Navigation Links
SARcode Bioscience Announces Acquisition by Shire US Holdings Inc.
Date:3/25/2013

track record of SARcode, we believe the near-term milestones are attainable, and would result in an excellent venture-level multiple for all investors," he added.   Institutional investors in SARcode Bioscience include Alta Partners, Clarus Venture Partners, Rho Ventures and Sofinnova Ventures.

The ongoing lifitegrast clinical development program includes two pivotal Phase 3 studies, called OPUS-1 and OPUS-2.  The 700-patient OPUS-2 study, which commenced earlier this year, will aim to build on the positive sign and symptom data resulting from OPUS-1. The results from these two studies, along with data from an ongoing year-long safety study called SONATA, will support a planned New Drug Application.

About Lifitegrast

Lifitegrast is an investigational novel small-molecule integrin antagonist that was "purpose-built" to meet several specifications that would make it an ideal dry eye therapy candidate.  It was chosen from over one thousand synthesized molecules for its ability to specifically and potently block the lymphocyte function-associated antigen-1/intercellular adhesion molecule (LFA-1/ICAM-1) interaction, a validated target in the chronic dry eye inflammatory cycle central to T-cell activation, proliferation, migration, and inflammatory cytokine release at sites of ocular surface stress.   Lifitegrast was engineered to provide good penetration into target periocular tissues, but low absorption into the systemic circulation, allowing for local delivery while minimizing adverse side effects. The molecule is also highly soluble in water, permitting easy formulation into an ophthalmic solution. Lifitegrast ophthalmic solution is unpreserved and is administered in a single-use unit-dose vial.

Lifitegrast has been studied in over 900 subjects to date and has demonstrated statistical significance in several signs and symptoms of dry eye disease in some studies .  Dose-dependent improvements were observ
'/>"/>

SOURCE SARcode Bioscience, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Industry Veteran Katrine Bosley Joins Genocea Biosciences Board Of Directors
2. Pressure BioSciences, Inc. to Present at the SeeThruEquity Spring Investor Microcap Forum
3. Neurocrine Biosciences To Present At The 25th Annual Roth Conference
4. HUYA Bioscience Announces Partnership With Shanghai Zhangjiang Biotech Pharmaceutical Base
5. Sangamo BioSciences Announces Presentation At The Barclays Global Healthcare Conference
6. Presage Biosciences Announces Strategic Research Alliance with Celgene Corporation
7. Sangamo BioSciences Announces Presentation At 33rd Annual Cowen And Company Health Care Conference
8. Neurocrine Biosciences To Present At The Cowen And Company 33rd Annual Health Care Conference
9. Dr. Mickey Urdea Joins Pressure BioSciences Board of Directors
10. Dr. Susan Froshauer to join Connecticut bioscience team at CURE
11. Sigma-Aldrich Corporations Sigma Life Science Business to Distribute Worldwide Olink Biosciences Protein Interaction Analysis Technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... FAIRFAX, Va. , Aug. 21, 2014 /PRNewswire/ ... real-time quality and Manufacturing Intelligence , today ... Intelligence Conference. The event will be held Oct. ... Mile, and is designed to showcase the necessity ... use of metrics and Manufacturing Intelligence to gain ...
(Date:8/21/2014)... Professional Compounding Centers of America (PCCA) ... the three best scientific presentations at the sixth ... The Formulating Better Medicines for Children  conference, ... Athens, Greece , includes dozens of poster-style ... which three winners will be selected by a ...
(Date:8/21/2014)... 2014 Asterias Biotherapeutics, Inc. (OTCBB: ASTY), a ... medicine, announced today the appointments of Andrew ("Andy") Arno ... Board of Directors. With these additions, the Asterias Board ... are independent. Andy Arno , 55, ... companies. He is currently Managing Director of Emerging Growth ...
Breaking Medicine Technology:InfinityQS to Host Manufacturing Intelligence Conference in Chicago 2Professional Compounding Centers of America will award top poster-session winners at European Paediatric Formulation Initiative in Athens 2Asterias Biotherapeutics Appoints Two Independent Directors and Announces Completion of Series A Common Stock Distribution 2Asterias Biotherapeutics Appoints Two Independent Directors and Announces Completion of Series A Common Stock Distribution 3Asterias Biotherapeutics Appoints Two Independent Directors and Announces Completion of Series A Common Stock Distribution 4
... I Results Offer Hope of First Highly Effective Drug in ... June 1 Roche announced today results from a Phase ... promising treatment for patients with advanced melanoma whose cancer harbours ... PLX4032 lived for a median of at least six months ...
... Eli Lilly and Company announced today that Phase ... (gemcitabine HCl for injection) to the current standard of ... at three years for women with locally advanced cervical ... commonly diagnosed women,s cancer, and the second most common ...
Cached Medicine Technology:Encouraging First Data on New Targeted Treatment for Patients With Melanoma - the Deadliest Form of Skin Cancer 2Encouraging First Data on New Targeted Treatment for Patients With Melanoma - the Deadliest Form of Skin Cancer 3Encouraging First Data on New Targeted Treatment for Patients With Melanoma - the Deadliest Form of Skin Cancer 4Encouraging First Data on New Targeted Treatment for Patients With Melanoma - the Deadliest Form of Skin Cancer 5Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients 2Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients 3Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients 4Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients 5Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients 6
(Date:8/21/2014)... NV (PRWEB) August 21, 2014 ... Association for Packaging and Processing Technologies. They deliver ... the view into a whole new world of ... engaged attendees, interactive education, and the latest technology ... solutions from exhibitors. This year at Pack Expo ...
(Date:8/21/2014)... 22, 2014 BambooIndustry.com is an internationally ... company has recently unveiled its new collection of elegant ... made for customers who are looking for high quality ... are offered with great savings (up to 29 percent ... access these cheap products. , The company’s bamboo ...
(Date:8/21/2014)... Sterling Heights, MI (PRWEB) August 21, 2014 ... regarding emails informing a taxpayer that their federal tax ... the email domain appears to come from the IRS, ... unsuspecting victims to provide personal and financial information. , ... few years now, an uptick in phishing activity is ...
(Date:8/21/2014)... in the coronary arteries of chronic kidney disease patients ... according to a new study in the Journal ... ). Researchers at the Johns Hopkins Bloomberg School of ... commonly used measures of subclinical atherosclerosis in predicting the ... , Approximately 50 percent of all patients with chronic ...
(Date:8/21/2014)... August 21, 2014 Pulmonary Hypertension ... an Education Forum for PH patients and families ... Pulmonary Hypertension Association – the country’s ... ways to prevent and cure pulmonary hypertension (PH) ... the functioning of the heart and can lead ...
Breaking Medicine News(10 mins):Health News:Absolute I&D Provides Discounted Labor for Pack Expo Chicago 2Health News:Buy Elegant Bamboo Floorings from Internationally Well-known Supplier BambooIndustry.com 2Health News:Beware Of Phony “Tax Payment Rejected” IRS Emails 2Health News:Measuring calcium buildup to predict heart disease in those with chronic kidney disease 2Health News:Pulmonary Hypertension Association Goes On the Road to Houston With an Education Forum for PH Patients and Families to Help Fight Rare Lung Disease 2Health News:Pulmonary Hypertension Association Goes On the Road to Houston With an Education Forum for PH Patients and Families to Help Fight Rare Lung Disease 3
... of acres of farmland affected by last October,s red mud ... threat to a bountiful harvest, not toxic metals. In a ... also describe an inexpensive decontamination strategy using the mineral gypsum, ... note that a dam burst at a factory processing aluminum ...
... espionage agents probing an enemy,s fortifications, scientists are snooping ... that plants use to protect themselves from diseases. The ... natural defenses and enhance the safety and security of ... an article in the current edition of Chemical & ...
... Teenage girls and young women infected with HIV get pregnant ... HIV-negative peers, according to new research led by Johns Hopkins ... on an analysis of records from 181 patients with HIV, ... years, will be published in the Feb. 2 issue of ...
... keep hospital patients safe and continually improve the overall ... figure out a way to get physicians more involved ... patient care make their contributions to improvement efforts essential," ... patient safety expert and co-author of a commentary published ...
... Figures from a recently compiled report for 2009-2010 show ... students made a $6.8 million economic impact in the ... Education Centers. Specifically, AHEC faculty from UofL provided ... a total of $124,363 in living and travel expenses ...
... A targeted delivery combination selectively crosses the tight barrier that ... and bind to brain tumors, a research team led by ... reported in the January issue of the Journal of ... demonstrated that the targeted particles guide payloads to image tumors, ...
Cached Medicine News:Health News:Teens with HIV at high risk for pregnancy, complications 2Health News:More doctors must join nurses, administrators in leading efforts to improve patient safety, outcomes 2Health News:UofL Area Health Education Centers' faculty, students make $6.8 million economic impact 2Health News:UofL Area Health Education Centers' faculty, students make $6.8 million economic impact 3Health News:Targeted particle fools brain's guardian to reach tumors 2Health News:Targeted particle fools brain's guardian to reach tumors 3Health News:Targeted particle fools brain's guardian to reach tumors 4
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: