Navigation Links
Sahajanand Medical Technologies PAINT Trial Results Support Safety and Efficacy of the Infinnium and Supralimus Stents
Date:5/20/2008

Sahajanand Medical Technologies received positive results of nine month PAINT trials for Drug eluting stents, Infinnium and Supralimus. The results

unveiled during plenary session of EuroPCR 2008-Barcelona.

SURAT, India, May 20 /PRNewswire/ -- Sahajanand Medical Technologies Pvt. Ltd. (SMT), Surat, India, leading developer and manufacturer of drug-eluting stents, welcomed the positive results of the prospective, randomized nine months results of PAINT trial (PercutAneous INTervention with biodegradable- polymer based paclitaxel-eluting, sirolimus-eluting, or bare stents for the treatment of de novo coronary lesions).

The PAINT study was designed with a unique 3-arm format that allows the evaluation of three stents that only differ on the presence and/or type of drug (all stents have exactly the same material, strut thickness and platform design). This distinguishes the study from other comparative trials that aimed to assess the differences between Sirolimus and Paclitaxel (having different polymers and different platform).

The study hypothesizes that two novel formulations of stents with Paclitaxel (Infinnium) or Sirolimus (Supralimus), eluted in biodegradable polymers, are effective in reducing neointimal proliferation in comparison with bare metal stents.

The nine month results of PAINT, which were unveiled on Tuesday May 13th during the plenary session of EuroPCR 2008 -- Barcelona, Spain, demonstrated that in comparison with bare metal stents, both formulations of biodegradable-polymer Paclitaxel-eluting ( Infinnium ) and Sirolimus -eluting (Supralimus) stents are effective in reducing neointimal proliferation and the risk of repeat intervention at 270 days, without increasing the incidence of death or myocardial infarction.

Primary investigator, Dr Pedro Lemos of the Heart Institute (InCor) University of Sao Paulo Medical School, Brazil, commented that, "The design of PAINT (2:2:1 randomization of 280 patient with coronary de novo lesions) allowed to verify, in a single trial, the safety and efficacy of the two novel drug-eluting stent formulations." He added that "Another important point is that most previous comparative trials between Sirolimus & Paclitaxel used stents with two different platforms and polymers." "In the PAINT -- which used the same metal platform and coating for both active stents -- the effects of Sirolimus and Paclitaxel could be compared in a more direct way, since the only difference between the stents was the drug itself," he explains.

Dr Atul Abhyankar, Medical Director- Sahajanand's Medical Technologies, shared the enthusiasm. "The results of the PAINT trial truly add to the interventional community learning about DESs, it clearly proves that the biodegradable polymer used by SMT is effective and safe vehicle for DES and seems to work efficiently irrespective of the type of drugs. Both drugs (Paclitaxel & Sirolimus) were effective in reducing restenosis on the same vehicle and platform. So you have a luxury of choice of drug based on your own assessment."

Mr. Dhirajlal Kotadia, the Founder and Chairman of SMT; emphasized the company's commitment towards further intensifying its clinical research initiatives and continue to deliver evidence-based treatments to all deserving patients around the world.

The Infinnium - CE mark approved, stent system utilizes paclitaxel, which has been shown to reduce tissue proliferation in the coronary vessels following stent implantation, and is based upon the easily deliverable, thinnest strut (0.0032") Matrix coronary stent platform.

Sahajanand Medical Technologies is (http://www.smtpl.com/) a global developer & manufacturers of minimally invasive coronary stents, with one of the broadest product portfolios in the industry. (Infinnium , Infinicore, Supralimus , Supracore, Coronnium and Matrix).

Company Profile: Sahajanand Medical Technologies Pvt. Ltd. Established in the year 1998, company became the first Indigenous Stent Manufacturer in world to have two DES systems in its product portfolio. It is India's largest manufacturing company based on Evidence Based Implantable Medical Devices and Medical Equipments. The products are manufactured conforming to the international quality standards and are offered at the most competitive prices. The Company is ISO 9000 certified & also obtained CE certification for its advanced range of products. This gives assurance of company's quality consciousness. For more information log on to: http://www.smtpl.com

This press release was issued through 24-7PressRelease.com. For further information, visit http://www.24-7pressrelease.com.


'/>"/>
SOURCE Sahajanand Medical Technologies Pvt. Ltd.
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. Harvard Medical School-Partners HealthCare Center for Genetics and Genomics Successfully Completes Evaluation of AutoGenomics 2C9-VKORC1 Panel to Assess Warfarin Sensitivity
2. You May Have a Thyroid Problem and Not Know It - Particularly If Youre Over 60, Says a New Harvard Medical School Report
3. Harvard Medical School-Partners HealthCare Center for Genetics and Genomics Successfully Completes Evaluation of AutoGenomics 2C9-VKORC1 Panel to Assess Warfarin Sensitivity
4. Globus Medical Raises $110 Million in Series E Financing Round
5. Quark Pharmaceuticals Appoints New Chief Medical Officer
6. Boston University Biomedical Engineers Find Chink in Bacterias Armor
7. Rochester Medical Anti-Infection Foley Catheter Demonstrates Effectiveness in Randomized Trial
8. Rockwell Medical Technologies, Inc. Begins Patient Enrollment for its SFP Dose-Ranging Study
9. Flexible Medical Systems Raises $1.2M Seed Investment for Initial Human Trials
10. Cleveland Clinic Summits to Focus on Cardiovascular Medical Innovation
11. Rockwell Medical Technologies, Inc. Begins Dosing Patients for SFP Phase IIb Clinical Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... Feb. 8, 2016  Unilife Corporation ("Unilife" or "Company") (NASDAQ: ... injectable drug delivery systems, today announced that it will release ... December 31, 2015 after market close on February 9, 2016. ... call to discuss these financial results.    About ... --> About Unilife Corporation ...
(Date:2/8/2016)... NORTHBROOK, Ill. , Feb. 8, 2016  Astellas Pharma ... today announced the promotion of James Robinson as ... the company,s operations in North and South America ... president, Astellas Pharma US, representing the commercial organization in ... assumed in 2013. Masao Yoshida , who ...
(Date:2/8/2016)... Palatin Technologies, Inc. (NYSE MKT: PTN), ... for the treatment of diseases with significant unmet ... the United States Patent and Trademark Office (USPTO) ... Patent Application Serial Number 14/313,258 (the ,258 application).  ... female sexual dysfunction using the formulation and dose ...
Breaking Medicine Technology:
(Date:2/8/2016)... ... ... Remember the old saying “rub some dirt on it”? Perhaps you should try ... Clay” the health benefits of integrating clay into a daily diet are numerous, as ... motivational speaker, Perry A~ has since dedicated her life to learning about the benefits ...
(Date:2/8/2016)... , ... February 08, 2016 , ... ... wide variety of organizations. DocuSyst provides a cloud hosted environment for FileHold ... installations include integration with various 3rd party applications using the FileHold web services ...
(Date:2/8/2016)... ... 2016 , ... GrassrootsHealth published data from its D*action public ... in the GrassrootsHealth cohort with substantially higher vitamin D levels than a cohort ... states Carole Baggerly, Director of GrassrootsHealth, “the safety and benefits of vitamin ...
(Date:2/8/2016)... (PRWEB) , ... February 08, 2016 , ... TopConsumerReviews.com recently ... in Mole removal products. , Moles are derived from a cluster of melanin when ... all the wrong places and create a lifetime of embarrassment. Historically, mole removal ...
(Date:2/8/2016)... ... , ... Guruji Mahendra Kumar Trivedi is offering 3 days of accelerated personal ... birthday on February 10th. During this time, people can achieve better health, greater ... people from over 40 different countries as an “ordinary man with an extraordinary gift.” ...
Breaking Medicine News(10 mins):