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Retigabine Significantly Reduces the Number of Seizures in Adults With Inadequately Controlled Partial-Onset Epilepsy
Date:12/6/2008

d by the disturbance. Primary generalized seizures involve the entire brain from the outset, while partial-onset seizures begin in a focal area of the cerebral cortex. In most cases, however, the cause of epilepsy is unknown.

Epilepsy affects more than 50 million people worldwide, including 3 million Americans. Approximately 30 percent of epilepsy patients are not adequately controlled with currently prescribed AEDs.

About GlaxoSmithKline

One of the world's leading research-based pharmaceutical and healthcare companies, GSK is committed to improving the quality of human life by enabling people to do more, feel better and live longer. For further information please visit http://www.gsk.com.

About Valeant

Valeant Pharmaceuticals International is a multinational specialty pharmaceutical company that develops, manufactures and markets a broad range of pharmaceutical products primarily in the areas of neurology and dermatology. More information about Valeant can be found at http://www.valeant.com.

     Inquiries:

     GSK US Media inquiries:                Robin Gaitens     (919) 483 2839
                                            Holly Russell     (919) 483 2839

     GSK US Analyst/ Investor inquiries:    Tom Curry         (215) 751 5419

     Valeant Media and Investor inquiries:  Laurie W. Little  (949) 461 6002

GSK cautionary statement regarding forward-looking statements

Under the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995, GSK cautions investors that any forward-looking statements or projections made by GSK, including those made in this announcement, are subject to risks and uncertainties that may cause actual results to differ materially from those projected. Factors that may affect GSK'
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SOURCE GlaxoSmithKline; Valeant Pharmaceuticals International
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