Navigation Links
Resveratrol Longevity Science Makes Dramatic U-Turn, But Resveratrol Supplements Remain Unchanged
Date:9/10/2008

Mega-dose Resveratrol, Sirtuin1 gene Target Discredited; Lower Dose, Array

of Small Molecules (Longevinex(R)) Exert Greater Effect

SAN DIMAS, Calif., Sept. 10 /PRNewswire/ -- While the red wine molecule resveratrol (rez-vair-ah-trawl) has recently attracted scientific and public attention as a longevity molecule that allegedly mimics the effects of a calorie-restricted diet, the science surrounding this molecule has taken a dramatic turn in recent months, according to Bill Sardi, spokesperson for Longevinex(R) (long-jev-in-ex), a major brand resveratrol supplement.

(Photo: http://www.newscom.com/cgi-bin/prnh/20080422/LATU004)

Published research studies now show:

-- Mice fed high-dose resveratrol did not live as long as mice fed a plain standard calorie diet. Animals on the lower dose (360 milligram human equivalent) lived longer than those on the higher dose (1565 mg) of resveratrol. [Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span. Cell Metabolism 2008 Aug;8(2):157-68]

-- The Sirtuin1 gene, once called the "holy grail" of longevity and believed to be the gene target of calorie restriction, has not been found to be universally activated by a limited calorie diet. A calorie-restricted diet results in more Sirtuin1 gene-derived proteins by exerting stabilization effects, not by activation of the gene. This new finding throws a scientific cloud over the use of Sirtuin1 gene activation tests as a measure of resveratrol activity. [Tissue-specific regulation of SIRT1 by calorie restriction. Genes Dev. 2008 Jul 1; 22(13):1753-7; Regulation of SIRT1 protein levels by nutrient availability. FEBS Letters. 2008 Jul 9; 582(16):2417-23]

-- While researchers once advised consumers to wait for stronger synthetic molecules that can stimulate the Sirtuin1 gene by 1
'/>"/>

SOURCE Resveratrol Partners, LLC
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Video: Resveratrol-based Nutriceutical (Longevinex(R)) Induces Favorable Changes on Gene Expression in Mouse Heart At Doses 17-320 Times Lower Than Prior Studies
2. Epiphany Biosciences to Continue Phase 2 Shingles Study After Interim Analysis; Plans Follow-On Clinical Trial Studying Post-Herpetic Neuralgia (PHN)
3. Ardea Biosciences to Present Data on Lead MEK Inhibitor, RDEA119, at American College of Gastroenterology Annual Scientific Meeting
4. Sangamo BioSciences Initiates Phase 2 Clinical Trial of Treatment for Amyotrophic Lateral Sclerosis (ALS)
5. Neurocrine Biosciences Announces Successful Elagolix PETAL Study in Endometriosis
6. Human Genome Sciences Reports Initial Results of Randomized Phase 2 Trial of HGS-ETR1 in Combination With Bortezomib in Advanced Multiple Myeloma
7. Regado Biosciences Reports Clinical Results for REG1 Anticoagulation System at European Society of Cardiology Congress 2008
8. Stem Cell Sciences Announces the Creation of the Worlds First Authentic Rat Embryonic Stem Cells from its Exclusively Licensed Technology
9. Neurosciences Institute Discovers Drug Extends Stroke Treatment Time to 24 Hours, Repairs Brain Tissue
10. Human Genome Sciences Completes Enrollment in Second Phase 3 LymphoStat-B(R) Trial
11. Human Genome Sciences Completes Enrollment in Randomized Phase 2 Trial of HGS-ETR1 in Non-Small Cell Lung Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)...  Valeant Pharmaceuticals International, Inc. (NYSE: VRX ... the sale to Galderma of all rights to Restylane, ... Valeant for $1.4 billion in cash, pursuant to the ... its acquisition of Galderma. "We are ... a company that is firmly committed to the aesthetic ...
(Date:7/10/2014)... July 10, 2014   LabStyle Innovations Corp ... today announced the appointment of Professor Richard ... its Board of Directors. Prof. Stone ... experience to LabStyle as an entrepreneur, venture capitalist ... corporate governance expert. He currently serves on the ...
(Date:1/15/2014)... , Jan. 15, 2014 Sono-Tek Corporation (OTC BB: SOTK) ... November 30, 2013, compared to sales of $2,202,000 for the ... again, this quarter has also shown growth over the preceding ... quarter of this fiscal year. Markets that experienced sales increases ...
Breaking Medicine Technology:LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 3LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 4Sono-Tek Announces Third Quarter Results 2Sono-Tek Announces Third Quarter Results 3Sono-Tek Announces Third Quarter Results 4
(Date:7/13/2014)... type-1 diabetes could improve patient care worldwide and ... the device,s inventors at the Stanford University School ... be published online July 13 in Nature ... type-1 diabetes outside hospital settings. The handheld microchips ... mellitus, which are both characterized by high blood-sugar ...
(Date:7/13/2014)... American water storage systems market is estimated to grow from ... a CAGR of 21.0%, from 2013 to 2018. The water ... North America. The U.S. is experiencing high growth on account ... collection, and the increased spending on modernization and upgradation of ... in Canada, and is rising at a rapid pace in ...
(Date:7/13/2014)... 13, 2014 Fuel additives are chemicals, ... diesel, jet fuel, kerosene, and so on, in order ... for reducing the corrosion effects caused by fuels and ... to any fuel, provide economies of scale in the ... the overall cost of the fuel products. , The ...
(Date:7/13/2014)... HealthDay Reporter FRIDAY, July 11, ... for people with diabetes is being developed to measure sugar ... report. Scientists at Brown University in Providence, R.I., created ... uses light, metal and a special enzyme that changes color ... have to prick their fingers to draw blood to check ...
(Date:7/13/2014)... (PRWEB) July 13, 2014 Recently, ... retailer, has unveiled its new range of gorgeous ... current market, the demand for elegant Quinceanera outfits ... more beautiful items. All the company’s newly released ... trends. They are all elegant and vivid. ...
Breaking Medicine News(10 mins):Health News:Stanford researchers invent nanotech microchip to diagnose type-1 diabetes 2Health News:Stanford researchers invent nanotech microchip to diagnose type-1 diabetes 3Health News:Stanford researchers invent nanotech microchip to diagnose type-1 diabetes 4Health News:North American Water Storage Systems Market is Expected to Reach $5,450 million by 2018 - New Report by MicroMarket Monitor 2Health News:North American Water Storage Systems Market is Expected to Reach $5,450 million by 2018 - New Report by MicroMarket Monitor 3Health News:North America Fuel Additives Market is Expected to Reach $8,100 Million by 2017 - New Report by MicroMarket Monitor 2Health News:North America Fuel Additives Market is Expected to Reach $8,100 Million by 2017 - New Report by MicroMarket Monitor 3Health News:North America Fuel Additives Market is Expected to Reach $8,100 Million by 2017 - New Report by MicroMarket Monitor 4Health News:Saliva Test Might Someday Replace Needle Prick for Diabetics 2Health News:Saliva Test Might Someday Replace Needle Prick for Diabetics 3Health News:2014QuinceaneraDresses.com Releases Its New Quinceanera Dresses 2
... presented innovative, early-stage research at the 16th Annual ... AUA Foundation and the Society for Basic Urologic ... Foundation hosted the forum for young investigators to ... sexual medicine. These investigators represent the future ...
... Clinical Team Conference on October 23,2008, ALEXANDRIA, ... to improving America,s future. A strong advocate for,children ... vocal advocate and,tireless worker on behalf of important ... Mrs. Edwards will be the opening speaker at,the ...
... men with enlarged prostates, daily Cialis showed benefit without ... -- A daily dose of the erectile dysfunction drug ... men with signs of enlarged prostates, according to a ... age 50 and older have lower urinary tract symptoms, ...
... saves hospital money, enables more wide-spread ... authentication for network access, DALLAS, ... Medical Center already was,leveraging two-factor authentication via hardware tokens in ... The,solution, however, was cost-prohibitive to deploy to a wider audience ...
... ... Practitioners, NEWPORT BEACH, Calif., ... a Managed Compliance Services,Program (MCSP) for small healthcare practitioners -- the ... Program is tailored to meet the HIPAA compliance,requirements of small healthcare ...
... reach 210,000 cups sold by Labor Day ... 2008, First-of-its-kind virtual lemonade stand ... ... the,fight to eliminate pediatric cancer charges ahead. The world,s first,virtual lemonade stand, http://www.lemonadestandforlife.com ...
Cached Medicine News:Health News:New research on sexual function 2Health News:Elizabeth Edwards to be Opening Speaker at National Hospice Conference in Dallas 2Health News:ED Drug Relieves Lower Urinary Tract Symptoms 2Health News:Entrust IdentityGuard Enables Georgia-based Hospital Network to Deploy Strong Authentication for Remote Access 2Health News:Entrust IdentityGuard Enables Georgia-based Hospital Network to Deploy Strong Authentication for Remote Access 3Health News:Managed Compliance Services Program (MCSP) Introduced for Small Healthcare Practitioners 2Health News:Managed Compliance Services Program (MCSP) Introduced for Small Healthcare Practitioners 3Health News:Make an Impact on Pediatric Cancer Research Before Summer's End: Try Some Virtual Lemonade! 2Health News:Make an Impact on Pediatric Cancer Research Before Summer's End: Try Some Virtual Lemonade! 3
The Bair Hugger outpatient blanket makes it easy to give your patients the benefit of prewarming and enhance patient comfort during outpatient procedures....
Cocoon Disposable Patient Warming Blankets are specially designed to prevent hypothermia and maintain normothermia in your patients. The soft warm coloured material is strong and resists tearing and ...
2-ply material consisting of polyethylene film inner layer and non-woven outer layers....
The upper body blanket is typically used for abdominal or lower body procedures. The upper body blankets warms the upper torso and arms. A clear drape is included to cover and warm the intubated pati...
Medicine Products: