Navigation Links
Retrospective Analysis Finds That Initiation of Insulin Glargine in Patients With Type 2 Diabetes was Associated With a Lower Incidence Rate of Myocardial Infarction as Compared With NPH Insulin
Date:11/7/2007

ORLANDO, Fla., Nov. 7 /PRNewswire-FirstCall/ -- A retrospective analysis of healthcare claims in more than 20,000 patients with type 2 diabetes from an integrated U.S. national managed care database found that the initiation of insulin therapy with insulin glargine was associated with a lower incidence rate of subsequent myocardial infarction (MI), as compared with NPH insulin. The new findings, presented at the American Heart Association's 2007 Scientific Sessions, are some of the first to evaluate the rate of MI in a database of patients treated with insulin glargine -- a commonly used drug in patients with type 2 diabetes for the control of hyperglycemia.

The unadjusted incidence rate of MI events was 11.5/per thousand patient- years in the group of patients treated with glargine and 17.6/per thousand patient-years in the group treated with NPH during an observation period up to 5 years with a mean about 2 years. The unadjusted hazard ratio for MI events was 0.640 (95% CI: 0.539 - 0.761). After adjusting for multiple patient factors, the risk of MI remained lower in the group of patients who initiated treatment with insulin glargine (HR: 0.73; 0.60 - 0.89) as compared with NPH insulin.

"While insulin glargine has become widely used for the control of hyperglycemia in patients with diabetes since its introduction, the post- market data on its long-term cardiovascular safety has been lacking until now," said Dr. Mikhail Kosiborod, a cardiologist at the Mid America Heart Institute in Kansas City, Missouri, and one of the lead authors of the study. "Although these findings need to be confirmed in future, prospective studies, they suggest that the use of insulin glargine is associated with lower risk of MI than NPH."

Further Studies Planned

The cardiovascular complications associated with diabetes are one of the most serious unmet needs in medicine today. This question is addressed by sanofi-aventis with a comprehensive program evaluatin
'/>"/>

SOURCE sanofi-aventis
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Trubion Announces Preliminary Analysis of Phase IIb Results With TRU-015 in Rheumatoid Arthritis
2. Oncology Drugs Development Update - Worldwide Markets and Forecasts of Approved EGFr/HEr2 Inhibitors, Treatment Costs, Pathway Analysis, Current and Expanded Clinical Indications, and Novel Agents in Development
3. New Data From Large Safety Analysis of MYCAMINE Shows Favorable Clinical Safety Profile
4. Immtech Announces Interim Analysis in Phase III African Sleeping Sickness Trial
5. Analysis Shows Vernakalant Hydrochloride Injection Increases Conversion to Normal Heart Rhythm in Acute Atrial Fibrillation Patients Treated Within 48 Hours of Onset
6. New Analysis of Study Data Shows That Asacol(R) (Mesalamine) Delivers Rapid Symptom Relief for Ulcerative Colitis Patients
7. A Sociolinguistic Analysis of In-Office Dialogue Reveals Psychiatrists and Parents Have Significantly Different Perceptions on ADHD and Psychiatric Comorbidities
8. Favrille Provides Update on Timing of Analysis from Pivotal Phase 3 Clinical Trial; Reports Third Quarter 2007 Financial Results
9. Results Of VYVANSE(TM) (lisdexamfetamine dimesylate) Effect Size Analysis Presented at Major Scientific Meeting
10. Progen Presents Additional Analysis of Data from PI-88 Phase 2 Liver Cancer Study at American Association for the Study of Liver Diseases
11. Replikins LLC Finds West Nile Virus Replikin Count Has Reached Its Highest Recorded Value
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... CAESAREA, Israel , July 10, 2014 /PRNewswire/ ... Dario™ Diabetes Management Solution, today announced the appointment ... an independent member of its Board of Directors. ... of legal and business experience to LabStyle as ... director, and legal and corporate governance expert. He ...
(Date:1/15/2014)... N.Y. , Jan. 15, 2014 Sono-Tek Corporation (OTC ... months ended November 30, 2013, compared to sales of $2,202,000 ... 20%. Once again, this quarter has also shown growth over ... the first quarter of this fiscal year. Markets that experienced ...
(Date:1/15/2014)... 15, 2014  Research and Markets ( http://www.researchandmarkets.com/research/6k27gw/dental ) has ... - Global Industry Analysis, Size, Share, Growth, Trends And ... (Logo: http://photos.prnewswire.com/prnh/20130307/600769 ... on patients in order to treat dental impairments, for ...
Breaking Medicine Technology:LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 3LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 4Sono-Tek Announces Third Quarter Results 2Sono-Tek Announces Third Quarter Results 3Sono-Tek Announces Third Quarter Results 4Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3
... Recent Highlights ... Term loan repaid Revolving line of credit ... financial results announced Cogdell Spencer Inc. (the ... real estate partner, is a REIT focused on planning, owning, ...
... We are pleased to announce the launch of Laboratoryretriever.com ... of contract laboratory outsourcing and regulatory opportunities. ... to fulfill your contract laboratory testing and scientific ... outsourcing assignments. You also can post free for a limited ...
Cached Medicine Technology:Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 2Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 3Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 4Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 5Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 6Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 7Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 8Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 9Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 10Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 11Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 12Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 13Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 14Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 15Cogdell Spencer Announces Fourth Quarter 2010 Results and Completion of Strategic Plan 16Announcing New Contract Laboratory Testing and Outsourcing Web Database 2
(Date:7/11/2014)... B. E. Smith, the only full-service leadership ... to lead a national chief nursing officer search ... The top executive search firm in the healthcare ... healthcare executives into organizations. , With four hospitals and ... is the largest provider of medical care in Central Oregon. ...
(Date:7/11/2014)... 11, 2014 This is a ... of the Cholesterol industry in Global and China. ... industry, including definitions, applications and industry chain structure. ... are provided with a focus on history, developments, ... comparison between the international and Chinese situation is ...
(Date:7/11/2014)... old was thought of as a fate that was far worse ... that many of the “myths” people associate with aging ... elderly can still live quite as fruitfully as their younger counterparts ... the world, older people also need to live a kind of ... of their lives. This is why Guy Coalter, the founder of ...
(Date:7/11/2014)... (PRWEB) July 11, 2014 ... begin this August in New York. ... cover: , -Myofascial Trigger Point Therapy, ... -Mobilization & Thrust Manipulation, -Neuroobilization & Neurodynamics, ... prescribing to a single, isolated manual therapy ...
(Date:7/11/2014)... Mexico (PRWEB) July 11, 2014 People ... disorder are just some of the increasing numbers of ... to lead more independent and productive lives. , ... workplace? Or is an assistance dog an impediment to ... Dog Week , August 3 - 9, 2014, West ...
Breaking Medicine News(10 mins):Health News:St. Charles Health System Retains B. E. Smith to Recruit New CNO 2Health News:St. Charles Health System Retains B. E. Smith to Recruit New CNO 3Health News:Cholesterol Industry 2014 Development Trends in Global & China Regions in a New Research Study Available at DeepResearchReports.com 2Health News:Cholesterol Industry 2014 Development Trends in Global & China Regions in a New Research Study Available at DeepResearchReports.com 3Health News:It’s All Free For Seniors Review, How To Take Advantage of What Life Has to Offer In Old Age – Vinamy.com 2Health News:It’s All Free For Seniors Review, How To Take Advantage of What Life Has to Offer In Old Age – Vinamy.com 3Health News:Hands-On Seminars, the Leader in Manual Therapy Continuing Education, Announces Series of Comprehensive Hands-On Training Courses 2Health News:Will Your Next Employee or Co-Worker Be a Dog? 2Health News:Will Your Next Employee or Co-Worker Be a Dog? 3Health News:Will Your Next Employee or Co-Worker Be a Dog? 4
... in the human diet mean people today are more at ... said.Researchers at the University of Newcastle believe that changes to ... off its anti-cancer agents. ,The researchers are working ... in fighting stomach cancer. They are carrying out two trials ...
... an amino-acid taste receptor.Dr Charles S. Zuker, from ... of California, San Diego, reports his team's findings ... tastes — bitter, salty, sour, sweet, and umami. ... (MSG).Receptors that responded to umami have been discovered ...
... are associated with permutation in brain structure that appear ... conducted by researchers at the University of Iowa.// ... and 54 male control subjects, the researchers used magnetic ... They found that the volume of the anterior portion ...
... shun most of the dangers of developing lung cancer. There are ... are former smokers compared with those who continue to smoke.// Over ... lung cancer in the world. ,One of the authors ... study in 1950 established the smoking and lung cancer link. A ...
... pollutant emitted by power plants and vehicles raises the ... of dying from lung cancer or heart disease//, and ... authors contend that simply living in a major urban ... its way into your lungs when you breathe, increasing ...
... exercise cut the risk of diabetes by over half. ... be at increased risk of developing diabetes.// Given that ... very useful if there was some way of helping ... for the Diabetes Prevention Programme in the US have ...
Cached Medicine News:Health News:Comprehension of taste receptor, 2
... is a comprehensive IT solution that ... admission to follow-up. This scalable solution ... diagnostic tools from syngo Dynamics with ... longitudinal clinical repository that becomes a ...
... introduces the AXIOM Artis dBC Magnetic ... magnetic navigation system equipped with digital ... which is uniquely capable of improving ... procedures to facilitate increased efficiency and ...
The AXIOM Artis TC is ideal for applications above and beyond standard cardioangiography, and features:, Single plane C-Arm, ceiling-mounted, Full-size CCD camera, ...
The ACUSON Sequoia C512 system elevates imaging and Doppler performance through new, high-density acoustic sampling, precise control of the transmitted acoustic waveform, and new transducer technolog...
Medicine Products: