Navigation Links
Romark Announces Presentation of New Data for Nitazoxanide in Chronic Hepatitis C at EASL 2008
Date:4/22/2008

enced patients were randomized to

receive 12 weeks of nitazoxanide followed by either the dual regimen

(n=12) or the triple regimen (n=12) for 36 weeks. Patients received

peginterferon alfa-2a (Pegasys(R), Hoffman LaRoche) 180 micrograms once

per week; nitazoxanide was administered as one 500 mg tablet twice

daily; and ribavirin (Copegus(R), Hoffman LaRoche) was administered as

1,000 or 1,200 mg daily according to body weight. Analysis of data was

by intention to treat.

In treatment-naive patients, combination therapy with nitazoxanide plus

SOC resulted in a SVR24 rate of 79%, compared with 50% for those

treated with SOC without nitazoxanide (P=0.023). When nitazoxanide was

combined with peginterferon alone, the observed SVR24 rate in this

group was 61%. In 24 treatment-experienced patients, the addition of

nitazoxanide to SOC for 36 weeks resulted in a 25% rate of SVR,

compared with 8% when nitazoxanide was combined with peginterferon

alone. The patients treated with nitazoxanide experienced no more side

effects than patients who received the SOC.

Interim results of this trial were presented at the 58th Annual Meeting

of the American Association for the Study of Liver Diseases (AASLD) in

Boston, MA.(1)

-- A poster presentation, titled "Evaluation of a 4-week Lead-in Phase

With Nitazoxanide Prior to Nitazoxanide+Peginterferon in Treating

Chronic Hepatitis C," demonstrated that reducing a nitazoxanide lead-in

phase from 12 to 4 weeks, followed by the addition of SOC therapy, does

not compromise virologic response rates in a patient population with

different genotypes, predominately genotype 4.

Replicon studies and an early clinical experience (unpublished)

indicated that treatment with nitazoxanide alone prior to adding

<
'/>"/>
SOURCE Romark Laboratories
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Romark Initiates Clinical Trial of Alinia(R) for Chronic Hepatitis C in the United States
2. Romark Laboratories Raises $18 Million in Institutional Financing
3. Romark Laboratories Initiates Phase II Study of Nitazoxanide in Treatment-Naive Patients With Chronic Hepatitis C Genotype 1
4. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
5. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
6. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
7. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
8. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
9. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
10. Xenomics Announces Implementation of its First Diagnostic Test for Acute Myeloid Leukemia Into Clinical Practice
11. Emisphere Technologies, Inc. Announces 2007 Second Quarter Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... Sept. 30, 2014 The signing of ... and New Jersey Health Foundation (NJHF) to work ... care programs has been announced by Rodger ... Kessler Foundation and James M. Golubieski , ... "The experience of New Jersey Health Foundation in ...
(Date:9/30/2014)... ATLANTA , Sept. 30, 2014  Georgia-Pacific ... systems, towels and tissue for a wide range ... success of its product lines in healthcare, including ... practices, Georgia-Pacific Professional is introducing its healthcare products ... "Georgia-Pacific Professional understands the importance of infection control ...
(Date:9/30/2014)... 2014 In a recent study ... backflow of the Eldor spinal needle 25G, 103 mm ... pencil point spinal needles of the same gauge and ... anesthesia is an excellent type of regional anesthesia for ... etc. It is estimated that 100 million ...
Breaking Medicine Technology:Kessler Foundation Partners with New Jersey Health Foundation To Start Innovative Companies To Change the Lives of People with Disabilities 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 3
(Date:9/30/2014)... 30, 2014 A group of Americans is ... an epidemic that, left unchecked, could create a catastrophic, global ... headed to Africa. John Rogers, the Executive Director the Eugene ... to fight a disease most think mankind conquered long ago: ... years ago is on the comeback in several countries - ...
(Date:9/30/2014)... 2014 Two revolutionary procedures now being utilized ... gum disease a far less painful and far more ... you’ve ever felt electric shock waves surge through your teeth ... beverage, it’s possible you already know the impact of receding ... general dentist in West Palm Beach, and a Fellow in ...
(Date:9/30/2014)... (HealthDay News) -- Medicare should cover low-dose computed tomography ... the disease, a coalition of more than 60 patient ... the Lung Cancer Alliance, the Society of Thoracic Surgeons, ... and the American Society of Clinical Oncology, made its ... Centers for Medicare & Medicaid Services (CMS). Such ...
(Date:9/30/2014)... Defense has made progress in reducing the stigma associated ... and post-traumatic stress disorder, but more improvement is still ... Despite efforts of both the Defense Department and the ... service members still do not seek needed care for ... concerted effort to promote treatment as a way to ...
(Date:9/30/2014)... that causes a rare premature aging disease could lead ... unstoppable cell division that makes cancer so deadly. ... U-M Health System recently discovered a protein mutation that ... hematopoietic stem cells can,t regenerate and make new blood. ... cancer and bone marrow failure. , But the ...
Breaking Medicine News(10 mins):Health News:US Delegation Heads to North Korea to Combat Tuberculosis Epidemic 2Health News:Florida Dentist Battles Gum Disease With Latest Techniques 2Health News:Florida Dentist Battles Gum Disease With Latest Techniques 3Health News:Groups Call for Medicare Coverage of Lung Cancer Screening 2Health News:US military making progress reducing stigma tied to seeking help for mental illness 2Health News:US military making progress reducing stigma tied to seeking help for mental illness 3Health News:Disease decoded: Gene mutation may lead to development of new cancer drugs 2
... Nutrition Month(R), and Cabot Creamery Cooperative(R) offers, ... they age, CABOT, Vt., Feb. 19 March ... Dietetic Association,s campaign to promote,the importance of eating a ... to eat better, smarter and,healthier. Research by the US ...
... Harvard-Trained Cosmetic and Laser,Surgeon and Board Certified ... Relations to spearhead her PR campaign. Dr. Jacob,Director ... performs a variety of medical procedures and services, ... A veteran in the field, Dr. Jacob works ...
... Hyperactivity Disorder in ... Throughout Asia -, NEW HAVEN, Conn. and KORTRIJK, ... specialty pharmaceuticals company,focused on bringing proprietary medicines to the ... announced that RHEI has,licensed from MethaPharma the exclusive right ...
... Feb. 18 The following was,released today by ... Ambulance diversion? Crowded,emergency departments? Reports and articles over ... longer emergency department wait times (in,excess of 12 ... than one,third of area hospitals were to divert ...
... An international team of scientists led by a University ... into the realm of consciousness. , The scientists have ... perception, by showing how single neurons in the human ... of Leicester bioengineer Dr Rodrigo Quian Quiroga is spearheading ...
... atrial fibrillation, analysis shows , , MONDAY, Feb. 18 (HealthDay ... that are prescribed to lower cholesterol levels may also ... that boosts the odds of a stroke, French researchers ... more than 3,500 participants showed that those patients who ...
Cached Medicine News:Health News:Hey Boomers, Here's to Your Health! 2Health News:Hey Boomers, Here's to Your Health! 3Health News:Hey Boomers, Here's to Your Health! 4Health News:Hey Boomers, Here's to Your Health! 5Health News:Dr. Carolyn Jacob Hires Empower Public Relations 2Health News:RHEI Pharmaceuticals Licenses Attental From MethaPharma (Vemedia Group) for Distribution Throughout Asia 2Health News:RHEI Pharmaceuticals Licenses Attental From MethaPharma (Vemedia Group) for Distribution Throughout Asia 3Health News:Gilbert Hospital Turns the Tables on the Flu 2Health News:Scientists explore consciousness 2Health News:Scientists explore consciousness 3Health News:Cholesterol-Lowering Drugs May Ease Irregular Heartbeat 2Health News:Cholesterol-Lowering Drugs May Ease Irregular Heartbeat 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: