Navigation Links
Results of VYVANSE(TM) (lisdexamfetamine dimesylate) Pivotal Trial in Adult ADHD Presented at Major Scientific Meeting
Date:10/25/2007

All Doses of VYVANSE Studied Demonstrated Significant Efficacy Within One

Week of Daily Treatment

BOSTON, Oct. 25 /PRNewswire-FirstCall/ -- Shire plc (LSE: SHP, Nasdaq: SHPGY, TSX: SHQ), the global specialty biopharmaceutical company, today announced the results of a study which demonstrated that adults with Attention Deficit Hyperactivity Disorder (ADHD) experienced significant improvements in ADHD symptom control within one week of treatment with once- daily VYVANSE(TM) (lisdexamfetamine dimesylate), the first prodrug stimulant. Findings from this phase III pivotal trial were presented today at a national psychiatric meeting in Boston, Mass.

"Adults with ADHD may experience significant impairments in their ability to focus, and organize and complete tasks, which could affect their work, family life and personal relationships," said Lenard A. Adler, M.D., lead researcher in this study and director of the Adult ADHD Program at New York University School of Medicine and author of Scattered Minds: Help and Hope for Adults with ADHD. "The results of this study demonstrated that VYVANSE significantly improved the core symptoms of ADHD in adult study patients."

Results of Phase III Pivotal Trial

In this double-blind, placebo-controlled, four-week study with dose escalations in 414 adults aged 18 to 55 years, treatment with VYVANSE at all doses studied (30 mg, 50 mg, 70 mg) was significantly more effective than placebo and improvements were observed in the first week of the study.

All doses of VYVANSE showed significant improvements in the average change in ADHD Rating Scale (ADHD-RS-IV) scores, as measured from the study's start to end, the primary endpoint of this study. ADHD-RS-IV is a standardized, validated test for assessing symptoms of ADHD and for assessing their response to treatment. The scale, which contains 18 items, is based on the ADHD diagnostic criteria as defined in the Diagnostic and Statisti
'/>"/>

SOURCE Shire plc
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results
2. Diagnosing Diabetes: Immediate HbA1c Results Improve Glycemic Control
3. Cell Therapeutics, Inc. Management to Discuss Todays Announcement of Interim Pixantrone Study Results
4. Sygnis Pharma AG announces date for presentation of clinical results
5. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
6. Positive Aggrastat Results Featured in the Journal of the American College of Cardiology
7. Pixantrone Combination Therapy for First-line Treatment of Aggressive Non-Hodgkins Lymphoma Results in Reduction in Severe Toxicities Including Heart Damage When Compared to Doxorubicin-based Therapy
8. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
9. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
10. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
11. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... Calif. , Aug. 28, 2015  CytomX Therapeutics, ... treatment of cancer, today announced the filing of a ... and Exchange Commission (SEC) relating to a proposed initial ... shares to be offered and the price range for ... to list its common stock under the symbol "CTMX" ...
(Date:8/28/2015)... DUBLIN , Aug. 28, 2015 ... announced the addition of the "Investigation Report on ... Developed by Roche under the trade name ... in the world. In Feb.26, 2010, it was approved ... injections available in China all ...
(Date:8/28/2015)... 2015  Today, in final recognition of the Centers ... Week, 1-800 Contacts is sharing how to keep lens ... wearers who do not properly care for their lens ... Most contact lens wearers understand the ... lens case is sometimes overlooked.  When proper steps to ...
Breaking Medicine Technology:CytomX Files Registration Statement for Proposed Initial Public Offering 2Investigation Report on China's Bevacizumab Market 2015-2019 21-800 Contacts Shares Tips on How to Clean Lens Cases 2
... 11, 2012 PLC Systems Inc. (OTCBB: PLCSF), a ... it will demonstrate its innovative product, RenalGuard ® , ... of Percutaneous Cardiovascular Interventions (EAPCI).  More than 11,000 clinicians ... to attend this event in Paris, France from May ...
... SOUTH BEND, Ind., May 11, 2012  Heraeus Kulzer, ... announced that it has launched a new light ... Venus Pearl is indicated for adhesively bonded, tooth-colored ... to its remarkably soft consistency, this new universal ...
Cached Medicine Technology:PLC to Demonstrate RenalGuard® at EuroPCR 2012 2PLC to Demonstrate RenalGuard® at EuroPCR 2012 3Heraeus Launches Remarkably Smooth Venus® Pearl Composite 2Heraeus Launches Remarkably Smooth Venus® Pearl Composite 3
(Date:8/29/2015)... ... August 29, 2015 , ... ProDrop Particles includes over ... preset contains 15 seconds of unique footage that users can shrink and stretch in ... attract and more. Users can customize color, brightness, scale, speed, range, and flare attributes ...
(Date:8/28/2015)... ... August 29, 2015 , ... Rio Salado College joined nine ... experience as part of the EDUCAUSE - Next Generation Learning Challenges 2015 Breakthrough Models ... the third Breakthrough Models Incubator hosted by EDUCAUSE and NGLC, which is ...
(Date:8/28/2015)... ... ... An article published August 19th by the LA Times documented ... open a pizzeria in Westchester. Mr. LaRocco was aware from opening prior pizza parlors ... current process, having already gone on for over a year, is taking much longer ...
(Date:8/28/2015)... ... ... The 6th Annual Survivor in the City, Chicago silent auction and cocktail ... its cadre of widespread support—an official letter of support and gratitude from the Mayor ... and the University of Illinois at Chicago’s Department of Neurosurgery, the Brain Aneurysm Foundation ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... for documenting and diagramming network and data center assets and audio-video devices, recently ... Model, Cisco Nexus 5000 Series, HP ProLiant Gen9, EMC VNX Series , Super ...
Breaking Medicine News(10 mins):Health News:FCPX Effects Developer, Pixel Film Studios, Releases ProDrop Particles. 2Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 2Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 3Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 4Health News:Article on Building Approval Process for LA Business Highlights the Need for a Bridge Between Businesses and City Officials, says Fire Protection Group Inc. 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 3Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 2Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 3
... FRIDAY, Sept. 17 (HealthDay News) -- As flu season ... organizations are highlighting the need for pregnant women to ... "Based on expert medical opinion, we urge all pregnant ... get their influenza immunization because the flu poses a ...
... FRIDAY, Sept. 17 (HealthDay News) -- Most parents these days ... lock up household cleaners and keep chemicals and pesticides well ... believe the most prevalent poisoning threat in a person,s household ... in the medicine cabinet. Two of every three pediatric ...
... of Liverpool could lead to faster and more accurate diagnoses of ... for the study: research indicates that paracetamol can place temporary stress ... a normal dose (4g per day) but the liver returns to ... drug are a major cause of liver failure in both the ...
... German . The increase of artificial night lighting ... is no doubt that chemical and noise pollution can have ... subtle consequences of light pollution on wild populations of animals ... Institute for Ornithology have now shown that permanent night lighting ...
... By Madonna Behen HealthDay Reporter , THURSDAY, ... people are much better at turning their thoughts inward and ... may come down partly to differences in brain structure. ... of Science , researchers report that people who ...
... Reporter , THURSDAY, Sept. 16 (HealthDay News) -- When it ... known as cryotherapy -- works better than applying salicylic acid, ... one treatment cured more than half of cases, however, and ... say. The new finding is a bit of an ...
Cached Medicine News:Health News:Pregnant Women Urged to Get Flu Shot 2Health News:Pregnant Women Urged to Get Flu Shot 3Health News:Medicines Pose Greater Threat to Kids Than Chemicals 2Health News:Medicines Pose Greater Threat to Kids Than Chemicals 3Health News:Medicines Pose Greater Threat to Kids Than Chemicals 4Health News:Research could improve detection of liver damage 2Health News:Light is the friend of lovers 2Health News:Light is the friend of lovers 3Health News:Feeling Introspective? Your Brain Structure May Be Key 2Health News:Feeling Introspective? Your Brain Structure May Be Key 3Health News:For Common Warts, Freezing Therapy Works Best: Study 2Health News:For Common Warts, Freezing Therapy Works Best: Study 3
... offers special drawers for just about everything imaginable ... microscopy laboratory. Each box is designed for long ... the advantages of wood over metal systems is ... as a subtle kind of desiccator and insulator, ...
It's a slide cabinet system, store up to 54,000 slides in only 2 square feet of space. Ideal for use in Pathology, Cytology, Hematology, Histology, Dermatology, Research, Education....
Unit System Slide Cabinet is constructed from hardwood for long lasting....
Shandon Wooden Slide File Storage Box...
Medicine Products: