Navigation Links
Same Problems in "New" Research on Autism and Vaccines
Date:4/8/2013

WASHINGTON, April 8, 2013 /PRNewswire-USNewswire/ -- A new book chapter on statistical methods in Recent Advances in Autism Spectrum Disorders by University of Northern Iowa researchers, DeSoto and Hitlan[1] documents major methodological flaws in the data set said to disprove the link between Thimerosal-preserved vaccines and autism by Price, et al.[2]   More recently DeStefano et al. [3] used the same data set while attempting to disprove a link between the number of vaccines and autism.

"Both researchers tested whether any increased risk of autism was associated with increased exposures via vaccination.  To do so, they must compare different levels of exposure.  They failed to do so when they matched cases to controls on birth-year and HMO.  Birth-year, by itself, defines exposure level and HMOs further ensures similarity guaranteeing cases and controls were nearly identical on the exposure," said lead author Dr. Catherine DeSoto .  "This is a design flaw called overmatching, it forces cases and controls to be artificially similar and renders the results invalid."

The number, type and timing of vaccines US children receive is a function of birth-year. Formulations purchased and administered would be the same within a given HMO.    

"By matching on birth year and HMO, they eliminated the variability right from the start," said Sallie Bernard , President of SafeMinds.  "Here's a perfect example of the cascading impact from problem data analysis. The same statistical flaws in Price's 2010 research resurface in De Stefano's 2013 research."

"Once again, media reported exactly what CDC released last week without critically reviewing the information," said Eric Uram , Executive Director at SafeMinds. 

Prior to approving Price et al. research, an appointed panel reviewed the study methodology raising design concerns.  Ultimately, the Centers for Disease Control and Prevention (CDC) National Immunization Program dismissed them.  In 2010, SafeMinds challenged the Price et al., article's claims by highlighting flaws related to errors in the design. [4]  "Peer reviewers should reach agreement," concluded Bernard. "With Price, final approval processes were tipped to accept flawed methods."

SafeMinds maintains listings on peer reviewed research performed by independent scientists documenting neural risks associated with thimerosal and vaccination.  Reporters are encouraged to review and then contact the doctors and scientists doing high-quality work on the issues.[5]

[1] http://cdn.intechopen.com/pdfs/41866/InTech-Vaccine_safety_study_as_an_interesting_case_of_over_matching_.pdf

[2] http://www.pediatricsdigest.mobi/content/126/4/656.full

[3] http://www.jpeds.com/webfiles/images/journals/ympd/JPEDSDeStefano.pdf

[4] http://www.ageofautism.com/2010/09/safeminds-comments-on-pediatrics-study-on-thimerosal-and-vaccines.html

[5] http://www.safeminds.org/research/docs/Thimerosal%20Science%20Summary%20Dec%202012.pdf

 


'/>"/>
SOURCE SafeMinds
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Problems Plague Medicares Method for Measuring Payment Errors
2. Texas Medicaid Managed-Care Problems Gaining National Attention
3. Physician Details Problems with Medicare Approval Process for Power Wheelchairs
4. Problems With the Stryker Rejuvenate Hip System
5. The Hygenic Corporations Custom Rubber Solutions Solve Industry Problems
6. Only Podiatric Surgeon In S. Florida That Performs In-Office Ultrasound Imaging On Foot & Ankle Problems Saving Patients Over $1,000 In MRI Expenses & Extra Trip To Hospital
7. Promise and Problems Signal Mixed Year Ahead for Biopharmaceutical Industry, Says Pharmaceutical Executive Magazine
8. Orthopedic Practices Choose Medicalbillersandcoders.coms Orthopedic Billing Solutions for Their Cash Flow Problems!
9. FDA Cleared ChromaGen Lenses Are A Life-Changing Aid For People Struggling With Dyslexia And Other Reading Problems
10. Army Researcher Develops Potential Vaccine Carrier That May Give Stockpiling Efforts A Shot In The Arm
11. JDRF Announces Research Collaboration with Dexcom, Inc. to Develop "Smart Transmitter" Technology to Accelerate Artificial Pancreas Studies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... Research and Markets has announced the addition of ... report to their offering. ... kidney failure, it replaces the function of kidneys by removing ... thus the treatment helps to keep the patient body,s electrolytes ... Increasing number of ESRD patients & substantial healthcare expenditure ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 Roche ... received 510(k) clearance for its Elecsys BRAHMS PCT (procalcitonin) ... severe sepsis or septic shock. With this clearance, Roche ... provide a fully integrated solution for sepsis risk assessment ... associated with bacterial infection and PCT levels in blood ...
(Date:6/23/2016)... , June 23, 2016 Bracket , ... launch its next generation clinical outcomes platform, Bracket eCOA (SM) ... held on June 26 – 30, 2016 in ... first electronic Clinical Outcome Assessment product of its kind to ... #715. Bracket eCOA 6.0 is a flexible platform ...
Breaking Medicine Technology:
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now reveal their media ... Pro X," said Christina Austin - CEO of Pixel Film Studios. , ProSlice ... X users can now reveal the media of their split screens with growing ...
(Date:6/26/2016)... N.J. (PRWEB) , ... June 27, 2016 , ... Quality ... sources, yet in many ways they remain in the eye of the beholder, according ... (EBO), a publication of The American Journal of Managed Care. For the full issue, ...
(Date:6/26/2016)... Orion, Clarkston, Michigan (PRWEB) , ... June 26, ... ... with respect to fertility once they have been diagnosed with endometriosis. These women ... intercourse but they also require a comprehensive approach that can help for preservation ...
(Date:6/25/2016)... , ... June 25, 2016 , ... First Choice ... States, named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm ... Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article ... people are unfamiliar with. The article goes on to state that individuals are now ... of these less common operations such as calf and cheek reduction. The Los Angeles ...
Breaking Medicine News(10 mins):