Navigation Links
SEQUEL Trial Results for Qnexa® Published in AJCN Show 10% Sustained Weight Loss Over 2 Years
Date:12/8/2011

MOUNTAIN VIEW, Calif., Dec. 8, 2011 /PRNewswire/ -- VIVUS, Inc. (NASDAQ: VVUS) today announced that results from the SEQUEL study were published in The American Journal of Clinical Nutrition, a peer-reviewed journal with broad, multidisciplinary readership. The SEQUEL study evaluated the long-term efficacy and safety of Qnexa in 676 overweight and obese subjects with cardiometabolic disease. In addition to 10% sustained weight loss, the study also found that significantly more placebo patients became diabetic over the two years as compared to patients treated with Qnexa. The data suggest that Qnexa, in conjunction with lifestyle modification, may provide a well-tolerated and effective option for the sustained treatment of obesity and the potential to prevent many in this population from progressing to type 2 diabetes.

"Recent data show that diabetes, like obesity, has become a rapidly growing epidemic, with nearly 1 in 10 adults potentially affected by the disease," said lead investigator W. Timothy Garvey M.D., director of the Nutrition Obesity Research Center, University of Alabama at Birmingham. "Results from the SEQUEL study underscore Qnexa's potential as a non-surgical option for sustained weight loss and improvements in comorbidities in overweight and obese patients."

Specific results as published in AJCN are as follows:

  • Patients treated with Qnexa had significant, sustained weight loss compared to those in the placebo group over two years. 
  • Average weight loss at week 108 was -9.3% and -10.5%, respectively, for the mid- and top-dose as compared to -1.8% for the placebo group (least-squares mean ITT-LOCF).
  • Qnexa patients had improved cardiovascular and metabolic risk factors and a decrease in the need for associated medications in comparison with the placebo group.
  • Placebo patients had a three times greater li
    '/>"/>

  • SOURCE VIVUS, Inc.
    Copyright©2010 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6

    Related medicine technology :

    1. Additional Analysis from Two-Year Sequel Study of QNEXA Featured at The 2011 Annual Scientific Meeting of The Obesity Society
    2. Data From QNEXA Sequel Study Featured at the 47th EASD Annual Meeting
    3. SequelMed EMR Version 8 Certified by Ohio Board of Pharmacy
    4. Sequel Systems, Inc. Meaningful Use EHR Receives ONC-ATCB 2011/2012 Certification
    5. Sequella and University of Maryland Restate Exclusive License for Jointly Owned Event Marker System Technology
    6. Sequella Receives American Recovery and Reinvestment Funding Through the NIH
    7. Sequella Lead Drug Compound SQ109 Selected for Phase 1B Clinical Trial Program
    8. Sequella Presents Data on Synergy Between Investigational New TB Drugs SQ109 and TMC207
    9. TIs new MSP430™ microcontrollers enable more performance and higher precision in home automation, industrial and portable medical applications
    10. GiiResearch.com: Computed Tomography (CT) Systems - Technological Advances and Positive Clinical Trial Evidences to Drive the Market
    11. GiiResearch.com: Insulin Pumps - Availability of Reimbursement and Favorable Clinical Trial Data to Drive Market Growth
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:7/28/2014)... Concord Medical Services Holdings Limited ("Concord Medical" or the ... hospital management solution provider and operator of the largest ... China , today announced that on July ... cash dividend of US$0.30 per ordinary share (or US$0.90 ... ordinary shares. The total expense for the special dividend ...
    (Date:7/28/2014)... CHAPEL HILL, N.C. , July 28, 2014 /PRNewswire/ ... results of a clinical trial demonstrating that CXL-1427, a ... was well tolerated in healthy volunteers. The company has ... failure in a Phase IIa clinical trial designed to ... as its dosing levels. The Phase I ...
    (Date:7/28/2014)... 2014  Isis Pharmaceuticals, Inc. (NASDAQ: ISIS ... Financial Results and Highlights Conference CallWhen:Monday, August 4 at ... How:Live on the Internet. Simply log onto our website ... the live event, a replay of the webcast will ... . ABOUT ISIS PHARMACEUTICALS, INC. Isis is ...
    Breaking Medicine Technology:Concord Medical Declares Special Dividend 2Cardioxyl Pharmaceuticals Successfully Completes First Clinical Trial For Heart Failure Drug CXL-1427 2Webcast Alert: Isis Pharmaceuticals' Second Quarter 2014 Financial Results Conference Call 2
    ... May 10, 2011 Cobalis Corp. (CLSC.PK) announced today ... PreHistin® Allergy Defense Formula , on major national cable ... commercials, featuring leading US allergist Dr. Paul H. Ratner, ... of allergies, giving seasonal and year-round sufferers the first ...
    ... is being released by SafeMinds ( www.SafeMinds.org ): ... publicly denied a vaccine-autism link, while at the same ... awarding damages for vaccine injury to children with brain ... verifiable government data, breaks ground in the controversial vaccine-autism ...
    Cached Medicine Technology:Cobalis Corp. Launches National Television Commercials for PreHistin® Allergy Defense Formula 2Cobalis Corp. Launches National Television Commercials for PreHistin® Allergy Defense Formula 383 Cases of Autism Associated with Childhood Vaccine Injury Compensated in Federal Vaccine Court 2
    (Date:7/28/2014)... “China Surgical Generators Market Outlook ... China Surgical Generators market. The report provides value, ... and average prices (in US dollars) within market ... and Argon Plasma Coagulation Generators. , The report ... for each of these market categories, and global ...
    (Date:7/28/2014)... 2014 Quincy Bioscience, makers of the ... to announce the release of the fourth edition of ... co-founder Mark Underwood. , The Brain Health Guide is ... techniques for readers to improve memory and promote optimal ... The Brain Health Guide provides ways to help minimize ...
    (Date:7/28/2014)... treat severe chronic migraine headaches led to significant symptom ... patients treated at Massachusetts General Hospital (MGH). Physicians ... report that more than half of 35 patients treated ... headaches associated with compression of craniofacial nerves reported ... paper has received advance online publication in the journal ...
    (Date:7/28/2014)... Massachusetts (PRWEB) July 28, 2014 ... Summit Provider Exchange technology solution in ... integration efforts and support collaboration with their New ... bed acute-care medical center located in New Jersey, ... seasonal visitors with a variety of inpatient and ...
    (Date:7/28/2014)... July 28, 2014 (HealthDay News) -- Endurance runners are ... an undetected heart condition, according to a new study. ... participating in events in warm climates are actually 10 ... stroke. Yet, the less common sudden death of a ... problems, such as an irregular heartbeat, often gets a ...
    Breaking Medicine News(10 mins):Health News:Key Market Data on China Surgical Generators Market to 2020 Report Available at MarketOptimizer.org 2Health News:Key Market Data on China Surgical Generators Market to 2020 Report Available at MarketOptimizer.org 3Health News:Key Market Data on China Surgical Generators Market to 2020 Report Available at MarketOptimizer.org 4Health News:Quincy Bioscience Launches the Fourth Edition of The Brain Health Guide 2Health News:Non-endoscopic migraine surgery provides significant symptom relief 2Health News:Cape Regional Medical Center Chooses Summit Provider Exchange to Connect With NJSHINE and Physician Offices 2Health News:Cape Regional Medical Center Chooses Summit Provider Exchange to Connect With NJSHINE and Physician Offices 3Health News:Heat Stroke a Greater Threat to Endurance Runners Than Heart Problems: Study 2
    ... lives can greatly affect his or her risk for asthma. ... neighborhood differences in rates of childhood asthma may be explained ... heating oil. Results appear online in the Journal of ... City, where the study was conducted, asthma among school-age children ...
    ... March 26, 2012, Cleveland, OH -- Overweight, diabetic ... or remission of their diabetes, according to new ... controlled trial, some weight loss surgery patients achieved ... diabetes medications. In others, the need for insulin ...
    ... Reporter , MONDAY, March 26 (HealthDay News) -- Most people who ... heart attack, but it can take hours or days to make ... special kind of CT scan given in the emergency room seems ... can be sent home safely sooner. "You can go to ...
    ... Lisa Esposito HealthDay Reporter , MONDAY, March ... Monday began its review of the constitutionality of the ... Care Act. And the justices gave every indication that ... from hearing the case. The Affordable Care Act ...
    ... RDMS, will be honored with the Distinguished Sonographer Award ... (AIUM) Annual Convention at the JW Marriott Desert Ridge ... 2012. The Distinguished Sonographer Award is a means of ... have significantly contributed to the growth and development of ...
    ... , MONDAY, March 26 (HealthDay News) -- Very few ... fertility while undergoing cancer treatment, a new study says. ... need more information about fertility preservation methods such as ... the University of California, San Francisco, and colleagues. ...
    Cached Medicine News:Health News:Air pollution from trucks and low-quality heating oil may explain childhood asthma hot spots 2Health News:Cleveland Clinic study shows bariatric surgery improves, reverses diabetes 2Health News:Cleveland Clinic study shows bariatric surgery improves, reverses diabetes 3Health News:CT Scans Can Spot Heart Trouble Fast 2Health News:CT Scans Can Spot Heart Trouble Fast 3Health News:Supreme Court Begins Review of Affordable Care Act 2Health News:Supreme Court Begins Review of Affordable Care Act 3Health News:Supreme Court Begins Review of Affordable Care Act 4Health News:Supreme Court Begins Review of Affordable Care Act 5Health News:Supreme Court Begins Review of Affordable Care Act 6Health News:Supreme Court Begins Review of Affordable Care Act 7Health News:Few Young Women With Cancer Take Steps to Preserve Fertility 2
    Get YAG laser performance from your diode laser. Our proprietary NA shift technology offers efficient coupling of low divergence fiber to high divergence lasers...
    One piece, 100% fused silica construction offers low scatter and high efficiency...
    ... Ultrafin™ Stirrup is the latest ... stirrup features a roomier boot ... up to an 800 pound ... to position heavy legs more ...
    The new series of Steris Power-lift Stirrups incorporate all of the proven clinical benefits of Allen-style booted stirrups: maximum safety for the patient, ease of setup for your staff, impressive v...
    Medicine Products: