The Study Demonstrates microRNAs Extracted From a Simple Blood Draw Have the Potential to Serve as Effective Clinical Biomarkers for a Wide Range of
Indications Using This Proprietary Technology, Rosetta Genomics is Currently Developing
a Blood-Based Test to Detect Colon Cancer
REHOVOT, Israel and JERSEY CITY, New Jersey, September 5 /PRNewswire-FirstCall/ -- Rosetta Genomics, Ltd. (NASDQ: ROSG), a leader in the development of microRNA-based diagnostic and therapeutic products, announced today that the results of a study conducted by its scientists describing the identification of microRNA biomarkers in blood serum, have been published online in the peer-reviewed journal PLOS One. The findings demonstrate that microRNAs have the potential to be used as clinical biomarkers for a wide range of indications in cancer and women's health.
Using its proprietary extraction and quantification methods, Rosetta Genomics is now advancing the development of a blood-based test which will utilize microRNAs to detect patients with colon cancer.
"This study further validates our understanding that microRNAs may be used as clinical biomarkers for a wide range of indications, both through invasive and non-invasive methods," noted Dr. Dalia Cohen, Chief Scientific Officer of Rosetta Genomics. "The results of this study are the basis of one of our development programs to detect colon cancer via microRNAs identified in serum. I believe our strong scientific capabilities will continue to produce exciting studies, which we will share once available."
The paper, "Serum MicroRNAs are Promising Novel Biomarkers" is now available on PLOS One website on http://dx.plos.org/10.1371/journal.pone.0003148
MicroRNAs (miRNAs) are recently discovered, naturally occurring, small RNAs that act as master regulators and have the potential to form the basis for a new class of diagnostics and therapeutics. MicroRNAs have been shown to have different expression profiles in various pathological conditions. As a result, these differences may provide for a novel diagnostic strategy for many diseases.
About Rosetta Genomics
Rosetta Genomics (Nasdaq: ROSG) is a leader in the field of microRNA. Founded in 2000, the company's integrative research platform combining bioinformatics and state-of-the-art laboratory processes has led to the discovery of hundreds of biologically validated novel human microRNAs. Building on its strong IP position and proprietary platform technologies, Rosetta Genomics is working on the application of these technologies in the development of a full range of microRNA-based diagnostic and therapeutic tools, focusing primarily on cancer and various women's health indications. The first test based on the company's technology, differentiating squamous from non squamous non small cell lung cancer, is now approved through Columbia University Medical Center's High Complexity Molecular Pathology Laboratory. In Addition, the company expects two additional microRNA diagnostic tests applying its technology will be validated and submitted for regulatory approval by licensed clinical laboratories in the United States in 2008.
Forward-Looking Statement Disclaimer
Various statements in this release concerning Rosetta's future
expectations, plans and prospects, including without limitation, statements
relating to the potential of microRNAs extracted from blood to serve as
effective biomarkers for a wide range of indications, including colon
cancer, the role of microRNAs in human physiology and disease, the
potential of microRNAs in the diagnosis and treatment of disease, and the
timing of launch of the first diagnostic tests applying Rosetta's microRNA
technology constitute forward-looking statements for the purposes of the
safe harbor provisions under The Private Securities Litigation Reform Act
of 1995. Actual results may differ materially from those indicated by these
forward-looking statements as a result of various important factors,
including risks related to: Rosetta's approach to discover and develop
novel diagnostics and therapeutic tools, which is unproven and may never
lead to marketable products or services; Rosetta's ability to fund and the
results of further pre-clinical and clinical trials; Rosetta's ability to
obtain, maintain and protect the intellectual property utilized by
Rosetta's products; Rosetta's ability to enforce its patents against
infringers and to defend its patent portfolio against challenges from third
parties; Rosetta's ability to obtain additional funding to support its
business activities; Rosetta's dependence on third parties for development,
manufacture, marketing, sales, and distribution of products; Rosetta's
ability to successfully develop its candidate tools, products and services,
all of which are in early stages of development; Rosetta's ability to
obtain regulatory clearances or approvals that may be required for its
products and services; the ability to obtain coverage and adequate payment
from health insurers for the products and services comprising Rosetta's
technology; competition from others using technology similar to Rosetta's
and others developing products for similar uses; Rosetta's dependence on
collaborators; and Rosetta's short operating history; as well as those
risks more fully discussed in the "Risk Factors" section of Rosetta's
Annual Report on Form 20-F for the year ended December 31, 2007 as filed
with the Securities and Exchange Commission. In addition, any
forward-looking statements represent Rosetta's views only as of the date of
this release and should not be relied upon as representing its views as of
any subsequent date. Rosetta does not assume any obligation to update any
forward-looking statements unless required by law.
Joshua Gordon, M.D.,
|SOURCE Rosetta Genomics Ltd|
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