Navigation Links
SGX Initiates Phase I Trials for SGX523
Date:1/16/2008

than 200 protein kinases and has demonstrated both potent in vitro blockage of the activity of this cancer target and in vivo activity against various types of human cancer cells that depend on cMET for their uncontrolled growth and proliferation. The cMET receptor tyrosine kinase has been implicated in a wide range of cancers, including both solid and blood tumors. cMET has been extensively studied in the laboratory environment and, to a lesser extent, in the clinic, with increasing data suggesting that uncontrolled stimulation of cMET plays a key role in a variety of effects associated with cancer, including cellular growth, increased cell movement and invasion, and an increased ability of cancer cells to metastasize. Other observations have implicated cMET in increased angiogenesis. cMET activation has been observed in a wide range of other cancer types including breast, colon, prostate, pancreatic and gastric cancers.

About SGX Pharmaceuticals

SGX Pharmaceuticals is a biotechnology company focused on the discovery, development and commercialization of innovative cancer therapeutics. The SGX oncology pipeline includes drug candidates from its FAST(TM) drug discovery platform, such as next generation BCR-ABL inhibitors being developed by SGX and in partnership with Novartis and cMET tyrosine kinase inhibitors, including SGX523, and JAK2 inhibitors. More information on the pipeline and drug discovery platform can be found at http://www.sgxpharma.com and in the Company's various filings with the Securities and Exchange Commission.

Forward Looking Statements

Statements in this press release that are not strictly historical in nature are forward-looking statements. These statements include, but are not limited to, the potential of SGX523 as a treatment for certain cancers, the potential outcome of Phase I clinical studies of SGX523, the role of cMET in cancer, statements regarding bringin
'/>"/>

SOURCE SGX Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Kosan Initiates Phase 2 Trial of Alvespimycin, Second-Generation Hsp90 Inhibitor, in HER2-Positive Metastatic Breast Cancer
2. Arena Pharmaceuticals Announces Positive Phase 1a Clinical Trial Results of APD791 for the Treatment of Arterial Thrombosis and Initiates Phase 1b Clinical Trial
3. Corthera Initiates Phase II Clinical Trial of Relaxin in Acute Heart Failure
4. Trius Initiates U.S. Phase I Trial for its Oxazolidinone Antibacterial Drug, TR-701
5. Sangart, Inc. Initiates Dosing in Phase II Study of Hemospan(R) in Chronic Critical Limb Ischemia
6. Exelixis Initiates Phase 1/2 Trial of XL184 in Patients With Non-Small Cell Lung Cancer
7. NicOx Announces Pfizer Initiates Phase 2 Clinical Development for PF-03187207 in Japan
8. Intra-Cellular Therapies Initiates Phase 2 Clinical Trial for Sleep Maintenance Insomnia
9. Alseres Pharmaceuticals Initiates the ALTROPANE(R) POET-2 Phase III Clinical Trial Program
10. Chimerix Initiates a Multi-dose Clinical Trial of the Companys Lead Compound, CMX001, for the Treatment for Smallpox Infection
11. Glenmark Initiates Phase 2 Trial for Crofelemer for Acute Infectious Diarrhea
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... , July 25, 2014  Corporate libraries are ... understanding new advancements in technology and how to cope ... libraries in the pharmaceutical and medical device industries are ... the information and services they provide. ... LLC there are many forces of change that leading ...
(Date:7/25/2014)... 25, 2014  Smile Train and its technology partner ... Virtual Surgery Simulator among leading global health innovations in ... in Washington, D.C. at The ... "Smile Train is honored to be represented ... of innovators in health and medicine that TEDMED unites ...
(Date:7/25/2014)... LAS VEGAS , July 25, 2014 GrowBLOX ... of a binding Memorandum of Understanding ("MOU") with LaurelCo, LLC, ... to pursue the acquisition of both cultivation and dispensary medical ... . Pursuant to the MOU, GBLX will acquire a 20% ... use our proprietary GrowBLOX TM growing chambers, as well ...
Breaking Medicine Technology:Forces of Change Reshaping Corporate Libraries & Information Services 2Smile Train and BioDigital Selected to Showcase Virtual Surgery Simulator in The Hive at TEDMED 2014 2Smile Train and BioDigital Selected to Showcase Virtual Surgery Simulator in The Hive at TEDMED 2014 3GrowBLOX Sciences, Inc. Partners with LaurelCo, LLC to Obtain Licenses to Cultivate and Dispense Medical Marijuana in Illinois 2GrowBLOX Sciences, Inc. Partners with LaurelCo, LLC to Obtain Licenses to Cultivate and Dispense Medical Marijuana in Illinois 3
(Date:7/27/2014)... New York, NY (PRWEB) July 27, 2014 ... and Tea Production industry has fared well, thanks ... tea and coffee blends. According to the Coffee Association ... data available), Canadians consume 2.7 cups of coffee per ... shed light on the health benefits of drinking tea ...
(Date:7/27/2014)... (PRWEB) July 27, 2014 The European ... market in Europe with analysis and forecast of revenue. ... grow from around $509.4 million in 2013 to $657.1 ... 2013 to 2018. , Browse through the TOC of ... idea of the in-depth analysis provided. It also provides ...
(Date:7/27/2014)... 2014 As Tylenol lawsuits ... move forward in federal court, Bernstein Liebhard LLP ... of the benefits purportedly associated with acetaminophen, the ... which appears in the The Lancet, looked at ... whom were given either acetaminophen or a placebo ...
(Date:7/27/2014)... Ticket Down is a reputable source ... in Miami, FL at the Sun Life Stadium on August ... underway. In the opening game, Olympiacos from Superleague Greece defeated ... an early lead in their group. Six other teams will ... including Manchester City, Manchester United, AS Roma, Liverpool FC, Inter ...
(Date:7/27/2014)... WA (PRWEB) July 27, 2014 Individuals that ... injury would greatly benefit from the newly released ebook ... claims. , Designed to help those struggling through the ... type of accident, the ebook guide attempts to help individuals ... full health with the help of their doctors and an ...
Breaking Medicine News(10 mins):Health News:Coffee and Tea Production in Canada Industry Market Research Report Now Available from IBISWorld 2Health News:Coffee and Tea Production in Canada Industry Market Research Report Now Available from IBISWorld 3Health News:Europe Agricultural Adjuvants Market is Expected to Reach $657.1 million in 2018 - New Report by MicroMarket Monitor 2Health News:Europe Agricultural Adjuvants Market is Expected to Reach $657.1 million in 2018 - New Report by MicroMarket Monitor 3Health News:Europe Agricultural Adjuvants Market is Expected to Reach $657.1 million in 2018 - New Report by MicroMarket Monitor 4Health News:Europe Agricultural Adjuvants Market is Expected to Reach $657.1 million in 2018 - New Report by MicroMarket Monitor 5Health News:As Tylenol Lawsuits Mount, Bernstein Liebhard LLP Notes Study Questioning Some Benefits Purportedly Associated with Acetaminophen 2Health News:As Tylenol Lawsuits Mount, Bernstein Liebhard LLP Notes Study Questioning Some Benefits Purportedly Associated with Acetaminophen 3Health News:As Tylenol Lawsuits Mount, Bernstein Liebhard LLP Notes Study Questioning Some Benefits Purportedly Associated with Acetaminophen 4Health News:Guinness International Champions Cup Finals Tickets: Ticket Down Slashes Ticket Prices for International Champions Cup Finals in Miami at Sun Life Stadium 2Health News:Guinness International Champions Cup Finals Tickets: Ticket Down Slashes Ticket Prices for International Champions Cup Finals in Miami at Sun Life Stadium 3Health News:Auto Accident Personal Injury Ebook Guide Released by The Jones Firm 2
... An Indian origin scientist at the Rensselaer Polytechnic ... build artificial muscles using carbon nanofibres .,Artificial muscles ... creating a smoother, more human-like motion than jerky ... could be used to power robots, prosthetic limbs ...
... Food Safety Authority (NZFSA) has issued a warning to the ... fear that it has additives not cleared for use in ... the safety of baby food in the country. ,The ... in the baby formula. ,Four Nutricia Karicare Gold Plus ...
... health institutions found to be violating various health laws . ... arrest and prosecute the operators of these institutions. ,In ... shops which constitute immeasurable health hazards to its innocent ... health facilities in different parts of the state. ...
... has been an alarming rise in the number of suicides ... way back in 1989 . Unfortunately, most such incidents have ... were 736 cases of attempted suicide from 2001 until May ... quite different. ,,The records of just one major hospital ...
... and final Harry Potter book has been leaked on the internet, ... of the pages, said to be from the US edition of ... to a number of websites, that have seen a deluge of ... ,If the leak is not a hoax, then the photographs reveal ...
... calculations are a knotty affair for most young adults in ... 14 of them cannot solve basic maths questions meant for ... survey was conducted to mark the release of the ITV ... , ,The brain gain software props up pre-school children to ...
Cached Medicine News:Health News:Additives in Baby Products Raise Fresh Concerns in New Zealand 2Health News:Nigerian Health Authority Crackdown On Sub-Standard Health Institutions 2Health News:Kashmir Battles Alarming Increase in Suicides 2Health News:Kashmir Battles Alarming Increase in Suicides 3
The CD Horizon Antares Spinal System represent a new addition to the CD Horizon Spinal System. It is based around a new, anatomically designed "pringle shaped" staple that allows for the placement of...
... Moss Miami is a universal hook, rod, and ... spinal procedures. The Moss Miami system utilizes a ... screws, and a dual closure mechanism. The load ... for proper tension band principle to be applied ...
BLF21A Alarm Model measures microcirculation in 1 cubic mm of tissue for real-time assessment of perfusion....
A portable, easy to use, dual-channel laser-Doppler tissue perfusion and temperature monitoring system, at a remarkably affordable price....
Medicine Products: