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Resolvyx Pharmaceuticals and Celtic Therapeutics Enter Final Agreement in Ophthalmology
Date:1/10/2011

administered as a topical eye drop, produced dose-dependent, significant improvement on the primary endpoints for both the signs and symptoms of dry eye, and was generally shown to be safe and well tolerated in a large placebo-controlled Phase II study.

"We are delighted to be partnered with Celtic Therapeutics in progressing Resolvins to treat dry eye syndrome and other eye disease," said Jamie Nichols, Chief Operating Officer at Resolvyx. "This innovative deal with Celtic Therapeutics will provide the necessary capital and clinical expertise to pursue our aggressive development plans for RX-10045 while allowing Resolvyx to share in the future success of this exciting program" said Greg Weinhoff, Executive Chairman. "Resolvyx can now dedicate its internal resources to developing the exceptional therapeutic potential of resolvins for non-ophthalmic diseases."

"We are very pleased to announce that we have concluded the acquisition of this late-stage program," commented Stephen Evans-Freke and Peter B. Corr, co-founders and Managing General Partners of Celtic Therapeutics Holdings L.P.  "We look forward to a close and successful alliance with Resolvyx to optimize the medical potential and financial returns from this exciting class of novel anti-inflammatory molecules in the ophthalmology field.  If approved, RX-10045 should provide superior efficacy to current therapeutic options in Dry Eye.  We are eager to explore the activity of resolvins in additional ophthalmic indications as well."

About Resolvins

Resolvins are a recently discovered family of naturally-occurring, small molecule lipid mediators that can be targeted to treat a wide range of diseases. In particular, resolvins act to protect healthy tissue during an inflammatory response to infection, injury or other environmental challenge, and then act to resolve inflammation and promote healing after the insult has passed. Resolvins are shown to be highly potent
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