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Rules-Based Medicine Forms Biomarker Alliance With Covance Inc.
Date:11/18/2009

rate their drug development programs."

RBM's Multi-Analyte Profile (MAP) test panels measure from a few to several hundred protein biomarkers involved in numerous biochemical pathways from a single drop of fluid. MAPs provide a comprehensive, reliable and cost-effective means of measuring protein expression patterns. A typical customer will follow the "RBM Approach" and use a large immunoassay MAP, such as DiscoveryMAP(TM), in early clinical research. As the project matures, the customer will select stratification, safety and efficacy biomarkers to create a targeted panel, or CustomMAP, that is suitable for use in late-stage clinical trials.

About Rules-Based Medicine, Inc.

Rules-Based Medicine (RBM) is a CLIA-certified biomarker testing laboratory that solves complex therapeutic development, diagnostic and treatment challenges with innovative products and services. The Company's proprietary Multi-Analyte Profiling (MAP) platform makes the drug discovery and development process more efficient and effective by providing pre-clinical and clinical researchers with reproducible, quantitative, multiplexed immunoassay data for hundreds of proteins from small sample volumes. Building on the MAP platform, RBM has developed a host of solutions including: a self-contained whole-blood culture system that brings reproducibility and simplicity to ex vivo immune response measurement; novel and companion diagnostic tests for complex diseases and therapies; therapeutic-specific MAPs custom designed for late-stage clinical development; and new assays for the early detection of renal damage. More information about RBM is available via the worldwide web at www.rulesbasedmedicine.com.

About Covance Inc.

Covance, with headquarters in Princeton, New Jersey, is one of the world's largest and most comprehensive drug development services
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SOURCE Rules-Based Medicine, Inc.
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