Navigation Links
Same Problems in "New" Research on Autism and Vaccines
Date:4/8/2013

WASHINGTON, April 8, 2013 /PRNewswire-USNewswire/ -- A new book chapter on statistical methods in Recent Advances in Autism Spectrum Disorders by University of Northern Iowa researchers, DeSoto and Hitlan[1] documents major methodological flaws in the data set said to disprove the link between Thimerosal-preserved vaccines and autism by Price, et al.[2]   More recently DeStefano et al. [3] used the same data set while attempting to disprove a link between the number of vaccines and autism.

"Both researchers tested whether any increased risk of autism was associated with increased exposures via vaccination.  To do so, they must compare different levels of exposure.  They failed to do so when they matched cases to controls on birth-year and HMO.  Birth-year, by itself, defines exposure level and HMOs further ensures similarity guaranteeing cases and controls were nearly identical on the exposure," said lead author Dr. Catherine DeSoto .  "This is a design flaw called overmatching, it forces cases and controls to be artificially similar and renders the results invalid."

The number, type and timing of vaccines US children receive is a function of birth-year. Formulations purchased and administered would be the same within a given HMO.    

"By matching on birth year and HMO, they eliminated the variability right from the start," said Sallie Bernard , President of SafeMinds.  "Here's a perfect example of the cascading impact from problem data analysis. The same statistical flaws in Price's 2010 research resurface in De Stefano's 2013 research."

"Once again, media reported exactly what CDC released last week without critically reviewing the information," said Eric Uram , Executive Director at SafeMinds. 

Prior to approving Price et al. research, an appointed panel reviewed the study methodology raising design concerns.  Ultimately, the Centers for Disease Control and Prevention (CDC) National Immunization Program dismissed them.  In 2010, SafeMinds challenged the Price et al., article's claims by highlighting flaws related to errors in the design. [4]  "Peer reviewers should reach agreement," concluded Bernard. "With Price, final approval processes were tipped to accept flawed methods."

SafeMinds maintains listings on peer reviewed research performed by independent scientists documenting neural risks associated with thimerosal and vaccination.  Reporters are encouraged to review and then contact the doctors and scientists doing high-quality work on the issues.[5]

[1] http://cdn.intechopen.com/pdfs/41866/InTech-Vaccine_safety_study_as_an_interesting_case_of_over_matching_.pdf

[2] http://www.pediatricsdigest.mobi/content/126/4/656.full

[3] http://www.jpeds.com/webfiles/images/journals/ympd/JPEDSDeStefano.pdf

[4] http://www.ageofautism.com/2010/09/safeminds-comments-on-pediatrics-study-on-thimerosal-and-vaccines.html

[5] http://www.safeminds.org/research/docs/Thimerosal%20Science%20Summary%20Dec%202012.pdf

 


'/>"/>
SOURCE SafeMinds
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Problems Plague Medicares Method for Measuring Payment Errors
2. Texas Medicaid Managed-Care Problems Gaining National Attention
3. Physician Details Problems with Medicare Approval Process for Power Wheelchairs
4. Problems With the Stryker Rejuvenate Hip System
5. The Hygenic Corporations Custom Rubber Solutions Solve Industry Problems
6. Only Podiatric Surgeon In S. Florida That Performs In-Office Ultrasound Imaging On Foot & Ankle Problems Saving Patients Over $1,000 In MRI Expenses & Extra Trip To Hospital
7. Promise and Problems Signal Mixed Year Ahead for Biopharmaceutical Industry, Says Pharmaceutical Executive Magazine
8. Orthopedic Practices Choose Medicalbillersandcoders.coms Orthopedic Billing Solutions for Their Cash Flow Problems!
9. FDA Cleared ChromaGen Lenses Are A Life-Changing Aid For People Struggling With Dyslexia And Other Reading Problems
10. Army Researcher Develops Potential Vaccine Carrier That May Give Stockpiling Efforts A Shot In The Arm
11. JDRF Announces Research Collaboration with Dexcom, Inc. to Develop "Smart Transmitter" Technology to Accelerate Artificial Pancreas Studies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2017)... Inc. , a privately held, clinical-stage biopharmaceutical company developing immunogene therapeutics, ... Operating Officer, is scheduled to present a corporate overview at two ... BioPartnering & Investment Forum: Tuesday, March 28, 2017 at 3:00 PM ... ... Leaders in Biotech Industry – Friday, April 7, 2017 at 11:20 ...
(Date:3/27/2017)... -- Invivotek, LLC, a Genesis Biotechnology Group ® ... contract research organization (CRO), announced the completion of the ... research facility in Hamilton, New Jersey ... source to reduce costs and lessen the CRO facility,s ... Farm follows Invivotek,s recent expansion from a 19,712 square ...
(Date:3/24/2017)... 24, 2017 Abdominal Aortic Aneurysm Repair Devices Market was valued at ... registering a CAGR of 5.1% from 2016 to 2022. The endovascular stent graft system ... market during the study period. Continue Reading ... ... ...
Breaking Medicine Technology:
(Date:3/28/2017)... ... March 28, 2017 , ... Bacteria and fungi are probably not the first ingredients that come ... including the right microorganisms in your diet can actually improve health outcomes. And the good ... is the topic of a new peer-reviewed paper led by Maria Marco, ...
(Date:3/27/2017)... ... 2017 , ... Drs. Justin Kolnick, Kara Diamond, Randall Barton, Keith Hope and ... key role this treatment plays in protecting oral health, along with the benefits of ... who need a root canal in White Plains, NY or their second location in ...
(Date:3/27/2017)... ... March 27, 2017 , ... Buzzies parent company, The TouchPoint Solution’s CEO ... Runway Foundation and UBS’ Project Entrepreneur. Mayo will present her pitch about the lifestyle ... Project Entrepreneur’s second annual venture competition ignites bold ideas by providing women access to ...
(Date:3/27/2017)... ... March 27, 2017 , ... Osteitis ... A type of groin injury, it occurs when the muscles around the pelvis ... in and around the lower torso, as well as accompanying tenderness and weakness. ...
(Date:3/27/2017)... ... March 27, 2017 , ... The Association of ... professionals, will hold their first Northeast Regional AHVAP Meeting. For 2017, Dr. Hayes ... supply chain and value analysis professionals have a ‘seat at the table’ with ...
Breaking Medicine News(10 mins):