Navigation Links
S1 Biopharma Doses First Patients in Phase 2a Clinical Trial of Lorexys in Premenopausal Women with HSDD
Date:7/29/2013

JERSEY CITY, N.J., July 29, 2013 /PRNewswire/ -- S1 Biopharma, Inc., a developer of first-in-class drugs for sexual dysfunction in women and men, today announced enrollment and dosing of premenopausal women with hypoactive sexual desire disorder (HSDD) in the Phase 2a clinical trial of its leading drug candidate Lorexys (S1P-104).  

"The initiation of this study marks a significant milestone for S1 Biopharma as we advance Lorexys' clinical development," said Nicolas G. Sitchon, chief executive officer of S1 Biopharma. "Despite significant effort over many years, there are no FDA-approved treatments for women with HSDD. We believe Lorexys may provide the first safe and effective treatment option for those whose lives and the lives of their partners are affected by the disorder. By restoring the balance of the key neurotransmitters that regulate sexual desire in the brain we expect that Lorexys will help women with sexual desire and arousal disorders regain a healthy sexual life."

The leading scientific model of the regulation of sexual desire in the brain is the Kinsey dual control model. It explains that sexual inhibition and sexual excitation are kept in balance by activating and inhibiting neurotransmitters including serotonin, norepinephrine and dopamine.

"Lorexys, which is a first-in-class drug for HSDD, was formulated by identifying the two psychiatric medications, bupropion and trazodone, that, when combined in a precise, proprietary ratio, would modulate the activity of these neurotransmitters, neutralize the monoamine modulators' side effects and maximize beneficial effects on sexual function," said Robert E. Pyke, M.D., Ph.D., chief medical officer of S1 Biopharma. "Pilot data supported positive effects, unlike other serotonergic agents or combinations studied in our early drug development. S1P-205,
'/>"/>

SOURCE S1 Biopharma, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Biopharma M&A Trends Hold Steady, But Deals Declined in 2011
2. Enox Biopharma, Inc. To Present Today At IN3 Medical Device 360 Conference In London
3. Alder BioPharmaceuticals Inc. Initiates Phase 1 Clinical Study of Antibody Therapeutic Candidate for Treatment of Migraine, ALD403
4. Keryx Biopharmaceuticals, Inc. To Host Conference Call on First Quarter 2012 Financial Results
5. Genesis Biopharma Announces Termination of Previously Announced Proposed Public Offering
6. Keryx Biopharmaceuticals, Inc. Announces First Quarter 2012 Financial Results
7. S1 Biopharma Expands Focus to Include Male Sexual Health
8. New Study Details Foreign Efforts To Lure Biopharmaceutical Companies
9. Keryx Biopharmaceuticals Announces Upcoming Poster Presentation of Zerenex™ (ferric citrate) at the 49th ERA-EDTA Congress
10. Cell Therapeutics Aequus BioPharma Validates its Proprietary GlycoPolymer Technology for the Extension of the Half-life of Therapeutic Protein Drugs
11. Galena Biopharma, Inc. Investor Presentation Now Available for On-demand Viewing at RetailInvestorConferences.com
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... -- Edwards Lifesciences Corporation (NYSE: EW ), the ... hemodynamic monitoring, announced that Edwards, Chairman and CEO ... panelist at the invitation of the United States Energy ... device innovation at its hearing, "21 st Century ... "Edwards has five decades of experience in ...
(Date:7/22/2014)...  Decision Resources Group finds that the market for interventional ... remain relatively stagnant at a value of around $80 million ... intervention (PCI) volumes are growing faster in Canada ... the United States and Europe ... increase in penetration of PCI procedures relative to coronary artery ...
(Date:7/22/2014)... July 22, 2014 The number of people ... people each day. Twenty-three percent of the workforce has ... Drug Use and Health, making opioid use a serious ... opioid painkillers at the correct dosage with a valid ... Today, the National Safety Council released a ...
Breaking Medicine Technology:Edwards' CEO Invited To Address Congress On Opportunities To Revitalize Medical Device Innovation 2The Canadian Interventional Cardiology Device Market Will Remain Relatively Stagnant Through 2022 at Around $80 Million 2The Canadian Interventional Cardiology Device Market Will Remain Relatively Stagnant Through 2022 at Around $80 Million 35 things employers should know about prescription painkiller use 25 things employers should know about prescription painkiller use 3
... Pharmasset, Inc. (Nasdaq: VRUS ) announced today ... trial of PSI-7977, a nucleotide analog polymerase inhibitor, for ... and consistent antiviral effects and high barrier to resistance ... additional exploratory regimens in this setting.  This amendment will ...
... 8, 2011 Reportlinker.com announces that ... available in its catalogue: ... Pipeline Analysis,Competitive Landscape and Market Forecasts ... http://www.reportlinker.com/p0490348/Hip-Resurfacing-Implants---Global-Pipeline-AnalysisCompetitive-Landscape-and-Market-Forecasts-to-2017.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=Orthopedic Hip Resurfacing ...
Cached Medicine Technology:Pharmasset Announces the Expansion of the ELECTRON Trial in Chronic Hepatitis C 2Pharmasset Announces the Expansion of the ELECTRON Trial in Chronic Hepatitis C 3Pharmasset Announces the Expansion of the ELECTRON Trial in Chronic Hepatitis C 4Hip Resurfacing Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 2Hip Resurfacing Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 3Hip Resurfacing Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 4Hip Resurfacing Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 5Hip Resurfacing Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 6Hip Resurfacing Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 7Hip Resurfacing Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 8Hip Resurfacing Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 9Hip Resurfacing Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 10Hip Resurfacing Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 11Hip Resurfacing Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 12Hip Resurfacing Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 13
(Date:7/23/2014)... TeraGanix has recently announced the opening of ... 4.5 miles off of highway I-8. The new production center ... businesses in the Arizona region that use its popular ... Grande location is only 1 hour away from Tucson, 2 ... With over 26 million acres of agricultural land in ...
(Date:7/23/2014)... There is inherently nothing wrong with sweating. When ... enough to react to specific changes in the environment. ... and bacteria from the body in ways that the ... , However, the social implications for people who ... sweating”—are serious: since sweating itself often causes instances of ...
(Date:7/23/2014)... (PRWEB) July 23, 2014 Temecula ... “Twelve Temecula Valley Southern California Wine Country artisan ... days and two nights genuinely nourishing. Savor like ... Mountain, Palumbo, and Vindemia wineries; EAT Marketplace, Palumbo’s ... and Temecula Olive Oil,” announced Kimberly Adams, president ...
(Date:7/23/2014)... Olympia, WA (PRWEB) July 23, 2014 ... today announced that their leading IBM i security solutions ... organizations to reduce the security weakness of relying on ... now leverage Townsend Security’s mobile-based Alliance Two Factor ... the IBM i., , Alliance AES/400 ...
(Date:7/23/2014)... July 23, 2014 Once viewed with ... practice, hospice has become a $14 billion-a-year business and ... America. In Changing the Way We Die , ... hospice means to today’s aging population and their families. ... at the hospice landscape, reporting the stories of patients, ...
Breaking Medicine News(10 mins):Health News:TeraGanix Opens New Arizona-Based Agricultural Products Supply Facility 2Health News:TeraGanix Opens New Arizona-Based Agricultural Products Supply Facility 3Health News:Beat Your Sweating Demons Review | The Problem With Excessive Sweating and Solving it Naturally – Vinamy.com 2Health News:Beat Your Sweating Demons Review | The Problem With Excessive Sweating and Solving it Naturally – Vinamy.com 3Health News:12 Artisan Food and Wine Experiences in Temecula Valley Southern California Wine County 2Health News:12 Artisan Food and Wine Experiences in Temecula Valley Southern California Wine County 3Health News:12 Artisan Food and Wine Experiences in Temecula Valley Southern California Wine County 4Health News:Townsend Security Brings Two Factor Authentication to Leading IBM i Security Solutions 2Health News:Dealing with Loss: Library Journal Calls Changing the Way We Die an Essential Read 2
... on fake IDs mean fewer fatalities on the road , , ... drinking have reduced the rate of drunk-driving deaths in the ... by the Substance Abuse Policy Research Program of the Robert ... illegal to possess or purchase alcohol under the age of ...
... CINCINNATIA new review of studies from the University of ... workplace may actually be the ticket to dropping weight. ... UC, employer-based programs for weight loss are modestly effective ... "Worksite-based programs do tend to result in weight loss ...
... News, Physicians, Blog, Clinical Study Analysis ... and Evidence-Based Treatment ... for Cardiovascular,Angiography and Interventions (SCAI), the leading professional ... site at, http://www.Seconds-Count.org with a new section ...
... Barona Valley Ranch Resort and Casino Ranks Highest in Satisfaction ... the Casino Experience in ... large majority -- 85,percent -- of gaming customers at Indian ... environment in these casinos,according to the J.D. Power and Associates ...
... University and VCU Massey Cancer Center researchers have ... (mda-7/IL-24), induces a bystander effect that kills cancer ... ones, a discovery that could lead to new ... The findings may provide a method to target ...
... child has,filed a class action lawsuit against Blue Cross Blue ... Sean Cox in Federal Court. Mr. Chris,Johns alleges that the ... The suit alleges that Blue Cross is required to,provide coverage ... that it,has not done so in bad faith and in ...
Cached Medicine News:Health News:Tough Underage Drinking Laws Saving Lives 2Health News:Tough Underage Drinking Laws Saving Lives 3Health News:UC research shows employer-based weight loss programs are helpful 2Health News:Expanded Seconds-Count.org Helps Physicians Navigate Spectrum of Cardiovascular Disease Treatment Options 2Health News:Expanded Seconds-Count.org Helps Physicians Navigate Spectrum of Cardiovascular Disease Treatment Options 3Health News:J.D. Power and Associates Reports: A Vast Majority of Southern California Indian Gaming Casino Customers Express Desire for a Smoke-Free Environment 2Health News:J.D. Power and Associates Reports: A Vast Majority of Southern California Indian Gaming Casino Customers Express Desire for a Smoke-Free Environment 3Health News:J.D. Power and Associates Reports: A Vast Majority of Southern California Indian Gaming Casino Customers Express Desire for a Smoke-Free Environment 4Health News:Discovery of gene mechanism could bring about new ways to treat metastatic cancer 2
... Arctic Circler uses the same cryoconsole ... AF originating in the pulmonary veins. Arctic ... challenge the traditional palliative-only treatments that rely ... the Arctic Circler catheter has the ability ...
... The Guglielmi Detachable Coil is intended for: ... because of,their morphology, their location, or the ... by the treating,neurosurgical team to be a) ... operative techniques, or b) inoperable.,The GDC is ...
Care must be taken to operate the power unit slowly to help eliminate the possibility of breaking the wires by over-tightening....
Large solid mallet with patented Ortho-Grip® silicone rubber handle....
Medicine Products: