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Sanaria's Malaria Vaccine Yields Unprecedented Protection In Phase 1 Clinical Trial
Date:8/8/2013

ROCKVILLE, Md., Aug. 8, 2013 /PRNewswire/ -- Results of a phase I clinical trial of the Sanaria® PfSPZ Vaccine to combat malaria, published today in the online issue of Science magazine, show that the vaccine provided complete protection against malaria in subjects who were exposed to Plasmodium falciparum parasites. Plasmodium falciparum is the malaria parasite that causes more than 600,000 deaths annually.

"While we're still in the early stages of testing, we believe this vaccine will be used to eliminate malaria," said Stephen L. Hoffman, CEO of Sanaria. "It's reasonable to suggest that within three-to-five years, a safe, reliable vaccine could be a commercial reality and provide medical benefit to a huge population."

The current trial was primarily funded by the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) with additional support from the Naval Medical Research Center and Sanaria. Sanaria has also received research support and funding from multiple other institutions in the United States, Europe, and Africa during the past decade and will continue its fund-raising efforts to expand its research and clinical programs.

"Scientists have struggled to produce an effective malaria vaccine for more than three decades," Hoffman said. "These results show that we have a safe, successful, injectable vaccine that has the potential to save millions of lives."

Princeton professor, former president of Merck Vaccines, and Sanaria board member, Dr. Adel Mahmoud concluded that, "This whole-parasite vaccine, produced in a form that can be easily administered, is now shown to stimulate immunity with a clear dose response leading to full protection. Not only was the vaccine fully protective, it wa
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SOURCE Sanaria
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