Navigation Links
Risedronate Reduced Risk of Fracture Among Osteoporotic Postmenopausal Women with History of Hip Fracture
Date:9/17/2007

HONOLULU, Sept. 17 /PRNewswire-FirstCall/ -- In a new analysis reported at the American Society for Bone and Mineral Research (ASBMR) 29th Annual Meeting, risedronate 5 mg decreased clinical fracture risk by 50% over three years relative to placebo in a group of postmenopausal women with osteoporosis who had suffered a previous hip fracture. This retrospective analysis of the risedronate HIP trial(1) evaluated the combined incidence of vertebral and nonvertebral clinical fractures among this high risk group of patients.

"As physicians we want assurance that a therapy is effective at treating varying severities of disease," said Michael McClung, M.D., Founding Director of the Oregon Osteoporosis Center in Portland and a primary investigator of the study. "In this analysis risedronate effectively reduced fracture risk among patients with severe osteoporosis."

According to the National Osteoporosis Foundation, a history of prior fracture is an important risk factor for future fracture. After a postmenopausal woman suffers a hip fracture, her risk approximately doubles for sustaining another fracture.

"These at-risk patients need to be identified and considered for therapy that can help prevent another fracture from occurring," said Dr. McClung.

About the Analysis

In the HIP trial(1), there were 339 postmenopausal women between ages 70-79 years with low bone mineral density (BMD) and a history of at least one hip fracture prior to the study. These patients were treated with either placebo (PLC) or risedronate (RIS) 2.5 mg or 5 mg daily. Over the 3 year period, the clinical fracture incidences were 28.4%, 14.9% and 13% for the PLC, RIS 2.5 mg and RIS 5 mg groups, respectively. This corresponds to a 50% reduction in clinical fracture risk relative to placebo for both the 2.5 mg and 5 mg treatment groups (p=0.031 and p=0.048, respectively).

The incidence of osteoporosis-related clinical fracture, defined by the occurrence of radio
'/>"/>

SOURCE The Alliance for Better Bone Health
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
2. Publication on Pixantrone Preclinical Studies Demonstrates Reduced Cardiotoxicity Compared to Equiactive Doses of Doxorubicin and Mitoxantrone
3. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
4. Lipitor Reduced the Risk of Coronary Events by Half and Stroke by Nearly One-Third in High-Risk Patients with Type 2 Diabetes Who Experienced a Recent Stroke
5. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
6. Arterial Plaque Significantly Reduced in Women Age 50-59 Taking Hormones, Says New Analysis of Womens Health Initiative Data
7. New Analysis of WHI Data Shows Reduced Levels of Coronary Artery Calcification, a Predictor of Cardiovascular Events, in Women aged 50-59 taking Estrogen Therapy
8. Pivotal Phase III Trial Showed Promacta (eltrombopag olamine) Raised Platelet Counts and Reduced Bleeding in Patients With Chronic ITP
9. Preclinical Study Finds Protease Inhibitor-Resistant HIV May Have Reduced Potential to Develop Resistance to Panacos Bevirimat
10. New Analysis of Data Shows Treatment With Abbotts Humira (Adalimumab) Significantly Reduced Disease-Related Hospitalization for Patients with Crohns Disease
11. Data Suggest Cymbalta Reduced Severity of Night Pain in Patients with Diabetic Nerve Pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2015)... , April 24, 2015  Elekta has CE marked ... treatment planning system , enabling European clinics to deliver ... treatment techniques including advanced 3D planning, IMRT, VMAT and ... Monaco ® ... improved workflow efficiency. Advancements in 3D planning as well ...
(Date:4/23/2015)...  Edwards Lifesciences Corporation (NYSE: EW ), the ... hemodynamic monitoring, today reported net income for the quarter ... diluted share.  Net income for the same period a ... share, and non-GAAP net income was $82.1 million, or ... the quarter ended March 31, 2015 increased 13.0 percent to ...
(Date:4/23/2015)... 23, 2015 /CNW/ - Health Canada is working with ... update the safety information regarding the risk of serious ... these products are used at high doses (at or ... duration of use. Ibuprofen is a non-steroidal ... and to reduce inflammation. The majority of ibuprofen products ...
Breaking Medicine Technology:Elekta CE marks for Monaco v5.10 treatment planning system 2Edwards Lifesciences Reports First Quarter Results 2Edwards Lifesciences Reports First Quarter Results 3Edwards Lifesciences Reports First Quarter Results 4Edwards Lifesciences Reports First Quarter Results 5Edwards Lifesciences Reports First Quarter Results 6Edwards Lifesciences Reports First Quarter Results 7Edwards Lifesciences Reports First Quarter Results 8Edwards Lifesciences Reports First Quarter Results 9Edwards Lifesciences Reports First Quarter Results 10Edwards Lifesciences Reports First Quarter Results 11Edwards Lifesciences Reports First Quarter Results 12Edwards Lifesciences Reports First Quarter Results 13Edwards Lifesciences Reports First Quarter Results 14Edwards Lifesciences Reports First Quarter Results 15Edwards Lifesciences Reports First Quarter Results 16Information Update - New safety information for prescription-strength ibuprofen: Risk of heart attack and stroke at high doses 2Information Update - New safety information for prescription-strength ibuprofen: Risk of heart attack and stroke at high doses 3Information Update - New safety information for prescription-strength ibuprofen: Risk of heart attack and stroke at high doses 4
... 2011 Texas Institute of Dermatology, Laser and Cosmetics is ... including San Antonio and Boerne area to treat superficial vascular ... "I,m very excited to add this new service for our ... Laser and Cosmetics. "As a long time provider of aesthetic ...
... SAN DIEGO, Feb. 1, 2011 CareFusion Corporation ... announced today the appointment of Kieran T. Gallahue as chairman ... announced plans to retire later this month. A ... and CEO of ResMed (NYSE: RMD ), a ...
Cached Medicine Technology:San Antonio's Texas Institute of Dermatology, Laser and Cosmetics Adds Alma Lasers Harmony XL Cosmetic Laser to Offer Advanced Rejuvenation Treatments to Patients 2CareFusion Names Kieran T. Gallahue Chairman and CEO 2CareFusion Names Kieran T. Gallahue Chairman and CEO 3
(Date:4/24/2015)... 2015 Anchor Health Administrators (Anchor), specialists ... today announced their exclusive agreement with LTC Solutions for ... Insurance distribution partner. , Anchor has more than 18 ... benefits for associations, and is currently the designated advocate ... Term Care Insurance member benefit. , “I am very ...
(Date:4/24/2015)... 24, 2015 “Kind,” “selfless,” “the voice ... the ways Denise Weiner described pediatric oncology nurse Laura ... her daughter, Alexa, during her five-year battle with a ... bone marrow transplant and numerous experimental treatments, Vasquez continued ... Alexa when she was not in the hospital and ...
(Date:4/24/2015)... ON (PRWEB) April 24, 2015 ... safe, informed and legal access to medical cannabis, is ... are properly supported when advising patients. , NAC is ... Certificate Program. With a $250,000 grant, NAC will be ... program. , "Our goal is to help Canadians gain ...
(Date:4/24/2015)... MMJ Physician Practice in Salem, ... to enroll in the Massachusetts medical marijuana program.    Their ... away from Alternative Therapies Group (ATG), the first ... summer. With the dispensary nearby, MMJ Physician ... for residents of eastern Massachusetts to enroll in ...
(Date:4/24/2015)... WA (PRWEB) April 24, 2015 ... health management organizations, has published a new resource ... Improvement Guide.” The guide to Quality and Resource ... for Medicaid & Medicare Services (CMS) to help ... of care, streamline resources, and identify care coordination ...
Breaking Medicine News(10 mins):Health News:CURE™ Magazine Names Pediatric Nurse Laura Vasquez from Children’s Hospital Los Angeles As Extraordinary Healer™ of 2015 2Health News:CURE™ Magazine Names Pediatric Nurse Laura Vasquez from Children’s Hospital Los Angeles As Extraordinary Healer™ of 2015 3Health News:CURE™ Magazine Names Pediatric Nurse Laura Vasquez from Children’s Hospital Los Angeles As Extraordinary Healer™ of 2015 4Health News:National Access Cannabis Gives 300 Canadian Healthcare Professionals Access to Medical Cannabis Certificate Program 2Health News:Medical Doctor from Salem Massachusetts Supports the Medical Marijuana Industry 2Health News:Qualis Health Publishes Guide to Help Physician Practices Assess and Improve Quality 2
... At the request of the presidential transition team, ... package were provided today by the American College of ... physicians and medical student members. It is the ... second largest physician membership organization. , "ACP believes that ...
... Pyramid Developers, a leader in the planning and development ... joined with Scottsdale based Dr. Theresa Ramsey,s Center For Natural ... Of the People" reflecting the focus of the collaboration - ... wellness focused sustainable communities. , , ...
... consistently outperform women on spatial tasks, including mental rotation, ... object would appear if rotated in space. Now, a ... sex-linked ability and the structure of the parietal lobe, ... , The parietal lobe was already known to differ ...
... , BETHESDA, Md., Dec. 17 ... the Cystic Fibrosis Foundation, today announced its 20th anniversary of ... nationwide. , , The organization ... a mission to improve access to specialty medications for people ...
... wake of the historic economic crisis and just days before ... and other thought leaders will gather at the University ... energy demand, health care, the environment and other issues related ... Business Forum, presented by the John S. and James L. ...
... It,s time patient consent forms came back full circle to ... liability they have become. The original purpose of the consent ... patient of common or serious risks associated with the procedure ... written as formal, legal documents plants a litigious ...
Cached Medicine News:Health News:Internists ask President-elect Obama to include aid for primary care in stimulus proposal 2Health News:Internists ask President-elect Obama to include aid for primary care in stimulus proposal 3Health News:Pyramid Developers and Dr. Ramsey's Center for Natural Healing Announce Formation of Community Health and Wellness Planning Collaborative. 2Health News:Pyramid Developers and Dr. Ramsey's Center for Natural Healing Announce Formation of Community Health and Wellness Planning Collaborative. 3Health News:Pyramid Developers and Dr. Ramsey's Center for Natural Healing Announce Formation of Community Health and Wellness Planning Collaborative. 4Health News:Sex difference on spatial skill test linked to brain structure 2Health News:Cystic Fibrosis Services Pharmacy Celebrates 20th Anniversary 2Health News:Top CEOs and Other Executives Gather in Miami to Address Economic Crisis, Alternative Energy, Health Care and More 2Health News:Top CEOs and Other Executives Gather in Miami to Address Economic Crisis, Alternative Energy, Health Care and More 3Health News:Patient consent forms should educate not intimidate 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: