Rosetta Genomics to Present Multiple Posters at the 44th Annual Meeting of the American Society of Clinical Oncol...(for early detection and prognostication ...),Health

Date:5/16/2008

for early detection and prognostication"; Tuesday, June 03; 8:00AM - 12:00PM; Hall S102a; abstract # 11027. Malignant mesothelioma (MM) is an asbestos induced pleural neoplasm with a median survival (MS) of 12 months, and relatively little is known about the molecular events that lead to the development of this highly aggressive disease. Using Rosetta Genomics' unique microRNA platform, Dr. Harvey Pass, NYU School of Medicine, examines whether there are distinct mir profiles between MM and normal mesothelium, and whether mirs are associated with demographic/prognostic features in MM patients.

3. "MicroRNAs as powerful diagnostic tools for the differential diagnosis of lung tumors"; Sunday, June 01; 8:00AM - 12:00PM; Hall S A1; abstract # 11112. Lung cancer is a heterogeneous disease with many histological subtypes, further complicated by the frequent occurrence of lung metastases from various tumor origins. Therefore, determining the correct diagnosis of any lung tumor often poses a difficult diagnostic challenge that may have very significant therapeutic implications. This poster will detail the use of microRNAs for differentiating between different primary lung tumors and metastases to the lung.

4. "MicroRNA expression profile identifies origin of tumors in the liver"; Tuesday, June 03; 8:00AM - 12:00PM; Hall S102a; abstract # 11026. The distinction of liver metastasis from hepatocellular carcinoma (HCC) and determining its tissue origin is a frequent problem in oncology, especially since liver metastases, and particularly adenocarcinoma, may mimic the morphology and immunoexpression of hepatocellular carcinoma. Such distinction has significant therapeutic and prognostic implications. In the present study, Rosetta Genomics and collaborators use microRNAs as biomarkers for tissue identification to distinguish between HCC and metastatic tumors in the liver.

Publication only abstracts:

5. "MicroRNAs as specific biomarkers for distinguishin
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