Navigation Links
Roche responds to announcement of 'IDEAL' hepatitis C trial results
Date:1/14/2008

nical data and patient and physician preference. We are convinced that physicians and patients will continue to choose PEGASYS/ribavirin combination therapy based on positive experience and sound clinical evidence," said George Abercrombie, President and CEO, Hoffmann-La Roche. "Our current focus at Roche is on advancing the treatment of hepatitis C by optimizing doses and duration of PEGASYS/ribavirin in patients with unmet medical need, while developing new compounds that have the potential to offer a successful outcome to even more patients."

Roche believes that it is critical for patients and physicians to receive complete information to fully understand the results of "IDEAL," so that treatment decisions can be based on sound scientific data.

Please see below for additional information about the "IDEAL" trial, Roche and PEGASYS, including important safety information.

"IDEAL" Trial Design Issues

* Starting doses of ribavirin were different in the Peg-Intron and

PEGASYS arms of the study

* The design calls for a more drastic ribavirin dose reduction for side

effect management in most patients in the PEGASYS arm compared to

patients in the Peg-Intron arms; in some cases, ribavirin dose

reductions for patients in the PEGASYS arm were three times greater

than for patients in the Peg-Intron arms. This is important because a

substantial number of patients being treated for hepatitis C require

their ribavirin dose to be reduced to manage side effects, and this

could have an impact on the efficacy of the regimen

* The PEGASYS arm was not blinded, meaning that patients and physicians

knew which treatment was being administered. Many comparative studies

are blinded to ensure that bias does not compromise the results

* Erythropoetin (EPO) is a medication that is often given to treat

ribavirin-related anemia and help pat
'/>"/>

SOURCE Roche
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Roche Submits Application for FDA Approval of ACTEMRA(R) for the Treatment of Rheumatoid Arthritis
2. Two Pivotal Phase III Studies for Roches ACTEMRA(TM) (tocilizumab) Demonstrate Significant Improvement in Rheumatoid Arthritis Symptoms
3. Roches Investigational Polymerase Inhibitor, Combined with PEGASYS(R) and COPEGUS(TM), Shows Potent Antiviral Activity in Treatment of Chronic Hepatitis C at Four Weeks
4. Roche Diagnostics HIV Viral Load Test Used in Clinical Trials for Isentress, a New Class of HIV Drug
5. Roche Announces Positive Results in Solid Tumors Using Human Monoclonal Antibody Against IGF-1R (R1507)
6. MacroChem Acquires Rights to Pexiganan, a Novel Topical Anti-Infective for Treatment of Diabetic Foot Infections, From Genaera
7. Rochester Medical Anti-Infection Foley Catheter Demonstrates Effectiveness in Randomized Trial
8. Researchers Identify Virus Possibly Responsible for Declining Honeybee Population Using 454 Sequencing Technology from Roche
9. Wyeths Torisel and Roche/Genentechs Avastin Will Challenge Pfizers Sutent to Become the Clinical Gold Standard for Treatment of Metastatic Renal Cell Carcinoma
10. Solvay Pharmaceuticals, Inc. Responds to Advisory Committee Recommendation for Further Study of Tedisamil to Treat Atrial Fibrillation
11. Schering-Plough Reports Top-Line Results of the IDEAL Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... RALEIGH, N.C. , Dec. 23, 2014  Endo ... ENDP ) (TSX: ENL), and BioDelivery Sciences ... that they have submitted a New Drug Application (NDA) ... and Drug Administration (FDA).  Buprenorphine HCl Buccal Film is ... to require daily, around-the-clock, long-term opioid treatment and for ...
(Date:12/22/2014)... LAWRENCE, Mass. , Dec. 22, 2014 /PRNewswire/ ... a leading manufacturer of innovative dialysis products, announced ... (FDA) has cleared its System One™ to perform ... sleeping, known as home nocturnal hemodialysis. NxStage,s® System ... cleared by the FDA for this indication. ...
(Date:12/22/2014)... 2014   TRU-D SmartUVC LLC, producers of ... announced today that the General Services Administration has awarded ...   This newly formed agreement will allow ... government purchasers, including Department of Veteran Affairs and Department ... contacts purchasing solutions for the Ebola effort in ...
Breaking Medicine Technology:Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 2Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 3Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 4Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 5NxStage Receives FDA Clearance for Home Nocturnal Hemodialysis 2NxStage Receives FDA Clearance for Home Nocturnal Hemodialysis 3TRU-D SmartUVC LLC Awarded General Services Administration Contract to Expand Government Customer Base 2
... , Study Discussed at the American Podiatric Medical ... Md., July 30 Foot complications, such as open wounds and ulcers, ... treat. However, a new wound dressing powder, which acts very much ... and reduce the amount of pain that a patient suffering from a ...
... , PHILADELPHIA, July 29 Pediatric researchers ... the development of type 2 diabetes also predisposes children to having ... genetic influence on how prenatal events may set the stage for ... Researchers from The Children,s Hospital of Philadelphia and the University ...
Cached Medicine Technology:New Powder Speeds Healing of Difficult Foot Wounds 2Diabetes Gene Raises Odds of Lower Birth Weight 2Diabetes Gene Raises Odds of Lower Birth Weight 3
(Date:12/25/2014)... iFitDress.com, the popular online supplier of wedding dresses and special ... black one-shoulder cocktail dresses . In addition, all these ... discounted prices, up to 70% off. , The ... only. You know, we have thousands of frequent callers in ... items can visit our website for more details. The current ...
(Date:12/25/2014)... BambooFlooringChina.com sells many bamboo products and the ... the company announces big discounts on its bamboo ... , BambooFlooringChina.com is the world’s leader in bamboo flooring. ... until Jan. 20, 2015. , The bamboo mats are ... natural thread. All the bamboo strips for the mats ...
(Date:12/25/2014)... HealthDay Reporter WEDNESDAY, Dec. 24, ... illnesses can receive effective, less expensive care from a clinic ... a team of dedicated health care professionals, a new study ... and need either hospitalization or a trip to the emergency ... clinic at the University of Texas in Houston versus usual ...
(Date:12/25/2014)... By Dennis Thompson ... -- Researchers could be closing in on a "fountain of ... improve the health of older adults, a new study suggests. ... when given a drug that targets a genetic signaling pathway ... maker Novartis report. The experimental medication, a ...
(Date:12/25/2014)... (PRWEB) December 25, 2014 Plugin creators ... ProFire 5k. A fully customizable business presentation tool made ... “Adding the ProFire 5k business tool, users can now ... Austin, CEO of Pixel Film Studios. “ProFire 5k gives ... style to add professionalism to a presentation” , Pixel ...
Breaking Medicine News(10 mins):Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2Health News:Coordinated Care Through 'Medical Home' Best for Chronically Ill Kids: Study 2Health News:Coordinated Care Through 'Medical Home' Best for Chronically Ill Kids: Study 3Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 2Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 3Health News:Announcing a new ProFire 5k plugin from Pixel Film Studios for Final Cut Pro X Professionals 2
... Housing NYC,s Homeless & Mentally IllNEW YORK, April 29 ... shed light on it, philanthropic-minded New Yorkers will raise ... the mentally ill and physically disabled. As federal ... health services in the current economy, supporters will raise ...
... In a press release issued by the PEW ... that they have issued a letter to the Food ... the potential environmental threats related to the discharge of ... the human health risk allegedly resulting from the medical ...
... efforts and dedication of Santa Clarita County. Dr. Khanna newest procedure ... ... (Vocus) April 29, 2009 -- Recently, The Khanna Institute ... several surgeries, educational books, autographed t-shirts and various merchandise. This is ...
... Inc. is participating in the 2009 American College of Physicians, EHR ... and realize positive clinical and financial impacts. , ... ... Inc. is participating in the 2009 American College of Physicians, ...
... and productivity, announced today that Emergency Consultants, Inc. (ECI), a ... to the LearnCenter platform to offer Continuing Medical Education (CME) ... ... (PRWEB) April 29, 2009 -- Learn.com ®, ...
... Minn., April 29 Minnesota, which has long scored well ... Report, earning mostly solid "A" and "B" grades for air ... scored, fared much more poorly in this year,s report. ... pollution, enacted last year.Three counties, Anoka, Mille Lacs and Wright, ...
Cached Medicine News:Health News:Weston United Celebrates Mental Health Month on May 19th 2Health News:Salmon of the America's Responds to PEW Environmental Group 2Health News:Dr. Khanna Supports a Taste of Town in Santa Clarita 2Health News:Prime Clinical Systems Participating in American College of Physician's EHR Partners Program 2Health News:Prime Clinical Systems Participating in American College of Physician's EHR Partners Program 3Health News:Emergency Consultants Inc. switches to Learn.com to deliver Continuing Medical Education (CME) courses to physicians 2Health News:Emergency Consultants Inc. switches to Learn.com to deliver Continuing Medical Education (CME) courses to physicians 3