove too much for many patients and the resulting
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