Navigation Links
Safinamide Phase III Study Results Presented at 2013 MDS Meeting
Date:6/18/2013

ence of treatment emergent abnormalities in laboratory results, ophthalmological examinations, vital signs and ECG was similar in all groups.

Analyses (On treatment, ANCOVA-LOCF) performed in the ITT population showed treatment with safinamide 50-100 mg/day significantly improved ON-Time without troublesome dyskinesia compared to placebo by 0.96 ± 0.21 hours (p<0.01) in the ITT. Significant benefits of safinamide 50-100 mg/day were also reported in OFF-time, Motor symptoms (UPDRS III), PDQ39, EQ-5D, clinical global impression of change and severity, and OFF-time post morning dose of levodopa.

The abstract presented at the MDS is available for download at: http://www.newron.com/ENG/Default.aspx?SEZ=5&PAG=122 and

http://http://www.zambonpharma.com

About safinamide

Safinamide, an alpha-aminoamide, is currently being developed by Newron as an add-on therapy to dopamine agonists or to levodopa in patients with early or mid- to late-stage Parkinson's disease (PD). It is believed to have both dopaminergic and non dopaminergic activities, including selective and reversible inhibition of monoamine oxidase B (MAO-B), activity-dependent sodium channel antagonism and inhibition of glutamate release in vitro.

About Newron Pharmaceuticals

Newron (SIX: NWRN) is a biopharmaceutical company focused on novel therapies for diseases of the Central Nervous System (CNS) and pain. The Company is headquartered in Bresso near Milan, Italy. Based on the phase III results of safinamide for treatment of Parkinson's disease, Newron is working to expedite the global filing of the compound, together with its partners. Zambon Group has the rights to commercialise safinamide globally, excluding Japan and other key Asian territories, and Meiji Seika'/>"/>

SOURCE Newron Pharmaceuticals
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Adamas Pharmaceuticals Presents Positive Phase 2/3 Results For ADS-5102 For The Treatment Of Levodopa-Induced Dyskinesia (LID) In Parkinsons Disease
2. Vanda Presents Data From Phase III Studies that Demonstrate Tasimelteon Restores Daily Cortisol Rhythm In Blind Patients With Non-24-Hour Disorder
3. AbbVie Presents Preliminary Results from Phase I Study of Investigational Oncology Compound ABT-199/GDC-0199 in Patients with High-Risk Chronic Lymphocytic Leukemia (CLL) at European Hematology Association Annual Meeting
4. Updated Results of Two Phase 2 Ibrutinib Studies in Patients with Mantle Cell Lymphoma or Diffuse Large B-cell Lymphoma
5. Ibrutinib Phase 2 Data: Analyses Show Efficacy with Ibrutinib Monotherapy in Patients with Relapsed or Refractory Mantle Cell or Diffuse Large B-cell Lymphoma
6. Lilly Voluntarily Terminates Phase II Study for LY2886721, a Beta Secretase Inhibitor, Being Investigated as a Treatment for Alzheimers Disease
7. NeuroDerm Announces Presentation of ND0612 Phase 1 and Phase 2 Results at the 2013 International Congress of Parkinsons Disease and Movement Disorders
8. Epizyme Enrolls First Patient in Phase 1/2 Clinical Trial of EPZ-6438, an Inhibitor of EZH2
9. Generex Announces Interview of MD Andersons Dr. Elizabeth Mittendorf, Principal Investigator on Companys AE37 Phase IIb Breast Cancer Efficacy Trial
10. Amgen Announces Top-Line Results Of Phase 3 Trebananib (AMG 386) TRINOVA-1 Trial In Recurrent Ovarian Cancer
11. SanBio Announces FDA Clearance for the Initiation of a Phase I/2a Clinical Trial Testing Their Cell Therapy Product, SB623, in Patients with Traumatic Brain Injury
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/14/2014)... 14, 2014 InformEx, North America,s ... chemistry, will hold the 30 th edition of its ... Convention Center from January 21-24. (Logo: http://photos.prnewswire.com/prnh/20131028/NY05330LOGO-a ... pharmaceutical, fine chemical and specialty chemical companies will take part ...
(Date:1/14/2014)... Va. , Jan. 14, 2014 Animal Emergency Critical Care, ... Leesburg, Virginia is the first in ... oxygen chamber. Dr. Susan M. Barnes , ... Dr. Barnes and husband, Dr. Cole Taylor , are avid ...
(Date:1/14/2014)... PORT WASHINGTON, New York , January 14, ... the leading provider of Closed System Transfer Devices (CSTD) for hazardous drugs, ... sales growth for the fourth straight year.   ... of exposure for pharmacy technicians, pharmacists, nurses and ...
Breaking Medicine Technology:Media Advisory: InformEx 2014 Events & Speaker Lineup for 30th Edition Conference in Miami Beach 2Hyperbaric Veterinary Medicine (hvm) Announces Animal Emergency Critical Care Installs A Small Animal Hyperbaric Chamber 2Equashield's Sales Grow by 60% in 2013 2
(Date:4/23/2014)... Ill. - In a country as wealthy as the United ... 12 seniors do not have access to adequate food due ... food insecure. , Recent research at the University of ... Survey (NHANES) revealed that the seniors who are dealing with ... , "In 2011, 8.35 percent of Americans over age 60 ...
(Date:4/23/2014)... Parents and physicians concerned about an increase in adolescents, ... breathe a sigh of relief. According to a new ... worth of data from states with and without medical ... increased use among adolescents. The study is published online ... Adolescent Health . , "Any time a state ...
(Date:4/23/2014)... Ritalin, may prevent the depletion of self-control, according to ... of the Association for Psychological Science. , Self-control can ... to focus attention on a boring textbook are hard ... for this difficulty: Exerting self-control for a long period ... on subsequent tasks. , "It is as if self-control ...
(Date:4/22/2014)... is a popular high school sport in the United ... study by researchers in the Center for Injury Research ... to compare and describe the occurrence and distribution patterns ... high school athletic training setting among adolescents and teens. ... of Athletic Training , examined data relating to adolescents ...
(Date:4/22/2014)... last few decades researchers have characterized a set of ... behavior in all types of species, from flies to ... but researchers surmise there are more. A team from ... Pennsylvania wondered if big-data approaches could find them. ... John Hogenesch, PhD, professor of Pharmacology and first author ...
Breaking Medicine News(10 mins):Health News:More Americans in their golden years are going hungry 2Health News:RI Hospital physician: Legalizing medical marijuana doesn't increase use among adolescents 2Health News:ADHD drug may help preserve our self-control resources 2Health News:New study finds 2.5 million basketball injuries to high school athletes in 6 seasons 2Health News:New study finds 2.5 million basketball injuries to high school athletes in 6 seasons 3Health News:Bioinformatics profiling identifies a new mammalian clock gene 2
... , , , ... ), a medical device company that develops, manufactures and markets innovative proprietary ... fiscal quarter ended June 30, 2009. , , "Our ... the fiscal year of growing U.S. Macroplastique sales and accumulating the clinical ...
... 3 Cephalon, Inc. (Nasdaq: CEPH ) today ... published data from a pivotal phase 3 study demonstrating that ... to chlorambucil in patients with chronic lymphocytic leukemia (CLL). ... 2008 U.S. Food and Drug Administration (FDA) approval of TREANDA ...
... TV raises risk more than other low-level activities, such as ... -- Young children who spend too much time in front ... at increased risk for high blood pressure, a new study ... sedentary behavior and blood pressure in 111 boys and girls, ...
... , , , ... supports those in transition from group coverage to individual coverage , ... Blue Cross and Blue Shield Association (BCBSA) today announced the launch ... a wide range of healthcare options to find coverage that best fits ...
... , , MANHATTAN, Kan., Aug. 3 ... a K-State researcher are making headway in the effort to control ... is a Regents Distinguished Professor at K-State,s College of Veterinary Medicine ... K-State and with outside collaborators is revealing the characteristics of the ...
... ST. LOUIS, Aug. 3 , , ... recently completed its yearly survey of in-house physician recruiters on the ... that the physician shortage, coupled with the aging population, has taken ... openings. Survey results were compiled between May 1 and May ...
Cached Medicine News:Health News:Uroplasty Reports First Fiscal Quarter Results 2Health News:Uroplasty Reports First Fiscal Quarter Results 3Health News:Uroplasty Reports First Fiscal Quarter Results 4Health News:Uroplasty Reports First Fiscal Quarter Results 5Health News:Uroplasty Reports First Fiscal Quarter Results 6Health News:Uroplasty Reports First Fiscal Quarter Results 7Health News:Uroplasty Reports First Fiscal Quarter Results 8Health News:Uroplasty Reports First Fiscal Quarter Results 9Health News:Uroplasty Reports First Fiscal Quarter Results 10Health News:Uroplasty Reports First Fiscal Quarter Results 11Health News:Uroplasty Reports First Fiscal Quarter Results 12Health News:Uroplasty Reports First Fiscal Quarter Results 13Health News:Journal of Clinical Oncology Publishes TREANDA Study Demonstrating Significant Improvement in Overall Response and Progression-Free Survival in Chronic Lymphocytic Leukemia 2Health News:Journal of Clinical Oncology Publishes TREANDA Study Demonstrating Significant Improvement in Overall Response and Progression-Free Survival in Chronic Lymphocytic Leukemia 3Health News:Journal of Clinical Oncology Publishes TREANDA Study Demonstrating Significant Improvement in Overall Response and Progression-Free Survival in Chronic Lymphocytic Leukemia 4Health News:Journal of Clinical Oncology Publishes TREANDA Study Demonstrating Significant Improvement in Overall Response and Progression-Free Survival in Chronic Lymphocytic Leukemia 5Health News:Young Kids' Screen Time May Raise Blood Pressure 2Health News:Blue Cross and Blue Shield Association Introduces Interactive Navigation Solution That Helps Individuals and Families Find Healthcare Coverage Options 2Health News:K-State Researcher, Collaborators Study Virulence of Pandemic H1N1 Virus; Work at K-State Would Protect Pig Industry If the Virus Jumps to Swine Populations 2Health News:PracticeMatch Releases Results of Recent 'State of the Industry' Survey of Physician Recruiters 2
... iFacts™ is the handheld ... Facts, a drug interaction ... brand and generic drugs. ... to refer to accurate ...
... Completely revised and updated for ... up-to-date guide to all aspects of ... comprehensive, easy to use catalog of ... off label commonly used in cancer ...
Nursing2006 Drug Handbook Entries include Alerts, dosage adjustments for specific populations, I.V. administration, off-label indications, adverse reactions, and more....
... A to Z Drug Facts produced ... information on thousands of medications. It ... side effect, drug interactions, patient information ... drug reference for physicians, students, residents, ...
Medicine Products: