Navigation Links
Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF Presented at American Thoracic Society (ATS)
Date:5/19/2009

both studies and were considered exploratory.

Enrollment of both trials was completed in less than 13 months following randomization of the first patient into the program in late April 2006. Ninety-seven percent (97%) of all patients in the two CAPACITY studies who were living and had not received a lung transplant, completed their Week 72 study visit.

Regarding RECAP, 603 patients from CAPACITY have been enrolled in this on-going open-label roll-over study from CAPACITY to evaluate the long-term safety of pirfenidone in patients with IPF.

About Pirfenidone

Preclinical and in-vitro evidence had shown that pirfenidone inhibits collagen synthesis, down-regulates profibrotic cytokines and decreases fibroblast proliferation. Prior to the current results, data were presented from one Phase 3 study and four Phase 2 clinical trials in more than 400 patients which suggested that pirfenidone may positively affect lung function and disease progression in patients with IPF. In those clinical studies, pirfenidone was generally safe and well tolerated with the most frequent side effects reported being photosensitivity rash and gastrointestinal symptoms. In October of 2008, pirfenidone was approved for use in IPF patients in Japan and is marketed as Pirespa(R) by Shionogi in that country.

About IPF

Idiopathic pulmonary fibrosis (IPF) is a disabling and ultimately fatal disease that affects approximately 200,000 people in the United States and Europe combined, with approximately 30,000 new cases reported per year in each of the United States and Europe.

IPF is characterized by inflammation and scarring (fibrosis) in the lungs, hindering the ability to process oxygen and causing shortness of breath (dyspnea) and cough and is a progressive disease, meaning that over time, lung scarring and symptoms increase in severity. The median survival time from diagnos
'/>"/>

SOURCE InterMune, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12

Related medicine technology :

1. Shire Announces Study Results of the Effects of INTUNIV(TM) (Guanfacine) Extended Release on Secondary Measures in Children with ADHD and Oppositional Symptoms
2. Optimer Pharmaceuticals Presents Results From Fidaxomicin Phase 3 Study for the Treatment of Clostridium difficile Infection
3. BioVex to Report Phase I/II Clinical Trial Results for the Front Line Treatment of Head and Neck Cancer With OncoVEX GM-CSF at the 2009 American Society of Clinical Oncology Meeting
4. TYRX Presents Early Clinical Results from AIGISRX(TM) Antibacterial Envelope Retrospective Registry
5. Metabolic Solutions Development Company Announces Preliminary Results from Phase IIa Clinical Trial
6. AlphaVax Announces Promising Results in Melanoma Studies
7. Ongoing Landmark ROADMAP Study Demonstrates Significant Improvement in Blood Pressure Control at One Year, According to Blinded Results
8. BioCryst Provides Peramivir Update and Reports First Quarter 2009 Financial Results
9. Bionovo Announces First Quarter 2009 Highlights and Financial Results
10. Alexza Reports 2009 First Quarter Financial Results and Updates Clinical Pipeline Status
11. ADVENTRX Announces Results From ANX-514 Bioequivalence Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... 29, 2014  EnteroMedics Inc. (NASDAQ: ETRM ... to treat obesity, metabolic diseases and other gastrointestinal disorders, ... on Thursday, August 7, 2014 at 11:00 AM Eastern ... ended June 30, 2014 and to provide a business ... second quarter conference call may be accessed by dialing ...
(Date:7/29/2014)... -- Synthetic Biologics, Inc. (NYSE MKT: SYN), a developer of ... that cause serious infections and diseases, announced today that ... Company,s stock, the NYSE MKT (the "Exchange") has contacted ... Company stated that its policy is not to comment ... Inc. Synthetic Biologics, Inc. (NYSE MKT: SYN) ...
(Date:7/29/2014)... -- ISPE—the International Society for Pharmaceutical Engineering announced ... as President and CEO, succeeding Nancy Berg ... last fall.  Mr. Bournas takes the helm at ... industry as well as significant international experience.  He ... the expansion of its global initiatives and business ...
Breaking Medicine Technology:EnteroMedics to Host Second Quarter 2014 Financial Results and Business Update Conference Call 2EnteroMedics to Host Second Quarter 2014 Financial Results and Business Update Conference Call 3Synthetic Biologics, Inc. States that Its Policy is Not to Comment on Unusual Market Activity 2ISPE Hires Healthcare Association Exec as CEO 2ISPE Hires Healthcare Association Exec as CEO 3
(Date:7/29/2014)... July 29, 2014 Winter is here ... Thursday afternoon in Sydney’s central business district. That is, ... Maori costume transformed the otherwise ordinary day into a ... singers are ardent advocates of The Truth About Drugs, ... of Scientology . They woke up the city with ...
(Date:7/29/2014)... Daily Gossip writes in its Fibroids Miracle review that ... teach users how to permanently eliminate uterine fibroids. The system ... over the world. , They have been able to ... quickly as 12 hours. This means that pain and other ... The Fibroids Miracle review also indicates that the method was ...
(Date:7/29/2014)... 29, 2014 Daily Gossip indicates in its ... tips to gain beautiful and clear skin in just 30 ... see these positive results even sooner than that. The new ... who used this step by step program, too. , ... for years. Mike battled this condition for a decade and ...
(Date:7/29/2014)... procedures using stem cells are running far ahead of ... a review in the August issue of ... journal of the American Society of Plastic Surgeons ... the marketplace is saturated with unsubstantiated and sometimes fraudulent ... Michael T. Longaker of Stanford University Medical Center and ...
(Date:7/29/2014)... 2014 As the Ebola outbreak in Liberia ... to both purchase critical emergency supplies locally, as well as ... These supplies will contain materials used to control the spread ... areas of the country. , With a large programmatic ... to the Ebola outbreak in the region. The current epidemic ...
Breaking Medicine News(10 mins):Health News:Sydney Business District “Rocked” by The Truth About Drugs 2Health News:Amanda Leto’s Fibroids Miracle Review Reveals Clinically Proven Uterine Fibroids Cure System 2Health News:Acne No More Review Reveals Most Effective Acne Cure Program 2Health News:Beware of claims about cosmetic stem cells procedures, says review in Plastic and Reconstructive Surgery 2Health News:PCI Responds to Ebola Outbreak in Liberia with Supplies, Awareness Campaigns 2Health News:PCI Responds to Ebola Outbreak in Liberia with Supplies, Awareness Campaigns 3
... Smart for Life(TM), the all-natural weight management program, opened in ... The Raimondo family began their weight-loss journey on the Smart ... of 235 lbs. for 6 family members. As friends and ... Raimondo envisioned an exciting business opportunity. , "Smart ...
... Haemonetics Corporation (NYSE: HAE ) will announce its ... release and 10:00 am (EST) webcast. , Webcast Link: ... from November 2, 2009 after 1:00 pm to November 9, ... Julie Fallon, Tel. (781) 356-9517, ...
... (Nasdaq: JMBA ) - As a part of their ... will be bringing some unexpected feel good boosts into people,s ... and Golden State visitors to free cable car rides this ... Jambassador, will bring unexpected cheer to riders as he makes ...
... ... ... has recently been promoted to Senior Vice President of Operations at Jackson & Coker ... , , , , ,"This position has been vacant for a while and ...
... ... announced the launch of their "Tats for Tatas" fundraising campaign that will ... In the company,s concerted efforts to raise awareness and funds for ... In addition, the company will be donating 10% of all proceeds from ...
... ... book Knockout: Interviews with Doctors Who are Curing Cancer and How to Prevent Getting It ... ... eight medical doctors featured in Suzanne Somers’ new book Knockout: Interviews with Doctors Who are ...
Cached Medicine News:Health News:Smart for Life(TM) Center Opens in Ottawa 2Health News:Surprise! Jamba Juice Treats Lucky San Francisco Cable Car Passengers to Free Rides on Saturday, October 17 2Health News:Surprise! Jamba Juice Treats Lucky San Francisco Cable Car Passengers to Free Rides on Saturday, October 17 3Health News:Jackson & Coker Promotes Tony Rico to Senior VP of Operations 2Health News:Atomic Tattoos Announces "Tats for Tatas" October Fundraising Event to Benefit Local Breast Cancer Research 2Health News:Suzanne Somers Highlights Dr. Stephen Sinatra in Chapter for New Cancer Book 2
... The MicroTouch LP (low profile) is ... with a fixed fluoroscopy/x-ray gantry. The MicroTouch ... opposite the gantry and allows the user ... fluoroscopy ,and x-ray without loss of ...
Floor stand stabilizer system...
The robust, easy to maneuver floor-mounted stepper/stabilizer, offers strength and stability that has made this unit one of the most widely accepted floor fixation devices in the industry....
... of a welded titanium capsule containing either ... beads. The capsule body also contains ... x-ray markers to identify the source location ... non-sterile when shipped and must be sterilized ...
Medicine Products: