Navigation Links
Retrospective Analysis Finds That Initiation of Insulin Glargine in Patients With Type 2 Diabetes was Associated With a Lower Incidence Rate of Myocardial Infarction as Compared With NPH Insulin
Date:11/7/2007

ORLANDO, Fla., Nov. 7 /PRNewswire-FirstCall/ -- A retrospective analysis of healthcare claims in more than 20,000 patients with type 2 diabetes from an integrated U.S. national managed care database found that the initiation of insulin therapy with insulin glargine was associated with a lower incidence rate of subsequent myocardial infarction (MI), as compared with NPH insulin. The new findings, presented at the American Heart Association's 2007 Scientific Sessions, are some of the first to evaluate the rate of MI in a database of patients treated with insulin glargine -- a commonly used drug in patients with type 2 diabetes for the control of hyperglycemia.

The unadjusted incidence rate of MI events was 11.5/per thousand patient- years in the group of patients treated with glargine and 17.6/per thousand patient-years in the group treated with NPH during an observation period up to 5 years with a mean about 2 years. The unadjusted hazard ratio for MI events was 0.640 (95% CI: 0.539 - 0.761). After adjusting for multiple patient factors, the risk of MI remained lower in the group of patients who initiated treatment with insulin glargine (HR: 0.73; 0.60 - 0.89) as compared with NPH insulin.

"While insulin glargine has become widely used for the control of hyperglycemia in patients with diabetes since its introduction, the post- market data on its long-term cardiovascular safety has been lacking until now," said Dr. Mikhail Kosiborod, a cardiologist at the Mid America Heart Institute in Kansas City, Missouri, and one of the lead authors of the study. "Although these findings need to be confirmed in future, prospective studies, they suggest that the use of insulin glargine is associated with lower risk of MI than NPH."

Further Studies Planned

The cardiovascular complications associated with diabetes are one of the most serious unmet needs in medicine today. This question is addressed by sanofi-aventis with a comprehensive program evaluatin
'/>"/>

SOURCE sanofi-aventis
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related medicine technology :

1. Trubion Announces Preliminary Analysis of Phase IIb Results With TRU-015 in Rheumatoid Arthritis
2. Oncology Drugs Development Update - Worldwide Markets and Forecasts of Approved EGFr/HEr2 Inhibitors, Treatment Costs, Pathway Analysis, Current and Expanded Clinical Indications, and Novel Agents in Development
3. New Data From Large Safety Analysis of MYCAMINE Shows Favorable Clinical Safety Profile
4. Immtech Announces Interim Analysis in Phase III African Sleeping Sickness Trial
5. Analysis Shows Vernakalant Hydrochloride Injection Increases Conversion to Normal Heart Rhythm in Acute Atrial Fibrillation Patients Treated Within 48 Hours of Onset
6. New Analysis of Study Data Shows That Asacol(R) (Mesalamine) Delivers Rapid Symptom Relief for Ulcerative Colitis Patients
7. A Sociolinguistic Analysis of In-Office Dialogue Reveals Psychiatrists and Parents Have Significantly Different Perceptions on ADHD and Psychiatric Comorbidities
8. Favrille Provides Update on Timing of Analysis from Pivotal Phase 3 Clinical Trial; Reports Third Quarter 2007 Financial Results
9. Results Of VYVANSE(TM) (lisdexamfetamine dimesylate) Effect Size Analysis Presented at Major Scientific Meeting
10. Progen Presents Additional Analysis of Data from PI-88 Phase 2 Liver Cancer Study at American Association for the Study of Liver Diseases
11. Replikins LLC Finds West Nile Virus Replikin Count Has Reached Its Highest Recorded Value
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)...  The need to add tissue preserving therapies ... prominently at the 108 th Annual Meeting ... Diego.  According to SonaCare Medical, a leader in ... the need for image-guided technologies to better identify ... minimally invasive ablative treatments, was addressed in the ...
(Date:5/23/2013)... 23, 2013  Texas, premier physician associations today announced ... survival tools they need to provide demonstrably better and ... care marketplace. "I am confident the Physician ... said Stephen L. Brotherton , MD, ... Texas doctors are determined to make health ...
(Date:5/23/2013)... May 23, 2013   Direct to implant, ... is an appropriate option for many women with ... reduce their breast cancer risk, or with breast ... process and a second surgery to insert permanent ... same surgery as mastectomy can be a medically ...
Breaking Medicine Technology:Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 2Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 3Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 4Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 5Need for Image Guided Minimally Invasive Ablative Treatments Featured Prominently at American Urological Association (AUA) Annual Meeting 6TMA Launches Physician Services Organization for Patient Care 2TMA Launches Physician Services Organization for Patient Care 3TMA Launches Physician Services Organization for Patient Care 4Direct to Implant ("One Step") Mastectomy Breast Reconstruction Reduces Number of Surgeries and Time to Final Cosmetic Results 2Direct to Implant ("One Step") Mastectomy Breast Reconstruction Reduces Number of Surgeries and Time to Final Cosmetic Results 3
... Nov. 10, 2010 The Halifax Health - Betty ... celebrated the beginning of a new decade of caring ... during a ceremony held this afternoon in Daytona Beach, ... and Halifax Health will celebrate the 10th anniversary of ...
... Everyday, a growing number of Americans depend on life-saving ... consumers better understand prescription drug choices, AARP and Consumer ... For the first time, people can use Consumers Union ... price, and receive tips on how to have a ...
Cached Medicine Technology:Speediatrics Unit Celebrates 10th Anniversary 2Speediatrics Unit Celebrates 10th Anniversary 3AARP, Health Publication Join to Create Online Tool to Help Manage Drug Decisions 2
(Date:5/26/2013)... Despite the recent mishaps and horror stories ... cruises go off without a hitch, providing tens of ... year. Across the boating industry, manufacturers have made today’s ... to cruise ships more powerful, safer and more luxurious. ... King will look at some of the many ...
(Date:5/25/2013)... Health food arose in China in ... food industry has formed with the value of ... the health food industry reached RMB110 billion, showing ... health food falls into Vitamin & Dietary Supplements, ... wherein, Vitamin & Dietary Supplements generate RMB62.5 billion, ...
(Date:5/25/2013)... 2013 According to an article in the ... Feeling,” nearly 30 million Americans tan indoors each year and ... despite knowing the health risks. New research suggests that ... effect on the brains of some tanners (Go to goo.gl/hdwnz). ... so I can’t say that I fully support this contention ...
(Date:5/25/2013)... (PRWEB) May 25, 2013 Dr. Leslie ... non-invasive procedure FDA-approved to lift skin on the neck, on ... at her practice, Medical Aesthetics. , Ultherapy is a non-surgical ... own natural healing process to lift the skin over time. ... first time, to see and then treat the deepest support ...
(Date:5/25/2013)... A disorder of the nerves, Diabetic ... According to neuropathy expert doctor Helen C Lin, on ... the disorder affects almost 50% of all Diabetic patients, ... The high blood sugar levels in the body are ... it usually tend to have abnormally high blood sugar ...
Breaking Medicine News(10 mins):Health News:The In View Series Announces Plans for a New Series About Boating 2Health News:China Health Food Industry Analysis and 2015 Forecasts in New Research Report at RnRMarketResearch.com 2Health News:Sun Damage – Are UV Rays Addictive? 2Health News:Dr. Leslie Gerstman Is Now Offering the Non-surgical Facelifting Procedure – Ultherapy – in NYC and NJ 2Health News:Diabetic Neuropathy treatment hits new grounds- Neuracel launches the complete natural treatment 2
... trial led by a Saint Louis University researcher, investigators found ... ribavirin helps some hepatitis C patients who have not responded ... of Hepatology , offer a new option for hepatitis ... with factors that make their condition difficult to treat. ...
... ... of supply chain and procurement services to hospital , ... Dallas (Vocus) June 16, 2009 -- Broadlane announced today ... supply chain management and procurement services to help manage its approximate $52 million in annual ...
... AIRES, Argentina, June 16 Most hospitals in Latin America ... the radiology departments - a reason to consider the process ... there arises a need to focus on awareness as a ... for digital radiography (DR). , , (Logo: ...
... ... now a featured expert on searchbloodsugar.com, a new informational Web site devoted to all aspects ... ... , a founder of the alternative health movement, is now a featured expert on searchbloodsugar.com, ...
... ... to hire 200 staff in Singapore, GSK and the Singapore Economic Development Board (EDB) ... ... higher gear, with the opening of a state-of-the-art vaccine plant. The new plant is ...
... ... Design engineers have always faced unique challenges in specifying force sensors, ... the market, from load cells to strain gauges to thin and flexible ... overwhelming. "Force Sensors for Design," a newly-published white paper from force ...
Cached Medicine News:Health News:Good news for some hard-to-treat hepatitis C patients 2Health News:Virginia Hospital Center Seeks to Reduce Operating Costs and Improve Supply Chain with Broadlane 2Health News:Virginia Hospital Center Seeks to Reduce Operating Costs and Improve Supply Chain with Broadlane 3Health News:Virginia Hospital Center Seeks to Reduce Operating Costs and Improve Supply Chain with Broadlane 4Health News:Virginia Hospital Center Seeks to Reduce Operating Costs and Improve Supply Chain with Broadlane 5Health News:Virginia Hospital Center Seeks to Reduce Operating Costs and Improve Supply Chain with Broadlane 6Health News:The Latin American Digital Radiography Market to Grow Significantly due to the Need to Improve Digital Adoption, Observes Frost & Sullivan 2Health News:The Latin American Digital Radiography Market to Grow Significantly due to the Need to Improve Digital Adoption, Observes Frost & Sullivan 3Health News:Dr. Julian Whitaker Featured on Searchbloodsugar.com 2Health News:Dr. Julian Whitaker Featured on Searchbloodsugar.com 3Health News:GlaxoSmithKline Opens $600million Vaccine Plant In Singapore 2Health News:GlaxoSmithKline Opens $600million Vaccine Plant In Singapore 3Health News:New White Paper Helps OEM Design Engineers Navigate the Force Transducer Selection Process 2
... Wampole Laboratories offers a comprehensive line of ... serum and urine in convenient one-step stick ... 2 testing options. Clearview Easy HCG is ... convenient stick format. Clearview HCG II ...
For the quantitative determination of Glycohemoglobin in blood....
The DSL-10-3000 ACTIVE Ferritin Enzyme-Linked Immunosorbent (ELISA) Kit provides materials for the quantitative measurement of ferritin in serum....
... Bio-Rad isotopic anemia assays ... minimal ,pipetting steps for ... about the processes ,involved ... the benefit to your ...
Medicine Products: