Navigation Links
Results From Study Show Promising Efficacy and Safety Results for Corthera's Relaxin in Acute Heart Failure
Date:3/29/2009

Data Presented at Late-Breaking Clinical Trials Session at ACC 58th Annual Scientific Session; Results Published On-Line in The Lancet

SAN MATEO¿ Calif.¿ March 29 /PRNewswire/ -- Corthera Inc. today announced that results from Pre-RELAX-AHF, the Phase II portion of a Phase II/III multicenter, randomized, double-blind, placebo-controlled international study, demonstrated promising efficacy and safety for relaxin, the company's investigational drug for treatment of acute heart failure (AHF). The report containing the detailed study results is being published on-line in the medical journal, The Lancet.

The data from 234 patients in eight countries showed that when administered with standard-of-care therapy for acute heart failure, relaxin caused rapid, substantial and sustained relief from dyspnea (breathlessness). Relaxin also demonstrated consistent trends in improvement of the hospital course of patients, prevention of heart failure worsening during hospitalization, shortening of in hospital stay and improved longer-term outcomes following discharge when compared to placebo. John R. Teerlink, M.D., professor of medicine, University of California San Francisco, Director of Heart Failure, Veterans Affairs Medical Center, San Francisco and co-principal investigator of the study, presented the findings today at a late-breaking clinical trials session at the American College of Cardiology's (ACC) 58th Annual Scientific Session in Orlando, Fla.

"The results of the study clearly indicated favorable treatment effects on symptoms, signs and outcomes in patients hospitalized with AHF," said Teerlink. "The use of relaxin led to considerable improvement in dyspnea when compared to placebo and lasted up to 14 days, longer than any therapy studied. In this study, relaxin administration was safe and well tolerated. These results provide a clear direction for the Phase III study."

Marco Metra,
'/>"/>

SOURCE Corthera Inc.
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related medicine technology :

1. Impulse Dynamics Announces Pivotal Results at the American College of Cardiology Annual Meeting Late-Breaking Session
2. Neurocrine Announces Top-Line Results From 702 Study (Lilac PETAL Study) of Elagolix for Treatment of Endometriosis Pain
3. Oramed Pharmaceuticals to Present Oral Insulin Phase 2A Trial Results at the Upcoming Annual Meeting of the ADA (June 5-9, New Orleans, LA)
4. Following Encouraging Results Anthera to Continue IMPACTS Trial for the Prevention of Acute Chest Syndrome in Patients With Sickle Cell Disease
5. First Year Results of the AXA Research Fund: Over Euro 13 Million Allocated for Research in 2008
6. Calixa Therapeutics Announces Positive Phase 1 Results for CXA-101, a Novel Intravenous Cephalosporin Antibiotic with Excellent Anti-Pseudomonal Activity
7. Results From Efficacy and Safety Study of Cortheras Relaxin in Acute Heart Failure to be Presented at Late-Breaking Clinical Trials Session at ACC 58th Annual Scientific Session
8. Cephalon Announces Positive Results From a Phase Two Study of NUVIGIL in Bipolar Depression
9. Poniard Pharmaceuticals Reports Fourth Quarter and Year End 2008 Financial Results and Provides a Corporate Update
10. Video: Provectus PV-10 Interim Phase 2 Safety and Efficacy Results are as Good as or Better than Phase 1 Results
11. The Lancet Publishes Two-Year Results of Abbotts Fully Bioabsorbable Drug Eluting Stent

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/30/2009)...Newswire-FirstCall/ -- MedQuist Inc. (Nasdaq: MED...ical documentation services, today announced that ...ons, Inc. (Nuance) under which MedQuist will now l...ine and processing software for use in SpeechQ of ...recognition application for all medical discipline...
(Date:11/30/2009)...ewswire/ -- Reportlinker.com announces that a new ...ue: ,, Diabetes Diagnostics - A Global Market ...164347/Diabetes-Diagnostics---A-Global-Market-Pers...driven by a steady increase in the number of peopl...nd developing parts of the world, and increase in ...
(Date:11/30/2009)...-- Dr. Jocelyn Rapelyea, Associate Director of Bre...University Medical Center in Washington, D.C., dem...t-Specific Gamma Imaging (BSGI) can be localized u...as well, as for pre-operative localization today a...f North America (RSNA). ,, BSGI was conducted u...
Breaking Medicine Technology:MedQuist Signs Agreement Extending Use of Real-Time Speech Recognition Engine to Wide Range of Medical Specialties 2Reportlinker Adds Diabetes Diagnostics - A Global Market Perspective 2Reportlinker Adds Diabetes Diagnostics - A Global Market Perspective 3Reportlinker Adds Diabetes Diagnostics - A Global Market Perspective 4Reportlinker Adds Diabetes Diagnostics - A Global Market Perspective 5Reportlinker Adds Diabetes Diagnostics - A Global Market Perspective 6Reportlinker Adds Diabetes Diagnostics - A Global Market Perspective 7Reportlinker Adds Diabetes Diagnostics - A Global Market Perspective 8Reportlinker Adds Diabetes Diagnostics - A Global Market Perspective 9Breast-Specific Gamma Imaging Identifies Occult Lesions Using Multi-Modality Imaging for Biopsy 2Breast Cancer Numbers Dip Most in Wealthy Urban Areas 50200 1Breast Cancer Numbers Dip Most in Wealthy Urban Areas 50200 2The Psychology of Celebrity Worship 50198 1The Psychology of Celebrity Worship 50198 2The Psychology of Celebrity Worship 50198 3Discus Dental Files Suit to Protect BriteSmile 28R 29 Trademark 50197 1Discus Dental Files Suit to Protect BriteSmile 28R 29 Trademark 50197 2
...June 4 AstraZeneca (NYSE:,AZN) today announced th...n,(sNDA) to the U.S. Food and Drug Administration ...RT(R) (budesonide/formoterol fumarate dihydrate),I...eatment of asthma in,pediatric patients ages 6 to ...the long-term maintenance treatment of asthma in p...
... 4 Semafore Pharmaceuticals Inc.,today reported i...ct,candidate, SF1126, a targeted pan-PI3 kinase (P...mors. SF1126 is the first PI3 kinase inhibitor to ...ltiple myeloma trials., The data from the solid t...ed in a twice-weekly I.V. infusion at exposure lev...
Other Medicine Technology:AstraZeneca Submits an sNDA for SYMBICORT(R) for the Treatment of Asthma in Children as Young as Age Six 2AstraZeneca Submits an sNDA for SYMBICORT(R) for the Treatment of Asthma in Children as Young as Age Six 3AstraZeneca Submits an sNDA for SYMBICORT(R) for the Treatment of Asthma in Children as Young as Age Six 4AstraZeneca Submits an sNDA for SYMBICORT(R) for the Treatment of Asthma in Children as Young as Age Six 5AstraZeneca Submits an sNDA for SYMBICORT(R) for the Treatment of Asthma in Children as Young as Age Six 6Semafore Pharmaceuticals Reports Positive Interim Results from a Phase I Study of SF1126, a Targeted Pan-PI3K Inhibitor, in Patients with Advanced Solid Tumors 2Semafore Pharmaceuticals Reports Positive Interim Results from a Phase I Study of SF1126, a Targeted Pan-PI3K Inhibitor, in Patients with Advanced Solid Tumors 3
(Date:11/30/2009)...lics tend to drink heavily more often than younger...30 (HealthDay News) -- Older people who are proble... counterparts, a new report finds, possibly becaus...t. , According to a study released this month,... consume more than 40 drinks a week, on average. B...
(Date:11/30/2009)..., ENGLEWOOD, Colo., Nov. 30 Bax...ation discussing what "culture of safety" means in...um presentation, "Creating a Culture of Safety in...fessionals discussing their experiences with cultu...safety in pharmacy and the role of technology in e...
(Date:11/30/2009)... MINNEAPOLIS, Nov. 30 A new study ...emental Medicare insurance customers have a curren...Medicare coverage. The figure is up from 20% in 2...switch" measure has been a leading indicator of ac... some intention to switch actually will leave thei...
(Date:11/30/2009)...butes rise to more women having babies later in li...ws) -- A growing number of children in the United ...researchers say. , The overriding reason, exper.... , Data from 10 regional registries of birth d...ong U.S. children increased by 31 percent between ...
(Date:11/30/2009)... ShowMyPC has released an online serv...PC; from anywhere. This is the first hosted servic...Remote Desktop program. Result, blazing fast perfo... Santa Clara, CA (PRWEB) November 30,...osted Remote Access Service that uses the familiar...
Breaking Medicine News(10 mins):Health News:Binge Drinking Not Just a Rite of the Young 2Health News:Baxa to Sponsor ASHP Midday Symposium: Creating a Culture of Safety in Pharmacy, A Panel Discussion on Lessons Learned 2Health News:Baxa to Sponsor ASHP Midday Symposium: Creating a Culture of Safety in Pharmacy, A Panel Discussion on Lessons Learned 3Health News:More Seniors Considering Health Insurance Switch 2Health News:U.S. Records Increase in Kids With Down Syndrome 2Health News:U.S. Records Increase in Kids With Down Syndrome 3Health News:ShowMyPC Provides First Online Service in the World to Access Personal Computers from Anywhere Using Microsoft Remote Desktop 2
... of ten regular food items aimed specifically at c...f high levels of sugar, fat or sodium - according ...he July issue of the UK-based journal Obesity Rev...roportion of calories from sugar. Approximately on...
...spital Management announced the appointment of Gre...Officer of American Hospital Management ...uly 14 American Hospital Management,Company (AHMC...g Medical Education, Quality Programs and Medical ...
...gery Services of Fredericksburg is First in Virgin...X(TM), FREDERICKSBURG, Va., July 14 A laser-assi...kin is now being offered at Plastic,Surgery Servic...power laser to,eliminate fat cells in areas such a...
... helps them return to prior playing level 83% of t...lthDay News) -- One of the country,s leading sport...ies on sprained elbows in young athletes, a fact t...and putting their arms at risk, said co-author Dr....
...ity, Web-Enabled and Vendor-Neutral, CardioPACS(TM...operability and Efficiency, OAKLAND, Calif., July...ly integrated cardiovascular imaging and informati...PACS 5.0 is a next generation PACS solution, offer...
...uly 14 MS -- Every student has his or her,way of ...tudious and,regimented, working hard for good grad...ase. Still, others prefer more of the social aspec...l year. Here are some ideas to,consider, courtesy ...
Other Medicine News:Health News:89 percent of children's food products provide poor nutritional quality 2Health News:89 percent of children's food products provide poor nutritional quality 3Health News:89 percent of children's food products provide poor nutritional quality 4Health News:American Hospital Management Company Appoints Gregory Ciottone, MD as Chief Medical Officer 2Health News:American Hospital Management Company Appoints Gregory Ciottone, MD as Chief Medical Officer 3Health News:American Hospital Management Company Appoints Gregory Ciottone, MD as Chief Medical Officer 4Health News:American Hospital Management Company Appoints Gregory Ciottone, MD as Chief Medical Officer 5Health News:Latest Laser Fat Removal Procedure Now Available 2Health News:Elbow Injuries on Rise Among Young Athletes 2Health News:Elbow Injuries on Rise Among Young Athletes 3Health News:LUMEDX Introduces Next Generation Cardiology PACS Solution 2Health News:Good Habits for School Success 2
... ARUP Laboratories is a national reference laborat...y research and development. ARUP offers an extensi...tests in clinical and anatomic pathology. Owned by...s include more than half of the nation's universit...
... ARUP Laboratories is a national reference laborat...y research and development. ARUP offers an extensi...tests in clinical and anatomic pathology. Owned by...s include more than half of the nation's universit...
... ARUP Laboratories is a national reference laborat...y research and development. ARUP offers an extensi...tests in clinical and anatomic pathology. Owned by...s include more than half of the nation's universit...
... ARUP Laboratories is a national reference laborat...y research and development. ARUP offers an extensi...tests in clinical and anatomic pathology. Owned by...s include more than half of the nation's universit...
Medicine Products: