Navigation Links
Research Explores the Effects of Stem Cell Source and Patient Age on Stem Cell Transplantation Outcomes
Date:12/7/2008

of three types of stem cell sources: bone marrow, peripheral blood, and cord blood. Study results were based on an analysis of the outcomes of 1,240 adults with acute leukemia (707 patients with acute myeloid leukemia and 533 patients with acute lymphocytic leukemia) from 2002 to 2006. Of those patients who received a bone marrow stem cell transplant, 243 were matched at eight out of eight possible HLA loci and 111 were matched at seven HLA loci. In those receiving a peripheral blood stem cell transplant, 518 were matched at eight HLA loci and 210 at seven HLA loci. In those receiving cord blood transplants, 28 were matched at five or six HLA loci and 110 matched at four HLA loci.

The study found that there were fewer transplant-related deaths for matched peripheral blood and bone marrow transplants (27 percent and 26 percent, respectively) than as for mismatched peripheral blood, bone marrow, and cord blood transplants (42 percent, 37 percent, and 41 percent, respectively). Leukemia-free survival (LFS) and overall survival (OS) were highest after transplantation of matched peripheral blood (LFS: 43 percent; OS: 45 percent) and bone marrow (LFS: 46 percent; OS: 48 percent). These rates were lower after transplantation of mismatched peripheral blood (LFS: 33 percent; OS: 36 percent), bone marrow (LFS: 34 percent; OS: 38 percent), and cord blood (LFS: 33 percent; OS: 35 percent). Importantly, rates of transplant-related deaths, leukemia-free survival, and overall survival for the three types of mismatched transplants were similar even though cord blood transplants were mismatched at more HLA loci.

Notch-Mediated Expansion of Human Cord Blood Progenitor Cells Results in Rapid Myeloid Reconstitutionin VivoFollowing Myeloablative Cord Blood Transplantation

[Abstract #212]

C
'/>"/>

SOURCE American Society of Hematology
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. The Multiple Myeloma Research Consortium (MMRC) and Proteolix Initiate Phase 2 Clinical Trial Investigating Carfilzomib for the Treatment of Multiple Myeloma
2. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
3. Lexicon to Present Research Results at American Chemical Society Meeting Regarding Target of LX1031 Drug Candidate
4. Researchers at Cleveland Clinic Identify Site of Dysfunction in HDL, Carrier of Good Cholesterol
5. Video: New Research Discovers Independent Brain Networks Control Human Walking
6. Quark Pharmaceuticals Extends Research Agreement with State University of New York for Proprietary siRNA Compounds for Acute Hearing Loss
7. Cleveland Clinic Researchers Identify Mechanism Behind Platelet Function and Potentially Fatal Blood Clot Formation
8. HistoRx and Radiation Therapy Oncology Group Initiate Brain Tumor Biomarker Research Partnership
9. Diabetes Research Institute Invention Promotes Growth of Stem Cells into Insulin-Producing Cells
10. Researchers Identify Virus Possibly Responsible for Declining Honeybee Population Using 454 Sequencing Technology from Roche
11. Peregrine Researchers Report Data Showing Bavituximabs Potential to Shrink Human Prostate Tumors in Model of Relapsed Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2015)... DUBLIN , April 24, 2015  Perrigo Company ... announced its rejection of the unsolicited offer from Mylan ... of the outstanding shares of Perrigo for $60.00 per ... each ordinary Perrigo share (the "Offer").  ... $205.00 per share significantly undervalued the Company and its ...
(Date:4/24/2015)... , April 24, 2015  A new study shows ... costs of drugs used to slow the progression of multiple ... study led by researchers at Oregon Health & Science University ... increase in the number of MS drugs in the marketplace ... lower or stabilized costs for patients who use those drugs. ...
(Date:4/24/2015)... 24, 2015 In today,s ever-changing and ... around the world to access diverse skill sets, ... there are many areas to misstep in the ... best practices are necessary and beneficial in order ... According to research by benchmarking firm, Best Practices, ...
Breaking Medicine Technology:Perrigo Rejects Mylan Unsolicited Offer 2Perrigo Rejects Mylan Unsolicited Offer 3Perrigo Rejects Mylan Unsolicited Offer 4Researchers find alarming rise in cost of MS drugs over past two decades 2Researchers find alarming rise in cost of MS drugs over past two decades 3Researchers find alarming rise in cost of MS drugs over past two decades 4Work Around the Clock: Building Effective Global Capabilities 2
... (vRad), a technology-enabled national radiology practice, announced today ... been selected by Abbeville Area Medical Center (AAMC), ... AAMC selected vRad,s Enterprise Connect(SM), ... that was developed by radiologists for radiologists. The ...
... Royal Philips Electronics (AEX: PHI, NYSE: PHG ) ... (FFDM) solution, at four customer sites in North America, bringing ... system is on display at the 97th annual meeting of ... December 2. Mammography is the primary tool used ...
Cached Medicine Technology:vRad Selected by Abbeville Area Medical Center for PACS Replacement 2vRad Selected by Abbeville Area Medical Center for PACS Replacement 3Philips MicroDose Next Generation Mammography Solution Gains Traction with First North American Customers, Enabling Excellent Image Quality at a Low Radiation Dose 2Philips MicroDose Next Generation Mammography Solution Gains Traction with First North American Customers, Enabling Excellent Image Quality at a Low Radiation Dose 3
(Date:4/24/2015)... Vancouver, BC (PRWEB) April 24, 2015 ... Albert Yuzpe, Olive Fertility co-founder and co-director, has been ... Fertility Preservation at the Evening of Hope Gala. ... to recognize Dr. Albert Yuzpe, who has been at ... past 43 years,” says Jessica Séguin, Executive Director of ...
(Date:4/24/2015)... April 24, 2015 National Access ... and legal access to medical cannabis, is taking a ... supported when advising patients. , NAC is the first ... With a $250,000 grant, NAC will be providing 300 ... "Our goal is to help Canadians gain safe and ...
(Date:4/24/2015)... April 24, 2015 Telematics Berlin is ... automakers, tier 1 & 2 suppliers, content providers, associations ... players in the value chain, see them converge in ... not only hear from those companies currently at the ... future partners. Working on customer centric products, ParkTAG are ...
(Date:4/24/2015)... PURE Solutions, a leader in allergy travel ... Network), a highly respected education, advocacy and community out-reach ... information for a special allergy travel section ... goal for both organizations is to “make lives better” ... with asthma and allergies and by finding effective ways ...
(Date:4/24/2015)... (PRWEB) April 24, 2015 ProTube Outro is ... Pro X video editors. ProTube Outro allows editors to ... 5 video drop zones. Position, scale, and rotate pictures/videos, ... ProTube Outro uses simple borders and shadows for a ... exclusive plugin. , ProTube Outro comes packed with over 30 ...
Breaking Medicine News(10 mins):Health News:Olive Fertility Centre Co-founder, Dr Al Yuzpe, Recognized as a Pioneer in Fertility Preservation 2Health News:National Access Cannabis Gives 300 Canadian Healthcare Professionals Access to Medical Cannabis Certificate Program 2Health News:Telematics Berlin 2015’s inaugural European Automotive Start-Up Competition 2Health News:Telematics Berlin 2015’s inaugural European Automotive Start-Up Competition 3Health News:PURE Solutions Partners with Allergy and Asthma Network to Provide Allergy Travel Tips 2Health News:Pixel Film Studios, FCPX Plugin Developer Announced the Release of Protube Outro, Outro Screen Templates for Final Cut Pro X 2
... sexually transmitted infections to tell their partners// to seek ... or drugs to help reduce infection rates, says a ... an important part of managing most curable sexually transmitted ... often makes this difficult. ,Researchers analysed ...
... is in the process of doing away with a commonly ... phase out the ‘Aropax’ brand of paroxetine and bring in ... used by about 49,000 New Zealanders. ,This move ... maintains that both drugs are the same, except for the ...
... supplements of folic acid could improve the memory and ... researchers from the University of Wageningen gave a group ... acid supplements or a dummy drug for three years, ... ,The folic acid group had significantly better memories and ...
... are helping to lead a large international study // ... in an effort to determine whether exercise really is ... promoted the value of exercise for a variety of ... established as safe in the group of patients who ...
... light of new information on facial transplantation—including the psychological ... of the Royal College of Surgeons of England now ... according to a report published in the Jan. 27 ... in 2003, the Working Party concluded that facial transplantation ...
... It’s no secret why we shed tears. But exactly what our ... ,A new study sheds some light on the complex design ... film, which is made up of three distinct, microscopic layers. The ... when we cry – is sandwiched between a layer of mucus ...
Cached Medicine News:Health News:New International Study to Test Exercise in Heart Failure Patients 2Health News:New International Study to Test Exercise in Heart Failure Patients 3Health News:Royal College Issues Revised Guidelines for Face Transplantation 2Health News:Royal College Issues Revised Guidelines for Face Transplantation 3Health News:Tears Reveal Some of Their Deepest Secrets to Researchers 2Health News:Tears Reveal Some of Their Deepest Secrets to Researchers 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: