Navigation Links
Results of NeuroThera Effectiveness and Safety Trial - 2 (NEST-2) Presented at International Stroke Conference 2009
Date:2/20/2009

Encouraging Safety and Efficacy Results Support Follow-on NEST-3 Trial

CARLSBAD, Calif., Feb. 20 /PRNewswire/ -- In a clinical trial sponsored by PhotoThera, Inc., transcranial laser therapy (TLT) for acute ischemic stroke within 24 hours of stroke onset demonstrated improved outcomes for patients, but did not meet statistical significance for efficacy. A post-hoc analysis in patients who had moderate to moderately severe strokes revealed a statistically significant treatment effect. These encouraging results support a follow-on phase III trial, NEST-3.

The results of the NEST-2 study (NeuroThera(R) Effectiveness and Safety Trial - 2) were presented at the American Heart Association's International Stroke Conference in San Diego, CA by Justin Zivin, M.D., Ph.D., Professor of Neurosciences at the University of California San Diego and Principal Investigator for the NEST-2 study. The results were also published online today in Stroke: Journal of the American Heart Association.

NEST-2 was a double-blind, sham-controlled (placebo) trial which enrolled 660 patients. Patients were eligible for inclusion in the study if they were 40-90 years of age, had moderate to severe strokes, and had not received tissue plasminogen activator (tPA). Initiation of treatment had to occur within 24 hours after stroke onset.

In NEST-2, TLT achieved a favorable outcome in 36.3% of patients compared to only 30.9% of patients in the sham group (p-value 0.094). The primary efficacy endpoint was a favorable 90-day score of 0-2 using the modified Rankin Scale (mRS). Mortality rates and serious adverse events (SAEs) did not differ between groups, providing further evidence of the safety of TLT.

A post-hoc analysis of 434 patients who suffered moderate to moderately severe strokes showed a favorable outcome in 51.6% of patients in the TLT group compared to 41.9% of patients in the
'/>"/>

SOURCE PhotoThera, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
2. Lexicon to Present Research Results at American Chemical Society Meeting Regarding Target of LX1031 Drug Candidate
3. Positive Kuvan(TM) Pivotal Phase 3 Trial Results Published in The Lancet
4. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
5. Tapestry Reports Second Quarter 2007 Results
6. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
7. Emisphere Technologies, Inc. Announces 2007 Second Quarter Financial Results
8. Amicus Therapeutics Announces Second Quarter 2007 Financial Results
9. Genta Incorporated Announces Second Quarter 2007 Financial Results and Corporate Highlights
10. Vical Reports Second Quarter 2007 Financial Results, Allowance of Pandemic Influenza IND and Other Advances in Product Development Programs
11. MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... NEW YORK and LONDON ... in global orthopedic industry are expected to grow at ... consumption in terms of value and volume. Hip, knee ... the developed world while in emerging economies they have ... failure rates are challenging the use of composites. Non-metallic ...
(Date:12/24/2014)... KENNEWICK, Wash. , Dec. 23, 2014 /PRNewswire/ ... stage development company engaged primarily in the development ... and therapeutic applications, today announced that it has ... the Food and Drug Administration ("FDA") for marketing ... to Section 513(f)(2) of the U.S. Food, Drug ...
(Date:12/24/2014)... LEXINGTON, Mass. , Dec. 23, 2014 /PRNewswire/ ... GEVA ), a biopharmaceutical company developing therapeutic products ... European Medicines Agency (EMA) of the Marketing Authorization ... The EMA recently granted the company,s request for ... the EMA,s regulatory review time.   ...
Breaking Medicine Technology:Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 2Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 3Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 2Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 3
... by Nobel laureate Paul Greengard, Medical Director of The Michael ... Dr. Jennifer L. Warner-Schmidt in New York and colleagues in ... the brain protein called p11 could lead pharmaceutical companies to ... rather than the weeks or even months required by current ...
... 23 Since 1993, when the PLCO trial was started, ... anticipation, as have others. The initial report of the results ... trial -- published last week in the New England Journal ... , * The studies offer conflicting evidence about the possibility ...
Cached Medicine Technology:Key Protein May Lead to Faster Acting Anti-Depression Drugs 2A Joint Statement From America's Prostate Cancer Advocacy, Education, and Support Organizations 2A Joint Statement From America's Prostate Cancer Advocacy, Education, and Support Organizations 3
(Date:12/25/2014)... Carolina (PRWEB) December 25, 2014 ... Carolina Retirement Community, recently showed their generous spirit ... of the Catawba County Parenting Network- Grandparents Raising ... 10 children gathered around the largest Christmas tree ... open presents purchased by residents of the Abernethy ...
(Date:12/24/2014)... AlignLife of Wauwatosa loves helping those in the ... holiday season, AlignLife looks forward to their annual toy drive. ... Mahalko-Leonhardt, owner of AlignLife. "It brings our patients as well ... able to give kids toys for Christmas who would be ... of our patients." , The 70 toys were donated to ...
(Date:12/24/2014)... (PRWEB) December 24, 2014 Connie Casad, ... and functional medicine advocate with 30 years of practice ... to evaluate the health benefits of dietary detoxification. The ... new participants following excellent results from test patients who ... asked to explain her interest in conducting the study, ...
(Date:12/24/2014)... 2014 New studies reveal that women under ... related depression (March 6, 2014, JAMA Otolaryngology*). And although many ... (about 50 percent according to recent polls) facing hearing loss ... a person feels and relates to the world. People who ... also made by way of:, , self-confidence ...
(Date:12/24/2014)... (PRWEB) December 25, 2014 Today, UWDress.com, the ... long sleeve wedding gowns, and launched a site-wide wedding gown ... long sleeve wedding gowns in a more unexpected way, the ... company are popular in the global market, and they are ... at UWDress.com are offered at discounted prices, up to 75% ...
Breaking Medicine News(10 mins):Health News:Retirement Community Residents Make Impact During Holiday Season 2Health News:AlignLife of Wauwatosa Brings Joy to Less Fortunate Families 2Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 2Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 3Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 2Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 3Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 4Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 5Health News:Recent Studys Underscore the Fact That One of the Best Gifts to Give This Holiday Season is a Hearing Test 6Health News:Buy Cheap Long Sleeve Wedding Gowns At UWDress.com 2
... April 27 Estill Medical Technologies, Inc., the industry ... announces the expansion of its Thermal Angel sales and ... mortality by quickly controlling core body temperature and infection ... administration. In emergency medicine, the golden hour refers to ...
... Members to Help Raise Obesity on the Nation,s Public ... health associations and obesity experts joined the S ... P revent (STOP) Obesity Alliance today as the organization ... grappling with the high costs of weight-related health conditions ...
... illnesses in which the immune system creates autoantibodies to ... non-profit Autoimmunity Research Foundation (ARF) explain that the antibodies ... human genes and gene products by hidden bacteria. , ... bacteria capable of causing human disease, But DNA discoveries ...
... Pharmaceuticals, a division of Wyeth (NYSE: ... has granted marketing authorization for CONBRIZA(TM) (bazedoxifene), a ... of postmenopausal osteoporosis in women at increased risk ... risk treatment guidelines and assessment tool for calculating ...
... Study shows those who respond to lapatinib survive longer, , , ... be used to treat aggressive inflammatory breast cancer, suggest the ... cancer accounts for up to 6 percent of all invasive ... to the researchers. Symptoms include rapid onset of swelling, ...
... to mirror Mandela,s values NEW YORK, April 27 46664 ... the world to support the creation of an official ... Mr. Mandela,s birthday. This celebration of Nelson Mandela,s life will ... recognize their individual power to make an imprint and help ...
Cached Medicine News:Health News:Thermal Angel Supports Infection Control During the Golden Hour 2Health News:As Health Reform Takes Shape, Leading Medical and Public Health Organizations Join Effort to Keep Obesity Front and Center 2Health News:As Health Reform Takes Shape, Leading Medical and Public Health Organizations Join Effort to Keep Obesity Front and Center 3Health News:As Health Reform Takes Shape, Leading Medical and Public Health Organizations Join Effort to Keep Obesity Front and Center 4Health News:'Autoantibodies' may be created in response to bacterial DNA 2Health News:Wyeth's CONBRIZA Approved in the European Union for Treatment of Postmenopausal Osteoporosis in Women at Increased Risk of Fracture 2Health News:Wyeth's CONBRIZA Approved in the European Union for Treatment of Postmenopausal Osteoporosis in Women at Increased Risk of Fracture 3Health News:Wyeth's CONBRIZA Approved in the European Union for Treatment of Postmenopausal Osteoporosis in Women at Increased Risk of Fracture 4Health News:Drug May Help Against Inflammatory Breast Cancer 2Health News:46664 and the Nelson Mandela Foundation Call for Establishment of Global 'Mandela Day' 2Health News:46664 and the Nelson Mandela Foundation Call for Establishment of Global 'Mandela Day' 3Health News:46664 and the Nelson Mandela Foundation Call for Establishment of Global 'Mandela Day' 4Health News:46664 and the Nelson Mandela Foundation Call for Establishment of Global 'Mandela Day' 5
RM-1970 Mucotome ergonomic design with E-Type coupling, designed for mucosal repair surgery....
RM-1900 Dermatome developed for reconstructive plastic surgery with E-Type coupling. Dermatome with 50 mm cutting width....
... The New Model C Dermatome - reaching ... switch - Push forward to operate in the ... mode. Autoclavable - the entire instrument and hose ... - Cut grafts in 2-, 3-, or 4-inch ...
A finely parallel striated (scratched) clear plastic membrane encapsulated between glass plates....
Medicine Products: