Navigation Links
Romark Announces Presentation of New Data for Nitazoxanide in Chronic Hepatitis C at EASL 2008
Date:4/22/2008

enced patients were randomized to

receive 12 weeks of nitazoxanide followed by either the dual regimen

(n=12) or the triple regimen (n=12) for 36 weeks. Patients received

peginterferon alfa-2a (Pegasys(R), Hoffman LaRoche) 180 micrograms once

per week; nitazoxanide was administered as one 500 mg tablet twice

daily; and ribavirin (Copegus(R), Hoffman LaRoche) was administered as

1,000 or 1,200 mg daily according to body weight. Analysis of data was

by intention to treat.

In treatment-naive patients, combination therapy with nitazoxanide plus

SOC resulted in a SVR24 rate of 79%, compared with 50% for those

treated with SOC without nitazoxanide (P=0.023). When nitazoxanide was

combined with peginterferon alone, the observed SVR24 rate in this

group was 61%. In 24 treatment-experienced patients, the addition of

nitazoxanide to SOC for 36 weeks resulted in a 25% rate of SVR,

compared with 8% when nitazoxanide was combined with peginterferon

alone. The patients treated with nitazoxanide experienced no more side

effects than patients who received the SOC.

Interim results of this trial were presented at the 58th Annual Meeting

of the American Association for the Study of Liver Diseases (AASLD) in

Boston, MA.(1)

-- A poster presentation, titled "Evaluation of a 4-week Lead-in Phase

With Nitazoxanide Prior to Nitazoxanide+Peginterferon in Treating

Chronic Hepatitis C," demonstrated that reducing a nitazoxanide lead-in

phase from 12 to 4 weeks, followed by the addition of SOC therapy, does

not compromise virologic response rates in a patient population with

different genotypes, predominately genotype 4.

Replicon studies and an early clinical experience (unpublished)

indicated that treatment with nitazoxanide alone prior to adding

<
'/>"/>
SOURCE Romark Laboratories
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Romark Initiates Clinical Trial of Alinia(R) for Chronic Hepatitis C in the United States
2. Romark Laboratories Raises $18 Million in Institutional Financing
3. Romark Laboratories Initiates Phase II Study of Nitazoxanide in Treatment-Naive Patients With Chronic Hepatitis C Genotype 1
4. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
5. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
6. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
7. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
8. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
9. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
10. Xenomics Announces Implementation of its First Diagnostic Test for Acute Myeloid Leukemia Into Clinical Practice
11. Emisphere Technologies, Inc. Announces 2007 Second Quarter Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... 21, 2014   Memorial Hermann Health System and ... today announced a new partnership to provide a new level ... care centers in the greater Houston ... become the exclusive provider of professional breast radiology services for ... Memorial City, The Woodlands , Northeast, Southwest ...
(Date:8/21/2014)... Aug. 21, 2014  Publicis Groupe customer engagement ... Managing Partner and Healthcare Industry Group Leader, has been ... recognizes the most inspiring people in the life-sciences industry. ... research and development, marketing, technology, creativity, strategy and medicine. ... as a partner in its leading Rosetta Consulting practice. ...
(Date:8/21/2014)... HAMBURG, Germany , Aug. 21, 2014  IBM (NYSE: ... Deutsches Elektronen-Synchrotron ( DESY ), a leading national research ... up management and storage of massive volumes of x-ray ... architecture based on IBM software defined technology can handle ... peak performance and help scientists worldwide gain faster insights ...
Breaking Medicine Technology:Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 2Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 3Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 4Shannon Hartley Shines in PharmaVOICE 100 2DESY and IBM Develop Big Data Architecture for Science 2DESY and IBM Develop Big Data Architecture for Science 3
(Date:8/21/2014)... (PRWEB) August 21, 2014 A new ... a 63% increase in disability associated with speech problems ... a more than 15% increase in disability associated with ... intervention for rising numbers of children who are experiencing ... (ASHA). , On a broader level, the ...
(Date:8/21/2014)... is to focus on her body in terms of ... her as a complete human being with thoughts and ... in the media, how does it affect individual romantic ... Quarterly , a SAGE journal, finds that more objectification ... incidents of sexual pressure and coercion., Researchers Laura R. ...
(Date:8/21/2014)... FRANCISCO Aug. 21, 2014 Researchers in the ... congenital cataracts can quickly and accurately diagnose a number ... a study published online today in ... Ophthalmology. Using a single test, doctors were able ... on their mutations reducing the time and money spent ...
(Date:8/21/2014)... 2014 Xarelto lawsuit ( http://www.xareltolawsuitcenter.com/ ) ... suffer uncontrollable internal bleeding and other serious injuries continue ... According to court documents, a wrongful death lawsuit was ... District of New York by the family of a ... that was allegedly caused by Xarelto. Among other thing, ...
(Date:8/21/2014)... 21, 2014 The report "Industrial ... Pollutant Control System (FGD, DeNOx, Particulate Control, Mercury ... Steel, Chemical & Others) - Global Trends & ... industrial flue gas treatment systems & services market ... size in terms of value. The industrial flue ...
Breaking Medicine News(10 mins):Health News:New Pediatrics Study Reveals Dramatic Increase in Speech Problems in Children Over Past Decade 2Health News:New Pediatrics Study Reveals Dramatic Increase in Speech Problems in Children Over Past Decade 3Health News:Objectification in romantic relationships related to sexual pressure and coercion 2Health News:New DNA test for diagnosing diseases linked to childhood blindness 2Health News:Xarelto Lawsuits Mount With New Filing in New York Federal Court, Bernstein Liebhard LLP Reports 2Health News:Xarelto Lawsuits Mount With New Filing in New York Federal Court, Bernstein Liebhard LLP Reports 3Health News:Xarelto Lawsuits Mount With New Filing in New York Federal Court, Bernstein Liebhard LLP Reports 4Health News:Industrial Flue Gas Treatment Systems Market Estimated to Worth $59, 546.7 Million by 2019 – Report by MarketsandMarkets 2Health News:Industrial Flue Gas Treatment Systems Market Estimated to Worth $59, 546.7 Million by 2019 – Report by MarketsandMarkets 3Health News:Industrial Flue Gas Treatment Systems Market Estimated to Worth $59, 546.7 Million by 2019 – Report by MarketsandMarkets 4
... WASHINGTON, July 22 The role of personal responsibility in ... Rethinking Responsibility: Reflections on Sex and Accountability. Released ... nonprofit, nonpartisan organization, the volume includes 29 essays written by leaders ... , Leading media voices, ...
... July 22 To help employers face the challenges of ... difficult economy, Sodexo, Inc., now offers a Quality of Life ... today the launch of the program designed to ... , , Sodexo, a ...
... , DALLAS, July 22 Texas ... Heart Association for providing quality, evidence-based care for coronary artery ... "This is another example of the dedication and commitment ... Dallas community by physicians, nursing, allied health professionals and administration," ...
... , WALNUT CREEK, Calif., July 22 ... cure with the recent approval by The National Institutes of Health ... scientists, parents and advocates. , , ... to highlight the work of the NIH,s Research Plan on Fragile ...
... demands of surgical careers, most surgeons would still choose their ... postpone having children or to not have children at all ... national survey conducted by UC Davis researchers has found. The ... Surgery , one of the JAMA/Archives journals. "Surgery is ...
... associated with varied, disproportionate, asymmetric overgrowth of many ... seen in Proteus syndrome is progressive and difficult ... treatment for the progressive overgrowth of tissue over ... functional and cosmetic consequences, so surgical intervention is ...
Cached Medicine News:Health News:National Leaders Examine Sex and Responsibility in New Book 2Health News:National Leaders Examine Sex and Responsibility in New Book 3Health News:Sodexo Offers Landmark Program to Promote Employee Health and Worklife Balance 2Health News:Texas Health Dallas Receives Double Honor From American Heart Association 2Health News:NIH Plan Charts Course to Better Treatments and Cure for Most Common Known Genetic Cause of Autism: Fragile X 2Health News:UC Davis study highlights work-life issues of female surgeons 2
... Tech acclaimed GT-CAPTURE digital camera photomicrographic system ... microscope such as Olympus, Leica, Nikon, and ... and transferring images over the Internet easy ... and a performance-proven Nikkor lens. The system ...
... superb stand-alone digital camera with networking capability ... or remote locations. Image acquisition and camera ... operates independently or attaches directly to a ... to capture and transfer images. Sharing images ...
... are a new generation of flexible CCD cameras, ... video imaging. Images are captured by a high-resolution ... and digital formats. Video signals include composite video, ... to the PC as uncompressed TIFF files. And ...
Console Horizontal Airflow Cabinet...
Medicine Products: