Navigation Links
Results Of VYVANSE(TM) (lisdexamfetamine dimesylate) Effect Size Analysis Presented at Major Scientific Meeting
Date:10/26/2007

Analysis of study showed effect size of VYVANSE ranged from 1.39 to 1.73

BOSTON, Oct. 26 /PRNewswire-FirstCall/ -- Shire plc (LSE: SHP, Nasdaq: SHPGY, TSX: SHQ), the global specialty biopharmaceutical company, today announced results from an analysis of VYVANSE(TM) (lisdexamfetamine dimesylate) effect size. These findings were presented today at a national meeting of psychiatrists in Boston. Effect size is a standardized and scientific method of comparing effectiveness of medications evaluated in different studies for the same condition. In general, effect sizes are categorized as small (0.2), medium (0.5) and large (0.8).

An analysis of the phase III pivotal study in pediatric patients with Attention Deficit Hyperactivity Disorder (ADHD) showed the effect size of VYVANSE was 1.39, 1.42 and 1.73 for 30 mg, 50 mg and 70 mg, respectively. This analysis was conducted to establish that the effect size of VYVANSE was due to the medication's effectiveness and not due to two potential influencing factors: the precision of measurement as indexed by standard deviation of endpoint scores, and the size of baseline versus endpoint placebo effect. The findings show that neither of these factors played a role in determining the effect size of VYVANSE. The relationship between effect size and clinical benefit has not been established.

"I'm encouraged that in our analysis, VYVANSE showed a large effect size," said Stephen Faraone, Ph.D., director of medical genetics research and head of child and adolescent psychiatry research at SUNY Upstate Medical University, who led the analysis. "This further supports our belief that VYVANSE is an effective treatment option for children with ADHD."

VYVANSE is a prodrug of d-amphetamine and is approved in the U.S. for the treatment of ADHD in children aged 6 to 12 years.

About ADHD

Approximately 7.8 percent of all school-age children, or about 4.4 million U.S. children aged 4 to 17 years, have been diag
'/>"/>

SOURCE Shire plc
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results
2. Diagnosing Diabetes: Immediate HbA1c Results Improve Glycemic Control
3. Cell Therapeutics, Inc. Management to Discuss Todays Announcement of Interim Pixantrone Study Results
4. Sygnis Pharma AG announces date for presentation of clinical results
5. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
6. Positive Aggrastat Results Featured in the Journal of the American College of Cardiology
7. Pixantrone Combination Therapy for First-line Treatment of Aggressive Non-Hodgkins Lymphoma Results in Reduction in Severe Toxicities Including Heart Damage When Compared to Doxorubicin-based Therapy
8. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
9. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
10. Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis
11. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2014)... , July 21, 2014 Thoratec Corporation ... device-based mechanical circulatory support therapies to save, support and ... its operating results for the second quarter of fiscal ... company will hold a conference call to discuss its ... parties, at 1:30 p.m., Pacific Daylight Time (4:30 p.m., ...
(Date:7/21/2014)... /PRNewswire-iReach/ -- Top Brooklyn Pediatrician Dr. ... article, which suggests that caffeine may be dangerous, according ... A few decades ago parents ... but now it happens rather frequently, according to an ... in the journal Pediatrics, discussed a new study, which ...
(Date:7/21/2014)... 2014 UBM Medica US announces that ... community for primary care clinicians offers a photo collection ... victims of a variety of summer scourges.  ... a host of medical menaces: poison ivy, tick-borne infections, ... the highlights covered on Consultantlive,s topic center that includes ...
Breaking Medicine Technology:Thoratec Schedules Second Quarter Conference Call, Webcast 2Dr. Michael Gabriel a Brooklyn Pediatrician Comments on an Article, Which Suggests Caffeine May Be Dangerous for Children 2ConsultantLive Presents Special Coverage of Summer Scourges 2ConsultantLive Presents Special Coverage of Summer Scourges 3
... 2007 - An alarming study,that appeared in the ... of the American Cancer Society), reports that one-third ... hormonal breast,cancer treatment tamoxifen citrate, discontinue therapy early.(1), ... a major issue that may negatively affect treatment ...
... 2007 - ArQule, Inc.,(NASDAQ: ARQL) today announced that ... for oral presentation the,Company's abstract for ARQ 197 ... a Selective Inhibitor of the c-Met Receptor in ... Annual Meeting, June,1-5, 2007, in Chicago. This presentation ...
Cached Medicine Technology:One-Third of Patients Discontinue Common Breast Cancer Therapy 2One-Third of Patients Discontinue Common Breast Cancer Therapy 3ArQule Announces Acceptance of Clinical Data on ARQ 197, c-Met,Inhibitor, for Oral Presentation at ASCO 2ArQule Announces Acceptance of Clinical Data on ARQ 197, c-Met,Inhibitor, for Oral Presentation at ASCO 3ArQule Announces Acceptance of Clinical Data on ARQ 197, c-Met,Inhibitor, for Oral Presentation at ASCO 4
(Date:7/22/2014)... Pompano Beach, Florida (PRWEB) July 22, 2014 ... and alcohol treatment center located in Pompano ... of approval from the Joint Commission, an independent ... the United States. Accreditation signifies that the quality ... the Joint Commission standards for safety and performance. ...
(Date:7/22/2014)... Coral, FL (PRWEB) July 22, 2014 ... has opened registration for multiple upcoming real estate investing ... These potentially life-changing events are designed to introduce people ... using in the Canadian market. , A total of ... over a period of three weeks. The goal is ...
(Date:7/22/2014)... 22, 2014 2014 ST. JOHN’S, CONSUMER ... to announce the 2014 Top Service Providers in their ... extend heartfelt congratulations to all this year’s winners; your ... of St. John’s. , Each year across Canada, Consumer ... responses of thousands of consumers and businesses. All winners ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 Recently, 2014quinceaneradresses.com, ... has announced its latest assortment of blue and ... promotional prices on these special Quinceanera gowns, hoping to ... before July 30 can get a discounted price, up ... very glad to announce these new items. As one ...
(Date:7/22/2014)... Carolina (PRWEB) July 22, 2014 One woman ... solution managed to lose 20 pounds. Unfortunately, the weight loss ... nauseated for the duration of her time using the pill, ... woman experienced heart flutters and insomnia as a result of ... a heart attack at the age of 37 because of ...
Breaking Medicine News(10 mins):Health News:Florida Drug and Alcohol Addiction Treatment Center Receives Joint Commission Seal of Approval 2Health News:Florida Drug and Alcohol Addiction Treatment Center Receives Joint Commission Seal of Approval 3Health News:Brick Buy Brick Announces Multiple 1-Day Real Estate Workshops Coming to Toronto 2Health News:2014 St. John's Consumer Choice Award Winners 2Health News:2014 St. John's Consumer Choice Award Winners 3Health News:2014 St. John's Consumer Choice Award Winners 4Health News:Blue and White Quinceanera Dresses at Low Prices Offered by 2014quinceaneradresses.com 2Health News:SlimPlate System Urge Women to Shun Controversial Weight Loss Pills for Healthier Methods Like Portion Control 2
... the best way to fix the broken health care system is a ... from an employment based insurance system. , ... Brookfield, Wisconsin (PRWEB) November ... to fix the broken health care system is a complete overhaul, they ...
... two radio frequency modes into one device. The Accent Dual Mode RF ... on both shallow and deep tissue depths. The technology is the latest ... and Laser Center. , ... New York, NY (PRWEB) November 13, 2008 ...
... 13 TheraQuest Biosciences, Inc. a,development stage ... U.S.,Food and Drug Administration (FDA) has accepted ... its abuse deterrent extended release,strong opioid. TQ-1015 ... deterrent technology., Najib Babul, PharmD, Chief ...
... of members, SEIU officials shut down,California offices ahead ... Caregivers who work in,California hospitals, nursing homes, and ... offices of their national union, the Service,Employees International ... United Healthcare Workers-West (UHW), a,local union that has ...
... helps prevent malaria, ALEPE, Cote d,Ivoire, Nov. ... and their partners worldwide helped Cote d,Ivoire,s,National Program ... health,campaign November 11 that will vaccinate 3.5 million ... the country with bed nets to,stop the spread ...
... 12 Amilpar,(BOVESPA: AMIL3, Bloomberg: AMIL3 BZ and Reuters: AMIL3.SA), ... for the third quarter of 2008., 3rd Quarter ... at the end of September, up 18.2% ... than the previous quarter. -- Adjusted Operating Revenues totaled ...
Cached Medicine News:Health News:Employers Want National Approach to Health Care—Still Believe Employer-Based System Works Best: New Survey Looks At Attitudes toward Health Care Reform and Major Health Care Issues. 2Health News:Employers Want National Approach to Health Care—Still Believe Employer-Based System Works Best: New Survey Looks At Attitudes toward Health Care Reform and Major Health Care Issues. 3Health News:Accent Dual Mode Skin Tightening Laser is Latest Offering from Juva Skin Center 2Health News:TheraQuest's IND for Abuse Deterrent Strong Opioid (TQ-1015) Accepted by FDA 2Health News:Healthcare Workers Picket Their National Union to Protect Their Voice for Patients 2Health News:Photo: United Methodist Church, Partners Launch Life-Saving Campaign in Cote d'Ivoire 2Health News:Amilpar Revenues Grow 28% in the First 9 Months of 2008 and 4.5% Over Previous Quarter 2
Open wire loops decrease the chance of interfering with instruments, Designed to retract the eyelid during ophthalmic microsurgery or minor office procedures...
For rotating nucleus during phacoemulsification, Also useful for dislocating the nucleus into the anterior chamber during extracapsular cataract extraction, 45, Blunt, Forked, 9.0mm from end...
... drape has two perforations which ... to various single or bilateral ... Refractive drape has two perforations ... adapts to various single or ...
Angled 45, 9mm from end, Longer design from bend to tip allows for easier placement of viscoelastic to all meridians, Dome shape, extra smooth tip...
Medicine Products: