Navigation Links
Sangart, Inc. Initiates Phase IIa Study of Oxygen Therapeutic Agent MP4OX in Severe Trauma Patients With Hemorrhagic Shock
Date:12/9/2009

SAN DIEGO, Dec. 9 /PRNewswire/ -- Sangart, Inc., a global biopharmaceutical company dedicated to developing life-saving medicines specifically designed to enhance the perfusion and oxygenation of ischemic (oxygen deprived) tissues through targeted oxygen delivery, today announced the initiation of a dose-finding study designed to evaluate the safety and efficacy of MP4OX treatment plus standard of care in severely injured trauma patients with lactic acidosis due to hemorrhagic shock. MP4OX is a novel oxygen therapeutic agent that is designed to provide rapid oxygen delivery to ischemic tissues.

"Pre-clinical studies suggest that MP4OX has the potential to improve outcomes after major trauma. When a lot of blood has been lost and patients are in shock, MP4OX may increase the delivery of oxygen to the body and therefore prevent organs from failing," said Karim Brohi, Professor of Trauma Sciences at Barts and the London School of Medicine & Dentistry and lead study investigator. "The initiation of this clinical trial is an important step in finding a treatment that can improve patient outcomes after major trauma."

The clinical trial will be a multi-center, randomized, double-blind, controlled study that will enroll up to 75 patients who have suffered hemorrhagic shock with lactic acidosis across approximately 12 trial sites in Europe and South Africa. The primary objective of the study is to measure reduction in lactate levels after infusion of MP4OX. Acute traumatic injury, including both blunt and penetrating trauma is often associated with severe bleeding which can lead to hemorrhagic shock. During shock, inadequate perfusion of critical organs can lead to insufficient oxygenation of tissues, which can be detected by an increase in lactate levels.

"The initiation of this study is another key milestone for Sangart as we continue to develop medicines designed to enhance the delivery of oxygen to tissues and organ
'/>"/>

SOURCE Sangart, Inc.
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine technology :

1. Sangart, Inc. Initiates Dosing in Phase II Study of Hemospan(R) in Chronic Critical Limb Ischemia
2. Carrington Subsidiary DelSite Initiates Critical Toxicology Studies of Its Nasal Powder Bird Flu Vaccine
3. Romark Initiates Clinical Trial of Alinia(R) for Chronic Hepatitis C in the United States
4. Millennium Initiates Clinical Trial to EVOLVE the Treatment of Patients with Newly Diagnosed Multiple Myeloma
5. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
6. MedImmune Initiates Phase 2a Multi-Dose Study in Patients with Asthma
7. Genta Initiates Phase 3 AGENDA Trial of Genasense(R) for Patients with Advanced Melanoma
8. Nuvelo Re-Initiates SONOMA-3 Trial of Alfimeprase in Patients With Catheter Occlusion
9. TorreyPines Therapeutics Initiates a Phase I Multiple Dose Clinical Trial of Tezampanel
10. Prolexys Pharmaceuticals Initiates Phase 1 Study
11. Isis Initiates Phase 1 Study of ISIS 325568 Targeting Glucagon Receptor to Treat Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... 22, 2013 Z-Medica, a leading developer and ... the first-ever line of products designed to meet the ... QuikClot ® EMS 4x4 Dressing, QuikClot ® ... Rolled Gauze™, all custom-designed to help responders stop bleeding ... transported to a hospital or trauma center. The line ...
(Date:5/22/2013)... MEDIFIRST SOLUTIONS, INC. (OTCQB: MFST) would like ... recent company developments. As Medifirst continues to expand its ... shareholders. Integrating social media into its investor relations strategy, ... post updates on Twitter.  The Facebook homepage is Medifirst ... Says CEO Bruce J. Schoengood ...
(Date:5/22/2013)... 22, 2013  Flagship Ventures, a leading venture ... and sustainability, today announced the appointment of ... Partner. In this role, Mr. Bancel will provide ... In addition to working closely with companies ... as President and Chief Executive Officer of Moderna ...
Breaking Medicine Technology:Z-Medica Launches New Line of Hemostatic Agents for use in Emergency Medical Services 2Medifirst Solutions, Inc. Announces Update To Shareholders 2Life Science Industry Veteran Stephane Bancel Joins Flagship Ventures 2Life Science Industry Veteran Stephane Bancel Joins Flagship Ventures 3
(Date:5/22/2013)... -- In the aftermath of this week,s deadly tornado, many ... children and relatives, but also their pets. Finding ... and relocating to temporary housing can be stressful, but experts ... on how to ease that transition. One smart step: ... can be used to help identify any animals displaced during ...
(Date:5/22/2013)... - A University of Illinois researcher says that the ... be to encourage more people to participate in the ... According to Craig Gundersen, SNAP, formerly known as the ... program and with some additional improvements could be even ... Gundersen is a U of I professor of agricultural ...
(Date:5/22/2013)... a father,s depression have on his young son or daughter? ... their marriage, their children benefit, said a University of Illinois ... they need to be able to attend to the child,s ... abilities, and notice whether he is getting frustrated or needs ... McElwain, a U of I professor of human development. , ...
(Date:5/22/2013)... provides neurobiological evidence for dysfunction in the neural ... which may have implications for the risk relationship ... consistently identified as a risk factor for depression," ... professor of psychiatry at the University of Pittsburgh ... underlying emotion regulation may be involved in the ...
(Date:5/22/2013)... The newest member of TeethWhiteningforFree.com is Dr. James ... graduate, Dr. Sanderson provides professional dental care to Hoover ... extends complimentary teeth whitening to his patients who visit ... Only a dental professional can decide if the patient’s ... , Teeth whitening is an easy way to ...
Breaking Medicine News(10 mins):Health News:Simple Steps Can Protect Pets in Weather Disasters 2Health News:Alleviating hunger in the US -- researcher says, it's a SNAP 2Health News:Alleviating hunger in the US -- researcher says, it's a SNAP 3Health News:Good marriage can buffer effects of dad's depression on young children 2Health News:Study shows that insomnia may cause dysfunction in emotional brain circuitry 2Health News:Dr. James Sanderson, Jr. Of SanDentistry in Hoover, Alabama Joins the TeethWhiteningforFree.com Family 2
... or MRSA, a type of bacteria resistant to treatment, is ... direct contact and can spark off skin infections in normal ... to be dormant in nearly 2.3 million Americans with no ... crucial to identify the carriers of the illness and treat ...
... Sunday in Dhaka, which is being attended by health ministers ... discuss ways to improve// collaboration to develop health care services ... by the Bangladeshi Prime minister; Begum Khaleda Zia. She appealed ... to everyone in this region without delay. ,"We ...
... by the Cleveland Clinic for failing to disclose the ... by him.// Yadav is the creator of AngioGard, a ... procedures. Yadav was affiliated to the Cleveland Clinic since ... Foundation. ,A statement released by the clinic ...
... the University of Michigan Depression Center find that a ... not getting appropriate treatment for it.// Even pregnant women ... study added. Reporting in General Hospital Psychiatry, the researchers ... the correct one. Treatment is important since prenatal and ...
... about a real life New York Nightclub. The star ... the movie on the club,// which treats people like celebrities ... contactmusic.com, Partybuddys was founded by James King and Jason Roefaro, ... pay hefty fees. The hosts help them get into VIP ...
... the August issue of the journal Neuron, published by ... de Araujo and colleagues,// have mapped the activity of ... multiple feeding-related brain areas. Until now studies of ... only fragmentary measuring brain regions only at specific times ...
Cached Medicine News:Health News:Indo-American Doctor Fired By Cleveland Clinic 2Health News:Indo-American Doctor Fired By Cleveland Clinic 3Health News:Indo-American Doctor Fired By Cleveland Clinic 4Health News:Depression In Pregnant Women Not Being Treated 2Health News:Depression In Pregnant Women Not Being Treated 3Health News:Depression In Pregnant Women Not Being Treated 4Health News:Hunger Mapping 2
... German Craftsmanship have produced ... in the world. Ocutek ... to you! Only holders ... certificate, which requires and ...
... Centuries of German Craftsmanship ... surgical instrumentation in the ... them available to you! ... coveted Meisterbrief certificate, which ...
... German Craftsmanship have produced ... in the world. Ocutek ... to you! Only holders ... certificate, which requires and ...
... of German Craftsmanship have ... instrumentation in the world. ... available to you! Only ... Meisterbrief certificate, which requires ...
Medicine Products: