Navigation Links
Researchers at Axial Biotech Develop a DNA Test for Scoliosis
Date:9/11/2008

Study results presented at the Scoliosis Research Society Meeting in Salt

Lake City

SALT LAKE CITY, Sept. 11 /PRNewswire/ -- Researchers at Axial Biotech, Inc., announced today that they have identified specific genetic markers for scoliosis. The data from this research made it possible for the development of a DNA-based prognostic test for spinal curve progression in patients with Adolescent Idiopathic Scoliosis.

This groundbreaking research was presented to members of the Scoliosis Research Society (SRS) on Thursday, September 11, 2008 at the 43rd Annual SRS Meeting held in Salt Lake City.

Scoliosis is an inherited disease that occurs when the spine twists and develops a sideways curve. When the cause of scoliosis is unknown, for patients between the age of 9 and 13, it is called Adolescent Idiopathic Scoliosis (AIS). If an AIS curve progresses, the most widely accepted treatments are serial spinal bracing or spinal fusion surgery.

The scoliosis research, which began in 2003 and ended last month, involved collecting DNA samples from over 9,000 patients from 85 clinical sites throughout the world. All patient samples were analyzed on several technology platforms and specific disease classifications were evaluated by the review of x-rays and medical records provided from physicians who were treating patients enrolled in this study.

"These landmark studies have provided researchers with greater insights into the genetic markers associated with spinal curve progression," stated Ken Ward, M.D., Chief Scientific Officer for Axial Biotech. "The AIS Prognostic Test, which can determine whether a child has a mild or more severe likelihood of curve progression, at the very first presentation of symptoms, may provide comfort to thousands of children and their families every year. This study reinforces the importance of research that may lead to new treatment options for scoliosis patients."

"We believe that the use of DNA-based testing to determine the likelihood of disease progression will initiate a new era of improvements in spine health," says Jim Ogilvie, M.D, Chief Medical Consultant. "From a clinical standpoint, this test delivers the promise of personalized medicine to spine surgeons who will now have the opportunity to determine the likely disease progression for an individual AIS patient, and can make evidence-based recommendations for patient-specific treatment options."

Geneticists at Axial Biotech are currently analyzing the data from the 9,000 patients studied, to identify genetic factors that initially cause this disease, and the company anticipates that soon it may largely understand the specific biology for this aggressive and crippling disease, and hopes to develop molecular treatments for scoliosis patients.

The AIS prognostic test will be marketed under the trade name of ScoliScore(TM) and will be marketed and distributed by DePuy Spine, a Johnson & Johnson company.

About Axial Biotech

Axial Biotech, Inc. develops molecular diagnostic assays and motion preservation technologies for common spinal diseases and disorders. Axial has developed the first DNA-based prognostic test for Adolescent Idiopathic Scoliosis. Axial is accredited by the College of American Pathologists (CAP) and is certified to comply with the Clinical Laboratory Improvement Amendments (CLIA). Founded in 2002, Axial is based in Salt Lake City, Utah.


'/>"/>
SOURCE Axial Biotech, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. K-State Researchers Awarded Nearly $1 Million to Test Remedies, Investigate Link Between E. Coli and Distillers Grains
2. Rapid Test for Pathogens Developed By K-State Researchers Could Be Used to Detect Diseases Used By Bioterrorists
3. Dallas Researchers Find Compression Stockings Improperly Used
4. Snapshots of Eyes Could Serve as Early Warning of Diabetes or Diabetic Eye Disease, U-M Researchers Report
5. Pediatric Researchers Find Possible Master Switch Gene in Juvenile Arthritis
6. GlaxoSmithKline Collaborates with National Cancer Institute to Make Large Body of Cancer Cell Genomic Data Available to All Cancer Researchers
7. Karmanos Cancer Institute Researchers Show Phase I Immunotherapy with Armed T Cells Improve Overall Survival of Metastatic Breast Cancer Patients
8. NARSAD Researchers Identify Specific Genes and Family Traits Linked to Schizophrenia, Bipolar Disorder and Depression
9. Cardiovascular Researchers Use MEDIHONEY(TM) on Sternal Infections Following Open-Heart Procedures
10. Peregrine Researchers Present New Preclinical Data at AACR Annual Meeting Confirming Unique Anti-Tumor Mechanism of Bavituximab
11. Karmanos Researchers Study the Impact of Galectin-3 on Breast Cancer Disparity in Caucasian and Asian Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/9/2016)... Feb. 9, 2016   AllCare Plus Pharmacy ... Gold Seal of Approval ® for Home ... performance standards. The Gold Seal of Approval ® ... commitment to providing safe and effective care.  ... Pharmacy underwent a rigorous on-site survey in January 2016. ...
(Date:2/9/2016)... , Feb. 9, 2016 Hearing protection devices ... sound energy transmitted to the inner ear. Hearing protection ... bands. These devices are recommended for users exposed to ... Earplugs refer to HPD that are inserted in the ... are designed to provide more natural sound perception with ...
(Date:2/9/2016)... LONDON , Feb. 9, 2016 The new report "Global Blood ... Spearhead Acuity Business Research & Consulting group reveals that global market ... 17,770.3 million in 2014 and expected to grow to US$ 24,830.1 ... 2019. North America , Europe ... , Middle-East and Africa ...
Breaking Medicine Technology:
(Date:2/10/2016)... ... February 10, 2016 , ... A ... Ohio Safety Congress and Expo event March 9-11, 2016. Hosted by Ohio's Bureau ... Center. , As the longest running and largest worker's compensation event in ...
(Date:2/10/2016)... MD (PRWEB) , ... February 10, 2016 , ... ... to make Everseat digital self-scheduling readily available to physicians. The integration ... patients can find and select appointments via Everseat’s free mobile app. , The ...
(Date:2/10/2016)... ... February 10, 2016 , ... ... Jacksonville, FL 32224, February 26th: Amateur & Professional Divisions - Time: 7:00pm ... 7:00pm – 10:00pm | Ticket Prices $30, Social Media: http://www.USPoleSportsFed.org , ...
(Date:2/10/2016)... ... 10, 2016 , ... Workrite Ergonomics, who is celebrating their 25th year of ... to being an internationally recognized leader in their industry. , "We are very proud ... President of Workrite. “Workrite recognized the importance of good ergonomics before most of ...
(Date:2/10/2016)... ... February 10, 2016 , ... Anxiety of older Americans over ... of Medicare Part D a decade ago, according to The Senior Citizens League ... on how they are coping with rapidly rising costs. “The implications are chilling, ...
Breaking Medicine News(10 mins):