Navigation Links
SARS Vaccine Achieves Neutralizing Responses in First U.S. Human Trial
Date:12/9/2008

id Vijay Samant, Vical's President and Chief Executive Officer. "With the data from this successful Phase I trial and control of the IND, we are prepared to advance this vaccine quickly in the event of another outbreak. In the meantime, we can look to the model established with this program in addressing other emerging infectious diseases."

Side effects in the Phase I trial were typically mild, and no serious adverse events were reported. SARS-specific neutralizing antibody responses were detected in 8 of 10 subjects. SARS-specific CD4+ T-cell responses were detected in all 10 subjects, and CD8+ T-cell responses were detected in 2 of 10 subjects. Neutralizing antibody responses are important in preventing infection. CD4+ T cells help direct the appropriate immune resources against specific pathogens. CD8+ T cells find and kill infected cells and are important in clearing virus after infection.

About SARS

Following the initial cases of SARS, identified in the Guangdong Province of China in late 2002, the disease spread rapidly through the summer of 2003 and reached epidemic status, affecting more than 8,000 and killed more than 900 people in 25 countries before it was contained. SARS affects the respiratory system and gastrointestinal tract as well as other internal organs, with particular risk to the elderly and immunocompromised. Healthy adults may become infected and spread the disease without exhibiting any symptoms.

About DNA Vaccines

DNA vaccines may offer both technical and economic advantages compared with conventional vaccine approaches. DNA vaccines encode certain proteins associated with a target pathogen, rather than using any part of the pathogen itself, and can prime the immune system as well as induce antibody and T-cell immune responses. DNA vaccines contain no viral particles, are non-infectious, and can be administered on a repeat basis without unwanted imm
'/>"/>

SOURCE Vical Incorporated
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Two New Studies in the New England Journal of Medicine Show Malaria Vaccine Candidate Advancing in Africa
2. Novavax Announces Preclinical Data for Respiratory Syncytial Virus Vaccine Candidate
3. Wyeth Submits European Marketing Authorization Application for its 13-Valent Vaccine for the Prevention of Pneumococcal Disease in Infants and Young Children
4. The Government of Canada Procures IMVAMUNE(R) Smallpox Vaccine for the Countrys Biological Preparedness
5. GeoVaxs Phase 2a HIV/AIDS Vaccine Human Trials to Begin in North and South America
6. Vical Receives Milestone Payment from Merck & Co., Inc. Triggered by Planned Initiation of Investigational Cancer DNA Vaccine Trial
7. Vical Completes Enrollment and Reports Positive Interim Data in CMV Vaccine Phase 2 Trial
8. Video: Novartis Vaccines and PTA Battle Flu: Public Health Vaccination Initiative Urges Families Lets Fight Flu Together!
9. U.S. Navy and U.S. Army to Develop Dengue DNA Vaccine Formulated With Vicals Vaxfectin(R) Adjuvant
10. MedImmune Advances Pediatric Disease Prevention Program With Start of Phase 1/2a Clinical Trial for Respiratory Syncytial Virus Vaccine
11. Nventa Presents Findings on Proprietary Toll-like Receptor 3 (TLR3) Agonist, Poly-ICR, at World Vaccine Congress
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... , July 14, 2014  GenSpera, Inc. ... for the treatment of cancer, announces that Kareg ... , has issued the following research report on  ... Traube , Director of Research, Kareg Corporation, Initiating ... Read the full report: http://www.genspera.com/press/140711_Genspera_research_report_July2014.pdf ...
(Date:7/14/2014)... Calif. , July 14, 2014 /PRNewswire/ ... announces a technology partnership with global bioengineering ... its technology for quick-to-market products. ... and DNA2.0,s machine learning optimization technologies, such ... up the process of engineering proteins in ...
(Date:7/14/2014)... Ltd. (NASDAQ: SVA ), a leading provider of biopharmaceutical products ... its 2014 Annual Meeting of Shareholders on Wednesday, August 27, 2014 at ... Shangdi Xi Road, Haidian District, Beijing , PRC. All ... vote and are invited to attend. The primary agenda of ... Yuk Lam Lo , Simon Anderson , Kenneth Lee ...
Breaking Medicine Technology:Kareg Corporation Initiates Coverage on GenSpera with a Speculative Buy Recommendation 2Kareg Corporation Initiates Coverage on GenSpera with a Speculative Buy Recommendation 3Kareg Corporation Initiates Coverage on GenSpera with a Speculative Buy Recommendation 4Kareg Corporation Initiates Coverage on GenSpera with a Speculative Buy Recommendation 5Kareg Corporation Initiates Coverage on GenSpera with a Speculative Buy Recommendation 6Pareto Biotechnologies Announces Technology Partnership With DNA2.0, Inc. 2Pareto Biotechnologies Announces Technology Partnership With DNA2.0, Inc. 3Sinovac Schedules 2014 Annual Meeting of Shareholders 2Sinovac Schedules 2014 Annual Meeting of Shareholders 3
(Date:7/14/2014)... July 14, 2014 BCC Research ... SYNTHETIC BIOLOGY: GLOBAL MARKETS , the global ... nearly $11.9 billion in 2018, with a five-year ... products account for the fastest growing segment, with ... Synthetic biology-enabled products in the pharmaceutical/diagnostics, chemical, energy, ...
(Date:7/14/2014)... The Encino cosmetic dentist at Encino ... and porcelain veneers. These restorations are an excellent alternative ... greater loss of healthy tooth tissue. They work similarly ... on the tooth. Encino dentist Dr. Mastour and his ... they offer the most appropriate treatment recommendations for each ...
(Date:7/14/2014)... Gray HealthDay Reporter ... suggests that a faltering sense of smell might signal ... inexpensive, low-tech smell test could spot who needs more ... the decreased ability to identify odors was associated with ... Alzheimer,s disease. "We,re trying to be able to ...
(Date:7/14/2014)... HealthDay Reporter MONDAY, July ... linked to multiple health issues, but dementia isn,t one of ... widowhood may even delay dementia, the researchers found. "For ... was associated with a later age of developing full-blown dementia ... Bryan Woodruff. Woodruff, an assistant professor of neurology ...
(Date:7/14/2014)... Skin M.D. by ... on Monday, July 14th, located at 45 East ... last all week through Saturday, July 19th, with ... welcomed to attend. The business is owned by ... anti-aging, weight loss services, and sells high-end industry ...
Breaking Medicine News(10 mins):Health News:Global Market for Synthetic Biology to Reach Nearly $11.9 Billion by 2018 — Enabled Products Account for the Fastest Growing Segment with 36.7% CAGR 2Health News:Global Market for Synthetic Biology to Reach Nearly $11.9 Billion by 2018 — Enabled Products Account for the Fastest Growing Segment with 36.7% CAGR 3Health News:Encino Esthetic Dental Group is Now Offering Lumineers and Porcelain Veneers 2Health News:Could a Simple Smell Test Help Spot Alzheimer's Early? 2Health News:Could a Simple Smell Test Help Spot Alzheimer's Early? 3Health News:Widowhood May Delay Dementia in Some Seniors, Study Finds 2Health News:Widowhood May Delay Dementia in Some Seniors, Study Finds 3Health News:The Cosmetic Medic Announces Grand Opening of New Skin M.D., a Physician-Administered Anti-aging, Skincare, and Weight Loss Practice 2Health News:The Cosmetic Medic Announces Grand Opening of New Skin M.D., a Physician-Administered Anti-aging, Skincare, and Weight Loss Practice 3
... hunger strike to protest against the raising of the Narmada ... attending on her Sunday. // ,"Medha Patkar has ... doctor at the All India Institute of Medical Sciences (AIIMS) ... ,AIIMS medical superintendent D.K. Sharma said that Patkar's ...
... strapped for cash are planning on letting go of staff and ... Hospital in Wolverhampton, a hospital in such a crisis which has ... hoping to save about ?2.5 million a year. The management hope ... medical secretary bill by sending voice recordings over the internet to ...
... a Melbourne study australians go to hospitals with injuiries due ... latest issue of the Medical// Journal of Australia. ... to falls of all hospital cases. ,Associate Professor ... Centre led the study and incorporated a falls prevention ...
... diet can influence corrective behaviour in prisoners.// ... product of poor nutrition was tested in a prison ... less violent when put on a diet rich in ... paper titled “Seafood Consumption and Homicide Mortality”, raised this ...
... UK has fallen to its lowest levels since such records ... Suicide Prevention Strategy. The report also shows //a drop in ... well as a decline in the number of suicides among ... major cause of preventable death in England and elsewhere. At ...
... chemicals that could trigger inflammation leading to deterioration of ... the crucial link between obesity and heart disease. ... that fat cells lying close to blood vessels in ... influence biological processes within the body, reported the online ...
Cached Medicine News:
... A surgically implanted bone growth stimulator ... EBI OsteoGen surgically implanted bone growth stimulator ... of nonunions when surgery is already planned ... concern. Because the OsteoGen is totally surgically ...
... contact between grant material and fracture ends ... bones., ,Grid-Like Format of Mesh Cathode Provides ... , ,The innovative Mesh Cathode of the ... and a scaffolding effect designed to increase ...
... Cystoscope System using EndoSheath Technology introduces ... urologists in both their hospitals and ... flexible cystoscope with the sterile, protective ... procedures, while minimizing the costs of ...
... Plasma-CISE™ (wire electrodes) and Plasma-CUT™ ... devices that produce precise, consistent ... spread and Vapor sealing of ... The devices provide excellent results ...
Medicine Products: