Navigation Links
Researchers Use Magnetism to Target Cells to Animal Arteries
Date:1/7/2008

- Magnetically Guided Nanoparticles May Deliver Treatments to Human Organs -

PHILADELPHIA, Jan. 7 /PRNewswire-USNewswire/ -- Scientists have used magnetic fields and tiny iron-bearing particles to drive healthy cells to targeted sites in blood vessels. The research, done in animals, may lead to a new method of delivering cells and genes to repair injured or diseased organs in people.

(Photo: http://www.newscom.com/cgi-bin/prnh/20080107/DC10966 )

The study team, led by Robert J. Levy, M.D., the William J. Rashkind Chair of Pediatric Cardiology at The Children's Hospital of Philadelphia, loaded endothelial cells, flat cells that line the inside of blood vessels, with nanoparticles, tiny spheres nanometers in diameter. The nanoparticles contained iron oxide.

Using an external, uniform magnetic field, Levy's team directed the cells into steel stents, small metal scaffolds that had been inserted into the carotid arteries of rats. The uniform magnetic field created "magnetic gradients," local regions of high magnetic force that magnetized both the nanoparticles and the stents, thus increasing the attraction between the particles and their target.

The study appears in the Proceedings of the National Academy of Sciences, published online on Jan. 7. Dr. Levy's group from Children's Hospital collaborated with engineers from Drexel University and Duke University.

"This is a novel strategy for delivering cells to targets in the body," said Levy, who added that previous researchers have pursued other, less successful approaches to introduce endothelial cells to diseased blood vessels, in the developing medical field of cell therapy.

Levy's team created nanoparticles, approximately 290 nanometers across, made of the biodegradable polymer, polylactic acid, and impregnated with iron oxide. (A nanometer is a millionth of a millimeter;
'/>"/>

SOURCE The Children's Hospital of Philadelphia
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Novel Mechanism for Long-Term Learning Identified by Carnegie Mellon Researchers
2. Researchers Train the Immune System to Deliver Virus That Destroys Cancer in Lab Models
3. Researchers Develop New Procedure to Screen All 46 Human Chromosomes to Identify Abnormalities in Embryos
4. Potential Breakthrough Cancer Treatment Emerges from MIPS-Funded Clinical Trial Teaming CSA Medical Inc. and University of Maryland Researchers
5. Researchers Report First Successful Treatment of Chronic Traumatic Brain Injury
6. 454 Sequencing(TM) in Science Today: Researchers Uncover a Genetic Basis for Different Social Behaviors in Wasps
7. U. of Md. Researchers to Develop Devices to Revolutionize Drug Research
8. K-State Researchers Bringing Expertise to Kansas City Symposium on Disease and National Security
9. Peregrine Researchers Report Data Showing Bavituximabs Potential to Shrink Human Prostate Tumors in Model of Relapsed Disease
10. Researchers Identify Virus Possibly Responsible for Declining Honeybee Population Using 454 Sequencing Technology from Roche
11. Cleveland Clinic Researchers Identify Mechanism Behind Platelet Function and Potentially Fatal Blood Clot Formation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... , Sept. 2, 2014  Amgen ... the submission of a Marketing Authorization Application ... via the centralized procedure for talimogene laherparepvec ... with melanoma that is regionally or distantly ... administered as an intralesional injection that is ...
(Date:9/2/2014)... FRANCISCO, Calif. , Sept. 2, 2014   Veracyte, ... Bonnie H. Anderson , president and chief executive officer, ... Morgan Stanley Global Healthcare Unplugged Conference 2014 on Monday, September ... York . The live audio webcast and ... http://investor.veracyte.com . Please connect to the website at least ...
(Date:9/2/2014)... Redspin, Inc., a leading provider of HIPAA ... an IT security advisory specifically for senior executives in ... presiding over the most dynamic period in the history ... Redspin,s President and CEO. "The goal of our advisory ... understand why they need to elevate IT security to ...
Breaking Medicine Technology:Amgen Submits Marketing Authorization Application For Talimogene Laherparepvec To The European Medicines Agency 2Amgen Submits Marketing Authorization Application For Talimogene Laherparepvec To The European Medicines Agency 3Amgen Submits Marketing Authorization Application For Talimogene Laherparepvec To The European Medicines Agency 4Amgen Submits Marketing Authorization Application For Talimogene Laherparepvec To The European Medicines Agency 5Amgen Submits Marketing Authorization Application For Talimogene Laherparepvec To The European Medicines Agency 6Veracyte to Present at the Morgan Stanley Global Healthcare Unplugged Conference 2014 2
... importance of dedicated information management systems for radiation ... most recent version of its MOSAIQ® Oncology Information ... Systems Society,s 2012 conference (HIMSS12), Feb. 20-24, in ... comprehensive OIS that centralizes traditional radiation oncology, particle ...
... Feb. 16, 2012  Cardium Therapeutics (NYSE Amex: ... previously announced sale of 17,857,143 shares of its common ... of approximately $5.0 million, before deducting placement agent,s fees ... investors participating in the offering purchased the shares at ...
Cached Medicine Technology:Elekta Highlights Latest Version of MOSAIQ Oncology Information System at HIMSS12 Meeting 2Cardium Announces Closing of $5.0 Million Equity Financing 2Cardium Announces Closing of $5.0 Million Equity Financing 3
(Date:9/2/2014)... Humility of Mary Health Partners will offer a ... Health Center, 1044 Belmont Ave. , The workshop includes an ... common health problems as well as tips on caring for ... on when to seek medical attention. , The morning ... Room; the evening session runs from 5:30 to 6:30 p.m. ...
(Date:9/2/2014)... 02, 2014 A little bit of ... sometimes the onset of irritability, sadness, or apathy can ... September 2014 Harvard Health Letter. , "Mood-related ... stresses. If they occur for long periods, cause significant ... to seek help," says Dr. Nancy Donovan, an instructor ...
(Date:9/2/2014)... Eric Jimenez and Leah Ashley announced ... revolutionary makeup application device. Designed to improve and accelerate ... the palm of women’s hands to help them get ... Me’s success lies in its patented technology. With a ... 15,000 pulses per minute, the device applies foundation evenly ...
(Date:9/2/2014)... B. E. Smith, the only full-service leadership solutions ... to lead a national chief executive officer ... Sioux Falls, S.D. The top executive search firm in ... more than 900 healthcare executives into organizations. , ... and nationally recognized leader in patient-centered care. It is ...
(Date:9/2/2014)... Syracuse, NY (PRWEB) September 02, 2014 ... A. Gadlage, M.D. & Associates in Duluth, GA and ... the EarQ team at the 2014 National ... in Cancun, Mexico. , While interacting with the former ... maintaining hearing health, the team provided free hearing screenings, ...
Breaking Medicine News(10 mins):Health News:HMHP Offers ‘Health at Home’ Workshop 2Health News:When a Mood Swing Signals Trouble, From the September 2014 Harvard Health Letter 2Health News:Color Me Launches With Ulta Beauty Revolutionary Makeup Application Device Gets Women Flawless in a Flash 2Health News:Color Me Launches With Ulta Beauty Revolutionary Makeup Application Device Gets Women Flawless in a Flash 3Health News:Sioux Falls Specialty Hospital Retains B. E. Smith to Recruit New CEO 2Health News:Sioux Falls Specialty Hospital Retains B. E. Smith to Recruit New CEO 3Health News:The EarQ Team Brings Hearing Health Awareness to the 2014 National Basketball Retired Players Association Annual Convention in Cancun 2
... a few glasses of wine enough to disrupt normal development, ... Just a few glasses of wine over a short period ... the Medical College of Georgia. , The initial signs ... include facial malformations such as a flat and high upper ...
... Benefit Muscular Dystrophy Research , ... Iselin, NJ (PRWEB) ... [Sanford-Brown Iselin] (SBI), in New Jersey, raised $11,000 for muscular ... the event are in support of local non-profit www.ryansquest.org ...
... to recent news,about Michigan,s first identified case of chronic ... issued the following statement., With hunting season fast ... a deer on a Kent County farm understandably has,created ... great state of Michigan. The deer farming industry in ...
... Surgery Seems to be the Provider of Choice for Recent,Big ... Next?, Months of constant cameras, mirrors all around and ... a major impact on how you feel,about the way you ... reality. Upon leaving the house contestants may undoubtedly spend,hours watching ...
... to $19 million, NATICK, Mass., Aug. 29 ... the U.S. District Court of,Marshall, Texas found two patents ... conduct during the prosecution of the patents,before the United ... previously found that certain Boston Scientific balloon,catheters and stent ...
... leadership and State delegations as a possible solution to national health ... ... 2008 -- If there has been any one consistent message offered ... the party platform initiative to resolve our national health care issues., ...
Cached Medicine News:Health News:Alcohol in Early Pregnancy May Prompt Fetal Cell Death 2Health News:Sanford-Brown Institute - Iselin Raises $11,000 for Ryan's Quest 2Health News:Deer Farm Industry in Michigan Issues Statement on the Recent Chronic Wasting Disease Case Identified on a Kent County Deer Farm 2Health News:MYA Makes Big Brother Stars Amazing! 2Health News:MYA Makes Big Brother Stars Amazing! 3Health News:Court Rejects Two Medtronic Patents 2Health News:Court Rejects Two Medtronic Patents 3Health News:AMD Global Telemedicine Inc. Invited to Attend Democratic National Convention 2
...
The Tew cranial/spinal retractor is designed for posterior fossa or intraspinal microsurgery where retraction is required. Clinical applications are: Posterior fossa microsurgery and intraspinal micr...
The Doro Halo retractor system is designed for all neurosurgical applications where retraction of the brain tissue and an armrest is required....
The Budde Halo brain retractor is designed for use in all intercranial procedures where retraction of delicate brain tissue is required....
Medicine Products: