Navigation Links
Rotigotine Transdermal System Shows Significant Symptom Reduction and Tolerability in Patients with Restless Legs Syndrome
Date:10/8/2007

- Data Presented at the 132nd Annual Meeting of the American Neurological

Association in Washington, D.C. -

ATLANTA, Oct. 8 /PRNewswire/ -- UCB, Inc. presented results from two Phase III pivotal trials and one open-label extension trial of rotigotine transdermal system for the treatment of moderate-to-severe restless legs syndrome (RLS). These rotigotine data showed significant drops in RLS symptoms, including changes of up to 8 points over placebo using the International Restless Legs Syndrome Study Group Rating Scale (IRLS) and a reduction in disease severity over a two-year period.

"Given the strong efficacy and tolerability seen to date, rotigotine, if approved, would provide a new and valuable alternative for many patients negatively impacted by the symptoms of moderate-to-severe RLS," said Wayne Hening, M.D., a lead study investigator and Assistant Clinical Professor of Neurology at the Robert Wood Johnson Medical School.

In the two six-month, double-blind, placebo-controlled trials, rotigotine produced clinically relevant and statistically significant reductions in RLS symptoms compared to placebo and was generally well-tolerated. An additional presentation highlighted a two-year interim analysis of a long-term, open- label extension of rotigotine for moderate-to-severe RLS, representing some of the longest safety follow-up information for a dopamine agonist in RLS to date.

In these studies, the efficacy of rotigotine was evaluated by monitoring several clinician-administered scales including the IRLS, the Clinical Global Impressions (CGI) and the Restless Leg Syndrome-6 (RLS-6). The IRLS scale measures the severity and frequency of RLS symptoms and the degree to which they affect sleep and daily life (IRLS: 0 = no symptoms and 40 = very severe symptoms). The CGI scale measures the general severity of an illness, clinical improvement or efficacy of treatment parameters. On the RLS-6 scale, patients rate the
'/>"/>

SOURCE UCB, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment
2. NuPathe Reports Positive Phase One Results for NP101 Transdermal Therapy for Acute Migraine
3. Daytrana (methylphenidate transdermal system) Provides Significant Effectiveness in ADHD Symptom Relief in Both Boys and Girls
4. 12-Month Study Demonstrated Tolerability and Efficacy of DAYTRANA (methylphenidate transdermal system)
5. Phosphagenics to Commence Phase 1b Transdermal Insulin Clinical Trial in Second Quarter
6. When Volume Matters, Immunoassay Systems Deliver
7. Genetic Analysis Systems Enter the Clinical Mainstream
8. New Quality Control Systems for Every Laboratory Application
9. Immunoassay Systems - Your Laboratory Workhorse
10. Gene Therapy Eradicates Pancreatic Cancer in Preclinical Trial Targeting Systems Success in Mouse Model Reported in Cancer Cell
11. Researchers Discover Method for Identifying How Cancer Evades the Immune System
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... , Nov. 21, 2014  The University of Maryland,s ... the ceremonial groundbreaking of the new A. James Clark ... new building will cultivate transformative new engineering and biomedical ... Taking place at 10:00 a.m. on November 21 at ... Branch Parking Lot, adjacent to the Jeong H. Kim ...
(Date:11/21/2014)... , Nov. 21, 2014   Rock Creek ... that the Company is scheduled to present at the ... Francisco, CA on January 12-14, 2015. ... and CEO of Rock Creek Pharmaceuticals, will present preclinical ... cholinergic agonist which exhibits anti-inflammatory pharmacological characteristics. Dr. Mullan ...
(Date:11/21/2014)... 2014  PTC Therapeutics, Inc. (NASDAQ: PTCT ) ... Award for Vision, Innovation, and Leadership has been awarded to ... award recognizes an individual who has had a significant impact ... for several decades. "I am honored to ... Peltz , Ph.D., CEO of PTC Therapeutics, Inc. "When I ...
Breaking Medicine Technology:University of Maryland Breaks Ground for A. James Clark Hall 2University of Maryland Breaks Ground for A. James Clark Hall 3University of Maryland Breaks Ground for A. James Clark Hall 4Rock Creek Pharmaceuticals to Present at the Biotech Showcase 2015 2Rock Creek Pharmaceuticals to Present at the Biotech Showcase 2015 3Rock Creek Pharmaceuticals to Present at the Biotech Showcase 2015 4PTC Therapeutics Announces CEO, Dr. Stuart Peltz Recipient of The New Jersey Technology Council's 2014 Legend of Technology Award 2PTC Therapeutics Announces CEO, Dr. Stuart Peltz Recipient of The New Jersey Technology Council's 2014 Legend of Technology Award 3
(Date:11/24/2014)... (PRWEB) November 24, 2014 Recently, SweetDressy.com, ... industry, unveiled its new collection of 2014 Evening Dresses. ... now. According to the company’s marketing manager, the special ... http://www.sweetdressy.com/evening-dresses.html for more. , Sweetdressy.com has been working ... pleased to unveil the latest designs. Their new dresses ...
(Date:11/24/2014)... New York (PRWEB) November 24, 2014 ... contacted by the Family and Children's Association ... such as soap, shampoo, mouthwash and other such items.The ... citizens who are home bound, living in nursing homes, ... intended to greatly enhance the well being of seniors ...
(Date:11/24/2014)... SWAccessControl.com has recently released a new ... fact, the company is a leading online supplier in the ... are available at discounted prices, up to 30% off. , ... locks. This time, all of our items are offered at ... abroad, so I have confidence in our fresh assortment. You ...
(Date:11/24/2014)... Mental health issues affect tens ... up families, ruin careers, and generally destroy lives. ... that suffer,” says Hardy Nutritionals® founder ... our specialized nutritional treatments can reverse these disorders ... Over Matter”, the premiere episode of O2 Media’s ...
(Date:11/24/2014)... TX (PRWEB) November 24, 2014 The ... all of the wrong ingredients. Consistently consuming a diet ... to develop stores of excess fat that typically accumulate ... problems and rearing its ugly head in the form ... , When dieters make the decision to rid themselves ...
Breaking Medicine News(10 mins):Health News:SweetDressy.com Unveiled A New Selection Of Evening Dresses 2Health News:The Holiday Inn Westbury - Long Island gives back to the local Long Island community, and also goes beyond borders to assist those in need during the 2014 Holiday Season 2Health News:The Holiday Inn Westbury - Long Island gives back to the local Long Island community, and also goes beyond borders to assist those in need during the 2014 Holiday Season 3Health News:SWAccessControl.com Is Happy To Release New Range Of Magnetic Locks 2Health News:Nutritional Mental Health Treatment Featured on Access Health Airing on Lifetime Television® 2Health News:Nutritional Mental Health Treatment Featured on Access Health Airing on Lifetime Television® 3Health News:Ketogenic Diet is the Perfect Solution for Diet Doc Patients Who Want to Learn How to Lose Weight over the Holidays 2Health News:Ketogenic Diet is the Perfect Solution for Diet Doc Patients Who Want to Learn How to Lose Weight over the Holidays 3Health News:Ketogenic Diet is the Perfect Solution for Diet Doc Patients Who Want to Learn How to Lose Weight over the Holidays 4
... Net Revenue Increased 93.6% to US$146.5 million; Non-GAAP Gross Margins ... ... 10 /Xinhua-PRNewswire-FirstCall/ -- Mindray,Medical International Limited (NYSE: MR ), a ... selected,unaudited financial results for the third quarter and nine months ended,September ...
... messaging has,rapidly become a favorite form of communication for ... health risk, says the American,Medical Association (AMA) in new ... voted today to advocate for state,legislation prohibiting the use ... while driving takes the driver,s attention away from the ...
... Nov. 10 Immtech Pharmaceuticals,Inc. (Amex: IMM ) ... 30, 2008., For the three months ended September ... the three months ended September 30, 2007.,The decrease was ... Loss from operations for the three months ended,September 30, ...
... (NYSE: HR ) today announced results for the ... per diluted common,share totaled $0.36, compared with $0.31 for ... totaled $1.13 for the nine months ended September,30, 2008, ... been $0.38,and $1.14 per diluted common share for the ...
... before operation leads to more bleeding, longer hospital stay, study ... has taken the clot-preventing drug Plavix less than five days ... bleeding, is more likely to require a second operation, and ... that buttresses current guidelines. , Those guidelines from the American ...
... who want to delay childbirth , , MONDAY, Nov. 10 ... freeze and transplant ovaries, a development that could help ... can transplant ovaries without any loss of ovarian tissue ... fresh or frozen," said co-researcher Dr. Sherman Silber, director ...
Cached Medicine News:Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 2Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 3Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 4Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 5Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 6Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 7Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 8Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 9Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 10Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 11Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 12Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 13Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 14Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 15Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 16Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 17Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 18Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 19Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 20Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 21Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 22Health News:Mindray Announces 2008 Third Quarter and Nine Months Results 23Health News:Immtech Reports Fiscal Second Quarter 2009 Results 2Health News:Immtech Reports Fiscal Second Quarter 2009 Results 3Health News:Healthcare Realty Trust Announces Third Quarter Results 2Health News:Healthcare Realty Trust Announces Third Quarter Results 3Health News:Healthcare Realty Trust Announces Third Quarter Results 4Health News:Healthcare Realty Trust Announces Third Quarter Results 5Health News:Healthcare Realty Trust Announces Third Quarter Results 6Health News:Healthcare Realty Trust Announces Third Quarter Results 7Health News:Healthcare Realty Trust Announces Third Quarter Results 8Health News:Healthcare Realty Trust Announces Third Quarter Results 9Health News:Study Upholds Stopping Plavix Use Before Surgery 2Health News:Freezing Ovaries Preserves Fertility, Scientists Report 2Health News:Freezing Ovaries Preserves Fertility, Scientists Report 3
... Stereo Cube is used to diagnose Stereo and ... use of polarized glasses. The test can ... stereopsis, visual attention, form and depth perception. The ... to 450 seconds of arc and is ideal ...
The Lang Stereotest was created to simplify stereopsis screening in children. It is based on two principles: random dots and cylindrical gratings. The Lang Stereotest I measures disparities: Star 600...
... test was developed to test for both crossed ... the more reliable red/green glasses to provide ... dependent on polarizing spectacles which can be quite ... attractive image of a butterfly which makes the ...
... to assist patients with red-green color deficiencies in ... off wavelengths shorter than 582 nm enabling an ... most difficult color distinctions. A color anomalous patient ... a color is in the longer or shorter ...
Medicine Products: