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Romark Announces Data Presented at AASLD Meeting 2010
Date:11/1/2010

TAMPA, Fla., Nov. 1, 2010 /PRNewswire/ -- Romark Laboratories announced that data from studies of nitazoxanide in hepatitis C are being presented at the 61st Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), also known as The Liver Meeting® in Boston, October 30 – November 2, 2010.

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"The data presented at AASLD provide important support for our ongoing clinical development program for nitazoxanide in chronic hepatitis C (CHC)," said Jean-Francois Rossignol, M.D., Ph.D., Chairman and Chief Science Officer of Romark.  "Extensive studies have shown that nitazoxanide does not induce mutations that confer viral resistance – one of the most challenging problems associated with antiviral therapy.  Other studies highlight the important role of nitazoxanide in stimulating the interferon signaling pathway and a potential role for nitazoxanide in special populations such as relapsers and liver transplant patients."  

Another major finding reported at AASLD is the activity of nitazoxanide-related compounds (called thiazolides) against HCV.  Collectively, these studies provide further rationale for the use of nitazoxanide and other thiazolides as part of a new approach to chronic hepatitis C therapy – an approach that focuses on reducing the number of drugs and the toxicities associated with treatment.

Investigators from Georgetown University, the National Institutes of Health, and Mayo Clinic have presented or will present their data on October 31 and November 2.  The three presentations are listed and described briefly below:

1. HCV Resistance to Nitazoxanide is not due to Changes in the Viral Sequence.  Brent Korba, Microbiology & Immunology, Georgetown Univ. Med. Ctr., Washington, DC. Poster session: T
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SOURCE Romark Laboratories, L.C.
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