Navigation Links
Research Highlights New Approaches to Prevent Blood Clots in Several High-Risk Patient Populations Including Largest Study Ever to Examine Use of Blood-Thinning Medication in Patients With Cancer
Date:12/7/2008

hemotherapy. The primary outcome of the study was the combined occurrence of clinically overt venous or arterial thromboembolic events (i.e., deep-vein thrombosis of the lower and upper limbs, visceral and cerebral venous thrombosis, pulmonary embolism, acute myocardial infarction, ischemic stroke, acute peripheral arterial thromboembolism, and unexplained death of possible thromboembolic origin). Major bleeding was the main safety parameter.

In this study, 1,166 patients with advanced lung (279), colon (235), breast (165), ovarian (143), stomach (98), rectal (87), pancreatic (53), head and neck (36), and other cancers (54) were randomized to one of two treatment arms: once-daily subcutaneous injections of nadroparin (3,000 IU) or placebo. Twice as many patients were enrolled into the nadroparin group than the placebo group. Treatment was started on the first day of the current cycle of chemotherapy and was maintained for the overall duration of chemotherapy treatment or up to a maximum of four months.

Only 16 of the 769 patients treated with nadroparin had a thromboembolic event (2.1 percent) compared with 15 of the 381 patients (3.9 percent) in the placebo group, a 47.2 percent reduction in the risk of developing a thromboembolic event for the patients in the treatment arm. The drug also appeared to be safe as only five patients in the nadroparin group (0.7 percent) experienced a major bleeding episode, and the incidence of minor bleeding in the treatment arm was similar to that of the placebo group.

Venous thromboembolism occurred 11 times in both the nadroparin and placebo groups. Fifteen of these events occurred in patients with lung cancer (4 percent in the nadroparin arm and 8.8 percent in the placebo arm). Patients with pancreatic cancer also experienced a high overall rate of thromboembolic events (7.5 percent). While this study confirms that nadroparin reduces the incidence of thromboembolic ev
'/>"/>

SOURCE American Society of Hematology
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. The Multiple Myeloma Research Consortium (MMRC) and Proteolix Initiate Phase 2 Clinical Trial Investigating Carfilzomib for the Treatment of Multiple Myeloma
2. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
3. Lexicon to Present Research Results at American Chemical Society Meeting Regarding Target of LX1031 Drug Candidate
4. Researchers at Cleveland Clinic Identify Site of Dysfunction in HDL, Carrier of Good Cholesterol
5. Video: New Research Discovers Independent Brain Networks Control Human Walking
6. Quark Pharmaceuticals Extends Research Agreement with State University of New York for Proprietary siRNA Compounds for Acute Hearing Loss
7. Cleveland Clinic Researchers Identify Mechanism Behind Platelet Function and Potentially Fatal Blood Clot Formation
8. HistoRx and Radiation Therapy Oncology Group Initiate Brain Tumor Biomarker Research Partnership
9. Diabetes Research Institute Invention Promotes Growth of Stem Cells into Insulin-Producing Cells
10. Researchers Identify Virus Possibly Responsible for Declining Honeybee Population Using 454 Sequencing Technology from Roche
11. Peregrine Researchers Report Data Showing Bavituximabs Potential to Shrink Human Prostate Tumors in Model of Relapsed Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... , Aug. 20, 2014 Reportlinker.com announces that ... catalogue: Global Feminine Hygiene Products Industry ... analyzes the worldwide markets for Feminine Hygiene Products in ... Tampons, Panty liners, and Others. The report provides separate ... , Japan , Europe ...
(Date:8/20/2014)... , Aug. 20, 2014 Trovagene, Inc. (NASDAQ: ... today that results from two clinical studies will be ... the Company,s urine-based diagnostic test for the detection of ... conference is scheduled to take place in ... 25 th . Additionally, a new U.S. patent was ...
(Date:8/20/2014)... 2014 Glenmark Pharmaceuticals S.A. ... Limited India (GPL), announces the discovery and initiation ... development candidate, GBR 1302, a HER2xCD3 bispecific antibody. ... Glenmark Biologics Research Centre located in La Chaux-de-Fonds, ... based on Glenmark,s innovative BEAT antibody technology platform ...
Breaking Medicine Technology:Global Feminine Hygiene Products Industry 2Global Feminine Hygiene Products Industry 3Global Feminine Hygiene Products Industry 4Global Feminine Hygiene Products Industry 5Global Feminine Hygiene Products Industry 6Global Feminine Hygiene Products Industry 7Global Feminine Hygiene Products Industry 8Global Feminine Hygiene Products Industry 9Global Feminine Hygiene Products Industry 10Global Feminine Hygiene Products Industry 11Global Feminine Hygiene Products Industry 12Global Feminine Hygiene Products Industry 13Global Feminine Hygiene Products Industry 14Global Feminine Hygiene Products Industry 15Global Feminine Hygiene Products Industry 16Global Feminine Hygiene Products Industry 17Global Feminine Hygiene Products Industry 18Global Feminine Hygiene Products Industry 19Global Feminine Hygiene Products Industry 20Global Feminine Hygiene Products Industry 21Global Feminine Hygiene Products Industry 22Global Feminine Hygiene Products Industry 23Global Feminine Hygiene Products Industry 24Global Feminine Hygiene Products Industry 25Global Feminine Hygiene Products Industry 26Trovagene Provides Update on Its Urine-Based HPV Test 2Trovagene Provides Update on Its Urine-Based HPV Test 3Glenmark Enters Oncology With the Discovery and Initiation of IND Enabling Studies of an Innovative Bispecific Antibody 2Glenmark Enters Oncology With the Discovery and Initiation of IND Enabling Studies of an Innovative Bispecific Antibody 3
(Date:8/20/2014)... The report “Automotive Airbag and Seat Belt Market ... Geography - Trends and Forecasts 2014 - 2019”, ... and seatbelt market in terms of volume and ... the coming years as well as covers review ... challenges, legislation trends, market dynamics, competitive landscape, and ...
(Date:8/20/2014)... OR (PRWEB) August 20, 2014 August ... are urged to become educated about eye health and ... examined. One frequently overlooked eye condition that must be ... Sharon Kleyne Hour Power of Water radio show, is ... children increasing exponentially, childhood dry eye is becoming a ...
(Date:8/20/2014)... Kan. (PRWEB) August 20, 2014 B. ... exclusively to healthcare providers, has been retained to lead ... Good Shepherd Health Care System in Hermiston, Ore. The ... industry, B. E. Smith has recently placed more than ... Health Care System is a progressive, not-for-profit healthcare organization ...
(Date:8/20/2014)... Hope For The Warriors® is excited ... be hosted in Washington, DC on Thursday, October 2, ... event honors the courage of our wounded service members, ... from the Got Heart, Give Hope® Celebration will benefit ... restoring a sense of self, restoring the family unit, ...
(Date:8/20/2014)... 2014 Inc. Magazine recently named ... 33rd annual Inc. 500|5000, an exclusive ranking of ... the most comprehensive look at the most important ... as Yelp, Pandora, Timberland, Dell, Domino’s Pizza, LinkedIn, ... exposure as members of the Inc. 500|5000. , ...
Breaking Medicine News(10 mins):Health News:Automotive Airbag Market Worth $23.6 Billion and Automotive Seat Belt Market Worth $9.0 Billion by 2019 – New Report by MarketsandMarkets 2Health News:Automotive Airbag Market Worth $23.6 Billion and Automotive Seat Belt Market Worth $9.0 Billion by 2019 – New Report by MarketsandMarkets 3Health News:Automotive Airbag Market Worth $23.6 Billion and Automotive Seat Belt Market Worth $9.0 Billion by 2019 – New Report by MarketsandMarkets 4Health News:August is Children’s Eye Health Month, Exams Must Check for Pediatric Dry Eye 2Health News:August is Children’s Eye Health Month, Exams Must Check for Pediatric Dry Eye 3Health News:Good Shepherd Health Care System Retains B. E. Smith to Recruit New COO 2Health News:Good Shepherd Health Care System Retains B. E. Smith to Recruit New COO 3Health News:Hope For The Warriors Announces Got Heart, Give Hope Celebration in Washington, DC 2Health News:Etransmedia Makes Exclusive List for the Eighth Consecutive Year in Inc. Magazine 2Health News:Etransmedia Makes Exclusive List for the Eighth Consecutive Year in Inc. Magazine 3
... SPRINGFIELD, Mass., Sept. 3 MassMutual,s Retirement Services ... its growing Taft-Hartley business: , , ... , William (Bill) Erlandson joined ... Scott Buffington, national sales manager for MassMutual Retirement Services ...
... , CHERRY HILL, N.J., Sept. 3 Nuvilex, ... has published a stock update featuring Nuvilex, Inc. in its September ... publisher Mr. Konrad Kuhn compared the company to a "phoenix rising from ... Nuvilex at these levels is similar to "owning an option without an ...
... , , WASHINGTON, Sept. 3 The ... , (Logo: http://www.newscom.com/cgi-bin/prnh/20090226/CENSUSLOGO ) , ... an online news conference to announce the findings from its annual report: ... . This report contains the official national findings from the Current Population ...
... -- In 1991, Ge Wang produced the first paper ... technique used in the mainstream of the medical CT ... field, and his colleagues have been awarded more than ... develop the next-generation nano-CT imaging system, which promises to ...
... FARMINGDALE, N.Y., Sept. 3 Misonix, Inc. (Nasdaq: ... medical device technology, which in Europe is used for the ... has announced its attendance at the XIV World Congress of ... Massachusetts. The World Congress, which is held every 4 ...
... - NUCRYST Pharmaceuticals, a developer and manufacturer of ... Wound Management division of Smith Nephew ... Flex3 and Acticoat(TM) Flex7. The Flex range is ... dressings with NUCRYST,s proprietary SILCRYST(TM) nanocrystalline silver coatings. ...
Cached Medicine News:Health News:MassMutual Retirement Services Adds to Taft-Hartley Sales Team 2Health News:MassMutual Retirement Services Adds to Taft-Hartley Sales Team 3Health News:The KonLin Letter Issues Featured Stock Update on Nuvilex, Inc. in Its September 2009 Edition 2Health News:The KonLin Letter Issues Featured Stock Update on Nuvilex, Inc. in Its September 2009 Edition 3Health News:The KonLin Letter Issues Featured Stock Update on Nuvilex, Inc. in Its September 2009 Edition 4Health News:Census Bureau News Media Advisory: Census Bureau to Announce Findings for Income, Earnings, Poverty and Health Insurance Coverage 2Health News:Virginia Tech's proposed next generation nano-CT system will enhance nano-scale research 2Health News:Virginia Tech's proposed next generation nano-CT system will enhance nano-scale research 3Health News:Misonix Announces Attendance At XIV World Congress of Neurological Surgery 2Health News:Misonix Announces Attendance At XIV World Congress of Neurological Surgery 3Health News:European Launch of Acticoat(TM) Flex with NUCRYST's Nanocrystalline Silver Technology Announced by Smith Nephew 2Health News:European Launch of Acticoat(TM) Flex with NUCRYST's Nanocrystalline Silver Technology Announced by Smith Nephew 3Health News:European Launch of Acticoat(TM) Flex with NUCRYST's Nanocrystalline Silver Technology Announced by Smith Nephew 4
... Pump is a syringe infusion ... the administration of many intravenous ... It provides for the convenient ... and vasoactive drugs through the ...
Developed to meet the infusion needs in NICU, Anesthesia and Critical Care, the AUTO SYRINGE AS50 Infusion Pump delivers precise, controlled infusions....
Pain management can be complicated. But that doesn't mean your PCA infusion system should be. The new SYNDEO PCA Syringe Pump streamlines pain therapy with a powerful combination of intelligent desig...
The FLO-GARD 6201 Volumetric Infusion Pump and the FLO-GARD 6301 Dual-Channel Volumetric Infusion Pump are industry standard in standard set infusion pump technology....
Medicine Products: