Navigation Links
Results of VYVANSE(TM) (lisdexamfetamine dimesylate) Pivotal Trial in Adult ADHD Presented at Major Scientific Meeting
Date:10/25/2007

All Doses of VYVANSE Studied Demonstrated Significant Efficacy Within One

Week of Daily Treatment

BOSTON, Oct. 25 /PRNewswire-FirstCall/ -- Shire plc (LSE: SHP, Nasdaq: SHPGY, TSX: SHQ), the global specialty biopharmaceutical company, today announced the results of a study which demonstrated that adults with Attention Deficit Hyperactivity Disorder (ADHD) experienced significant improvements in ADHD symptom control within one week of treatment with once- daily VYVANSE(TM) (lisdexamfetamine dimesylate), the first prodrug stimulant. Findings from this phase III pivotal trial were presented today at a national psychiatric meeting in Boston, Mass.

"Adults with ADHD may experience significant impairments in their ability to focus, and organize and complete tasks, which could affect their work, family life and personal relationships," said Lenard A. Adler, M.D., lead researcher in this study and director of the Adult ADHD Program at New York University School of Medicine and author of Scattered Minds: Help and Hope for Adults with ADHD. "The results of this study demonstrated that VYVANSE significantly improved the core symptoms of ADHD in adult study patients."

Results of Phase III Pivotal Trial

In this double-blind, placebo-controlled, four-week study with dose escalations in 414 adults aged 18 to 55 years, treatment with VYVANSE at all doses studied (30 mg, 50 mg, 70 mg) was significantly more effective than placebo and improvements were observed in the first week of the study.

All doses of VYVANSE showed significant improvements in the average change in ADHD Rating Scale (ADHD-RS-IV) scores, as measured from the study's start to end, the primary endpoint of this study. ADHD-RS-IV is a standardized, validated test for assessing symptoms of ADHD and for assessing their response to treatment. The scale, which contains 18 items, is based on the ADHD diagnostic criteria as defined in the Diagnostic and Statisti
'/>"/>

SOURCE Shire plc
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results
2. Diagnosing Diabetes: Immediate HbA1c Results Improve Glycemic Control
3. Cell Therapeutics, Inc. Management to Discuss Todays Announcement of Interim Pixantrone Study Results
4. Sygnis Pharma AG announces date for presentation of clinical results
5. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
6. Positive Aggrastat Results Featured in the Journal of the American College of Cardiology
7. Pixantrone Combination Therapy for First-line Treatment of Aggressive Non-Hodgkins Lymphoma Results in Reduction in Severe Toxicities Including Heart Damage When Compared to Doxorubicin-based Therapy
8. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
9. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
10. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
11. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... BUENA, N.J. , June 30, 2015  IGI ... Jersey based specialty generic pharmaceutical company, today ... application (ANDA) to the U.S. Food and Drug Administration ... of ANDA submissions now pending at the FDA to ... CEO of the Company, commented, "We believe our current ...
(Date:6/30/2015)... Millar, Inc. , a leader in catheter-based and wireless ... Craig Thummel , President/CEO and member of the ... the Company. The Company also announced its leadership succession ... Management team as his successors. The Board of Directors ... Sales and Marketing, as President, and also a member ...
(Date:6/30/2015)... June 30, 2015 A new analysis ... exposure to high-priced Hepatitis C medications could range ... percent of Californians infected with Hepatitis C receive treatment through ... of new Hepatitis C treatments on public programs, comes at ... price tags for drugs like Gilead Sciences, Harvoni and Sovaldi. ...
Breaking Medicine Technology:IGI Laboratories, Inc. Announces Fifth ANDA Submission Of 2015 2Millar, Inc. Announces Leadership Changes 2Millar, Inc. Announces Leadership Changes 3New Analysis Reveals High-Priced Hepatitis C Drugs Could Have Costly Impact on State 2New Analysis Reveals High-Priced Hepatitis C Drugs Could Have Costly Impact on State 3New Analysis Reveals High-Priced Hepatitis C Drugs Could Have Costly Impact on State 4
... Reportlinker.com announces that a new market research ... Commercial Insight: Antihormonal Cancer Therapies ... sales erosion http://www.reportlinker.com/p0255121/Commercial-Insight-Antihormonal-Cancer-Therapies---Leading-brands-strive-to-minimize-generic-sales-erosion.html ... are a class of drugs used predominantly ...
... Ind., Nov. 8, 2010 EXTENSION, INC . announced ... it will make available for general release to the healthcare ... existing offerings use Cisco IP devices and smartphones as end ... the smartphone devices will not only serve as communication end ...
Cached Medicine Technology:Commercial Insight: Antihormonal Cancer Therapies - Leading Brands Strive to Minimize Generic Sales Erosion 2Commercial Insight: Antihormonal Cancer Therapies - Leading Brands Strive to Minimize Generic Sales Erosion 3Commercial Insight: Antihormonal Cancer Therapies - Leading Brands Strive to Minimize Generic Sales Erosion 4Commercial Insight: Antihormonal Cancer Therapies - Leading Brands Strive to Minimize Generic Sales Erosion 5Commercial Insight: Antihormonal Cancer Therapies - Leading Brands Strive to Minimize Generic Sales Erosion 6Commercial Insight: Antihormonal Cancer Therapies - Leading Brands Strive to Minimize Generic Sales Erosion 7Commercial Insight: Antihormonal Cancer Therapies - Leading Brands Strive to Minimize Generic Sales Erosion 8Commercial Insight: Antihormonal Cancer Therapies - Leading Brands Strive to Minimize Generic Sales Erosion 9EXTENSION, INC. to Launch Apple iPhone Application for Use in Clinical Workflows 2EXTENSION, INC. to Launch Apple iPhone Application for Use in Clinical Workflows 3
(Date:7/1/2015)... ... July 01, 2015 , ... Who doesn’t want a ... in life with a healthy balance between work and life, and positive friendships and ... new book, Positive Health: Flourishing Lives, Wellbeing in Doctors. , With a focus on ...
(Date:7/1/2015)... ... ... Incentivizing the use of generic drugs has been an easy way for ... 90% off the prices for the brand-name products. But now that generics are experiencing ... of these high-cost generic drugs. The July issue of Atlantic Information Services, Inc.’s (AIS) ...
(Date:7/1/2015)... ... 2015 , ... The Recovery Workforce Summit: 2015 PRA Annual Conference , ... The Atlantic, as a keynote on June 2nd in Philadelphia, PA. Stossel led a ... story added power and reach to the essential message, while opening doors to wellness ...
(Date:7/1/2015)... , ... July 01, 2015 , ... ... to the global distribution and marketing of a number of nutritional and beauty ... it attended the 2015 ECRM Diet, Vitamin & Sports Nutrition conference in Tampa, ...
(Date:7/1/2015)... ... 01, 2015 , ... The Thule Atmos X4 offers protection with minimal bulk. ... lived up to Thule’s rigorous standards. Due to its Bi-ComponentArmor and ShockStop corners, it ... come to expect. , The Thule Atmos X4 has also been designed ...
Breaking Medicine News(10 mins):Health News:Medical Doctor Explains The Healthy Effects of a Positive Outlook in New Book 2Health News:Blues Execs Share Strategies for Managing Generic Drug Inflation in AIS Newsletter 2Health News:Blues Execs Share Strategies for Managing Generic Drug Inflation in AIS Newsletter 3Health News:Scott Stossel, Editor of The Atlantic, Addressed Mental Health Professionals on Reducing Prejudice and Discrimination 2Health News:Scott Stossel, Editor of The Atlantic, Addressed Mental Health Professionals on Reducing Prejudice and Discrimination 3Health News:Scott Stossel, Editor of The Atlantic, Addressed Mental Health Professionals on Reducing Prejudice and Discrimination 4Health News:Scott Stossel, Editor of The Atlantic, Addressed Mental Health Professionals on Reducing Prejudice and Discrimination 5Health News:NPI Executives Report Great Success at ECRM Conference 2
... unclear why it’s so, scientists at Johns Hopkins have linked ... tough//, protective casing that houses insects and worms to the ... ,A team of Hopkins sinus experts has found that the ... to 250 times more active in people with severe sinus ...
... say that there is nothing that matches gambling. Not even ... addict//. ,There has been an upsurge of gambling ... with gambling problems. According to some experts, this has led ... ,"It's related to other addictions, like alcoholism and tobacco addiction. ...
... may no longer be included in the specialist category, if ... ,A few radiologists who have had the opportunity ... them as part of the team. But the rest are ... physicians are unable to seek employment in breast clinics. And ...
... common man has seen a rapid increase in healthcare charges ... been affected not only by the rising cost of living// ... money-spinning business. ,The government in 2003 revised the ... had the benefit of ‘free’ hospital visits. In fact, they ...
... 10, sent a warning against dengue fever in the midst ... capital//. ,From this year’s January 1 to ... been reported, said the department. ,In order ... collaboration with the local officials of the affected areas, according ...
... and Drug Administration has charged the American Red Cross yet ... to the stipulation of safe blood collection techniques.// The Red ... the nation's requirement of blood, has been under the vigilance ... make the blood safe by enhancing the quality control system., ...
Cached Medicine News:Health News:Immune Response Linked to “Ghost” Parasites and Severely Congested Sinus 2Health News:Immune Response Linked to “Ghost” Parasites and Severely Congested Sinus 3Health News:Immune Response Linked to “Ghost” Parasites and Severely Congested Sinus 4Health News:Compulsive Gambling – a psychiatric disorde 2Health News:Escalating Healthcare charges in UAE 2Health News:Escalating Healthcare charges in UAE 3Health News:‘Search and Destroy’ operation against dengue mosquitoes in Philippin 2
... an OraSure HIV-1 Oral Specimen Collection Device is ... for HIV-1 antibodies. Testing with the OraSure HIV-1 ... needles and has been shown to be more ... specially treated cotton fiber pad attached to a ...
... benefits of TiMAX material have been applied to ... strength and an ultra-low profile combine to provide ... lower extremity. , ,This complete set of periarticular ... , Fibula Composite Plate , ...
The DePuy ACE Titanium Active Compression Plate offers ingenuity in the art of fracture management....
Corneal Marking Pen - Sterile. 10 pieces/box...
Medicine Products: