Navigation Links
SARcode Bioscience Announces Acquisition by Shire US Holdings Inc.
Date:3/25/2013

track record of SARcode, we believe the near-term milestones are attainable, and would result in an excellent venture-level multiple for all investors," he added.   Institutional investors in SARcode Bioscience include Alta Partners, Clarus Venture Partners, Rho Ventures and Sofinnova Ventures.

The ongoing lifitegrast clinical development program includes two pivotal Phase 3 studies, called OPUS-1 and OPUS-2.  The 700-patient OPUS-2 study, which commenced earlier this year, will aim to build on the positive sign and symptom data resulting from OPUS-1. The results from these two studies, along with data from an ongoing year-long safety study called SONATA, will support a planned New Drug Application.

About Lifitegrast

Lifitegrast is an investigational novel small-molecule integrin antagonist that was "purpose-built" to meet several specifications that would make it an ideal dry eye therapy candidate.  It was chosen from over one thousand synthesized molecules for its ability to specifically and potently block the lymphocyte function-associated antigen-1/intercellular adhesion molecule (LFA-1/ICAM-1) interaction, a validated target in the chronic dry eye inflammatory cycle central to T-cell activation, proliferation, migration, and inflammatory cytokine release at sites of ocular surface stress.   Lifitegrast was engineered to provide good penetration into target periocular tissues, but low absorption into the systemic circulation, allowing for local delivery while minimizing adverse side effects. The molecule is also highly soluble in water, permitting easy formulation into an ophthalmic solution. Lifitegrast ophthalmic solution is unpreserved and is administered in a single-use unit-dose vial.

Lifitegrast has been studied in over 900 subjects to date and has demonstrated statistical significance in several signs and symptoms of dry eye disease in some studies .  Dose-dependent improvements were observ
'/>"/>

SOURCE SARcode Bioscience, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Industry Veteran Katrine Bosley Joins Genocea Biosciences Board Of Directors
2. Pressure BioSciences, Inc. to Present at the SeeThruEquity Spring Investor Microcap Forum
3. Neurocrine Biosciences To Present At The 25th Annual Roth Conference
4. HUYA Bioscience Announces Partnership With Shanghai Zhangjiang Biotech Pharmaceutical Base
5. Sangamo BioSciences Announces Presentation At The Barclays Global Healthcare Conference
6. Presage Biosciences Announces Strategic Research Alliance with Celgene Corporation
7. Sangamo BioSciences Announces Presentation At 33rd Annual Cowen And Company Health Care Conference
8. Neurocrine Biosciences To Present At The Cowen And Company 33rd Annual Health Care Conference
9. Dr. Mickey Urdea Joins Pressure BioSciences Board of Directors
10. Dr. Susan Froshauer to join Connecticut bioscience team at CURE
11. Sigma-Aldrich Corporations Sigma Life Science Business to Distribute Worldwide Olink Biosciences Protein Interaction Analysis Technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... Jan. 15, 2014  Zafgen, Inc., a leading biopharmaceutical ... severely obese patients, today announced initial results from ... inhibitor of methionine aminopeptidase 2 (MetAP2), in patients ... genetic obesity.  These results showed improvements in body ...
(Date:1/14/2014)... 14, 2014 InformEx, North America,s ... chemistry, will hold the 30 th edition of its ... Convention Center from January 21-24. (Logo: http://photos.prnewswire.com/prnh/20131028/NY05330LOGO-a ... pharmaceutical, fine chemical and specialty chemical companies will take part ...
(Date:1/14/2014)... Animal Emergency Critical Care, a LifeCentre partner practice, located at 165 ... the first in Loudoun County to receive ... Susan M. Barnes , Medical Director, is a well-seasoned veterinarian of ... Taylor , are avid scuba divers. "As altitude skiers and hikers, ...
Breaking Medicine Technology:Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 2Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 3Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 4Media Advisory: InformEx 2014 Events & Speaker Lineup for 30th Edition Conference in Miami Beach 2Hyperbaric Veterinary Medicine (hvm) Announces Animal Emergency Critical Care Installs A Small Animal Hyperbaric Chamber 2
... March 8, 2012 , Quality of Life ... available treatment fails in two thirds of patients ... Pevion Biotech AG today announced results from a large, ... vulvovaginal candidiasis (RVVC) patients. It is the first time that ...
... Inc. (Nasdaq: BIOD ) today announced that ... will present a corporate update at the ROTH 24th Annual ... 3:00 p.m. Pacific Time (6:00 p.m. Eastern Time). ... Conference will be held March 11-14, 2012, at the ...
Cached Medicine Technology:Pevion Mandated Patient Survey Confirms Disease Burden of Recurrent Vulvovaginal Candidiasis (RVVC) and Indicates Public Health Problem 2Pevion Mandated Patient Survey Confirms Disease Burden of Recurrent Vulvovaginal Candidiasis (RVVC) and Indicates Public Health Problem 3Pevion Mandated Patient Survey Confirms Disease Burden of Recurrent Vulvovaginal Candidiasis (RVVC) and Indicates Public Health Problem 4
(Date:4/18/2014)... Research Institute at Virginia Mason (BRI) recently received a ... metastatic breast cancer reduces both the growth of primary ... have found in models of the disease that blocking ... percent and can keep the tumor from metastasizing or ... comes from the National Cancer Institute of the National ...
(Date:4/18/2014)... This news release is available in French . ... breakthrough could revolutionize surgical practice and regenerative medicine. A ... Molle et Chimie (CNRS/ESPCI Paris Tech) and Didier Letourneur ... and Paris 13), has just demonstrated that the principle ... used in vivo to repair soft-tissue organs and tissues. ...
(Date:4/17/2014)... show signs of chronic inflammation in non-cancerous prostate tissue ... prostate cancer than those with no inflammation, according to ... the Johns Hopkins Kimmel Cancer Center. , The link ... men with so-called high-grade prostate cancer those with ... the presence of the most aggressive and rapidly growing ...
(Date:4/17/2014)... One of the most popular vaccine brands for children ... may be overlooking some cost factors when choosing vaccines, ... expensive option, according to a new study by University ... administer can be driven by numerous factors," says Sheldon ... professor of computer science and of mathematics at the ...
(Date:4/17/2014)... Diego School of Medicine report that older women, plucky ... loss are more likely to be compassionate toward strangers ... in this month,s issue of the International Journal ... associated with better health and well-being as we age, ... the outcomes of individuals whose deficits in compassion put ...
Breaking Medicine News(10 mins):Health News:Benaroya Research Institute evaluates immunology approach to blocking breast cancer 2Health News:Innovative strategy to facilitate organ repair 2Health News:Innovative strategy to facilitate organ repair 3Health News:Chronic inflammation linked to 'high-grade' prostate cancer 2Health News:Chronic inflammation linked to 'high-grade' prostate cancer 3Health News:Study recalculates costs of combination vaccines 2Health News:The ilk of human kindness 2
... of DNA testing and genetic profiling is proving many skeptics wrong. ... tests outweigh consumers, privacy concerns. From dating, through genealogy, to ... health and lifestyle decisions is gaining acceptance. , ... ...
... OBESE MAY CARRY ASTHMA TRAIT , A new study ... carry a specific trait or phenotype that causes them ... not obese with asthma. Researchers from Quebec, Canada compared ... counts, symptom perceptions, BMI/waist circumference, and waist-to-hip ratio of ...
... Aug. 4 The Kansas Health Policy,Authority (KHPA) has ... enable the agency to analyze the cost and effectiveness ... of a data repository and a data analytic,interface (DAI) ... several,state programs. Andy Allison, KHPA,s deputy director and Medicaid ...
... HILL In the budding field of nanotechnology, scientists already ... the University of North Carolina at Chapel Hill have shown ... lead to new and more effective methods for treating cancer ... and obesity. , A team of researchers led by Joseph ...
... to start or continue smoking, researchers say , , MONDAY, Aug. ... appears to have a stronger effect in people who smoke, ... heart attack patients after the attack. It inhibits formation of ... 259 people given Plavix because of coronary conditions found that ...
... 2008 Revenue Increases 36% to $16.9 Million ... Sets Quarterly Record ... MINNEAPOLIS, Aug. 4 ATS Medical, Inc.,(Nasdaq: ATSI ), manufacturer ... results for the,second quarter ended June 28, 2008. Revenue for the ...
Cached Medicine News:Health News:DNA Testing and Genetic Profiles Help Avoid Broken Hearts Polls Reveal 2Health News:DNA Testing and Genetic Profiles Help Avoid Broken Hearts Polls Reveal 3Health News:Chest Journal: August news briefs 2Health News:Kansas Health Policy Authority Awards Thomson Reuters Contract for Health Care Data Integration and Analysis Initiative 2Health News:Kansas Health Policy Authority Awards Thomson Reuters Contract for Health Care Data Integration and Analysis Initiative 3Health News:UNC study: shape, not just size, impacts effectiveness of emerging nanomedicine therapies 2Health News:UNC study: shape, not just size, impacts effectiveness of emerging nanomedicine therapies 3Health News:Blood-Thinner Plavix Works Harder in Smokers 2Health News:ATS Medical Announces Second Quarter Results 2Health News:ATS Medical Announces Second Quarter Results 3Health News:ATS Medical Announces Second Quarter Results 4Health News:ATS Medical Announces Second Quarter Results 5Health News:ATS Medical Announces Second Quarter Results 6Health News:ATS Medical Announces Second Quarter Results 7Health News:ATS Medical Announces Second Quarter Results 8Health News:ATS Medical Announces Second Quarter Results 9Health News:ATS Medical Announces Second Quarter Results 10
... Tosoh Corporation launched the first generation HPLC ... HPLC/723Ghb brought a new level of automation ... forefront of diabetes testing in Japan. Now ... system, the G7 offers advanced automation; stable ...
... , Monoclonal antibody method for HbA1c ... study shows 99% agreement with the HPLC ... on a CV of 2.6%* means ... Standardization Program (NGSP) certified method, as recommended ...
... Maximize your laboratorys ... and enhanced automated workflow ... high-throughput automated workstation now ... and immunoassay with specimen ...
The sole coagulation analyzer in the world that uses a unique dry reagent card....
Medicine Products: