Navigation Links
Researchers Pave Way for Tracking of Prostate Motion With a Single kV Imager During Arc Radiotherapy
Date:3/3/2010

PALO ALTO, Calif., March 3 /PRNewswire/ -- Researchers in the US and Denmark have made a breakthrough in image-guided targeting of prostate tumors during arc radiotherapy treatments. In research partially supported by Varian Medical Systems (NYSE: VAR), physicists at Stanford University (California, USA) and Aarhus University Hospital (Aarhus, Denmark) have devised a method for 'real-time' tracking of the prostate motion using Varian's On-Board Imager® that shows promise in paving the way for advanced clinical treatments.

Arc therapy techniques such as Varian's RapidArc® technology are fast and efficient radiotherapy treatments delivered in a continuous rotation of the treatment machine around the patient. The position of the target must be updated in real-time in order for the dynamic multi-leaf collimator (DMLC) to track tumor motion. To date, a combination of MV portal images and kV orthogonal images have been tested to achieve this.

"Acquiring mega-voltage images is not ideal during RapidArc because the DMLC can block the view of the target during the treatment," says Per Rugaard Poulsen, lead author of the research. "The kV image beam is not obscured by the treatment DMLC making the markers visible from all treatment angles, unlike with the MV beam."  

To test the system, arc radiotherapy was delivered to a 'motion phantom' implanted with fiducial markers while continuously imaging with the kV beam. The target position was determined from these images, acquired from different projections during the arc, enabling the researchers to determine information about its 3D motion. This single imager based DMLC tracking system was shown to have sub-millimeter accuracy for most types of prostate motion. Precise alignment of the treatment beam with the tumor position is vital in radiotherapy treatments, as it can reduce the likelihood of complications due to the treatment.  

"The results confirm what has been seen in simulation studies and show that the method is very robust to experimental uncertainties," adds Per Rugaard Poulsen. "We've demonstrated that image-based tracking during arc radiotherapy can be done completely without MV images, which is an important step along the way to image-based tracking during arc treatment delivery."

Corey Zankowski, Varian's senior director of product management, said, "This research paves the way for real-time tracking of the DMLC with tumor motion during advanced arc therapy treatments, which should allow clinicians to reduce treatment margins around the tumor. Varian is committed to working closely with industry experts and researchers to enhance treatment accuracy with the goal of improving treatment outcomes."

An upcoming publication from these researchers will focus on the application of this method to respiratory motion.

Publication: Poulsen et al. IJROBP 2010:76, 914-923

Editorial contact: Neil Madle, Varian Medical Systems, +44 7786 526068

About Varian Medical Systems

Varian Medical Systems, Inc., of Palo Alto, California, is the world's leading manufacturer of medical devices and software for treating cancer and other medical conditions with radiotherapy, radiosurgery, proton therapy, and brachytherapy. The company supplies informatics software for managing comprehensive cancer clinics, radiotherapy centers and medical oncology practices. Varian is a premier supplier of tubes and digital detectors for X-ray imaging in medical, scientific, and industrial applications and also supplies X-ray imaging products for cargo screening and industrial inspection. Varian Medical Systems employs approximately 5,000 people who are located at manufacturing sites in North America, Europe, and China and approximately 79 sales and support offices around the world. For more information, visit http://www.varian.com.

SOURCE Varian Medical Systems, Inc.

Back to top

RELATED LINKS
http://www.varian.com

'/>"/>

SOURCE Varian Medical Systems, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Researchers at Cleveland Clinic Identify Site of Dysfunction in HDL, Carrier of Good Cholesterol
2. Cleveland Clinic Researchers Identify Mechanism Behind Platelet Function and Potentially Fatal Blood Clot Formation
3. Researchers Identify Virus Possibly Responsible for Declining Honeybee Population Using 454 Sequencing Technology from Roche
4. Peregrine Researchers Report Data Showing Bavituximabs Potential to Shrink Human Prostate Tumors in Model of Relapsed Disease
5. K-State Researchers Bringing Expertise to Kansas City Symposium on Disease and National Security
6. U. of Md. Researchers to Develop Devices to Revolutionize Drug Research
7. 454 Sequencing(TM) in Science Today: Researchers Uncover a Genetic Basis for Different Social Behaviors in Wasps
8. Researchers Report First Successful Treatment of Chronic Traumatic Brain Injury
9. Potential Breakthrough Cancer Treatment Emerges from MIPS-Funded Clinical Trial Teaming CSA Medical Inc. and University of Maryland Researchers
10. Researchers Develop New Procedure to Screen All 46 Human Chromosomes to Identify Abnormalities in Embryos
11. Researchers Train the Immune System to Deliver Virus That Destroys Cancer in Lab Models
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... June 23, 2016 Research and ... Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), ... Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is projected ... CAGR of 6.1% in the forecast period 2016 to ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... "Global MEMS Devices Medical Market Analysis 2016 - Forecast to ... The report contains up to date financial ... reliable analysis. Assessment of major trends with potential impact on ... dive analysis of market segmentation which comprises of sub markets, ...
(Date:6/23/2016)... 2016 Bracket , a leading clinical trial ... clinical outcomes platform, Bracket eCOA (SM) 6.0, at the ... – 30, 2016 in Philadelphia , Pennsylvania.  ... Assessment product of its kind to fully integrate with RTSM, ... eCOA 6.0 is a flexible platform for electronic clinical outcomes ...
Breaking Medicine Technology:
(Date:6/25/2016)... ... 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, whether it’s ... setting the bar too high can result in disappointment, perhaps even self-loathing. However, those ... goal. , Research from PsychTests.com reveals that behind the tendency to ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San ... Society and the Road To Recovery® program to drive cancer patients to and from ... adults to ensure the highest quality of life and ongoing independence. Getting to ...
(Date:6/24/2016)... New York, NY (PRWEB) , ... June 24, ... ... lifestyle publication Haute Living, is proud to recognize Dr. Barry M. Weintraub as ... believes that “the most beautiful women in the world, and the most handsome ...
(Date:6/24/2016)... ... ... Venture Construction Group (VCG) sponsors Luke’s Wings 5th Annual ... Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. The event raised funds ... been wounded in battle and their families. Venture Construction Group is a 2016 Silver ...
Breaking Medicine News(10 mins):