Navigation Links
Romark Announces Clinical Trial Results for New Influenza Drug Presented at IDSA Meeting 2011
Date:10/21/2011

iate another Phase 3 clinical trial of NT-300 during the coming flu season and to seek FDA approval to market NT-300 for treatment of acute uncomplicated influenza.  The company also plans to develop NT-300 for prevention of influenza and for treatment of influenza in special populations (e.g., pediatric patients under 12 years of age, geriatric patients and patients with severe illness or underlying medical conditions).

NT-300, an investigational new drug in the United States, is an oral controlled release tablet that contains 300 mg of nitazoxanide (NTZ) as active ingredient. NTZ is the first of a new class of small molecule immunomodulatory drugs called thiazolides. Romark is using this new class of drugs as a technology platform for developing new drugs for treating a broad range of viral diseases and cancers.  NT-300 is undergoing clinical development for treatment of influenza.

There are presently only two classes of drugs approved by the FDA for treating flu: the neuraminidase inhibitors, oral Tamiflu® (oseltamivir) and inhaled Relenza® (zanamivir), and the older M2 inhibitors, amantadine and rimantadine. The M2 inhibitors are no longer effective against circulating influenza strains. Resistance to the neuraminidase inhibitors has been observed, and during the 2008-2009 flu season, approximately 99% of circulating influenza A H1N1 strains were resistant to oseltamivir (Tamiflu®), the only oral drug for treating influenza. There has not been a new class of drugs approved for treating influenza since Tamiflu® and Relenza® were approved by FDA in 1999.  

Data from laboratory studies of NTZ to be presented at the IDSA meeting have shown that NTZ is active against a broad range of influenza viruses including oseltamivir- and amantadine-resistant strains.  Laboratory studies designed to create or select for influenza strains resistant to NTZ could not identify viruses resistance to NTZ in cell cult
'/>"/>

SOURCE Romark Laboratories, L.C.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Romark Initiates Clinical Trial of Alinia(R) for Chronic Hepatitis C in the United States
2. Romark Laboratories Raises $18 Million in Institutional Financing
3. Romark Laboratories Initiates Phase II Study of Nitazoxanide in Treatment-Naive Patients With Chronic Hepatitis C Genotype 1
4. Romark Announces Presentation of New Data for Nitazoxanide in Chronic Hepatitis C at EASL 2008
5. Romark Laboratories Completes Enrollment in U.S. Phase II Study of Nitazoxanide for Chronic Hepatitis C Genotype 1 Non-Responders
6. Romark Initiates Clinical Trial of Alinia for Treatment of Influenza
7. NeuroFocus and New Scientist Magazine Apply Neuromarketing to Select Cover Design
8. Intercell and Romark Join Forces in Combining Therapies Against Hepatitis C
9. Romark and Intercell Join Forces in Combining Therapies Against Hepatitis C
10. Romark Announces Data Presented at AASLD Meeting 2010
11. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... KENNEWICK, Wash. , Dec. 19, 2014 /PRNewswire/ ... late stage development company engaged primarily in the ... diagnostic and therapeutic applications, today announced that a ... Grant has been awarded for which AMIC is ... Washington State University (WSU) for the proposal titled ...
(Date:12/19/2014)... 19, 2014  Monarch America Inc. (OTCQB: CANK) ("Monarch ... pleased to provide this review of the Company,s recent ... "Over this past year, we achieved many ... extremely proud to say that Monarch America is in ... has ever been," stated Eric Hagen , CEO ...
(Date:12/19/2014)... LOS ALTOS, Calif. , Dec. 18, 2014 ... of a new generation of equipment for the ... today the release of the new Luminary™ Profiler, ... highly accurate light-based measurement in a cost-effective, portable ... to meet the specific needs of the cannabis ...
Breaking Medicine Technology:Advanced Medical Isotope Corporation Awarded LSDF Grant As Commercialization Partner 2Advanced Medical Isotope Corporation Awarded LSDF Grant As Commercialization Partner 3Monarch America Inc. CEO Reviews Recent Achievements and Provides Outlook for 2015 2Monarch America Inc. CEO Reviews Recent Achievements and Provides Outlook for 2015 3Sage Analytics Develops Breakthrough System for Potency Testing of Cannabis Products 2
... , MORGANTOWN, W.Va. , Feb. 12 ... of surgical technologies, medical devices and telehealth programs. , ... programs can support nursing care providers in a variety ... by adding an extra layer of providers (remotely). ...
... WASHINGTON , Feb. 12 Members of ... a quick recovery following his recent hospitalization for angioplasty ... communicated a desire to return to work promptly. Because angioplasty ... chest, most patients who receive coronary stents leave the hospital ...
Cached Medicine Technology:SCAI Statement on the Hospitalization of Former President Bill Clinton 2
(Date:12/20/2014)... 20, 2014 Recently, AngelWeddingDress.com has introduced ... ”) for the coming Christmas. In the promotion, all ... off. , “We have something special for the women ... holiday season. Moreover, our new collections of 2015 dresses ... offered now at greatly discounted prices. Visit our website ...
(Date:12/20/2014)... Today, Balfleet.com, one of the most outstanding ... 50%-70% off on its Mother of the Bride ... of the bride dresses from Balfleet.com feature gorgeous looks ... and takes pride in providing high quality dresses to ... great discounts on our mother of the bride dresses, ...
(Date:12/19/2014)... Energy Textiles is excited to ... Celliant, the world’s leading responsive textile, can now ... There are a number of benefits to wearing ... and balanced body temperature; which can lead to ... enhanced athletic performance; and overall wellness. In addition, ...
(Date:12/19/2014)... These vanadium reserves are mostly found ... 151,000 tons of vanadium were produced globally in 2013, ... increased at 6.7% AAGR during the period from 2001 ... being the largest consumer, accounted for more than 90% ... alloy and the chemical industry. , View Full Report ...
(Date:12/19/2014)... 19, 2014 (HealthDay News) -- The intestinal bacteria that ... ulcerative colitis, may be inherited, researchers report. The ... , could help in efforts to prevent the disease ... colitis, the study authors added. "The intestinal bacteria, ... age can have a big impact on your health ...
Breaking Medicine News(10 mins):Health News:AngelWeddingDress Has Introduced Its Special Offer For The Coming Christmas 2Health News:Balfleet.com is Offering 50%-70% Off of its Mother of the Bride Dresses 2Health News:Energy Textiles Launches Celliant Revitalizing Bedsheets 2Health News:Marketresearchreports.biz: Global Vanadium Usage Increased at AAGR of 6.7% between 2001 and 2013 2Health News:Marketresearchreports.biz: Global Vanadium Usage Increased at AAGR of 6.7% between 2001 and 2013 3Health News:Crohn's, Colitis May Have Genetic Underpinnings, Study Finds 2
... new cases of bird flu in the impoverished Southeast Asian ... victory over bird flu with no new outbreaks of the ... official media report that has been. Yangon notified the world ... the H5N1 virus, which first emerged in central Myanmar in ...
... JAMA, The Journal of the American Medical Association finds ... hard as ever. Doctors' training, or// residency includes shifts ... Accreditation Council for Graduate Medical Education (ACGME) say that ... MD, MPH, of Harvard Medical School, and colleagues said ...
... in Delhi Wednesday said they were fully prepared to deal ... ignorance about three cases being detected// in the city. ... detected in Delhi. Since the disease is quite similar to ... with the viral infection," said N.K. Yadav, additional municipal health ...
... leader in oral care, in association with the Indian ... observed as Oral Health Month. Now in its third ... oral health awareness campaign in India to establish and ... all ages. This year, the theme of Oral Health ...
... could be dying due to respiratory diseases including asthma.// ... conducted this study, according to which, some deaths and ... are not reported. ,Shortness of breath, wheezing, ... asthma, a chronic respiratory condition. COPD is too a ...
... of the Scottish Executive Health experts, NHS forth valley has ... programme, which will necessitate and all babies under the age ... against a lethal meningitis form. The number of doses ... children. ,Nearly 700 cases of meningitis and septicemia ...
Cached Medicine News:Health News:Myanmar Declares Herself As A Country Free of Bird flu 2Health News:Delhi Gears up to Fight Chikungunya Fever 2Health News:Striving to Make India Free from Tooth Decay 2Health News:Asthma –an underlying or associated cause of death 2
Sterile squares of smooth foil for repair of the floor of the orbit and other plastic surgery. Available in large size....
The rectangular large-field lens of the 2631 are ideal for reading and writing....
Thinprofile design eyelid implants....
Bausch & Lomb magnifiers incorporates precision optics and patented ergonomic designs for increased clarity and comfort during use....
Medicine Products: