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STELARA(TM) Shows Greater Efficacy Than Etanercept for Treatment of Moderate to Severe Plaque Psoriasis: Phase 3 Comparator Study Published in The New England Journal of Medicine
Date:1/14/2010

>weight loss
  • warm, red, or painful skin or sores on your body
  • diarrhea or stomach pain
  • burning when you urinate or urinate more often than normal
  • feel very tired
  • are being treated for an infection
  • get a lot of infections or have infections that keep coming back
  • have TB, or have been in close contact with someone who has TB

  • After starting STELARA, call your doctor right away if you have any symptoms of an infection (see above).

    STELARA™ can make you more likely to get infections or make an infection that you have worse. People who have a genetic problem where the body does not make any of the proteins interleukin 12 (IL-12) and interleukin 23 (IL-23) are at a higher risk for certain serious infections that can spread throughout the body and cause death. It is not known if people who take STELARA™ will get any of these infections because of the effects of STELARA™ on these proteins.

    Cancer

    STELARA™ may decrease the activity of your immune system and increase your risk for certain types of cancer.  Tell your doctor if you have ever had any type of cancer.

    Reversible posterior leukoencephalopathy syndrome (RPLS)

    RPLS is a rare condition that affects the brain and can cause death. The cause of RPLS is not known. If RPLS is found early and treated, most people recover. Tell your doctor right away if you have any new or worsening medical problems including: headache, seizures, confusion and vision problems.

    Before receiving STELARA, tell your doctor if you:

    • have any of the conditions or symptoms listed above for serious infections, cancer, or RPLS
    • have recently received or are scheduled to receive an immunization (vaccine). People who take STELARA™
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    SOURCE Centocor Ortho Biotech Inc.
    Copyright©2010 PR Newswire.
    All rights reserved

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