Navigation Links
Sanofi Aventis: Study Shows Otamixaban Substantially Reduced Complications of Invasive Management of Acute Coronary Syndromes
Date:8/31/2009

PARIS, August 31 /PRNewswire-FirstCall/ --

- SEPIA-ACS Multiple-Dose Phase II Results Showing 27- 42% Risk Reduction in ACS Complications Presented in Plenary Session of European Society of Cardiology Congress and Published in The Lancet -

Sanofi-aventis (EURONEXT: SAN and NYSE: SNY) announced today that the investigational anti-Xa intravenous anticoagulant otamixaban reduced by 27 to 42 percent the odds of the composite primary endpoint of death, myocardial infarction, urgent revascularization or rescue GPIIb/IIIa use in 4 out of the 5 otamixaban tested doses, versus standard UFH/eptifibatide combination in [non-ST] ACS patients suitable for invasive strategy. The results of the SEPIA-ACS1/ TIMI-42 were presented today at the plenary session of the Annual European Society of Cardiology congress in Barcelona and simultaneously published online in The Lancet.

Otamixaban is a first in class, rapid onset antithrombotic compound, acting as a direct selective inhibitor of factor Xa. Otamixaban is originating from sanofi-aventis world-class thrombosis research portfolio and is currently in phase IIb clinical development phase.

"The data show that intermediate dosages of otamixaban may offer substantial reduction in major coronary complications in patients presenting with acute coronary syndrome, with bleeding rate comparable to current therapy," said Dr Marc Sabatine, MD, MPH, an Investigator in the TIMI Study Group and a cardiologist at Brigham and Women's Hospital, Harvard Medical School. "This research is addressing an important medical need, by potentially significantly improving outcomes of ACS patients undergoing PCI while simplifying the treatment pattern of the acute management phase of the disease," he added.

The double-blind phase
'/>"/>

SOURCE Sanofi-aventis
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Sanofi Pasteur Submits Supplemental Application for A(H1N1) Pandemic Vaccine to U.S. FDA
2. Sanofi-aventis Stands Behind the Safety of Lantus(R)
3. Sanofi Pasteur Dengue Vaccine Enters Pediatric Efficacy Clinical Study
4. Sanofi Pasteur Starts a Phase II Study of a Vaccine Against Clostridium Difficile
5. Sanofi Aventis: People With Type 2 Diabetes Treated With LANTUS(R) and APIDRA(R) Achieved Greater Reductions in A1C Than Those Treated With Pre-mixed Insulin
6. Insulin Analogues From Novo Nordisk, Eli Lilly and Sanofi-Aventis Will Drive Growth in the Type 1 Diabetes Drug Market
7. Sanofi Pasteur Shipping First Doses of Influenza Vaccine for the 2008-2009 Season in the US
8. Sanofi Pasteur to Donate 60 Million Doses of H5N1 Vaccine to WHO Over 3 Years for its Influenza Vaccine Global Stockpile
9. Sanofi Pasteur Initiates Phase II Trial of Cell Culture-Based Seasonal Influenza Vaccine
10. Sanofi Pasteur Receives FDA Approval of Meningococcal Vaccine for Children
11. Vical Licensee Sanofi-aventis Initiates Phase 3 Trial to Reduce Amputations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... Mich. , Aug. 22, 2014  Diplomat, ... selected as one of two winners in the ... Specialty Pharmacy Solutions, LLC. The results of the ... of Specialty Pharmacy News. Diplomat ... Diplomat University Education & Training program. Through Diplomat ...
(Date:8/22/2014)... /CNW/ - On Aug. 20, at its annual meeting ... Association (CMA) voted on and approved a delegate resolution ... cannabis. Bedrocan Cannabis Corp., a leading Canadian licensed producer ... The CMA is quite right to point ... any plant material, including medicinal cannabis. While some patients, ...
(Date:8/22/2014)... , Aug. 22, 2014  Dr. Mark Rasak ... the Diamond Lifetime Achievement Award in the field of ... of Cardiovascular Clinical Associates. Dr. Rasak has ... all major aspects of the business; overseeing the daily ... primary coronary intervention. In addition, he is an honored ...
Breaking Medicine Technology:Diplomat honored as a Top Innovator by Specialty Pharmacy News 2Bedrocan Canada Statement Regarding Canadian Medical Association Motion on Smoking Marijuana 2Dr. Mark Rasak, MD is recognized by Continental Who's Who with the Diamond Lifetime Achievement Award 2
(Date:8/22/2014)... San Jose, CA (PRWEB) August 22, 2014 ... are now offering a new teeth whitening technique. Air ... during regular cleaning appointments. , Dark teeth can be ... into two categories: external stains and internal stains. External ... Internal stains can be caused by certain medications, such ...
(Date:8/22/2014)... found that targeted automated alerts in electronic health ... patients with urinary catheters. In addition, when the ... of improvement dramatically increased. , The alerts help ... in the first place and then alert them ... not been removed within a recommended time period. ...
(Date:8/22/2014)... August 22, 2014 Natural Clear Vision ... to restore his own vision from legally blind to perfect ... an investigative review. , “There is a huge portion ... for everyday function, and most people just think that’s the ... eye surgery that can be pretty risky at times,” reports ...
(Date:8/22/2014)... found in the circulating free tumor DNA (ctDNA) from ... patients correlates well with the EGFR mutations from patient-matched ... therapy is approved for EGFR activating mutation positive patients ... status is with DNA derived directly from tumor tissue, ... abundant and less invasive source of tumor DNA may ...
(Date:8/22/2014)... (PRWEB) August 22, 2014 Testosterone ... filed in U.S. courts on behalf of men ... their use of prescription low testosterone therapies, Bernstein ... new claim was filed against Pfizer Inc. on ... suffered life-threatening heart issues due to his use ...
Breaking Medicine News(10 mins):Health News:Japantown Dental Introduces Air Polishing 2Health News:Penn study: Electronic alerts significantly reduce catheter-associated urinary tract infections 2Health News:Penn study: Electronic alerts significantly reduce catheter-associated urinary tract infections 3Health News:Natural Clear Vision: Review Exposes Kevin Richardson’s Program for Restoring Vision Naturally 2Health News:High concordance between EGFR mutations from circulating-free tumor DNA and tumor tissue in non-small cell lung cancer 2Health News:Testosterone Treatment Lawsuit News: New Filing Alleges Depo-Testosterone Caused Life-Threatening Heart Problems, Bernstein Liebhard LLP reports. 2Health News:Testosterone Treatment Lawsuit News: New Filing Alleges Depo-Testosterone Caused Life-Threatening Heart Problems, Bernstein Liebhard LLP reports. 3Health News:Testosterone Treatment Lawsuit News: New Filing Alleges Depo-Testosterone Caused Life-Threatening Heart Problems, Bernstein Liebhard LLP reports. 4
... than those that are not. A new study says ... as celiac disease”// ,CD, also known as celiac ... to result from the activation of both a cell-mediated ... glutens (prolamins and glutenins) found in wheat, barley, rye, ...
... Chemistry and Industry magazine says that tropical plants imported ... dengue and other related illnesses. // ,The Asian ... and this species was detected in the Netherlands leading ... These mosquitoes were detected in imported bamboo in a ...
... dengue fever vaccine full of promise is being tried in ... the GlaxoSmithKline vaccine //have been completed in the US and ... finished by the end of next year, Dr. Hans L. ... interest in making the vaccine available fast, given that this ...
... with anti-TNF agents (etanercept) and chemotherapy drug methotrexate ... treatment of Rheumatoid Arthritis.// Furthermore, the progression of ... over three quarters of patients. The chronic nature ... for prevention of long-term joint damage in addition ...
... Aurobindo Pharma Ltd has announced that U.S. Food ... capsules USP 250 mg & 500 mg.// ... of bacterial infections such as bronchitis, tonsillitis, ear ... has achieved another major milestone by obtaining the ...
... conducted on nearly 50 nursery school children has revealed ... it on to their children as well, //resulting in ... were considerably higher amongst the group of children studied. ... children were greater than twice the normal levels in ...
Cached Medicine News:Health News:Breastfeeding: A Boon For Cealiac Disease 2Health News:Combination Therapy With ENBREL And Methotrexate Found Effective In RA Treatment 2Health News:Children’s Stress Levels Directly Related To Maternal Job Satisfaction 2
... Slit Lamp features easy-to-use controls to help ... to a halogen bulb that gives up ... with powers of 10X and 16X, the ... accepts commercially available C-mount cameras, allowing physicians ...
... uses state-of-the-art waveform analysis and ... a 65MHz rate to obtain ... and averages nine measurements and ... fits comfortably into the hand ...
Perfect for loading small volume samples onto agarose and polyacrylamide gels....
1000 L, Bulk Recommended for 500 and 1000 L pipettes...
Medicine Products: