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Romark Announces Clinical Trial Results for New Influenza Drug Presented at IDSA Meeting 2011
Date:10/21/2011

atment group).  86 adults and adolescents were enrolled in the second trial (43 per treatment group).  Respiratory viruses were detected by ELISA at baseline in only approximately 15% of the patients.  In each of the two trials, treatment with NTZ was associated with a statistically significant reduction in duration of symptoms compared to the placebo.  In the pediatric study, median time from first dose to alleviation of symptoms was 4 days for the NTZ treatment group compared to >7 days for the placebo treatment group (P<0.0001).  In the study involving adults and adolescents, median time from first dose to alleviation of symptoms was 4 days compared to 7 days for the placebo treatment group (P=0.037).  In the pediatric study, 60% of the patients in the placebo treatment group required post-study antibiotics compared to only 8% in the NTZ treatment group (P<0.0001).  In the adult/adolescent study, 36% of the patients in the placebo treatment group required post-study antibiotics compared to 18% in the NTZ treatment group (P=0.13).  In each study, adverse events were similar between the treatment groups.

About Influenza

Influenza is a highly contagious acute respiratory illness caused by influenza viruses including the new H1N1 influenza. Common symptoms include fever, runny nose, nasal congestion, sneezing, cough, sore throat, headache, muscle aches, sweats, chills and fatigue. Influenza illness affects all age groups and can lead to complications including sinusitis, otitis, bronchitis, pneumonia and central nervous system disease. In the United States, influenza is responsible for approximately 36,000 deaths and 216,000 hospitalizations per year.

About Romark Laboratories

Romark Laboratories, L.C. (www.romark.com) is a biopharmaceutical company committed to the discovery and development of innovative new small
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SOURCE Romark Laboratories, L.C.
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