Navigation Links
Results of the Phase III Pivotal Study of VYVANSE(TM) (Lisdexamfetamine Dimesylate) for the Treatment of ADHD in Adults Presented at National Scientific Meeting of Psychiatrists
Date:5/8/2008

VYVANSE demonstrated significant improvement in ADHD symptoms in adults

WASHINGTON, May 8 /PRNewswire-FirstCall/ -- Shire plc (LSE: SHP, Nasdaq: SHPGY), the global specialty biopharmaceutical company, today presented the results of a phase III pivotal study in which VYVANSE demonstrated significant improvements in Attention Deficit Hyperactivity Disorder (ADHD) symptoms in adults and met all safety and efficacy endpoints.

"Adults with ADHD often find it challenging to focus and organize during the day. The disorder may impact many aspects of their lives from career to family and personal commitments," said Lenard A. Adler, M.D., lead researcher in this study and director of the Adult ADHD program at the NYU Langone Medical Center, associate professor of psychiatry, neurology and child and adolescent psychiatry at the New York University School of Medicine, as well as author of Scattered Minds: Help and Hope for Adults with ADHD (G. P. Putnam's Sons 2006). "This study demonstrated that VYVANSE significantly improved ADHD symptoms in adults, including inattention, such as the ability to focus, organize and complete tasks, which are essential during an adult day, as well as hyperactivity, such as restlessness, and impulsivity."

This double-blind, placebo-controlled, four-week, forced-dose study in 414 adults aged 18 to 55 years showed that treatment with VYVANSE at all doses studied (30 mg, 50 mg, 70 mg) provided a significant reduction in ADHD Rating Scale (ADHD-RS-IV) scores within one week that were observed throughout the full treatment period. At endpoint, VYVANSE demonstrated a significant improvement in ADHD symptoms, based on a 43 percent reduction in ADHD-RS scores. This is the largest placebo-controlled stimulant trial of ADHD in adults conducted to date.

Additional Study Findings

Investigators also measured the efficacy of VYVANSE with the Clinical Global Impressions-Improvement (CGI-I) scale and found that the percent
'/>"/>

SOURCE Shire plc
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
2. Lexicon to Present Research Results at American Chemical Society Meeting Regarding Target of LX1031 Drug Candidate
3. Positive Kuvan(TM) Pivotal Phase 3 Trial Results Published in The Lancet
4. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
5. Tapestry Reports Second Quarter 2007 Results
6. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
7. Emisphere Technologies, Inc. Announces 2007 Second Quarter Financial Results
8. Amicus Therapeutics Announces Second Quarter 2007 Financial Results
9. Genta Incorporated Announces Second Quarter 2007 Financial Results and Corporate Highlights
10. Vical Reports Second Quarter 2007 Financial Results, Allowance of Pandemic Influenza IND and Other Advances in Product Development Programs
11. MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... OAKS, Calif. , Jan. 15, 2014 /PRNewswire/ ... and Amgen (NASDAQ: AMGN ) announced ... to jointly discover and validate new therapeutic targets ... (IBD), a chronic disorder that affects millions worldwide. ... in clinical medicine, IBD biology, human genetics, genomic ...
(Date:1/15/2014)... -- BreedIT Corp (OTC: BRDT), through its ... highly sophisticated agro-breeding solutions for plant breeders and researchers, ... board of directors appointed chemistry and pharmaceutical industry expert ... of the board. From 1975 to 2012, ... Ltd (NYSE: TEVA ) and its subsidiaries ...
(Date:1/15/2014)... 15, 2014 Tegra Medical is very pleased ... King as its new Chief Executive Officer.  Mark ... Officer, in which he has overseen the company,s four ... Mississippi , and Costa Rica.  Mr. King joined ... operations, sales, engineering and manufacturing experience in medical device ...
Breaking Medicine Technology:Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 3Tegra Medical Appoints New Chief Executive Officer 2Tegra Medical Appoints New Chief Executive Officer 3
... CINCINNATI, Sept. 27, 2011 To further reduce ... Ethicon Endo-Surgery, Inc. (EES), announced today the launch ... the industry,s first powered endocutter with enhanced system-wide ... worldwide, Powered ECHELON FLEX™ allows greater instrument stability ...
... 2011 Thousands of jobs in Ohio supported by ... policies – such as imposing new taxes in the ... policymakers. From research to technical work, manufacturing ... child care services, the biopharmaceutical sector supports a broad ...
Cached Medicine Technology:Ethicon Endo-Surgery Introduces First Powered Endocutter with Enhanced System-Wide Compression and Stability, Allowing Surgeons Greater Control in Laparoscopic Surgery 2Ethicon Endo-Surgery Introduces First Powered Endocutter with Enhanced System-Wide Compression and Stability, Allowing Surgeons Greater Control in Laparoscopic Surgery 3Ethicon Endo-Surgery Introduces First Powered Endocutter with Enhanced System-Wide Compression and Stability, Allowing Surgeons Greater Control in Laparoscopic Surgery 4Research Demonstrates Possible Ohio Job Losses from Sectors Supported by Biopharmaceutical Companies 2Research Demonstrates Possible Ohio Job Losses from Sectors Supported by Biopharmaceutical Companies 3
(Date:4/14/2014)... orphaned by HIV/AIDS in South Africa may provide insight ... behavior issues in other areas of the world, which ... that could lead to successful interventions. , A ... United Nations mentions that due to the HIV/AIDS pandemic, ... African, children are at an increased risk for mental ...
(Date:4/14/2014)... A new study shows that moderate to severe ... risk of stroke, cancer and death. , Results of ... to severe obstructive sleep apnea were four times more ... times more likely to have a stroke (HR = ... (HR = 3.4), and 2.5 times more likely to ...
(Date:4/14/2014)... Dallas study involving serious youth offenders, the answer to one ... seven years: "How long do you think you,ll live?", According ... offending over time., Author Dr. Alex Piquero said the study ... of them offend at very high rates and commit more ... much later in life offend much less., "In a lot ...
(Date:4/14/2014)... with symptoms increasing dramatically during some of the most important ... has found. , Depressive symptoms increased on average by 68 ... young men, who were around 25 years old when they ... their children. The results of the study were published April ... is the first to identify when young fathers are at ...
(Date:4/14/2014)... Lower weight babies and babies who aren,t breastfed ... risk of developing chronic inflammation and related health ... study. , "There were good reasons to hypothesize ... inflammation in adulthood," says Thomas McDade (Northwestern University), ... in the Child & Brain Development program. "It ...
Breaking Medicine News(10 mins):Health News:Researchers identify children with emotional behavior difficulties 2Health News:Researchers identify children with emotional behavior difficulties 3Health News:Study links severe sleep apnea to increased risk of stroke, cancer and death 2Health News:UT Dallas study: Youth who fail to envision future commit more crimes 2Health News:Young dads at high risk of depression, too 2Health News:Low birth weight, less breastfeeding create later health risks 2
... 29 Miami physician Roberto Rodriguez, 54, was sentenced today ... Medicare fraud scheme involving HIV infusion services, announced Assistant Attorney ... Attorney Jeffrey H. Sloman of the Southern District of Florida ... Health & Human Services (HHS). Rodriguez was also ordered to ...
... HealthFitness Corporation (NYSE Amex: FIT ... management solutions, announced today that the Company was added to ... on June 26, 2009, when Russell Investments reconstituted its comprehensive ... , About HealthFitness , HealthFitness is a leading ...
... BioMed Realty Trust, Inc. (NYSE: ... million loan with John Hancock Life Insurance Company, TIAA-CREF, and ... a single property - the Center for Life Science | ... that recently received Gold LEED(R) certification from the U.S. Green ...
... should be vaccinated, experts urge, , MONDAY, June 29 (HealthDay ... than a million Americans sickened by the new swine flu, ... , Several articles published online Monday by the New ... the new H1N1 flu strain attacks younger people and can ...
... Association of Health Underwriters Elects Rusty Rice, Louanne Trebing, ... , AUSTIN, Texas, June 29 The Texas ... chapter of the National Association of Health Underwriters, has ... year. TAHU members Rusty Rice, Louanne Trebing, Joanna Antongiovanni ...
... , ... of the few surgeons in the Maryland specially trained to perform the latest minimally invasive ... ... Hungerford, M.D. has joined Mercy Medical Center as the 135-year-old downtown hospital,s ...
Cached Medicine News:Health News:Miami Physician Sentenced to 97 Months in Prison for Role in $10 Million Medicare Fraud Scheme 2Health News:Miami Physician Sentenced to 97 Months in Prison for Role in $10 Million Medicare Fraud Scheme 3Health News:HealthFitness Added to the Russell Microcap Index 2Health News:BioMed Realty Trust Completes $350 Million Financing for Center for Life Science Boston 2Health News:BioMed Realty Trust Completes $350 Million Financing for Center for Life Science Boston 3Health News:BioMed Realty Trust Completes $350 Million Financing for Center for Life Science Boston 4Health News:Younger People Appear More at Risk From New Swine Flu 2Health News:Younger People Appear More at Risk From New Swine Flu 3Health News:Younger People Appear More at Risk From New Swine Flu 4Health News:TAHU Takes on New Leadership During Vital Time in Health Insurance Industry 2Health News:Orthopedic Surgeon Dr. Marc W. Hungerford, a Leading Expert in Field of Avascular Necrosis, Now at Baltimore's Mercy Medical Center 2Health News:Orthopedic Surgeon Dr. Marc W. Hungerford, a Leading Expert in Field of Avascular Necrosis, Now at Baltimore's Mercy Medical Center 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: