Navigation Links
Sangamo BioSciences Presents Clinical Data From Key SB-728-T HIV Studies: Proof Of Concept For Ongoing Sustained Functional Control Of HIV Viral Load; Cytoxan Preconditioning Successfully Enhances Engraftment
Date:12/6/2013

RICHMOND, Calif., Dec. 6, 2013 /PRNewswire/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today the presentation of data from all dose cohorts in the Company's ongoing clinical trials (SB-728-1101 and SB-728-902 Cohort 5) of SB-728-T, which is being developed for the functional control of HIV/AIDS. The data are being presented at the Sixth International Workshop on HIV Persistence during Therapy, considered to be the reference workshop on HIV reservoirs and eradication strategies, which is being held in Miami, FL, December 3-6 2013.

(Logo: http://photos.prnewswire.com/prnh/20130102/SF35903LOGO)

"The results announced today represent a major milestone," stated Geoff Nichol, M.B., Ch.B., Sangamo's executive vice president of research and development. "We have succeeded in achieving sustained control of HIV with SB-728-T in CCR5 delta-32 heterozygotes, and we have shown that we can safely use Cytoxan to potentially achieve threshold levels of engraftment for all patients with HIV. Collectively, data from our clinical studies suggest that protection of CD4 T-cells by ZFN mediated CCR5 disruption may provide helper function to CD8 cells enabling the immune system to mount an anti-HIV response that can also erode the HIV reservoir.  The reservoir is a compartment of the HIV-infected immune system that is not addressed by antiretroviral medication and its depletion is key to the goal of complete eradication of HIV infection."

Sangamo's Phase 1 data suggested that if a threshold level of engraftment of SB-728-T was achieved, specifically of CD4 cells fully protected from HIV entry by zinc finger nuclease (ZFN)-mediated modification of both CCR5 genes (biallelic modification), then functional contr
'/>"/>

SOURCE Sangamo BioSciences, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. Sangamo BioSciences Reports Second Quarter 2012 Financial Results
2. Sangamo BioSciences to Webcast Analyst Briefing on Thursday, December 6, 2012
3. Sangamo BioSciences Reports Fourth Quarter And Full Year 2012 Financial Results
4. Sangamo BioSciences Announces Presentation At 33rd Annual Cowen And Company Health Care Conference
5. Sangamo BioSciences Announces Presentation At The Barclays Global Healthcare Conference
6. Sangamo BioSciences Announces First Quarter 2013 Conference Call and Webcast
7. Sangamo BioSciences Reports First Quarter 2013 Financial Results
8. Sangamo BioSciences Announces Second Quarter 2013 Conference Call And Webcast
9. Sangamo BioSciences Announces Publication of First Demonstration of Inactivation of Extra Chromosome Responsible for Down Syndrome
10. Sangamo BioSciences Reports Second Quarter 2013 Financial Results
11. Sangamo BioSciences Announces Notice Of Allowance For New Patent Application Covering Genome Modification Technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... Sept. 30, 2014  The orthopedic specialists at Midwest ... 6 orthopedic group by US News & World Report, ... series of free, public seminars to discuss partial and ... world come to see the knee physicians at Midwest ... available at Munster Specialty Surgery Center. ...
(Date:9/30/2014)... In 2011, approximately 5.1 million people in ... pain relievers (e.g. opioids). 1 Clinical treatments for ... the use of buprenorphine, buprenorphine/naloxone, naltrexone or methadone. The ... developing and improving care management programs, according to ... Therapeutics LLC (Prime). Cost trends ...
(Date:9/30/2014)... Sept. 30, 2014 Headquartered in ... a diversified company comprised of several specialized partners focused ... and the proven expertise of its team of professionals ... WholeHealth Products, line of more than 10 professional diagnostic ... its more than 8 retail consumer tests is proud ...
Breaking Medicine Technology:"Knee Pain Solutions for Active Adults" Complimentary Seminars Open to the Public 2Studies show cost and use of opioid dependence treatment are increasing, spurring the need for care management programs 2Studies show cost and use of opioid dependence treatment are increasing, spurring the need for care management programs 3WholeHealth Products Announces The Discovery Of The "Autism And Fragile X" Microwell And Rapid Diagnostic Test 2
... , , THOUSAND OAKS, Calif., Jan. 7 Amgen ... JP Morgan Global Healthcare Conference at 8:00 a.m. Pacific Time ... in San Francisco, Calif. Amgen Chairman and CEO Kevin ... presentation will be available over the Internet and can be ...
... , , TUCSON, Ariz., Jan. 7 ... Fletcher McCusker, Chairman and Chief Executive Officer, is scheduled to present ... First 2010 Micro Cap Conference on Monday, January 11, 2010 at ... is scheduled for 1:50 p.m. ET. , On Thursday, ...
Cached Medicine Technology:Amgen to Present at the 28th Annual JP Morgan Healthcare Conference 2Providence Service Corporation to Present at the Sidoti & Company, LLC Micro Cap Conference on Monday, January 11th and at the CJS Securities 'New Ideas for the New Year' Conference on Thursday, January 14th 2
(Date:9/30/2014)... 30, 2014 Dynamic health trends, ... growth in the Bread Production industry over the ... to moderate their consumption of a variety of ... varieties shrunk the market for white loaf bread ... responded by introducing more nutritious products to attract ...
(Date:9/30/2014)... been awarded a three-year $1.7 million grant from ... new imaging technologies and data analysis techniques that ... of neurons in the brain interact to process ... the precise interactions between millions of nerve cells ... alterations in these interactions that may be responsible ...
(Date:9/30/2014)... The American Diabetes Association ... curb their sweet tooth, but the most recent research, ... suggests that zero-calorie sweeteners may actually be linked to ... The Weizmann Institute of Science in Israel recently ... mice, the mice developed glucose intolerance. They then analyzed ...
(Date:9/30/2014)... Regenerative Medicine Solutions (RMS) is set to open ... RMS welcomes the launch of an entirely new facility, ... new treatment center for the Lung Institute. , ... Nashville, the hope is to bring awareness to those ... undiagnosed. With Nashville being a hub for medical technology, ...
(Date:9/30/2014)... should cover low-dose computed tomography lung cancer screening for ... of more than 60 patient and medical groups says. ... the Society of Thoracic Surgeons, the American College of ... of Clinical Oncology, made its point in a letter ... Medicaid Services (CMS). Such screening reduces lung cancer ...
Breaking Medicine News(10 mins):Health News:Bread Production in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Bread Production in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:UMD receives inaugural BRAIN Initiative Award 2Health News:Artificial Sweeteners May be Linked to Greater Diabetes Risk 2Health News:Regenerative Medicine Solutions Expanding 2Health News:Groups Call for Medicare Coverage of Lung Cancer Screening 2
... wonder food. With a plethora of medicinal properties it is ... ward off evil spirits, such as vampires. Now scientists are ... may help ward off carcinogens produced by meat cooked at ... eggs at high temperatures releases a chemical called PhIP, a ...
... servings a day of soy protein (found in soy foods ... cholesterol levels by nine percent. // , ,However, the ... to preserve the active protein. Because of this, soy-supplemented muffins, ... due to the high temperature used to prepare these foods. ...
... study finds that regularly eating broccoli sprouts may help prevent ... is known to cause gastritis and is believed to be ... ,The study, conducted by a Japanese team, found that ... day resulted in patients with H. pylori infection experiencing a ...
... compound found in grapes and red wine, lowers ... the telltale senile plaques of Alzheimer's disease. // ... potential neuroprotective activities. Resveratrol is an antioxidant, a ... their health benefits. It is a natural polyphenol ...
... Wan Lian Chua, Psychiatrist, Bradford District Care Trust had ... not given any effective improvement in their condition. //The ... of estrogen therapy for treatment of Schizophrenia. Researchers conclude ... in treating patients before it is tested in large ...
... this year’s strain of Bird flu virus which has been ... poultry and birds in Mongolia under the directive of World ... Conservation Society (WCS) Veterinarian to prepare the vaccine which would ... of veterinarian is spear headed by Drs. William Karesh and ...
Cached Medicine News:Health News:A Boon For Gastritis Patients In The Form Of Broccoli 2
... 5mm AEM Laparoscopic Instruments incorporate a layered ... are shielded and monitored to prevent stray ... instrument caused by insulation failure or capacitive ... protective shield built into all AEM Instruments ...
... The 5mm AEM Laparoscopic Instruments incorporate ... AEM Instruments are shielded and monitored to ... of the instrument caused by insulation failure ... risk. The protective shield built into all ...
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
... Enhanced features including aspiration holes ... in laparoscopic procedures requiring precise dissection ... and increased suction demands. ,Flexible ... retractable and nonretractable electrodes and multiple ...
Medicine Products: