Navigation Links
SARcode Bioscience Announces Acquisition by Shire US Holdings Inc.
Date:3/25/2013

track record of SARcode, we believe the near-term milestones are attainable, and would result in an excellent venture-level multiple for all investors," he added.   Institutional investors in SARcode Bioscience include Alta Partners, Clarus Venture Partners, Rho Ventures and Sofinnova Ventures.

The ongoing lifitegrast clinical development program includes two pivotal Phase 3 studies, called OPUS-1 and OPUS-2.  The 700-patient OPUS-2 study, which commenced earlier this year, will aim to build on the positive sign and symptom data resulting from OPUS-1. The results from these two studies, along with data from an ongoing year-long safety study called SONATA, will support a planned New Drug Application.

About Lifitegrast

Lifitegrast is an investigational novel small-molecule integrin antagonist that was "purpose-built" to meet several specifications that would make it an ideal dry eye therapy candidate.  It was chosen from over one thousand synthesized molecules for its ability to specifically and potently block the lymphocyte function-associated antigen-1/intercellular adhesion molecule (LFA-1/ICAM-1) interaction, a validated target in the chronic dry eye inflammatory cycle central to T-cell activation, proliferation, migration, and inflammatory cytokine release at sites of ocular surface stress.   Lifitegrast was engineered to provide good penetration into target periocular tissues, but low absorption into the systemic circulation, allowing for local delivery while minimizing adverse side effects. The molecule is also highly soluble in water, permitting easy formulation into an ophthalmic solution. Lifitegrast ophthalmic solution is unpreserved and is administered in a single-use unit-dose vial.

Lifitegrast has been studied in over 900 subjects to date and has demonstrated statistical significance in several signs and symptoms of dry eye disease in some studies .  Dose-dependent improvements were observ
'/>"/>

SOURCE SARcode Bioscience, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Industry Veteran Katrine Bosley Joins Genocea Biosciences Board Of Directors
2. Pressure BioSciences, Inc. to Present at the SeeThruEquity Spring Investor Microcap Forum
3. Neurocrine Biosciences To Present At The 25th Annual Roth Conference
4. HUYA Bioscience Announces Partnership With Shanghai Zhangjiang Biotech Pharmaceutical Base
5. Sangamo BioSciences Announces Presentation At The Barclays Global Healthcare Conference
6. Presage Biosciences Announces Strategic Research Alliance with Celgene Corporation
7. Sangamo BioSciences Announces Presentation At 33rd Annual Cowen And Company Health Care Conference
8. Neurocrine Biosciences To Present At The Cowen And Company 33rd Annual Health Care Conference
9. Dr. Mickey Urdea Joins Pressure BioSciences Board of Directors
10. Dr. Susan Froshauer to join Connecticut bioscience team at CURE
11. Sigma-Aldrich Corporations Sigma Life Science Business to Distribute Worldwide Olink Biosciences Protein Interaction Analysis Technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... N.J. and DETROIT , April ... five children live in poverty, the infant mortality rate is ... at 15 per 1,000 live births. Nearly 6 of 10 ... not receive adequate prenatal care.  These are sobering statistics that ... serving the people of Metro Detroit, is poised to change ...
(Date:4/17/2015)... April 17, 2015 Today, the Pharmaceutical ... employees from 12 biopharmaceutical companies as "We Work ... policy advocacy and community service. Established ... Awards were created by the biopharmaceutical industry to ... their careers, but have also shown an outstanding ...
(Date:4/17/2015)... 17, 2015 Sigma-Aldrich Corporation ... and High Technology company, today announced the opening ... headquarters and state-of-the-art Cell Culture Technical Center in ... will provide customized support to meet customer needs, ... "Our new Technical Center will significantly enhance ...
Breaking Medicine Technology:Covenant Community Care to Receive Donated SONIMAGE P3 Handheld Ultrasound from Konica Minolta Medical Imaging 2Covenant Community Care to Receive Donated SONIMAGE P3 Handheld Ultrasound from Konica Minolta Medical Imaging 3Covenant Community Care to Receive Donated SONIMAGE P3 Handheld Ultrasound from Konica Minolta Medical Imaging 4PhRMA Applauds 2015 We Work For Health Champion Award Winners 2PhRMA Applauds 2015 We Work For Health Champion Award Winners 3Sigma-Aldrich Expands Customer-Centric Model with Investments in Singapore That Localize World-Class Capabilities to Better Support Customers in Asia 2Sigma-Aldrich Expands Customer-Centric Model with Investments in Singapore That Localize World-Class Capabilities to Better Support Customers in Asia 3Sigma-Aldrich Expands Customer-Centric Model with Investments in Singapore That Localize World-Class Capabilities to Better Support Customers in Asia 4Sigma-Aldrich Expands Customer-Centric Model with Investments in Singapore That Localize World-Class Capabilities to Better Support Customers in Asia 5
... HUYA Bioscience International, a company at the ... strategic partnership with the School of Pharmaceutical Sciences at ... foothold in Southern China, aiming to accelerate the development ... The agreement provides HUYA with access to ...
... a pharmacy buying group advancing the growing buying power ... three-year prime vendor agreement with H. D. Smith, a ... with the programs and services available to our members ... the growth and identity of our organization," said Emmanuel ...
Cached Medicine Technology:HUYA Biosciences Establishes Strategic Partnership with Sun Yat-sen University's School of Pharmaceutical Sciences 2HUYA Biosciences Establishes Strategic Partnership with Sun Yat-sen University's School of Pharmaceutical Sciences 3Nigerian Association of Pharmacists and Pharmaceutical Scientists in America (NAPPSA) Announces Prime Vendor Agreement with H. D. Smith 2
(Date:4/17/2015)... Texas (PRWEB) April 17, 2015 From the ... years ago, the Texas non-profit organization has empowered young people ... its effort to bring fresh water and the Gospel ... with Liberty University. Between March 17 and 27, students, faculty ... provide 7,000 Liberians with fresh water and the Good News ...
(Date:4/17/2015)... Rapids, MI (PRWEB) April 17, 2015 Enthusiasts ... CRUSH Grand Rapids, Saturday, April 25, 2015. The event will ... Reserve Wine & Food (201 Monroe Ave NW, Grand Rapids, ... from around the West Michigan area. Patrons are encouraged to ... of elegance and fun. , This year’s event will feature ...
(Date:4/17/2015)... April 17, 2015 Testosterone treatment ... class of prescription medications increases the likelihood that ... or other life-threatening cardiovascular event continue to mount ... Court, Northern District of Illinois. According to an ... Panel on Multidistrict Litigation (JPML) on April 15th, ...
(Date:4/17/2015)... 2015 The American College of Traditional Chinese Medicine ... Day on April 29. The event will be held from 11 ... 555 DeHaro St. in San Francisco, CA. , The agenda for ... at the DeHaro campus (room F), 11:10 a.m. – Introduction ... – Light lunch with current students, faculty and staff, 1 p.m. ...
(Date:4/17/2015)... Carolina (PRWEB) April 17, 2015 With ... Dental Care has spent the last four years ... care, performing procedures ranging from general cleanings to dental ... a grand opening at their new office in North ... same services as their Concord office, including denture fittings, ...
Breaking Medicine News(10 mins):Health News:The Last Well and Liberty U’s TEN Initiative raises $21,000 to Bring Fresh Water & The Gospel to 7,000 Liberians 2Health News:Children’s Leukemia Foundation of Michigan Presents 3rd Annual CRUSH Grand Rapids 2Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 2Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 3Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 4Health News:American College of Traditional Chinese Medicine Hosts Open House 2
... , WASHINGTON, Nov. 24 New peer-reviewed data finding ... infected with chronic hepatitis C virus have received anti-viral therapy ... needs to move urgently on bipartisan legislation to support new ... Hepatitis Roundtable (NVHR) said today. , The ...
... study by researchers from Virginia Commonwealth University Medical Center ... fatty acids (PUFA) is associated with the progression of ... The study also found significantly higher plasma monounsaturated ... and NASH. Full findings appear in the December ...
... be on the hook for the high cost of drug advertising ... led by a University of British Columbia health policy researcher. ... Medicine , examined the US sales patterns of clopidogrel, a top-selling ... blood clots after heart attack or stroke. The drug was selected ...
... , American College of Medical Genetics ... National Family History Day, Thanksgiving 2009 , BETHESDA, Md., ... Family History Day, as declared by the U.S. Surgeon General. ... know their family medical history and if they haven,t already ...
... , HATBORO, Pa., Nov. 23 InfoLogix, Inc. ... enterprise mobility solutions for the healthcare and commercial industries, ... Managed Services at Siemens Health Services, has joined InfoLogix ... http://www.newscom.com/cgi-bin/prnh/20090618/NE35135LOGO ) , As Vice President of ...
... of arsenic compounds appears to cause oxidative DNA damage ... study published online November 23 in the Journal ... was once believed to detoxify inorganic arsenic, it is ... carcinogenicity. To assess the role of ...
Cached Medicine News:Health News:NVHR: New Data Finding Fewer than 1 in 5 Hepatitis C Patients Receiving Antiviral Therapy is 'Wake-Up Call' for Washington 2Health News:NVHR: New Data Finding Fewer than 1 in 5 Hepatitis C Patients Receiving Antiviral Therapy is 'Wake-Up Call' for Washington 3Health News:Metobolomics uncovers key indicators of nonalcoholic fatty liver disease 2Health News:Drug ads ineffective for boosting sales, could cost taxpayers: UBC-Harvard study 2Health News:'Family Health History and Genetics Privacy' is the Newest Addition to the ACMG Genetics & Your Health Video Series 2Health News:Jim Way, Former Vice President at Siemens Health Services, Joins InfoLogix, Inc. as Vice President of Strategic Healthcare Services 2Health News:Jim Way, Former Vice President at Siemens Health Services, Joins InfoLogix, Inc. as Vice President of Strategic Healthcare Services 3
Lacrimal Cannula, Curved - Open End, 21gSize: 21g x 1-1/2"....
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Medicine Products: