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Sahajanand Medical Technologies PAINT Trial Results Support Safety and Efficacy of the Infinnium and Supralimus Stents
Date:5/20/2008

Sahajanand Medical Technologies received positive results of nine month PAINT trials for Drug eluting stents, Infinnium and Supralimus. The results

unveiled during plenary session of EuroPCR 2008-Barcelona.

SURAT, India, May 20 /PRNewswire/ -- Sahajanand Medical Technologies Pvt. Ltd. (SMT), Surat, India, leading developer and manufacturer of drug-eluting stents, welcomed the positive results of the prospective, randomized nine months results of PAINT trial (PercutAneous INTervention with biodegradable- polymer based paclitaxel-eluting, sirolimus-eluting, or bare stents for the treatment of de novo coronary lesions).

The PAINT study was designed with a unique 3-arm format that allows the evaluation of three stents that only differ on the presence and/or type of drug (all stents have exactly the same material, strut thickness and platform design). This distinguishes the study from other comparative trials that aimed to assess the differences between Sirolimus and Paclitaxel (having different polymers and different platform).

The study hypothesizes that two novel formulations of stents with Paclitaxel (Infinnium) or Sirolimus (Supralimus), eluted in biodegradable polymers, are effective in reducing neointimal proliferation in comparison with bare metal stents.

The nine month results of PAINT, which were unveiled on Tuesday May 13th during the plenary session of EuroPCR 2008 -- Barcelona, Spain, demonstrated that in comparison with bare metal stents, both formulations of biodegradable-polymer Paclitaxel-eluting ( Infinnium ) and Sirolimus -eluting (Supralimus) stents are effective in reducing neointimal proliferation and the risk of repeat intervention at 270 days, without increasing the incidence of death or myocardial infarction.

Primary investigator, Dr Pedro Lemos of the Heart Institute (InCor) University of Sao Paulo Medical School, Brazil, commented that, "The design of PAINT (2:2:1 randomization of 280 patient w
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SOURCE Sahajanand Medical Technologies Pvt. Ltd.
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