Navigation Links
Rotigotine Transdermal System Shows Significant Symptom Reduction and Tolerability in Patients with Restless Legs Syndrome
Date:10/8/2007

cally relevant reduction in the CGI Item-1 (severity of

illness) score compared to placebo

* The mean baseline scores were: IRLS 23.3 plus or minus 5.0 and CGI 4.7

plus or minus 0.7, reflecting moderate-to-severe symptoms at baseline

* The net effects over placebo after six months of treatment were -2.2

plus or minus 1.2, -2.3 plus or minus 1.2, -4.5 plus or minus 1.2

(p<0.001), -5.2 plus or minus 1.2 (p<0.001) in the IRLS and -0.35 plus

or minus 0.19, -0.32 plus or minus 0.19, -0.65 plus or minus 0.19

(p<0.001), -0.90 plus or minus 0.19 (p<0.001) in CGI Item-1 for

rotigotine 0.5, 1, 2, and 3 mg/24 hours respectively

* Rotigotine was also shown to be generally well-tolerated

* The most common adverse events were application site reactions (27.2%),

nausea (21.5%), headache (17.6%) and somnolence (12.6%)

24-Month, Open-Label Extension Trial in RLS

SP 710

* In an open-label extension of a double-blind, placebo-controlled, Phase

II dose-finding study conducted at multiple centers in Europe,

rotigotine, administered with optimal dose titration, showed long-term

therapeutic efficacy in patients with moderate-to-severe idiopathic RLS

who were treated for 24 months

* A total of 295 patients entered the open-label extension trial and 191

(65%) completed the two-year maintenance period of this ongoing trial

* After 24 months of open-label rotigotine treatment, 87% of patients were

rated as only mildly ill, borderline symptomatic, or normal on the CGI

Item-1 scale which rates overall severity of illness

* The "change of condition" CGI Item-2 score showed a sustained

improvement from the beginning through to the 24th month of open-label

maintenance

* Additionally, the "severity at bedtime falling asleep" score (RLS-6 Item

2) improved by 4.0 plus or minus 3.1 p
'/>"/>

SOURCE UCB, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment
2. NuPathe Reports Positive Phase One Results for NP101 Transdermal Therapy for Acute Migraine
3. Daytrana (methylphenidate transdermal system) Provides Significant Effectiveness in ADHD Symptom Relief in Both Boys and Girls
4. 12-Month Study Demonstrated Tolerability and Efficacy of DAYTRANA (methylphenidate transdermal system)
5. Phosphagenics to Commence Phase 1b Transdermal Insulin Clinical Trial in Second Quarter
6. When Volume Matters, Immunoassay Systems Deliver
7. Genetic Analysis Systems Enter the Clinical Mainstream
8. New Quality Control Systems for Every Laboratory Application
9. Immunoassay Systems - Your Laboratory Workhorse
10. Gene Therapy Eradicates Pancreatic Cancer in Preclinical Trial Targeting Systems Success in Mouse Model Reported in Cancer Cell
11. Researchers Discover Method for Identifying How Cancer Evades the Immune System
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... , July 11, 2014 The consumer ... evolving across industry sectors to better identify winning ... ways to engage with and understand consumers, as ... and make critical purchasing decisions. ... Practices, LLC, one area where organizations can observe ...
(Date:7/11/2014)... July 11, 2014 Research and Markets ... Needles Market 2014-2018" report to their offering. ... hypodermic needle is a hollow needle commonly used with ... or to extract fluids from it. A hypodermic needle ... inject substances that cannot be ingested. Hypodermic needles are ...
(Date:7/11/2014)... 2014 According to a new ... Market (Endoscopes, Endoscopic Operative Devices, and Visualization Systems) - ... 2013-2019" the global endoscopy devices market was valued at ... grow at a CAGR of 6.8% from 2013 to ... billion in 2019. Browse the full Endoscopy ...
Breaking Medicine Technology:New Technologies Transforming Consumer Marketing Research Playbook 2Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 2Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 2Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 5Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 6
... 26, 2011 /PRNewswire-Asia/ -- Neusoft Corporation ("Neusoft", 600718.SH), ... China, recently announced that its wholly-owned subsidiary Neusoft ... agreement with Aerotel Medical Systems Ltd. ("Aerotel"), a ... based telemedicine and telecare solutions based in Israel, ...
... AMSTERDAM, April 25, 2011 Leading events organiser UBM ... postponement of its CPhI, ICSE, P-MEC and BioPh Japan events ... northern Japan, the events have now been rescheduled and will ... Exhibition Centre.  The Japanese business community is intent on picking ...
Cached Medicine Technology:Neusoft to Invest in Israeli Medical Solutions Company for Accelerating Expansion in Global Healthcare Service Market 2Boost For Japanese Pharma Market as UBM Announces Rescheduled Japan Pharma and Bio Events 2Boost For Japanese Pharma Market as UBM Announces Rescheduled Japan Pharma and Bio Events 3
(Date:7/13/2014)... Recently, MyDressCity.com, one of the most popular suppliers ... released its new range of elegant Quinceanera dresses ... at discounted prices. Worldwide clients can enjoy this special ... company’s online shop, there are plenty of beautiful dresses ... great materials. MyDressCity.com’s hot items are prom gowns, bridesmaid ...
(Date:7/13/2014)... A decreased ability to identify odors might ... disease, while examinations of the eye could indicate ... Alzheimer,s, in the brain, according to the results ... Alzheimer,s Association International Conference 2014 (AAIC 2014) in ... decreased ability to identify odors was significantly associated ...
(Date:7/13/2014)... California (PRWEB) July 13, 2014 Celebrity ... Musico has formed a promotional partnership with Aqua Health ... based Omega-3 EPA supplement . The collaboration was ... a celebrity fitness trainer , actor, model, and ... go-to trainer for A-List celebrities, he has prepared stars ...
(Date:7/13/2014)... Wa (PRWEB) July 13, 2014 According ... Vkool.com, this is a comprehensive program that teaches people ... peripheral neuropathy without medications. This program also ... relieving symptoms of peripheral neuropathy , including numbness, prickling, ... in its review that this home treatment program can ...
(Date:7/12/2014)... Recently, Fadhits.com, a well-known wedding dress manufacturer and retailer, has ... to its product line. In addition, the company has ... to bring more benefits for its loyal fans. All ... up to 72% off. , As a leader in the ... shop is a good place for ladies who want to ...
Breaking Medicine News(10 mins):Health News:Cheap Elegant Quinceanera Dresses Unveiled by MyDressCity.com 2Health News:Smell and eye tests show potential to detect Alzheimer's early 2Health News:Smell and eye tests show potential to detect Alzheimer's early 3Health News:Smell and eye tests show potential to detect Alzheimer's early 4Health News:Smell and eye tests show potential to detect Alzheimer's early 5Health News:Smell and eye tests show potential to detect Alzheimer's early 6Health News:Smell and eye tests show potential to detect Alzheimer's early 7Health News:Celebrity Fitness Expert Supports Revolutionary New Health Supplement 2Health News:The Peripheral Neuropathy Program Review Exposes Randall Labrum's Peripheral Neuropathy Treatment Program – Vkool.com 2Health News:The Peripheral Neuropathy Program Review Exposes Randall Labrum's Peripheral Neuropathy Treatment Program – Vkool.com 3Health News:New Collection of Long Graduation Dresses Revealed by Fadhits.com 2
... Pregnant women have a higher incidence of insufficient ... dehydration, according to a study conducted by researchers at Ben-Gurion ... was published in the July issue of Archives of ... study was to determine whether the summer season is a ...
... with highest levels are more apt to have joint replacement, ... of a certain protein strongly predict the risk of hip ... a new study shows. , The research involved 912 healthy ... led to a knee or hip replacement between 1990 and ...
... , , ... Blue Shield of Texas (BCBSTX) joined other Blue Plans today to ... health care cost information tool, developed by WellPoint, which is called ... than 48 million American consumers will have access to valuable cost ...
... Could Solve the Isotope Crisis within 24 months , ... a leading provider of medical isotopes and radiopharmaceuticals, has ... Review Panel on Medical Isotope and Technetium-99m (Tc-99m) Generator ... the shortage of medical radioisotopes is the completion and ...
... patients (three male and seven female) with hepatic angiomyolipoma, ... 19-78 years). Of these patients, dynamic contrast CT showed ... density, absence of a capsule, and prominent central vessels ... with or without a fat component in four cases ...
... , , , ... will report financial results for the second quarter ended June 30, 2009 ... The Company has scheduled a conference call for Thursday, August 6, 2009 ... , Interested parties can access the call by dialing (877) ...
Cached Medicine News:Health News:Summer heat increases risk of amniotic fluid level deficiency, Ben-Gurion University study reveals 2Health News:Biomarker Could Predict Severe Osteoarthritis 2Health News:Blue Cross and Blue Shield of Texas Collaborates With Five Blue Plans to Increase Transparency, Expand Access to Health Care Cost Information 2Health News:MDS Nordion Submits Expression of Interest Proposal to Government of Canada on Medical Isotope and Generator Production 2Health News:MDS Nordion Submits Expression of Interest Proposal to Government of Canada on Medical Isotope and Generator Production 3
The TV-Mag is a 1.9x focusing telescope, used mainly for watching television. It has a large objective lens giving excellent light transmission and a wide field of view....
This 6x or 8x aspheric magnifier is fitted with a distance piece and is particularly useful for patients with tremor or focusing difficulties. The magnifier can be either spectacle mounted or hand h...
The Redi-glaze spectacle magnifier is an aspheric lens, glazed into a standard Keeler LVA frame....
This set offers the full range of Keeler magnifiers and telescopes....
Medicine Products: