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Results From Pilot Trial of PLC's RenalGuard® Published in International Journal of Cardiology
Date:1/17/2012

MILFORD, Mass., Jan. 17, 2012 /PRNewswire/ -- PLC Systems Inc. (OTC: PLCSF), a company focused on innovative medical device technologies, today announced that an article summarizing the results from its U.S. pilot trial for RenalGuard® has been published online in the December 26, 2011 International Journal of Cardiology, a peer-reviewed journal affiliated with the International Society of Adult Congenital Heart Disease. The results from this trial, which was completed in 2007 and presented at the American College of Cardiology conference in March 2009, confirmed that RenalGuard System™ "is safe and dynamically balances volume hydration."   

The trial was conducted in four clinical sites in the U.S. in 2006 and 2007, with a total of 23 patients enrolled, and was designed to evaluate the safety of RenalGuard System and RenalGuard Therapy®, under an Investigational Device Exemption (IDE) approved by the U.S. Food and Drug Administration (FDA).  The results of this feasibility study illustrate that RenalGuard can safely help maintain high rates of urine output without significant hemodynamic or systemic adverse reactions.   

PLC's U.S. pivotal trial to study the efficacy of RenalGuard Therapy and RenalGuard System in the prevention of Contrast-Induced Nephropathy (CIN) is currently underway under the supervision of Principal Investigators Charles Davidson, MD, Professor of Medicine, Northwestern University Medical School, Richard J. Solomon, MD, Professor of Medicine, University of Vermont College of Medicine and Roxana Mehran, MD, Professor of Medicine at Mount Sinai School of Medicine.

The International Journal of Cardiology article can be accessed at the following link: 

SOURCE PLC Systems Inc.
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