Navigation Links
Research Attributes Lack of HIV/AIDS Vaccine to Use of Chimpanzees
Date:10/6/2008

BOSTON, Oct. 6 /PRNewswire-USNewswire/ -- "A return to the use of chimpanzees in AIDS research and vaccine development is without scientific justification," according to a paper released today in the journal Alternatives to Laboratory Animals (ATLA). "An Assessment of the Role of Chimpanzees in AIDS Vaccine Research" concludes that vaccine responses in chimpanzees are not predictive of responses in humans, and that claims of chimpanzees' critical role and importance in AIDS vaccine development are without foundation.

The publication comes on the heels of recent vaccine failures in late-stage clinical trials, including one vaccine that appeared to increase vulnerability to HIV infection in human clinical trial participants, though the vaccine had proven safe and effective in tests in nonhuman primates. Yet some scientists are calling for a return to the use of chimpanzees, despite their previous failings.

Other scientists doubt that a return to their use would lead to likely success. According to the paper's author, geneticist Jarrod Bailey, Ph.D., Science Director for Project R&R: Release and Restitution for Chimpanzees in U.S. Laboratories: "At a cost of billions of dollars, most of the 85 AIDS vaccines created to date have been tested in hundreds of chimpanzees who endured decades of experiments and laboratory confinement. Almost all of these vaccines protected chimpanzees from HIV infection, but none has worked in humans. Claims of the continued importance of chimpanzee use are therefore misleading. For the millions of people at risk of AIDS, as well as the chimpanzees, we must move toward more humane and scientifically superior methods."

Chimpanzees have proven to be a failed and dangerous model for humans in not only AIDS research but in areas such as heart and cancer research as well.

In a May 2008 essay in Nature, NIAID Director and AIDS expert Dr. Anthony Fauci, when reflecting on the era of HIV/AIDS, noted: "We must learn from our missteps, build on our successes in treatment and prevention, and renew our commitment to developing the truly transforming tools that will one day put this scourge behind us."

According to Dr. Bailey, "The search for such a critically needed 'transforming tool' cannot include a return to using chimpanzees, one of the greatest 'missteps' in the history of AIDS research."

Available Topic Expert(s): For information on the listed expert(s), click appropriate link.

Theodora, Capaldo, EdD

https://profnet.prnewswire.com/Subscriber/ExpertProfile.aspx?ei=52615


'/>"/>
SOURCE NEAVS - Project R&R
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. The Multiple Myeloma Research Consortium (MMRC) and Proteolix Initiate Phase 2 Clinical Trial Investigating Carfilzomib for the Treatment of Multiple Myeloma
2. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
3. Lexicon to Present Research Results at American Chemical Society Meeting Regarding Target of LX1031 Drug Candidate
4. Researchers at Cleveland Clinic Identify Site of Dysfunction in HDL, Carrier of Good Cholesterol
5. Video: New Research Discovers Independent Brain Networks Control Human Walking
6. Quark Pharmaceuticals Extends Research Agreement with State University of New York for Proprietary siRNA Compounds for Acute Hearing Loss
7. Cleveland Clinic Researchers Identify Mechanism Behind Platelet Function and Potentially Fatal Blood Clot Formation
8. HistoRx and Radiation Therapy Oncology Group Initiate Brain Tumor Biomarker Research Partnership
9. Diabetes Research Institute Invention Promotes Growth of Stem Cells into Insulin-Producing Cells
10. Researchers Identify Virus Possibly Responsible for Declining Honeybee Population Using 454 Sequencing Technology from Roche
11. Peregrine Researchers Report Data Showing Bavituximabs Potential to Shrink Human Prostate Tumors in Model of Relapsed Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2017)... May 4, 2017  A new tight-tolerance microextrusion ... other highly-engineered materials, is being launched by Natvar, ... been developed in recent years to service a ... surgical applications. More expensive materials such as glass ... tubing due to their ability to consistently hold ...
(Date:5/3/2017)... , May 3, 2017  Kalorama Information notes ... nine percent next year and this is projected ... hematopoietic stem cell (HSCT) or bone marrow transplants ... technologies are well-suited for this task. This according ... publisher Kalorama Information. The various PCR-based methodologies, Sanger ...
(Date:5/2/2017)... and LONDON , May ... market intelligence, MarketResearch.com is pleased to announce a business ... that allows for the marketing and distribution of ... through the MarketResearch.com website. The new relationship ... complete product descriptions and tables of contents from research ...
Breaking Medicine Technology:
(Date:5/22/2017)... San Antonio, TX (PRWEB) , ... May 22, 2017 , ... ... It starts with a body squatted, stretched, jumped, toned and shaped through fitness programs. ... And it is, of course, finished off with an irresistible, radiant smile. CDA ...
(Date:5/21/2017)... ID (PRWEB) , ... May 20, 2017 , ... ... financial integration systems between ABC Financial Services and financial systems. , ... link or exported files that are electronically processed through GetLinked into their club’s ...
(Date:5/21/2017)... ... ... For more than 20 years United Cutlery has been distinguished by unique and ... to fantasy. United Cutlery has always been “Stronger. Sharper” than the competition and it ... a range of weapons and tools built for battle, the M48 line by United ...
(Date:5/19/2017)... ... May 19, 2017 , ... ... an upcoming episode of Innovations with Ed Begley, Jr., airing fourth quarter 2017 ... distributor of a clean, organic dietary supplement made from naturally occurring ingredients. Innovations ...
(Date:5/19/2017)... , ... May 19, 2017 , ... ... 2017 class of Beckman Young Investigators: , Victor Acosta, Ph.D. - University of ... University, Dan Fu, Ph.D. - University of Washington, Erik Grumstrup, Ph.D. - Montana ...
Breaking Medicine News(10 mins):