Navigation Links
SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
Date:6/26/2009

ter treatment, including patients who tested negative for latent tuberculosis infections.

The use of TNF blocking agents including SIMPONI has been associated with reactivation of hepatitis B virus in patients who are chronic carriers of the virus. Some of these cases have been fatal. Chronic carriers of hepatitis B should be appropriately evaluated and monitored prior to the initiation of, during treatment with, and for several months following discontinuation of SIMPONI. In patients who develop HBV reactivation, SIMPONI should be discontinued.

Lymphomas have been observed in patients treated with TNF blocking agents, including SIMPONI. The incidence of non-lymphoma malignancies was similar to controls, and lymphoma is seen more often than in the general population. The potential role of TNF-blocking therapy in the development of malignancies is not known. Based on an exploratory clinical trial in patients with COPD, caution should be exercised when using any TNF-blocking therapy in COPD patients, as well as in patients with an increased risk for malignancy due to heavy smoking.

Worsening congestive heart failure (CHF) and increased mortality due to CHF have been reported with another TNF blocker. SIMPONI has not been studied in patients with CHF. SIMPONI should be used with caution in patients with mild heart failure and must be discontinued if new or worsening symptoms of heart failure appear.

TNF-blocking agents, including SIMPONI, have been associated in rare cases with new onset or exacerbation of demyelinating disorders, including multiple sclerosis. The benefits and risks of anti-TNF treatment should be carefully considered before initiation of SIMPONI therapy in patients with pre-existing or recent onset of demyelinating disorders.

There is limited safety experience of SIMPONI treatment in patients who have undergone surgical procedures, including arthroplasty.
'/>"/>

SOURCE Schering-Plough Corporation; Centocor Ortho Biotech Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine technology :

1. New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients
2. Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis
3. Transave Receives $2.2 Million Cystic Fibrosis Foundation Award for Development of ARIKACE(TM)
4. Cepheid Receives Grant to Develop Ten-Color Real-Time PCR Detection Technology for Use in the GeneXpert(R) System
5. DOR BioPharma Receives EMEA Agreement on the Design of its Confirmatory Phase 3 Clinical Trial of orBec(R) in GI GVHD
6. Malaria Vaccine Developer, Sanaria Inc., Receives 2009 Vaccine Industry Excellence Award for Best Early-Stage Vaccine Biotech
7. NeurogesX Receives FDA Orphan Drug Designation for Qutenza(TM) for Treatment of Postherpetic Neuralgia
8. AMT Receives EMEA Orphan Drug Designation for Acute Intermittent Porphyria
9. Terumo Heart, Inc. Reaches Clinical Milestone as the 100th Patient Worldwide Receives the DuraHeart(TM) Left Ventricular Assist System
10. Agennix Receives Fast Track Designation From FDA for Talactoferrin in Combination With Sunitinib for Renal Cell Carcinoma
11. Pelleve Receives FDA Clearance for the Treatment of Mild to Moderate Facial Wrinkles
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/1/2015)... Calif. , May 1, 2015  Legendary actor ... Inc. in a new PBAFacts campaign designed to educate ... to learn more about Pseudobulbar Affect (PBA) and to ... idea that an actor has the ability to cry ... the lack of control experienced by people living with ...
(Date:5/1/2015)... PORTLAND, Ore. , May 1, 2015 ... medical risk assessment company that develops, manufactures and markets ... evaluating chronic diseases, today reported financial results for the ... "In the first quarter of 2015, Semler reported continued ... sequential quarter over quarter revenue growth of 14%," said ...
(Date:5/1/2015)... -- Cambrex Corporation (NYSE: CBM ) reports results for ... Highlights , Sales increased 18% compared to the ... impact, driven by Innovator products and Controlled Substances. , ... first quarter of 2014. , GAAP Diluted EPS from ... last year and Adjusted Diluted EPS was $0.29 compared to ...
Breaking Medicine Technology:Danny Glover Joins PBA Facts Campaign, to Educate and Build Awareness of Pseudobulbar Affect (PBA), a Little Known but Widespread Neurologic Condition 2Danny Glover Joins PBA Facts Campaign, to Educate and Build Awareness of Pseudobulbar Affect (PBA), a Little Known but Widespread Neurologic Condition 3Semler Reports First Quarter 2015 Financial Results 2Semler Reports First Quarter 2015 Financial Results 3Semler Reports First Quarter 2015 Financial Results 4Semler Reports First Quarter 2015 Financial Results 5Cambrex Reports First Quarter 2015 Financial Results 2Cambrex Reports First Quarter 2015 Financial Results 3Cambrex Reports First Quarter 2015 Financial Results 4Cambrex Reports First Quarter 2015 Financial Results 5Cambrex Reports First Quarter 2015 Financial Results 6Cambrex Reports First Quarter 2015 Financial Results 7Cambrex Reports First Quarter 2015 Financial Results 8Cambrex Reports First Quarter 2015 Financial Results 9Cambrex Reports First Quarter 2015 Financial Results 10Cambrex Reports First Quarter 2015 Financial Results 11
(Date:5/3/2015)... 03, 2015 HealthPostures, a pioneering ... announces its appearance at the , May 5 - ... HealthPostures will exhibit at the conference include its bestselling ... stand solutions is the 6100 TaskMate Executive. Features of ... an adjustable keyboard tray, extended platform work surface and ...
(Date:5/2/2015)... 2015 Vancouver fencing company, QS Fencing, has ... advice to prospective clients related to their questions on railings ... railings around their decks and patios. While that seems like ... up once the person rolls up their sleeve to start ... railing in finding a gate that matches it. , Instead ...
(Date:5/2/2015)... May 02, 2015 It’s a pattern ... natural disaster strikes anywhere on this planet, cyber scammers ... sympathy and compassion for their own personal gain. ... Emergency Readiness Team) issued an alert titled “Nepal ... email scams citing the earthquake in Nepal. The scam ...
(Date:5/2/2015)... East Liverpool, Ohio (PRWEB) May 02, 2015 ... of East Liverpool City Hospital (ELCH) gathered to celebrate ... direction of River Valley Health Partners (RVHP), had zero ... and zero urinary catheter associated infections. ELCH was also ... , The management team at ELCH credited the ...
(Date:5/2/2015)... OR (PRWEB) May 02, 2015 ZoomCare, ... it has submitted plans to offer its new healthcare ... Exchange. The ZOOM+ Personal Health Insurance System is the ... up to enhance human performance. ZOOM+ Personal Health Insurance ... healthcare delivery system that are subject to review and ...
Breaking Medicine News(10 mins):Health News:HealthPostures to Appear at the Minnesota Safety and Health Conference 2Health News:HealthPostures to Appear at the Minnesota Safety and Health Conference 3Health News:Professional Staff at QS Fencing Company Now Provides Advice on Railings and Gates 2Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 2Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 3Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 4Health News:East Liverpool City Hospital Celebrates Patient Care Improvements 2Health News:ZoomCare Applies to be on Oregon Exchange 2
... to be presented today at the Society for Maternal-Fetal Medicine,s ... researchers will present findings that show that many women are ... their routine third trimester screening and a rapid test performed ... a leading cause of neonatal infection. GBS is a bacterium ...
... and older, includes nearly 3.8 million divorced men and ... end-of-life issues can be particularly difficult for singles without ... University of Missouri provides insight into the experiences of ... assistance with daily tasks and management of health needs. ...
... -- More than one-quarter of women with apparent early-stage ... check for cancer spread, which nearly doubles these patients, ... at the University of California Davis Cancer Center and ... registry data of 721 presumed early-stage ovarian cancer patients ...
... HealthDay Reporter , THURSDAY, Feb. 10 (HealthDay News) -- In ... researchers found that taking folate during pregnancy didn,t appear ... data do not support a protective effect of folate on ... have an adverse effect on pregnancy either," said study author ...
... Bayston in the School of Clinical Sciences, PhD student and ... professional training fellowship of almost 160,000 from Arthritis Research UK ... with broken bones. Pins used to mend broken ... cent of patients being treated in this way develop infections, ...
... than two thousand physicians, some of the top ... medicine, especially high risk pregnancies, gathered today for ... four days of intensive research presentations. Presentations ... (SMFM) annual meeting, The Pregnancy Meeting , represent ...
Cached Medicine News:Health News:Third trimester group B streptococcus test doesn't accurately predict presence during labor 2Health News:Study examines phenomenon of women caring for ex-husbands 2Health News:Folate May Not Protect Against Premature Birth 2Health News:Folate May Not Protect Against Premature Birth 3Health News:Anti-bacterial collar to help mend broken bones 2Health News:SMFM highlights significance of spina bifida research findings 2
Desmarres Retractor Size 4...
Desmarrres Lid Retractor, round serrated handle, polished finish, overall length 130 mm....
Size 4 - 2.25 mm...
Highly versatile, efficient, compact and accurate digital readout display....
Medicine Products: