Navigation Links
Safinamide Phase III Study Results Presented at 2013 MDS Meeting
Date:6/18/2013

ence of treatment emergent abnormalities in laboratory results, ophthalmological examinations, vital signs and ECG was similar in all groups.

Analyses (On treatment, ANCOVA-LOCF) performed in the ITT population showed treatment with safinamide 50-100 mg/day significantly improved ON-Time without troublesome dyskinesia compared to placebo by 0.96 ± 0.21 hours (p<0.01) in the ITT. Significant benefits of safinamide 50-100 mg/day were also reported in OFF-time, Motor symptoms (UPDRS III), PDQ39, EQ-5D, clinical global impression of change and severity, and OFF-time post morning dose of levodopa.

The abstract presented at the MDS is available for download at: http://www.newron.com/ENG/Default.aspx?SEZ=5&PAG=122 and

http://http://www.zambonpharma.com

About safinamide

Safinamide, an alpha-aminoamide, is currently being developed by Newron as an add-on therapy to dopamine agonists or to levodopa in patients with early or mid- to late-stage Parkinson's disease (PD). It is believed to have both dopaminergic and non dopaminergic activities, including selective and reversible inhibition of monoamine oxidase B (MAO-B), activity-dependent sodium channel antagonism and inhibition of glutamate release in vitro.

About Newron Pharmaceuticals

Newron (SIX: NWRN) is a biopharmaceutical company focused on novel therapies for diseases of the Central Nervous System (CNS) and pain. The Company is headquartered in Bresso near Milan, Italy. Based on the phase III results of safinamide for treatment of Parkinson's disease, Newron is working to expedite the global filing of the compound, together with its partners. Zambon Group has the rights to commercialise safinamide globally, excluding Japan and other key Asian territories, and Meiji Seika'/>"/>

SOURCE Newron Pharmaceuticals
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Adamas Pharmaceuticals Presents Positive Phase 2/3 Results For ADS-5102 For The Treatment Of Levodopa-Induced Dyskinesia (LID) In Parkinsons Disease
2. Vanda Presents Data From Phase III Studies that Demonstrate Tasimelteon Restores Daily Cortisol Rhythm In Blind Patients With Non-24-Hour Disorder
3. AbbVie Presents Preliminary Results from Phase I Study of Investigational Oncology Compound ABT-199/GDC-0199 in Patients with High-Risk Chronic Lymphocytic Leukemia (CLL) at European Hematology Association Annual Meeting
4. Updated Results of Two Phase 2 Ibrutinib Studies in Patients with Mantle Cell Lymphoma or Diffuse Large B-cell Lymphoma
5. Ibrutinib Phase 2 Data: Analyses Show Efficacy with Ibrutinib Monotherapy in Patients with Relapsed or Refractory Mantle Cell or Diffuse Large B-cell Lymphoma
6. Lilly Voluntarily Terminates Phase II Study for LY2886721, a Beta Secretase Inhibitor, Being Investigated as a Treatment for Alzheimers Disease
7. NeuroDerm Announces Presentation of ND0612 Phase 1 and Phase 2 Results at the 2013 International Congress of Parkinsons Disease and Movement Disorders
8. Epizyme Enrolls First Patient in Phase 1/2 Clinical Trial of EPZ-6438, an Inhibitor of EZH2
9. Generex Announces Interview of MD Andersons Dr. Elizabeth Mittendorf, Principal Investigator on Companys AE37 Phase IIb Breast Cancer Efficacy Trial
10. Amgen Announces Top-Line Results Of Phase 3 Trebananib (AMG 386) TRINOVA-1 Trial In Recurrent Ovarian Cancer
11. SanBio Announces FDA Clearance for the Initiation of a Phase I/2a Clinical Trial Testing Their Cell Therapy Product, SB623, in Patients with Traumatic Brain Injury
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)... May 28, 2015   Mast Therapeutics, Inc. ... leveraging its molecular adhesion and sealant technology (MAST) ... disease, heart failure, and arterial disease, today announced ... Company,s Board of Directors. Mr. Lief made this ... given his role as President and Chief Executive ...
(Date:5/28/2015)... May 28, 2015  Shareholder rights law firm ... certain officers and directors of Eleven Biotherapeutics, Inc. (NASDAQGM: ... Biotherapeutics is a clinical-stage biopharmaceutical company that engages ... to treat eye diseases, primarily in ... View this press release on the law firm,s ...
(Date:5/28/2015)... 2015 The amount Americans spend on healthcare ... with growth of 8% will reach $608 billion by ... directly on expenditures, co-pays as part of office visits ... The publisher made its finding in its most recent ... United States . Information on ...
Breaking Medicine Technology:Mast Therapeutics Announces Change In Board Of Directors 2Mast Therapeutics Announces Change In Board Of Directors 3Mast Therapeutics Announces Change In Board Of Directors 4Robbins Arroyo LLP Is Investigating the Officers and Directors of Eleven Biotherapeutics, Inc. (EBIO) on Behalf of Shareholders 2Report: U.S. Out-of-Pocket Healthcare Spending Reaches $416 Billion 2Report: U.S. Out-of-Pocket Healthcare Spending Reaches $416 Billion 3
... 4 Thoratec Corporation (Nasdaq: THOR ), a world ... and restore failing hearts, said today that revenues for the ... of nine percent over revenues of $80.8 million in the ... reflect a 14 percent increase in revenues from the company,s ...
... YORK, Nov. 4 NeoStem, Inc. (NYSE Amex: ... has been named to the Company,s Board of Directors. ... operating global biotechnology businesses. , Serving as Executive Vice ... global commercial operations of Abraxis Bioscience, a global biotechnology ...
Cached Medicine Technology:Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 2Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 3Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 4Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 5Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 6Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 7Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 8Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 9Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 10Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 11Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 12Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 13Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 14Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 15Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 16Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 17Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 18Thoratec Reports 14 Percent Growth in Cardiovascular Division Sales as Third Quarter Revenues Increase Nine Percent 19NeoStem, Inc. Names Edward Geehr, M.D. to Board of Directors; Biotechnology Executive Brings Scientific and Business Experience in Global Operations 2NeoStem, Inc. Names Edward Geehr, M.D. to Board of Directors; Biotechnology Executive Brings Scientific and Business Experience in Global Operations 3
(Date:5/28/2015)... Texas (PRWEB) May 28, 2015 Park Cities ... Group Dog Training class starting Saturday, June 6th ... the courtyard of 5831 McCommas Blvd in Dallas, with a ... classes will run for five weeks, with no class being ... the class is $135. , In this Intermediate-to-Advanced level class, ...
(Date:5/28/2015)... Three years ago, Dr. Jeffrey Gosin announced ... Vascular & Vein Center! Dr. Gosin’s center is ... is his mission to provide the highest quality care in ... Dr. Jeffrey Gosin is Board Certified in Surgery and Vascular ... and Jefferson Medical College. He completed a General Surgery residency ...
(Date:5/28/2015)... May 28, 2015 AMVETS leaders this ... prize winner Robert Davis of Newark, Del. AMVETS National ... him on winning the $10,000 sweepstakes grand prize. , ... 100,000 entries from around the country for prizes ranging ... took place on May 21 at the AMVETS National ...
(Date:5/28/2015)... Medelis, Inc., a specialty oncology CRO , ... the role of president. , “ Bill Taaffe has ... said Larry Flanagan, Medelis’ CEO and co-founder. “He will be ... phase of growth.” , Taaffe joined ICON’s U.S. clinical ... to over 4,500 employees, achieving 12 consecutive years of growth ...
(Date:5/28/2015)... 28, 2015 ISMETT , a leading ... boosted the Sicilian economy by €132.5 million in expenditure in ... of more than €73 million by retaining patients who otherwise ... a new study by the Battelle Memorial Institute. At the ... training and advanced health care management that is transforming Sicily ...
Breaking Medicine News(10 mins):Health News:Dallas-based Park Cities Pet Sitter to Offer “Training and Enrichment 2” Group Dog Training Class Beginning Saturday, June 6th, 2015. 2Health News:Dallas-based Park Cities Pet Sitter to Offer “Training and Enrichment 2” Group Dog Training Class Beginning Saturday, June 6th, 2015. 3Health News:Dr. Jeffrey Gosin is Celebrating Three Years at his Somers Point Location! 2Health News:Dr. Jeffrey Gosin is Celebrating Three Years at his Somers Point Location! 3Health News:AMVETS Announces Summer Sweepstakes Winners 2Health News:Bill Taaffe, Former President and CEO of ICON Clinical Research-US, Joins Medelis, a Specialty Oncology CRO, in the Role of President 2Health News:UPMC-Managed Transplant Hospital Drives Major Economic Benefits for Sicily, Study Finds 2Health News:UPMC-Managed Transplant Hospital Drives Major Economic Benefits for Sicily, Study Finds 3
... Holohan HealthDay Reporter , WEDNESDAY, Jan. 5 (HealthDay ... of chickenpox-related hospitalizations in the United States for the first ... And a second study has found that the ... Centers for Disease Control and Prevention in 2006, may offer ...
... doses of the varicella, or chickenpox, vaccine provide excellent protection ... severe disease. To be published in the February 1 issue ... support the two-dose vaccine regimen recommended in the United States ... study online.) The Centers for Disease Control and Prevention ...
... HealthDay Reporter , TUESDAY, Jan. 4 (HealthDay News) -- Up ... an increase that translates into many fewer injuries and deaths ... the first state law requiring seat belts was passed in ... But now, according to the U.S. Centers for Disease Control ...
... HealthDay Reporter , TUESDAY, Jan. 4 (HealthDay News) -- ... of the drug Avastin to treat breast cancer, a new ... odds of congestive heart failure in these patients. The ... Clinical Oncology , included almost 4,000 patients and found a ...
... DURHAM, N.C. A tiny light source and sensors at ... way to identify pre-cancerous cells in the lining of the ... successfully tested on patients during a clinical trial at the ... the promise of being a less invasive method for testing ...
... there is often concern about possible effects on the ... birth defects (thalidomide being a notorious example), and others ... about most drugs, level of risk. Researchers in the ... preclinical model for predicting a drug,s teratogenicity (tendency to ...
Cached Medicine News:Health News:Chickenpox Vaccine Cuts Hospitalization Rates: Study 2Health News:Chickenpox Vaccine Cuts Hospitalization Rates: Study 3Health News:Chickenpox Vaccine Cuts Hospitalization Rates: Study 4Health News:Study confirms 2 vaccine doses protect children from chickenpox 2Health News:Six Out of 7 Drivers Use Seat Belts: CDC 2Health News:Six Out of 7 Drivers Use Seat Belts: CDC 3Health News:More Evidence Links Avastin to Heart Failure in Breast Cancer Patients 2Health News:More Evidence Links Avastin to Heart Failure in Breast Cancer Patients 3Health News:Detecting esophageal cancer with light 2Health News:Model predicts a drug's likelihood of causing birth defects 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: