Navigation Links
Roche and Pharmasset To Present the R7128 Monotherapy Resistance Profile
Date:2/6/2008

NA. There was no evidence of the selection of PSI-6130 resistant virus in any dose cohort during the 2 weeks of dosing.

The preliminary results of a 4 week Phase 1 clinical trial to evaluate two oral dose levels of R7128 in combination with Pegasys(R) (pegylated interferon) plus Copegus(R) (ribavirin) in 50 treatment-naive patients chronically infected with HCV genotype 1 demonstrated potent short-term antiviral activity. Eighty-five (85%) of patients receiving R7128 1500mg and Pegasys plus Copegus (n=20) achieved undetectable HCV RNA levels following 4 weeks of treatment, or rapid virologic response. The R7128 combination cohorts demonstrated safety and tolerability comparable to placebo with Pegasys plus Copegus.

About Pharmasset

Pharmasset is a clinical-stage pharmaceutical company committed to discovering, developing and commercializing novel drugs to treat viral infections. Pharmasset's primary focus is on the development of oral therapeutics for the treatment of hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV).

Pharmasset is currently developing three product candidates. Clevudine, for the treatment of chronic HBV infection, is enrolling Phase 3 clinical trials for registration in North, Central and South America and Europe. Clevudine is already approved for HBV in South Korea and marketed by Bukwang Pharmaceuticals in South Korea under the brand name Levovir. R7128, an oral treatment for chronic HCV infection, is in a 4-week Phase 1 clinical trial in combination with Pegasys plus Copegus through a strategic collaboration with Roche. Racivir, which is being developed for the treatment of HIV in combination with other approved HIV drugs, has completed a Phase 2 clinical trial.

Pegasys(R) and Copegus(R) are registered trademarks of Roche.

Forward-Looking Statements

Pharmasset "Safe Harbor" Statement under the Private Securities Litigation Reform Act of 1995: Statements in thi
'/>"/>

SOURCE Pharmasset, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Roche responds to announcement of IDEAL hepatitis C trial results
2. Roche Submits Application for FDA Approval of ACTEMRA(R) for the Treatment of Rheumatoid Arthritis
3. Two Pivotal Phase III Studies for Roches ACTEMRA(TM) (tocilizumab) Demonstrate Significant Improvement in Rheumatoid Arthritis Symptoms
4. Roches Investigational Polymerase Inhibitor, Combined with PEGASYS(R) and COPEGUS(TM), Shows Potent Antiviral Activity in Treatment of Chronic Hepatitis C at Four Weeks
5. Roche Diagnostics HIV Viral Load Test Used in Clinical Trials for Isentress, a New Class of HIV Drug
6. Roche Announces Positive Results in Solid Tumors Using Human Monoclonal Antibody Against IGF-1R (R1507)
7. MacroChem Acquires Rights to Pexiganan, a Novel Topical Anti-Infective for Treatment of Diabetic Foot Infections, From Genaera
8. Rochester Medical Anti-Infection Foley Catheter Demonstrates Effectiveness in Randomized Trial
9. Researchers Identify Virus Possibly Responsible for Declining Honeybee Population Using 454 Sequencing Technology from Roche
10. Wyeths Torisel and Roche/Genentechs Avastin Will Challenge Pfizers Sutent to Become the Clinical Gold Standard for Treatment of Metastatic Renal Cell Carcinoma
11. Pharmasset Announces R7128 Achieves 85% Rapid Virologic Response in a 4-week Combination Study for the Treatment of Chronic Hepatitis C
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... 23, 2014 Research and Markets ... "Prepackaged Medical Kits and Trays - Global Strategic ... http://photos.prnewswire.com/prnh/20130307/600769 ... Medical Kits and Trays in US$ Thousands by ... Custom Trays, Custom Basin Kits, Custom Ob/Gyn Kits, ...
(Date:7/23/2014)... Calif. , July 23, 2014 Pelvalon, ... AUGS/IUGA Scientific Meeting in Washington, D.C. ... pivotal study of the Pelvalon,s Vaginal Bowel Control (VBC) ... of the Division of Urogynecology and Pelvic Reconstructive Surgery ... Past President of the Society for Gynecological Surgeons (SGS), ...
(Date:7/23/2014)... CALABASAS, Calif. , July 23, 2014 /PRNewswire/ ... developing revolutionary therapies to treat severe neurological disorders, ... worldwide licensing and collaboration agreement with Shire plc ... (ERT) for potential treatment of both the central ... Hunter syndrome. Also known as MPS II, Hunter ...
Breaking Medicine Technology:Prepackaged Medical Kits and Trays - Global Strategic Business Report: Updated 2014 Report 2Pelvalon Announces Results from the LIFE Pivotal Trial at the 2014 AUGS/IUGA Conference 2ArmaGen Announces Strategic Licensing and Collaboration Agreement with Shire to Develop AGT-182 for Treatment of Hunter Syndrome 2ArmaGen Announces Strategic Licensing and Collaboration Agreement with Shire to Develop AGT-182 for Treatment of Hunter Syndrome 3
... -- ShangPharma Corporation (NYSE: SHP ) ("ShangPharma" or ... development outsourcing company, today announced that it will release its ... 31, 2011 on May 19, 2011. Management will host a ... Time on May 19, 2011 (8:00pm Beijing time on May ...
... NANJING, China, May 9, 2011 /PRNewswire-Asia/ -- Simcere ... SCR ), a leading pharmaceutical company specializing ... and proprietary pharmaceuticals in China, today announced that ... in which it holds a 35% equity interest, ...
Cached Medicine Technology:ShangPharma Corporation to Announce First Quarter 2011 Financial Results on May 19, 2011 2Simcere Announces Recent Progress of Qiangke's Registration 2
(Date:7/23/2014)... month of July, LunaDress, a well-known wedding dress manufacturer and ... hosting a couple of promotions on its website. Recently, the ... wedding dresses for the UK market . The fresh range ... are now offered with huge discounts, from 20 to 70 ... suppliers, LunaDress is always making full efforts to offer classy ...
(Date:7/23/2014)... FL (PRWEB) July 23, 2014 As the ... burned more slowly resulting in old muscle being replaced by ... this excess fat in the belly region, the most dangerous ... visceral fat, actually surrounds the internal organs and circulates through ... weight related conditions. , For this reason, Diet Doc’s ...
(Date:7/23/2014)... Being overweight is no longer a mere cosmetic ... a diet high in processed and sugar-laden foods significantly ... a host of diseases and weight related conditions, including ... , The body makes cholesterol, as well as ... hard plaque to build up, clogging the arteries and ...
(Date:7/23/2014)... July 23, 2014 World Gardens Café, ... prepared healthy gourmet cuisine, received rave reviews last week ... Largest Mixer. Mixer attendees were amazed that healthy food ... 2014, World Gardens Café, the premier provider of delicious ... a booth at Dave Linden’s LA’s Largest Mixer. Attendees ...
(Date:7/23/2014)... 23, 2014 Princeview Dental ( http://www.PrinceviewDental.com ... the importance of having a complete oral exam. , ... to ensure oral health care, as there are so ... Janice Mummery, founder of Princeview Dental. “Dentists are trained ... to see. Just by observing the inside of the ...
Breaking Medicine News(10 mins):Health News:LunaDress Continues To Enrich Product Line By Offering Short Summer Beach Wedding Dresses 2Health News:Diet Doc Medical Weight Loss Programs Announces Exclusive Diet Plans for Men that are Simple, Easy to Follow and Melt Dangerous Belly Fat 2Health News:Diet Doc Medical Weight Loss Programs Announces Exclusive Diet Plans for Men that are Simple, Easy to Follow and Melt Dangerous Belly Fat 3Health News:Diet Doc’s Medical Weight Loss Programs Introduce Specialized Cholesterol Diet Plans that Deliver Fast Weight Loss and Reduce the Risk for Heart Attack and Stroke 2Health News:Diet Doc’s Medical Weight Loss Programs Introduce Specialized Cholesterol Diet Plans that Deliver Fast Weight Loss and Reduce the Risk for Heart Attack and Stroke 3Health News:Healthy Food Gets Rave Reviews at LA’s Largest Mixer 2Health News:Princeview Dental, One of Etobicoke’s Trusted Dental Clinics, Addresses the Need to Have Complete Oral Exams 2
... Solutions study outlines plan to help,primary care doctors ... Feb. 6 Primary care physicians,should exert broader ... compensated accordingly for their enhanced role in overall ... for Health Solutions,( http://www.deloitte.com/centerforhealthsolutions ) concludes., In ...
... Health Stewardship Project to release health care,reform ... WASHINGTON, Feb. 6 The Aspen ... care reform,principles that will enrich the health ... the proposed policies as candidates and policymakers ...
... BIRMINGHAM, Ala., Feb. 6 Emageon Inc.,(Nasdaq: ... technology,systems for hospitals, healthcare networks and imaging facilities, ... quarter and full year,2007 financial results on Thursday, ... company anticipates that these results will be available ...
... Coincides With National and Local News on these Issues, ... got a call from the police that her husband had ... own, she knew she had to,take action. Her husband, LaVern, ... Alzheimer,s disease in 2004, but this time the,situation had really ...
... UC Davis Collaboration, RANCHO CORDOVA, Calif., Feb. ... leading supplier of innovative products and,services that process ... disease,and injury, today announced a regenerative medicine initiative ... a wholly-owned subsidiary, Vantus, Inc., a,veterinary stem cell ...
... of multiple risk factors at once, , , WEDNESDAY, Feb. ... are already showing signs of some kidney damage may be ... multiple risk factors at once. , That,s the conclusion ... issue of the New England Journal of Medicine , ...
Cached Medicine News:Health News:The Medical Home: Building a Framework of Higher Quality, Reduced Cost and Patient-Centric Care 2Health News:The Medical Home: Building a Framework of Higher Quality, Reduced Cost and Patient-Centric Care 3Health News:Access Is Not Enough: What It Will Take to Transform Health Care in the United States 2Health News:Emageon Inc. to Host Fourth Quarter 2007 Financial Results Conference Call February 21, 2008 2Health News:Caregiver Magazine Urges Preventive Measures Against Wandering, Falls, Abuse 2Health News:Caregiver Magazine Urges Preventive Measures Against Wandering, Falls, Abuse 3Health News:Thermogenesis Announces New Initiative to Address Veterinary Regenerative Medicine 2Health News:Thermogenesis Announces New Initiative to Address Veterinary Regenerative Medicine 3Health News:Thermogenesis Announces New Initiative to Address Veterinary Regenerative Medicine 4Health News:Aggressive Diabetes Therapy Lowers Death Risk, Study Finds 2Health News:Aggressive Diabetes Therapy Lowers Death Risk, Study Finds 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: