Navigation Links
Revalesio Presents Data Showing RNS60 Alters Disease Progression in Animal Model of Alzheimer's Disease Through the PI3k-Akt Pathway
Date:7/18/2013

TACOMA, Wash., July 18, 2013 /PRNewswire/ -- On Wednesday Revalesio Corporation presented new data at the Alzheimer's Association International Conference that identifies the specific cellular pathways by which Revalesio's lead investigational product, RNS60, impacts Alzheimer's Disease. This research, conducted in partnership with Rush University Medical Center, investigates a new category of therapeutics using Revalesio's novel nanotechnology platform.

Data presented at the conference demonstrated RNS60's ability to prevent memory loss and improve learning through the PI3k-pAKT pathway.  Additionally, RNS60 upregulates critical genes associated with neuronal plasticity.  These genes play a key role in healthy neurotransmitter and synaptic function, foundational activities of the brain. 

Defining RNS60's activity against these genes is an important link between the significant therapeutic activity demonstrated by RNS60 in mouse and cellular models where RNS60 prevented beta-amyloid induced cell death and tau-neurofibrillary tangles – the most common hallmarks of Alzheimer's disease.

"The ability to define RNS60's biological activity to these plasticity associated genes and the PI3k-pAKT-CREB-BDNF pathway is an important event for the company," said Dr. Richard Watson, Revalesio's Chief Science Officer.  "We have a large and expanding data set on RNS60's ability to reduce inflammation, and these findings are a significant advancement in our understanding of how RNS60 may be a treatment for neuro-degenerative diseases."

These plasticity associated genes and associated pathways have long been targets for drug developers, but Revalesio's approach through its charge-stabilized nanostructure technology provides a new paradigm for treating Alzheimer's disease.  Revalesio and its research partners at Rush University Medical Center have submitted the data fo
'/>"/>

SOURCE Revalesio Corporation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Dr. Helen Fisher to Speak at Astellas Presents Executive Womens Day at the Constellation SENIOR PLAYERS Championship
2. Molly Fletcher to Speak at Astellas Presents Executive Womens Day at the AT&T National
3. Lexicon Presents Data at the American Diabetes Association Meeting On Blood Pressure Reduction and Weight Loss In Clinical Trial of LX4211
4. Lexicon Presents Preclinical Data On LX2761, a New Clinical Candidate for Diabetes Designed to Reduce Glucose Absorption From Gastrointestinal Tract
5. Nektar Therapeutics Presents Positive Data from Human Abuse Liability Study for NKTR-181, a First-in-Class Investigational Opioid to Treat Chronic Pain, at 2013 Annual Meeting of The College on Problems of Drug Dependence
6. Pharma IQ Presents the Latest Trends in Clinical Trial Supply
7. Adamas Pharmaceuticals Presents Positive Phase 2/3 Results For ADS-5102 For The Treatment Of Levodopa-Induced Dyskinesia (LID) In Parkinsons Disease
8. Vanda Presents Data From Phase III Studies that Demonstrate Tasimelteon Restores Daily Cortisol Rhythm In Blind Patients With Non-24-Hour Disorder
9. AbbVie Presents Preliminary Results from Phase I Study of Investigational Oncology Compound ABT-199/GDC-0199 in Patients with High-Risk Chronic Lymphocytic Leukemia (CLL) at European Hematology Association Annual Meeting
10. Bluestar Silicones Presents Elastomer Solutions At Medical Design And Manufacturing (MD&M) East Show
11. Discovery Labs Presents Final Assessment in a Series of Pharmacoeconomic Analyses that Explore Impact of Reintubation on Healthcare Costs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... ATLANTA , Jan. 23, 2015 More than a ... a quarter of those with private insurance, filled a prescription ... to a report in this week,s Morbidity and Mortality Weekly ... health care providers to treat moderate to severe pain.  They ...
(Date:1/23/2015)...  Now available for sale, The Armor1 Ankle Roll Guard is ... sprains by cushioning the ankle from an inversion or ... outside of any shoe type and allows the user ... protection against sprains. With customers in physical therapy, podiatry, ...
(Date:1/23/2015)... , Jan. 23, 2015  CytoSorbents Corporation (NASDAQ CM: ... CytoSorb® extracorporeal cytokine adsorber to reduce deadly inflammation ... receipt of $385,642, net of transaction costs, in ... Technology Business Tax Certificate Transfer Program sponsored by ...
Breaking Medicine Technology:Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 3
... and NUREMBERG, Germany, April 13, 2012 ... of mobile C-arms presents its award-winning product portfolio ... Together with Xograph ( http://www.xograph.com ), its UK ... vascular specialists, interventional radiologists and cardiologists to provide ...
... ("Unilife" or "Company") (NASDAQ: UNIS ;  ASX: UNS) announced ... fiscal 2012 third quarter ended March 31, 2012 after market trading ... scheduled a conference call for 4:30 p.m. U.S. EDT on Thursday, ... AM AEST) , to review the Company,s financial results, market ...
Cached Medicine Technology:CX 2012: Elevating the Boundaries of Interventional Imaging with Mobile C-arms 2Unilife Corporation to Announce Financial Results for Fiscal 2012 Third Quarter on Thursday, April 26, 2012 2Unilife Corporation to Announce Financial Results for Fiscal 2012 Third Quarter on Thursday, April 26, 2012 3
(Date:1/22/2015)... 22, 2015 EBSCO Information Services ... expanding their relationship in an effort to further promote visibility ... While EBSCO has long made AMA journals available via its ... for The JAMA Network. , Long known as ...
(Date:1/22/2015)... is a famous dress online store for wedding dresses and ... collection of wedding dresses , and launches a site-wide women’s ... dress on your big day; the wedding gown is the ... to find the most suitable wedding dress. Now, we are ...
(Date:1/22/2015)... released a new blog post explaining the importance of keeping a ... of an auto insurance policy . , Clients who driver ... their vehicle insurance policies. The safety a vehicle offers from its ... of this, drivers should always carry a first aid kit in ...
(Date:1/22/2015)... State Forestry Institute of Mecklenburg-Vorpommern in Germany ... from GEOSYSTEMS, a dedicated Hexagon Geospatial and Intergraph partner ... Geospatial’s ERDAS APOLLO for cataloging, managing, and ... clouds and documents. This effort will enable the State ...
(Date:12/26/2014)... 2014 It is said that nothing makes ... UWDress.com, the famous wedding dress supplier, shows its new ... cocktail gown promotion. , UWDress.com’s navy cocktail gowns are ... come in high fashion styles. Simple dresses in bright neon ...
Breaking Medicine News(10 mins):Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2Health News:Driving Safe And Other Factors That Make Auto Insurance Affordable! 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 3Health News:UWDress.com Shows Its New Navy Cocktail Dresses For 2015 2
... -- The World Health Organization ... announced the launch of a Joint Programme on Cancer ... cancer in the developing world. , The groundbreaking agreement ... and its projected increase. Latest statistics indicate that cancer ...
... of life, one thing is certain: there,s no place like ... finds the same is true for rats. Although inner ... where they spend the majority of their lives. , Like ... with its own personality. But scientists from the Johns Hopkins ...
... quickly and consistently WASHINGTON, May 26 As the ... many U.S. school and government leaders used notification technology ... and information - the latest example of the way ... when it might have taken officials days to reach ...
... Oral Therapies Will Garner 29 Percent of the Total ... Decision ResourcesWALTHAM, Mass., May 26 Decision Resources, one ... pharmaceutical and healthcare issues, finds that the approval and ... the increasing use of current and emerging injectable drugs ...
... in jeopardy, study finds , , TUESDAY, May 26 (HealthDay ... whooping cough, those who aren,t vaccinated are 23 times ... that shows the danger faced by children whose parents ... the conclusion of researchers who reviewed the health records ...
... at 1:00 PM ET to Discuss ASCO Data Presentations ... Pharmaceuticals, Inc. (Nasdaq: SNSS ), a biopharmaceutical ... oncology therapeutics, today announced that updated interim data from ... acute myeloid leukemia (AML) and platinum-resistant ovarian cancer and ...
Cached Medicine News:Health News:WHO-IAEA join forces to fight cancer 2Health News:Schools and Cities Send 9.7 Million Messages During Swine Flu Outbreak with Blackboard Connect(TM) Platform 2Health News:Schools and Cities Send 9.7 Million Messages During Swine Flu Outbreak with Blackboard Connect(TM) Platform 3Health News:Schools and Cities Send 9.7 Million Messages During Swine Flu Outbreak with Blackboard Connect(TM) Platform 4Health News:Launch of Highly Anticipated Oral Agents and Increasing Use of Current and Emerging Injectable Drugs Will Drive the Multiple Sclerosis Drug Market to Nearly $10 Billion in 2018 2Health News:Launch of Highly Anticipated Oral Agents and Increasing Use of Current and Emerging Injectable Drugs Will Drive the Multiple Sclerosis Drug Market to Nearly $10 Billion in 2018 3Health News:Refusing Shots Puts Kids at Higher Risk for Whooping Cough 2Health News:Sunesis Announces New Data on Voreloxin for Acute Myeloid Leukemia and Ovarian Cancer Will Be Presented at ASCO 2Health News:Sunesis Announces New Data on Voreloxin for Acute Myeloid Leukemia and Ovarian Cancer Will Be Presented at ASCO 3Health News:Sunesis Announces New Data on Voreloxin for Acute Myeloid Leukemia and Ovarian Cancer Will Be Presented at ASCO 4
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: