Navigation Links
SCAI: CARDia Data Find Diabetic Patients With Complex Heart Disease Can Safely Choose PCI

At One Year, Angioplasty and Stenting Matches Bypass Surgery for Safety and

Effectiveness in Patients with Complex Medical Condition

WASHINGTON, Sept. 1 /PRNewswire/ -- Patients with both diabetes and advanced blockages in at least three heart vessels will find good news in new findings announced today from the CARDia trial, says The Society for Cardiovascular Angiography and Interventions (SCAI). The one-year findings of the new study indicate that these patients can safely choose to undergo angioplasty and stenting rather than open-heart surgery.

At the European Society of Cardiology Congress (Munich, Germany), investigators from the United Kingdom presented the results of CARDia (Coronary Artery Revascularization in Diabetes), a clinical trial comparing percutaneous coronary intervention (PCI) vs. open-heart surgery in patients typically considered to be poor candidates for angioplasty and stenting. Since the combination of diabetes and multi-vessel coronary artery disease has long been considered the domain of surgeons, their findings surprised some: The patients who underwent PCI rather that surgery did just as well as the surgery patients on the primary endpoint of death, heart attack, and stroke. In addition, the PCI patients experienced fewer strokes and less bleeding.

This finding differs from earlier trials comparing PCI and surgery in these patients, perhaps because drug-eluting stents have been added to the mix, suggest SCAI leaders. "The take-away message is that diabetic patients with complex coronary artery disease may now be able to choose angioplasty and stenting over bypass surgery," says Dr. Bonnie Weiner, SCAI Immediate Past President, Professor of Medicine, and Director of Interventional Cardiology Research at St. Vincent Hospital at Worcester Medical Center (Worcester, MA). "It's important to realize that this is one trial and the first-year findings, but it's a good sign for patients because it could ultimately broaden their options."

CARDia also examined whether, after undergoing PCI or surgery, patients required a repeat procedure. The difference in repeat revascularization between PCI and bypass surgery was very small but statistically significant, despite an unusually low rate for both groups (9.9% for PCI vs. 2.0% for bypass; p=0.001). Further, when the patients who received drug-eluting stents (rather than bare metal stents or the entire study population) were specifically analyzed, the difference in revascularization in the PCI group was even lower, and the difference in the rates of repeat revascularization was less important (7.3% for PCI vs. 2.0% for bypass; p=0.013). This represented about two-thirds of the study population and more closely reflects current practices.

"When you compare only the patients who had angioplasty with drug-eluting stents with the bypass surgery patients, you find very similar repeat revascularization rates," says Dr. Weiner. "We'll want to see if these findings continue as the follow-up proceeds since the surgery patients are less likely to have repeat revascularization procedures this early, but it's a very good sign for patients who are candidates for PCI and prefer it because it is less invasive and easier to recover from than surgery. In our view, this is very good news for patients because it gives them more options for their care."

About SCAI

Headquartered in Washington, D.C., The Society for Cardiovascular Angiography and Interventions is a 4,000-member professional organization representing invasive and interventional cardiologists in more than 60 countries. SCAI's mission is to promote excellence in invasive and interventional cardiovascular medicine through physician education and representation, and advancement of quality standards to enhance patient care. SCAI's annual meeting has become the leading venue for education, discussion, and debate about the latest developments in this dynamic medical specialty. SCAI's new patient and physician education program, Seconds Count, offers comprehensive information about cardiovascular disease. For more information about SCAI and Seconds Count, visit or

SOURCE Society for Cardiovascular Angiography and Interventions(SCAI)
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. FluoroPharma Announces Positive Phase I Safety Results for BFPET(TM), Myocardial Perfusion Imaging (MPI) Tracer for Positron Emission Tomography (PET)
2. Heart Patients More Likely to Adopt Healthy Habits in 3-Year Program Led by Cardiac Rehabilitation Experts, Mayo Clinic Research Shows
3. CPR Data Debriefing by Hospital Responders Improves CPR Performance and Increases Initial Survival Rate Following Cardiac Arrest
4. Daiichi Sankyo/Eli Lillys Effient and Astrazenecas Ticagrelor May Offer Advantages in the Treatment of Post-Myocardial Infarction
5. XIENCE(TM) V Drug Eluting Stent from Abbott Outperforms Market-Leading Stent in Reducing Major Adverse Cardiac Events at Two Years
6. Cardica Reports Positive Top-Line Results and Submits 510(k) for PAS-Port(R) Proximal Anastomosis System in Cardiac Bypass Surgery
7. Cardiac Safety Study of Stinger S-200 Published
8. Orqis(R) Medicals Cancion(R) System Significantly Increases Cardiac Performance
9. CV Therapeutics Anti-Ischemic Therapy Ranexa(R) Significantly Reduces Cardiac Chest Pain Symptoms and Recurrent Ischemia in MERLIN-TIMI 36 Patients With Angina
10. CorMatrix(R) Announces Intramyocardial Injection of Emulsified ECM Technology(TM) Demonstrates Enhanced Angiogenesis and Improved Cardiac Function in a Preclinical Model
11. Ranolazine Shortens QT Interval and Improves Cardiac Relaxation in Study of Patients With Genetic Sodium Channel Disorder
Post Your Comments:
(Date:11/30/2015)... VIEW, Calif. , Nov. 30, 2015 ... been the norm in U.S. medical imaging ... The increasingly popular accountable care payer-provider contracts ... models and, in their wake, alter provider-vendor ... quality-based payments will push forward new purchasing ...
(Date:11/30/2015)... and SAN DIEGO , ... Pharmaceuticals, Inc. (NASDAQ: ARNA ) today announced that ... for filing the New Drug Application (NDA) for an ... release formulation will offer patients a chronic weight management ... ® ) is currently approved as an adjunct to ...
(Date:11/30/2015)... and ST. LOUIS , Nov. 30, ... ESRX ) today announced an early renewal of ... began in 1999, will now extend through at least ... After evaluating pharmacy benefit manager capabilities during a ... Scripts continues to offer the best health plan integration ...
Breaking Medicine Technology:
(Date:11/30/2015)... ... 2015 , ... The recently published 32nd Annual Report of ... that in 2014, someone called a poison center about every 11 seconds. America’s ... human exposure cases. , The American Association of Poison Control Centers (AAPCC) maintains ...
(Date:11/30/2015)... ... November 30, 2015 , ... The Foundation for Breast ... and prevention—is joining forces with the award-winning creator and writer of Downton Abbey ... 7, 2015 at the Union League of Philadelphia. , The benefit, titled ...
(Date:11/30/2015)... , ... November 30, 2015 , ... ... magazine, quoted Michael Hansen, Ph.D., a senior scientist at Consumer Reports as supporting ... so for a child’s exposure limits. , The original Nov 2015 CR story ...
(Date:11/30/2015)... ... November 30, 2015 , ... An inventor from Charlottesville, Va., is concerned about ... baby had high blood pressure due to loud noises," she said, "so I decided ... noise pollution as well as radio waves and microwaves." , The baby BABY MUFF ...
(Date:11/30/2015)... CHICAGO (PRWEB) , ... November ... ... introduced two new additions to its industry-leading suite of automated breast density ... of North America (RSNA) meeting, November 29-December 4, 2015 (South Hall booth ...
Breaking Medicine News(10 mins):