Navigation Links
Roche's Investigational Polymerase Inhibitor, Combined with PEGASYS(R) and COPEGUS(TM), Shows Potent Antiviral Activity in Treatment of Chronic Hepatitis C at Four Weeks
Date:11/2/2007

University of Florida, Gainesville, and a lead investigator in this Phase IIb study.

About Hepatitis C

Hepatitis C is a blood-borne infectious disease of the liver and a leading cause of cirrhosis, liver cancer and the need for liver transplants. According to the Centers for Disease Control and Prevention (CDC), an estimated 4.1 million Americans (1.6 percent) have been infected with hepatitis C; 3.2 million are chronically infected. The number of new infections per year has declined from an average of 240,000 in the 1980s to about 26,000 in 2004. CDC estimates the number of hepatitis C-related deaths could increase to 38,000 annually by the year 2010, surpassing annual HIV/AIDS deaths.

About PEGASYS

PEGASYS, in combination with COPEGUS (ribavirin), are indicated for the treatment of adults with chronic hepatitis C who have compensated liver disease and have not previously been treated with interferon alpha. Efficacy has been demonstrated in patients with compensated liver disease and histological evidence of cirrhosis (Child-Pugh class A) and patients with HIV disease that are clinically stable (e.g., antiretroviral therapy not required or receiving stable antiretroviral therapy). In addition, PEGASYS in combination with COPEGUS is the first and only FDA-approved regimen for the treatment of chronic hepatitis C in patients coinfected with hepatitis C and HIV. PEGASYS is the only pegylated interferon indicated for the treatment of adult patients with chronic hepatitis B (HBeAg positive and HBeAg negative chronic hepatitis B who have compensated liver disease and evidence of viral replication and liver inflammation).

PEGASYS is dosed at 180mcg as a subcutaneous injection taken once a week. COPEGUS is available as a 200mg tablet, and is administered orally two times a day as a split dose. Roche has backed PEGASYS with the most extensive clinical research program ever undertaken in hepatitis C, with major studies initiated to advance treat
'/>"/>

SOURCE Roche
Copyright©2007 PR Newswire.
All rights reserved

2

GOOD

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
2. An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes
3. Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes
4. Investigational Study Demonstrated a Re-Establishment of Clinical Improvement with Orencia (Abatacept) in Children with Juvenile Idiopathic Arthritis upon Re-Introduction of Therapy
5. Mercks Investigational Migraine Treatment MK-0974 Significantly Improved Migraine Pain on Several Efficacy Measures in a Phase II Study
6. Data Demonstrated Metastatic Melanoma Response to Investigational Immunotherapy Ipilimumab
7. Investigational Drug Cediranib (AZD2171) Shows Promise in Patients With Recurrent Glioblastoma (GBM)
8. Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting
9. Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting
10. Investigational Cancer Drug Pertuzumab Shows Promising Results in Advanced Breast Cancer When Combined with Herceptin
11. Shire Announces Positive Results of Studies With Guanfacine Extended Release, An Investigational Nonstimulant Medication Filed for the Treatment of ADHD in Children and Adolescents

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2009)...wire-FirstCall/--ThoratecCorporation(Nasdaq: THOR ...upporttherapiestosave,supportandrestorefailinghear...alPiperJaffrayHealthCareConferenceonTuesday,Decemb...hieffinancialofficer,willprovideanupdateonthecompa....,PacificStandardTime). ,, Thepresentationwillb...
(Date:11/24/2009)...--PharmaceuticalInstitute,aleadingproviderofspecia...chindustry,todayannouncedthelaunchofanewe-courseti...ace e-courseisthenewestadditiontothecompany,s Mana...esofe-coursesdesignedtofillthecriticalneedforbasic...fessionals. ,, Thenewthreemodule HospitalMarket...
(Date:11/24/2009)...bitBiosciencesCorporationannouncedtodaythattherewi...ondgenerationFLT3inhibitor,inAMLatthe51stAmericanS...rleans,LA,December5-8,2009.Anoralpresentationwillh...apysafetystudyinadultswithacutemyeloidleukemia(AML...uatingtheeffectofAC220monotherapyandincombinationw...
Breaking Medicine Technology:Pharmaceutical Institute Launches New Training Resource Focused on the Hospital Marketplace 2Ambit Biosciences Corporation Announces Presentations Profiling AC220 Clinical and Non-Clinical Data at 51st American Society of Hematology Annual Meeting 2Ambit Biosciences Corporation Announces Presentations Profiling AC220 Clinical and Non-Clinical Data at 51st American Society of Hematology Annual Meeting 3Ser Padres Joins Forces with la Doctora Alizas VidaySalud com to Offer the Hispanic Community Unprecedented Online Health Related Content in Spanish 49632 1Ser Padres Joins Forces with la Doctora Alizas VidaySalud com to Offer the Hispanic Community Unprecedented Online Health Related Content in Spanish 49632 2Ser Padres Joins Forces with la Doctora Alizas VidaySalud com to Offer the Hispanic Community Unprecedented Online Health Related Content in Spanish 49632 3DIA Annual Meeting Attendees Invited to Participate in Electronic Data Capture 28EDC 29 Clinical Trial Survey 4626 1DIA Annual Meeting Attendees Invited to Participate in Electronic Data Capture 28EDC 29 Clinical Trial Survey 4626 2Unspoken memories of Holocaust survivors find silent and nonpathological expression 49625 1Unspoken memories of Holocaust survivors find silent and nonpathological expression 49625 2
...ax Will Remain the NSTEMI Market Share Leader Thro...Resources , , WALTHAM, Mass., Feb. 25 Decision R...advisory firms for pharmaceutical and healthcare i...of mortality at 30 days is the attribute that most...cisions in non-ST elevation myocardial infarction ...
...res and infections of the bone are among most seri...Severe musculoskeletal conditions in children incl... as slipped epiphysis, and elbow fractures. These ...mplications if children are not treated properly a...leased today at the 2009 Annual Meeting of the Am...
Other Medicine Technology:Angiomax Will Retain Decision Resources' Proprietary Clinical Gold Standard Status Over Current and New Therapies, Including Recently-Approved Efient, for the Treatment of NSTEMI 2Angiomax Will Retain Decision Resources' Proprietary Clinical Gold Standard Status Over Current and New Therapies, Including Recently-Approved Efient, for the Treatment of NSTEMI 3Children and Orthopaedic Surgical Emergencies 2Children and Orthopaedic Surgical Emergencies 3
(Date:11/25/2009)... Beginning Today through Sunday, Novembe...ery memory foam and latex sofa bed mattress + an a...ng and a 100 night money back guarantee. Use the c... to take advantage of this special offer. , ...llions of Americans will travel from Thanksgiving ...
(Date:11/25/2009)... The American Society of Hematology (ASH...ishing, education, and media company, are launchin...namic science curriculum designed to spark interes...on to exposing students to exciting career opportu...ashington (PRWEB) November 25, 2009 -- The America...
(Date:11/25/2009)...November25/PRNewswire/--Therearemanywaysyoucanimpr...sults.Butthere,alwaysseemstobeconflictingadvicecon...rhealth. , So,therealbuzz.comteamhascompileda...tymuchincontrovertible!Doingacombinationof,oursugg...festyle,andwell-being-sotrythemout. , 1.Reduc...
(Date:11/24/2009)... amounts of salt is linked to a significantly high...tes a paper published today in the British Medica...ly by the World Health Organization,s Collaboratin... Warwick and University Hospital in Coventry, UK, ...e Centre in Hypertension based at the Department o...
(Date:11/24/2009)...ELDHILLS,Mich.,Nov.24/PRNewswire/--SkyFoundation,I...0tofundresearchtodevelopabloodtestfortheearlydetec...rethat$100,000sinceitsinceptioninJune2008.Theannou...dation,aftertheorganization,sfirstmajorfundraiser....ovember8,atabrunchatTheVillageClubinBloomfieldHill...
Breaking Medicine News(10 mins):Health News:Providing Comfort for Holiday Guests Just Got Easier 2Health News:Providing Comfort for Holiday Guests Just Got Easier 3Health News:New Science Program Teaches High School Students About Blood and Career Opportunities in the Field of Hematology 2Health News:New Science Program Teaches High School Students About Blood and Career Opportunities in the Field of Hematology 3Health News:realbuzz.com - Top 25 Ways to Improve Your Health & get a Better Sex Life! 2Health News:High salt intake linked to strokes and cardiovascular disease 2Health News:Sky Foundation, Inc. Raises More Than $100,000 to Find a Test for Early Detection of Pancreatic Cancer 2
...published in the latest issue of BMJ said that mul...prevent infections in the elderly population. ...neral deficiency, which can lead to poor immunity ...fluence on infections. Researchers at Aberdee...
...he choice by many for latest and quick medical tre...year-old son, Elliot Knott to India for treatment ... an operation in the NHS. The decision to s...ft housebound from an ice-skating injury, then fac...
...ration FDA has recently announced that it has plan...rug advertisements. The FDA and the pharmaceu...ising practices for drugs, with agency research sh...tical industry advertising led to revised guidelin...
...m will Friday inaugurate the world's first state-o...ormatics here. Jointly established and managed...ics (CDFD) and Sun Microsystems Inc, the centre wi...ng a network of computers in a grid system. W...
... programmes that involve high doses of vitamins an... unwitting 'guinea pigs', according to British res...m effects there might be from taking supplements a...ssionals who turned to vitamins and minerals in se...
...issue of Harvard Women’s Health Watch had explored...me women in their menopausal or postmenopausal age...al women—and to many who are in peri-menopause, th...a feeling of being on fire. Although the phy...
Other Medicine News:Health News:Indian Hospitals – A Destination For Quality Medical Care 2Health News:New Bioinformatics Centre to open in Andhra 2Health News:Vitamin Supplements - Good, The Bad And The Ugly 2Health News:Vitamin Supplements - Good, The Bad And The Ugly 3Health News:Insight for Hot Flashes In Postmenopausal Women 2
AP250 Auto Chart Projector
ResMed VPAP III ST
...entilator is a blower-based, bi-level positive pre...ously breathing patients weighing 30 kg or more. T... insufficiency and/or obstructive sleep apnea in t...The KnightStar 330 Ventilator includes a 3-30 cm H...
GoodKnight® 425 Bi-Level® Device
Medicine Products: